Novel Evidence(新证据)研究综述
Novel Evidence 新证据 - Conclusion: Our study provides a novel evidence for EcPVs infection and circulation in Chinese horses and thus lays the foundation for a systematic and detailed epidemiological study of these infections in Chinese horses. [1] This RCT builds on a successful open pilot trial conducted by our team and will provide further evaluation of a novel evidence-based treatment for pregnancy-related insomnia, which can be widely disseminated and used to treat individuals that are most in need of intervention. [2] Taken together, our results provide a novel evidence that metformin can effectively attenuate trauma-induced HO by mitigating macrophage inflammatory responses through inhibiting NF-κB signaling via SIRT1-dependent mechanisms, which favors future therapeutic investigations for trauma-related disease. [3] In the last decades, novel evidence has suggested that BPH might represent an element into the wide spectrum of disorders conforming the Metabolic Syndrome (MS). [4] Conclusions: In conclusion, several lung tissue-derived molecular signatures, highlighted in this study, might serve as novel evidence for elucidating the essential mechanisms of PAH. [5] BACKGROUND Despite prevention efforts, suicide rates continue to rise, prompting the need for novel evidence-based approaches to suicide prevention. [6] METHODS A multidisciplinary team developed a novel evidence-based process for N95 respirator re-processing and sanitation using ultraviolet (UV) light. [7] Interestingly, this study provides the novel evidence that the native and oxidized cyclic forms of the SCO-spondin-derived peptide reduce pathological factors associated with AD and restore learning and memory at both early and late disease stages. [8] Lobsters exhibit a temperature-dependent withdrawal response to immersion of tail, antennae or claws in warm water; this is novel evidence of thermal nociception for this species. [9] Conclusion These findings provide important and novel evidence that higher consumption of ultra-processed foods is associated with more rapid progression of adiposity from childhood to early adulthood. [10] Novel evidence has indicated that a competing endogenous RNA (ceRNA) mechanism may occur in AF. [11] Novel evidence is presented allowing further clarification of the mechanism of the slow-binding thymidylate synthase (TS) inhibition by N4-hydroxy-dCMP (N4-OH-dCMP). [12] Conclusions and Significance: These findings provide, in the theoretical context of consciousness, novel evidence for a reduction of regional information content as a potential systems-level mechanism of consciousness disorder in MCS and UWS. [13] Second, the authors find a novel evidence that the information from Internet forum is more superior to search frequency in volatility forecasting of stock market. [14] Our study provides essential and novel evidence for the association between hysterectomy and DM risk in women aged 30 to 49 years, which is relevant to these women and their physicians. [15] This study contributes to the growing literature of bitcoin prices with novel evidence from a large emerging economy. [16] This study provides some novel evidence of visual processing in the human brain in the free-viewing