Novel Polymorphisms(新的多态性)研究综述
Novel Polymorphisms 新的多态性 - The present investigation was carried out to identify the novel polymorphisms in exon 3 region of leptin gene and exon 3 + partial intron 3 of IGF-1 gene and to analyze their association with the milk production performance in indicine and taurine crossbred (Karan Fries) cows. [1] In this paper, we propose SiNPle (Simplified Inference of Novel Polymorphisms from Large coveragE), a fast and effective software for variant calling. [2] ResultsNovel polymorphisms in the equine SLC16A1 locus have been identified (missense and 5’UTR variants: g. [3] However, other studies have revealed the presence of these and novel polymorphisms, including nonsense mutations, in men with normal spermatogenesis as well. [4] One hundred and four were novel polymorphisms, 45 in MyoD1, 2 in MyoG, 56 in MyF5, and 1 in MSTN. [5]本研究旨在鉴定瘦素基因外显子 3 区域和 IGF-1 基因外显子 3 + 部分内含子 3 的新多态性，并分析它们与牛磺酸和牛磺酸杂交 (Karan Fries) 奶牛产奶性能的关系。 . [1] 在本文中，我们提出了 SiNPle（Simplified Inference of Novel Polymorphisms from Large CoverageE），这是一种快速有效的变体调用软件。 [2] 结果马 SLC16A1 基因座中的新多态性已被鉴定（错义和 5'UTR 变体：g. [3] 然而，其他研究表明，在具有正常精子发生的男性中也存在这些和新的多态性，包括无义突变。 [4] 104个是新的多态性，45个在MyoD1，2个在MyoG，56个在MyF5，1个在MSTN。 [5]
Two Novel Polymorphisms 两种新的多态性
Furthermore, IDCM patients with two novel polymorphisms (c. [1] BACKGROUND rs11801299 and rs1380576, two novel polymorphisms in MDM4 gene, have been investigated in several different cancer types. [2]此外，IDCM 患者具有两种新的多态性（c. [1] 背景 rs11801299 和 rs1380576 是 MDM4 基因中的两个新的多态性，已在几种不同的癌症类型中进行了研究。 [2]