Like Behavior
喜欢行为
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Like Behavior sentence examples within elevated plus maze
Blunting the naturally occurring IL-6 during pregnancy did not have a significant long-lasting impact on astrocyte cell density (GFAP), or on anxiety-like behavior as assessed with elevated plus maze and open field tests.
在怀孕期间钝化自然产生的 IL-6 对星形胶质细胞密度 (GFAP) 或焦虑样行为没有显着的长期影响,正如通过高架十字迷宫和旷场测试所评估的那样。
在怀孕期间钝化自然产生的 IL-6 对星形胶质细胞密度 (GFAP) 或焦虑样行为没有显着的长期影响,正如通过高架十字迷宫和旷场测试所评估的那样。
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The elevated plus maze test is a widely used test for assessing anxiety-like behavior and screening novel therapeutic agents in rodents.
高架十字迷宫测试是一种广泛使用的测试,用于评估啮齿动物的焦虑样行为和筛选新型治疗药物。
高架十字迷宫测试是一种广泛使用的测试,用于评估啮齿动物的焦虑样行为和筛选新型治疗药物。
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Like Behavior sentence examples within open field test
Here we used a retrovirus expressing cre recombinase in combination with an associated-adenovirus to specifically interfere with the activity of new mature aDGCs, and estimated anxiety-like behaviors by the open-field test and elevated plus maze test, antidepressant-like behaviors by the tail suspension test, and spatial memory by the Barnes maze test.
在这里,我们使用表达 cre 重组酶的逆转录病毒与相关腺病毒结合来特异性干扰新成熟 aDGC 的活性,并通过旷场试验和高架十字迷宫试验估计焦虑样行为,通过尾部悬吊测试和巴恩斯迷宫测试的空间记忆。
在这里,我们使用表达 cre 重组酶的逆转录病毒与相关腺病毒结合来特异性干扰新成熟 aDGC 的活性,并通过旷场试验和高架十字迷宫试验估计焦虑样行为,通过尾部悬吊测试和巴恩斯迷宫测试的空间记忆。
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In the cecal slurry (CS)-induced septic mouse model, we performed three different kinds of behavioral tests, open-field test, marble burying test, and forced swimming test, and observed anxiety-like behavior in septic mice.
在盲肠浆液(CS)诱导的脓毒症小鼠模型中,我们进行了三种不同的行为测试,即旷场测试、大理石掩埋测试和强迫游泳测试,并观察了脓毒症小鼠的焦虑样行为。
在盲肠浆液(CS)诱导的脓毒症小鼠模型中,我们进行了三种不同的行为测试,即旷场测试、大理石掩埋测试和强迫游泳测试,并观察了脓毒症小鼠的焦虑样行为。
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Like Behavior sentence examples within forced swim test
KEY FINDINGS
Agomelatine treatment caused significant decrease in alcohol consumption with a positive effect on anxiety-like behavior in the open field, memory in the Morris water maze and immobility in the forced swim test.
主要发现
阿戈美拉汀治疗导致饮酒量显着减少,对旷野中的焦虑样行为、莫里斯水迷宫中的记忆和强迫游泳测试中的不动有积极影响。
主要发现 阿戈美拉汀治疗导致饮酒量显着减少,对旷野中的焦虑样行为、莫里斯水迷宫中的记忆和强迫游泳测试中的不动有积极影响。
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SPS elicited significant depressive/despair like behavior on the forced swim test (FST), anxiety behavior on the elevated plus maze (EPM), as well as impaired social interaction.
SPS 在强迫游泳测试 (FST) 中引起显着的抑郁/绝望样行为、在高架十字迷宫 (EPM) 中的焦虑行为以及社交互动受损。
SPS 在强迫游泳测试 (FST) 中引起显着的抑郁/绝望样行为、在高架十字迷宫 (EPM) 中的焦虑行为以及社交互动受损。
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Like Behavior sentence examples within forced swimming test
SCZ-like behaviors were evaluated employing forced swimming test (FST), open field test (OFT), and novel object recognition test (NORT), and oxidative stress markers in the brain were estimated.
