Novel Tetracyclic(新型四环)研究综述
Novel Tetracyclic 新型四环 - The reaction was inspected synthetically to achieve the synthesis of 11 novel tetracyclic structures with moderate to very good yields (39-85%). [1] Novel tetracyclic 5-aryl-5,6-dihydroquinolino[2,1-b]quinazolin-12-ones bearing benzo-15-crown-5 ether and dimethoxyphenyl moieties were prepared by one-pot cascade synthesis involving the thermally allowed pericyclic transformations of (E)-2-(2-methoxystyryl)quinazolinones. [2] An efficient, cost-effective and environmentally benign synthesis of novel tetracyclic bis-isoxazolopyrroloquinoline derivatives has been developed via one-pot four-component reaction of 4-amino-3-methyl-5-styrylisoxazoles, dimedone, aryl glyoxal monohydrates and 5-amino-3-methylisoxazole by employing water as a reaction medium and acetic acid (AcOH) as a green promoter. [3] We propose the name "nor-allodammarane" for this novel tetracyclic 6,5 + 5,5 ring system and the name "nor-allogammacerane" for the pentacyclic 6,5 + 5,5 + 6 ring system. [4] Here we report the discovery and purification of a novel tetracyclic alkaloid secreted by the rotifer Rotaria rotatoria , which lives commensally on snails that serve as intermediate hosts for S. [5] Here, we report the purification and chemical characterization of Schistosome Paralysis Factor (SPF), a novel tetracyclic alkaloid produced by the rotifer Rotaria rotatoria. [6] Herein we report the use of metathesis to construct a novel tetracyclic core in a series of estrogen receptor degraders. [7] A series of novel tetracyclic core-containing HCV NS5A inhibitors has been discovered. [8] Here, we report the purification and chemical characterization of Schistosome Paralysis Factor (SPF), a novel tetracyclic alkaloid produced by the rotifer Rotaria rotatoria. [9]对该反应进行了综合检查，以实现 11 种新型四环结构的合成，产率中等至非常好 (39-85%)。 [1] 新型四环 5-aryl-5,6-dihydroquinolino[2,1-b]quinazolin-12-ones 带有苯并-15-crown-5 醚和二甲氧基苯基部分，通过一锅级联合成制备，包括热允许的周环转化(E)-2-(2-甲氧基苯乙烯基)喹唑啉酮。 [2] 通过 4-氨基-3-甲基-5-苯乙烯基异恶唑、二甲酮、芳基乙二醛一水合物和 5-氨基的一锅四组分反应，开发了一种高效、经济且环保的新型四环双异恶唑并吡咯并喹啉衍生物合成方法-3-甲基异恶唑，采用水作为反应介质，乙酸 (AcOH) 作为绿色促进剂。 [3] 我们建议将这种新型四环 6,5 + 5,5 环系统命名为“nor-allodammarane”，将五环 6,5 + 5,5 + 6 环系统命名为“nor-allogammacerane”。 [4] 在这里，我们报告了一种由轮虫 Rotaria rotatoria 分泌的新型四环生物碱的发现和纯化，它共生于作为 S. 中间宿主的蜗牛上。 [5] 在这里，我们报告了血吸虫麻痹因子 (SPF) 的纯化和化学表征，SPF 是一种由轮虫 Rotaria rotatoria 产生的新型四环生物碱。 [6] 在这里，我们报告了使用复分解在一系列雌激素受体降解剂中构建新的四环核心。 [7] 已经发现了一系列新的含有四环核心的HCV NS5A抑制剂。 [8] 在这里，我们报告了血吸虫麻痹因子 (SPF) 的纯化和化学表征，SPF 是一种由轮虫 Rotaria rotatoria 产生的新型四环生物碱。 [9]
novel tetracyclic alkaloid 新型四环生物碱
Here we report the discovery and purification of a novel tetracyclic alkaloid secreted by the rotifer Rotaria rotatoria , which lives commensally on snails that serve as intermediate hosts for S. [1] Here, we report the purification and chemical characterization of Schistosome Paralysis Factor (SPF), a novel tetracyclic alkaloid produced by the rotifer Rotaria rotatoria. [2] Here, we report the purification and chemical characterization of Schistosome Paralysis Factor (SPF), a novel tetracyclic alkaloid produced by the rotifer Rotaria rotatoria. [3]在这里，我们报告了一种由轮虫 Rotaria rotatoria 分泌的新型四环生物碱的发现和纯化，它共生于作为 S. 中间宿主的蜗牛上。 [1] 在这里，我们报告了血吸虫麻痹因子 (SPF) 的纯化和化学表征，SPF 是一种由轮虫 Rotaria rotatoria 产生的新型四环生物碱。 [2] 在这里，我们报告了血吸虫麻痹因子 (SPF) 的纯化和化学表征，SPF 是一种由轮虫 Rotaria rotatoria 产生的新型四环生物碱。 [3]
novel tetracyclic core 新型四环核心
Herein we report the use of metathesis to construct a novel tetracyclic core in a series of estrogen receptor degraders. [1] A series of novel tetracyclic core-containing HCV NS5A inhibitors has been discovered. [2]在这里，我们报告了使用复分解在一系列雌激素受体降解剂中构建新的四环核心。 [1] 已经发现了一系列新的含有四环核心的HCV NS5A抑制剂。 [2]