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Met Kinase sentence examples within met kinase inhibitor



H2O2 induces nuclear transport of the receptor tyrosine kinase c-MET in breast cancer cells via a membrane-bound retrograde trafficking mechanism


Discovery of novel 1,2,4-triazolo-1,2,4-triazines with thiomethylpyridine hinge binders as potent c-Met kinase inhibitors.

Met Kinase sentence examples within met kinase activity



Met inhibition revokes IFNγ-induction of PD-1 ligands in MET-amplified tumours


A single-step, high-dose selection scheme reveals distinct mechanisms of acquired resistance to oncogenic kinase inhibition in cancer cells.

Met Kinase sentence examples within met kinase inhibition



Triazolopyridazine derivatives: Synthesis, cytotoxic evaluation, c-Met kinase activity and molecular docking.


Fast fluorescence in situ hybridisation for the enhanced detection of MET in non-small cell lung cancer


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Met Kinase sentence examples within met kinase play



Clustering and sampling of the c-Met conformational space: A computational drug discovery study.


Optimization techniques for novel c-Met kinase inhibitors

Met Kinase sentence examples within met kinase develop



Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking.


Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking.

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10.1200/JCO.2019.37.15_SUPPL.E14674

Differentiated pharmacokinetic and pharmacodynamic properties of a highly selective MET kinase inhibitor, OMO-1: Implications for efficacy and safety.


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10.2174/1871520619666190402153429

Synthesis of Tetrahydrobenzo[b]thiophene-3-carbohydrazide Derivatives as Potential Anti-cancer Agents and Pim-1 kinase Inhibitors.


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10.2174/1871520619666190730103425

Heterocyclization of 2-Arylidencyclohexan-1,3-dione: Synthesis of Thiophene, Thiazole and Isoxazole Derivatives with Potential Antitumor Activities.



Targeting c-MET by Tivantinib through synergistic activation of JNK/c-jun pathway in cholangiocarcinoma



Design, synthesis, and biological evaluation of 4-phenoxyquinoline derivatives as potent c-Met kinase inhibitor.


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10.1016/j.bioorg.2018.10.067

Synthesis, and anti-proliferative, Pim-1 kinase inhibitors and molecular docking of thiophenes derived from estrone.


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10.1080/10799893.2019.1676258

Prediction of cytotoxic activity of a series of 1H-pyrrolo[2,3-b]pyridine derivatives as possible inhibitors of c-Met using molecular fingerprints


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10.1200/JCO.2019.37.15_SUPPL.3062

Modular phase I/II clinical trial evaluating the selective MET-kinase inhibitor OMO-1 in patients with advanced malignancies: Safety and proof of mechanism.


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10.1080/14756366.2018.1533822

Synthesis of novel 6,7-dimethoxy-4-anilinoquinolines as potent c-Met inhibitors


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10.2174/1568026619666190712205353

Recent Progress in the Development of Small Molecule c-Met Inhibitors.


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10.1016/j.bioorg.2019.01.006

Synthesis and biological evaluation of some novel thiobenzimidazole derivatives as anti-renal cancer agents through inhibition of c-MET kinase.



Discovery of novel pyrrolo[2,3-b]pyridine derivatives bearing 4-oxoquinoline moiety as potential antitumor inhibitor.


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10.2174/1871520619666190416102144

Synthesis and Biological Evaluation of Novel 4,5,6,7-Tetrahydrobenzo[D]-Thiazol-2-Yl Derivatives Derived from Dimedone with Anti-Tumor, C-Met, Tyrosine Kinase and Pim-1 Inhibitions.


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10.1200/JCO.2019.37.15_SUPPL.9506

Correlates of overall survival (OS) in metastatic uveal melanoma (mUM) and a randomized trial of cabozantinib (cabo) versus chemotherapy (chemo).


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10.1080/07391102.2018.1479309

3D-QSAR-aided design of potent c-Met inhibitors using molecular dynamics simulation and binding free energy calculation


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10.1158/1538-7445.AM2019-1732

Abstract 1732: Switch to MET oncogene dependence as a novel mechanism of drug resistance in EGFR-mutant lung cancer



Structure based designing of triazolopyrimidone-based reversible inhibitors for kinases involved in NSCLC.


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Met Kinase 遇到激酶


Met Kinase 遇到激酶
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