Oropharyngeal Decontamination(口咽部去污)研究综述
Oropharyngeal Decontamination 口咽部去污 - Objective To determine the cost-effectiveness of selective digestive decontamination (SDD) as compared to selective oropharyngeal decontamination (SOD) in intensive care units (ICUs) with low levels of antimicrobial resistance. [1] OBJECTIVES To quantify the effects of selective digestive tract decontamination (SDD) consisting of a mouth paste and gastro-enteral suspension, selective oropharyngeal decontamination with a mouth paste (SOD) and 1-2% chlorhexidine (CHX) mouthwash on eradication and acquisition of carriage of third generation cephalosporin-resistant Enterobacterales (3GCR-E) and carbapenem resistant Gram-negative bacteria (CR-GNB) in ICU patients. [2] Multiple individual studies of selective digestive decontamination/selective oropharyngeal decontamination (SDD/SOD) among ICU patients appear to show potent infection prevention effects. [3] BACKGROUND Selective digestive decontamination (SDD) and selective oropharyngeal decontamination (SOD) regimens appear protective against ICU-acquired overall bacteraemia. [4] 78]), current sedation score (higher scores at increased risk), current selective oropharyngeal decontamination (HR 0. [5]目的 确定选择性消化道去污 (SDD) 与选择性口咽部去污 (SOD) 在抗菌素耐药性较低的重症监护病房 (ICU) 中的成本效益。 [1] 目标 为了量化由口腔糊剂和胃肠悬浮液组成的选择性消化道去污 (SDD)、口腔膏 (SOD) 和 1-2% 洗必泰 (CHX) 漱口水对根除和获得携带ICU患者中第三代耐头孢菌素肠杆菌（3GCR-E）和耐碳青霉烯革兰氏阴性菌（CR-GNB）。 [2] 多项针对 ICU 患者的选择性消化道去污/选择性口咽去污 (SDD/SOD) 的个体研究似乎显示出有效的感染预防效果。 [3] 背景 选择性消化道去污 (SDD) 和选择性口咽去污 (SOD) 方案似乎对 ICU 获得性整体菌血症具有保护作用。 [4] 78]），当前镇静评分（评分越高，风险越高），当前选择性口咽去污（HR 0. [5]
Selective Oropharyngeal Decontamination 选择性口咽部去污
Objective To determine the cost-effectiveness of selective digestive decontamination (SDD) as compared to selective oropharyngeal decontamination (SOD) in intensive care units (ICUs) with low levels of antimicrobial resistance. [1] OBJECTIVES To quantify the effects of selective digestive tract decontamination (SDD) consisting of a mouth paste and gastro-enteral suspension, selective oropharyngeal decontamination with a mouth paste (SOD) and 1-2% chlorhexidine (CHX) mouthwash on eradication and acquisition of carriage of third generation cephalosporin-resistant Enterobacterales (3GCR-E) and carbapenem resistant Gram-negative bacteria (CR-GNB) in ICU patients. [2] Multiple individual studies of selective digestive decontamination/selective oropharyngeal decontamination (SDD/SOD) among ICU patients appear to show potent infection prevention effects. [3] BACKGROUND Selective digestive decontamination (SDD) and selective oropharyngeal decontamination (SOD) regimens appear protective against ICU-acquired overall bacteraemia. [4] 78]), current sedation score (higher scores at increased risk), current selective oropharyngeal decontamination (HR 0. [5]目的 确定选择性消化道去污 (SDD) 与选择性口咽部去污 (SOD) 在抗菌素耐药性较低的重症监护病房 (ICU) 中的成本效益。 [1] 目标 为了量化由口腔糊剂和胃肠悬浮液组成的选择性消化道去污 (SDD)、口腔膏 (SOD) 和 1-2% 洗必泰 (CHX) 漱口水对根除和获得携带ICU患者中第三代耐头孢菌素肠杆菌（3GCR-E）和耐碳青霉烯革兰氏阴性菌（CR-GNB）。 [2] 多项针对 ICU 患者的选择性消化道去污/选择性口咽去污 (SDD/SOD) 的个体研究似乎显示出有效的感染预防效果。 [3] 背景 选择性消化道去污 (SDD) 和选择性口咽去污 (SOD) 方案似乎对 ICU 获得性整体菌血症具有保护作用。 [4] 78]），当前镇静评分（评分越高，风险越高），当前选择性口咽去污（HR 0. [5]