condition. [17] Thus, our present study provides a novel evidence that improved uterine endometrial receptivity and enhanced angiogenesis induced by embryo-derived chemokine CXCL12 may aid to develop a minimally-invasive therapeutic strategy for clinical treatment or supplement for the patients with repeated implantation failure with less risk. [18] Novel evidence we present argues that a loosening version of the repair mechanism must be available. [19] Conclusions This is novel evidence that suggests alcohol-induced changes in bodily states may mediate the occurrence of alcohol priming effects and highlights the potentially generative role of interoceptive mechanisms in alcohol-related behaviors. [20] Cultural attitudes that have long undermined the importance of sleep could be countered by this novel evidence. [21] Discussion This study will allow us to test and further develop a novel evidenced-based complex intervention aimed at general practice teams to expedite the diagnosis of cancer in primary care. [22] Lobsters exhibit a temperature-dependent withdrawal response to immersion of tail, antennae or claws in warm water; this is novel evidence of thermal nociception for this species. [23] Treatments have focused on symptom relief, and the increasing understanding of the pathogenesis of EB is facilitating the development of novel evidencebased therapy approaches. [24] Each study's intervention was then categorized using a novel evidence-based system of categorization, derived from the conceptual clustering framework used in machine learning. [25] Haushofer not only laid the oceanographic foundation of the “Indo-Pacific” with novel evidence in marine sciences, ethnography, and philology, but also legitimated it as a social and political space. [26] Rapid sequencing is a novel evidence‐based strategy that has the potential to dramatically improve the implementation of treatments that reduce the morbidity and mortality of patients with heart failure and a reduced ejection fraction. [27] The present study presents a novel evidence for the various biological activities of green synthesized AgNPs. [28] Therefore, we created a novel evidence-based decision tool to support EMS destination choice. [29] These results provide the novel evidence that C-MSC are a source of myofibroblasts and participate in ACM fibrotic remodeling, being highly responsive to ACM-characteristic excess TGF-β1. [30] Recently, novel evidence has supported the anti-tumourigenic potential of a mixture of trypsinogen and chymotrypsinogen. [31] Our findings are robust to the correction of potential endogeneity in the spatial weight matrix, and we provide not only novel evidence for the spatial effect of institutional differential on the domino-like spread of PTAs, but also some insights on the relationship between regionalism and multilateralism. [32] These results provide the novel evidence for understanding the function and molecular mechanism of NEAT1, and a new direction for improving the chemotherapeutic effects in PC. [33] Circ_0074491 played a suppressive role in cholesteatoma through inactivating the PI3K/Akt pathway via binding to miR-22-3p and miR-125a-5p, which provided a novel evidence for the involvement of circRNA in the development of cholesteatoma. [34] Our