Nexin 27(不要放 27)研究综述
Nexin 27 不要放 27 - Using a mass spectrometry-based proteomics approach we identified sorting nexin 27 (SNX27) as a novel interacting partner of Tax-1. [1] Sorting nexin 27 (SNX27) influences the composition of the cellular membrane via regulation of selective endosomal recycling. [2] In T lymphocytes, DGKζ interaction with Sorting Nexin 27 (SNX27) guarantees the basal control of PKCα activation. [3] Here we report on the mass spectrometric identification of the OTULIN interactor SNX27 (sorting nexin 27), an adaptor of the endosomal retromer complex responsible for protein recycling to the cell surface. [4] BackgroundSorting Nexin 27 (SNX27) belongs to a family of sortin nexins and possesses a unique binding domain at the C-terminus which mediates protein-protein interaction in intracellular trafficking, membrane remodeling, organelle motility, and tight junctions. [5] Background: Sorting Nexin 27 (SNX27) is a 62-kDa protein localized to early endosomes and known to regulate the intracellular trafficking of ion channels and receptors. [6]使用基于质谱的蛋白质组学方法，我们将排序 nexin 27 (SNX27) 确定为 Tax-1 的新型相互作用伙伴。 [1] 排序连接蛋白 27 (SNX27) 通过调节选择性内体循环来影响细胞膜的组成。 [2] 在 T 淋巴细胞中，DGKζ 与 Sorting Nexin 27 (SNX27) 的相互作用保证了 PKCα 活化的基础控制。 [3] 在这里，我们报告了 OTULIN 相互作用子 SNX27（排序连接蛋白 27）的质谱鉴定，它是负责蛋白质循环到细胞表面的内体逆转录酶复合物的适配器。 [4] 背景Sorting Nexin 27 (SNX27) 属于sortin nexin 家族，在C 端具有独特的结合域，可介导细胞内运输、膜重塑、细胞器运动和紧密连接中的蛋白质-蛋白质相互作用。 [5] 背景：Sorting Nexin 27 (SNX27) 是一种 62 kDa 的蛋白质，定位于早期内体，已知可调节离子通道和受体的细胞内运输。 [6]
Sorting Nexin 27 不排序 27
Using a mass spectrometry-based proteomics approach we identified sorting nexin 27 (SNX27) as a novel interacting partner of Tax-1. [1] Sorting nexin 27 (SNX27) influences the composition of the cellular membrane via regulation of selective endosomal recycling. [2] In T lymphocytes, DGKζ interaction with Sorting Nexin 27 (SNX27) guarantees the basal control of PKCα activation. [3] Here we report on the mass spectrometric identification of the OTULIN interactor SNX27 (sorting nexin 27), an adaptor of the endosomal retromer complex responsible for protein recycling to the cell surface. [4] Background: Sorting Nexin 27 (SNX27) is a 62-kDa protein localized to early endosomes and known to regulate the intracellular trafficking of ion channels and receptors. [5]使用基于质谱的蛋白质组学方法，我们将排序 nexin 27 (SNX27) 确定为 Tax-1 的新型相互作用伙伴。 [1] 排序连接蛋白 27 (SNX27) 通过调节选择性内体循环来影响细胞膜的组成。 [2] 在 T 淋巴细胞中，DGKζ 与 Sorting Nexin 27 (SNX27) 的相互作用保证了 PKCα 活化的基础控制。 [3] 在这里，我们报告了 OTULIN 相互作用子 SNX27（排序连接蛋白 27）的质谱鉴定，它是负责蛋白质循环到细胞表面的内体逆转录酶复合物的适配器。 [4] 背景：Sorting Nexin 27 (SNX27) 是一种 62 kDa 的蛋白质，定位于早期内体，已知可调节离子通道和受体的细胞内运输。 [5]