findings may provide a novel evidence for right-sided heart dysfunction to HA exposure. [35] These results provided the novel evidence that PTGDS may play a significant role in modulating breast cancer growth, with implications for its potential use in treating breast cancer. [36] Additionally, there is novel evidence that, for some warnings, high impulsiveness may be a factor in reduced warning efficacy, which may explain poorer cessation success in this population. [37] The implication rate of novel evidence-based treatment options was higher in the second wave. [38] This article aims to determine receptivity for advancing the Learning Healthcare System (LHS) model to a novel evidence-based health care delivery framework—Learning Health Care Community (LHCC)—in Baltimore, as a model for a national initiative. [39] These results provide a novel evidence that dioxin suppresses GH-producing cell proliferation and GH synthesis due to partly targeting DAPL1, thereby impairing offspring development. [40] The finding provides (tentative) novel evidence that training variability may benefit perceptual learning of the relatively easy tone pair and facilitate the formation of talker-independent representations of non-native tones by novice learners. [41] However, novel evidence-based approaches have opened the way for agents targeting HCM molecular substrates. [42]结论：我们的研究为中国马 EcPVs 感染和循环提供了新的证据，从而为中国马这些感染的系统和详细的流行病学研究奠定了基础。 [1] 该 RCT 建立在我们团队成功开展的一项开放式试点试验的基础上，将对妊娠相关失眠的新型循证治疗提供进一步评估，该治疗可广泛传播并用于治疗最需要干预的个体。 [2] 总之，我们的研究结果提供了一个新的证据，即二甲双胍可以通过 SIRT1 依赖性机制抑制 NF-κB 信号传导来减轻巨噬细胞炎症反应，从而有效减弱创伤诱导的 H2O，这有利于未来对创伤相关疾病的治疗研究。 [3] 在过去的几十年中，新的证据表明 BPH 可能代表了符合代谢综合征 (MS) 的广泛疾病的一个元素。 [4] 结论：总之，本研究中强调的几个肺组织衍生的分子特征可能作为阐明 PAH 基本机制的新证据。 [5] 背景 尽管采取了预防措施，但自杀率继续上升，这促使人们需要新的基于证据的自杀预防方法。 [6] 方法 一个多学科团队开发了一种新的基于证据的过程，用于使用紫外线 (UV) 进行 N95 呼吸器再处理和卫生处理。 [7] 有趣的是，这项研究提供了新的证据，表明 SCO-spondin 衍生肽的天然和氧化环状形式可减少与 AD 相关的病理因素，并在疾病早期和晚期恢复学习和记忆。 [8] 龙虾在将尾巴、触角或爪子浸入温水中时会表现出与温度相关的退缩反应；这是该物种热伤害感受的新证据。 [9] 结论 这些发现提供了重要且新颖的证据，表明超加工食品的消费量增加与肥胖从儿童期到成年早期的更快发展有关。 [10] 新的证据表明，AF 中可能发生竞争性内源性 RNA (ceRNA) 机制。 [11] 提出了新的证据，可以进一步阐明 N4-羟基-dCMP (N4-OH-dCMP) 抑制缓慢结合的胸苷酸合酶 (TS) 的机制。 [12] 结论和意义：在意识的理论背景下，这些发现为减少区域信息内容提供了新的证据，作为 MCS 和 UWS 中意识障碍的潜在系统级机制。 [13] 其次，作者发现了一个新的证据，表明互联网论坛的信息在股票市场波动预测中优于搜索频率。 [14] 我们的研究为 30 至 49 岁女性的子宫切除术与 DM 风险之间的关联提供了重要且新颖的证据，这与这些女性及其医生有关。 [15] 这项研究通过来自大型新兴经济体的新证据，为不断增长的比特币价格文献做出了贡献。 [16] 这项研究提供了一些关于人脑在自由观看条件下进行视觉处理的新证据。 [17] 因此，我们目前的研究提供了一个新的证据，表明胚胎衍生趋化因子 CXCL12 诱导的子宫内膜容受性和血管生成增强可能有助于开发一种微创治疗策略，用于临床治疗或补充风险较小的反复植入失败的患者。 [18] 我们提出的新证据表明，修复机制的松动版本必须可用。 [19] 结论 这是新的证据，表明酒精引起的身体状态变化可能介导酒精启动效应的发生，并突出了内感受机制在酒精相关行为中的潜在生成作用。 [20] 这一新证据可以反驳长期以来削弱睡眠重要性的文化态度。 [21] 讨论 这项研究将使我们能够测试并进一步开发一种新的基于证据的复杂干预措施，该干预措施针对全科医疗团队，以加快初级保健中癌症的诊断。 [22] 龙虾在将尾巴、触角或爪子浸入温水中时会表现出与温度相关的退缩反应；这是该物种热伤害感受的新证据。 [23] 治疗的重点是缓解症状，对 EB 发病机制的日益了解正在促进新的循证治疗方法的发展。 [24] 然后使用新的基于证据的分类系统对每项研究的干预进行分类，该分类系统源自机器学习中使用的概念聚类框架。 [25] Haushofer 不仅以海洋科学、人种学和语言学方面的新证据奠定了“印度洋-太平洋”的海洋学基础，而且还将其作为社会和政治空间合法化。 [26] 快速测序是一种新的循证策略，有可能显着改善治疗的实施，从而降低心力衰竭和射血分数降低患者的发病率和死亡率。 [27] 本研究为绿色合成的 AgNPs 的各种生物活性提供了新的证据。 [28] 因此，我们创建了一种新颖的基于证据的决策工具来支持 EMS 目的地选择。 [29] 这些结果提供了新的证据，表明 C-MSC 是肌成纤维细胞的来源并参与 ACM 纤维化重塑，对 ACM 特征性过量 TGF-β1 高度敏感。 [30] 最近，新的证据支持胰蛋白酶原和糜蛋白酶原混合物的抗肿瘤发生潜力。 [31] 我们的研究结果对空间权重矩阵中潜在内生性的校正是稳健的，我们不仅为制度差异对 PTA 多米诺骨牌式传播的空间效应提供了新的证据，而且