采用强迫游泳测试 (FST)、旷场测试 (OFT) 和新物体识别测试 (NORT) 评估 SCZ 样行为,并估计大脑中的氧化应激标记。
采用强迫游泳测试 (FST)、旷场测试 (OFT) 和新物体识别测试 (NORT) 评估 SCZ 样行为,并估计大脑中的氧化应激标记。
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We found that postnatal exposure to fluoxetine increased anxiety- and depression-like behaviors in the open field and sucrose preference and forced swimming tests, respectively.
我们发现,产后暴露于氟西汀分别增加了旷野和蔗糖偏好和强迫游泳测试中的焦虑和抑郁样行为。
我们发现,产后暴露于氟西汀分别增加了旷野和蔗糖偏好和强迫游泳测试中的焦虑和抑郁样行为。
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Like Behavior sentence examples within sucrose preference test
Their depression-like behavior and learning and memory ability were evaluated by sucrose preference test (SPT), open field test (OFT), and Morris water maze test (MWM).
通过蔗糖偏好测试(SPT)、旷场测试(OFT)和莫里斯水迷宫测试(MWM)评估他们的抑郁样行为和学习记忆能力。
通过蔗糖偏好测试(SPT)、旷场测试(OFT)和莫里斯水迷宫测试(MWM)评估他们的抑郁样行为和学习记忆能力。
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Besides, we examined the depression-like behaviors of rats by sucrose preference test (SPT) and forced swim test (FST).
此外,我们通过蔗糖偏好试验(SPT)和强迫游泳试验(FST)检查了大鼠的抑郁样行为。
此外,我们通过蔗糖偏好试验(SPT)和强迫游泳试验(FST)检查了大鼠的抑郁样行为。
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Like Behavior sentence examples within tail suspension test
Laboratory models for human diseases offer the possibility to evaluate depression-like behavior in mice by the tail suspension test (TST), such as the challenge of mothers with induced inflammation by lipopolysaccharide (LPS) during gestation.
人类疾病的实验室模型提供了通过悬尾试验 (TST) 评估小鼠抑郁样行为的可能性,例如母亲在妊娠期间受到脂多糖 (LPS) 诱发炎症的挑战。
人类疾病的实验室模型提供了通过悬尾试验 (TST) 评估小鼠抑郁样行为的可能性,例如母亲在妊娠期间受到脂多糖 (LPS) 诱发炎症的挑战。
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chinense could decrease depressive-like behaviors of mice, increase sucrose preference, and shorten the time of immobility in tail suspension test.
chinense可以减少小鼠的抑郁样行为,增加对蔗糖的偏好,缩短悬尾试验的不动时间。
chinense可以减少小鼠的抑郁样行为,增加对蔗糖的偏好,缩短悬尾试验的不动时间。
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Like Behavior sentence examples within chronic social defeat
AIMS
C57BL/6J mice are well-known to exhibit resilience to chronic social defeat stress (CSDS) for induction of depressive-like behavior.
目标
众所周知,C57BL/6J 小鼠表现出对慢性社交失败压力 (CSDS) 的恢复能力,可诱导抑郁样行为。
目标 众所周知,C57BL/6J 小鼠表现出对慢性社交失败压力 (CSDS) 的恢复能力,可诱导抑郁样行为。
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Deleting ErbB4 in VTA or in DA neurons, or chemical genetic inhibition of ErbB4 kinase activity in VTA suppressed the development of chronic social defeat stress (CSDS)-induced depression-like behaviors.
在 VTA 或 DA 神经元中删除 ErbB4,或在 VTA 中对 ErbB4 激酶活性的化学遗传抑制抑制了慢性社交失败压力 (CSDS) 诱导的抑郁样行为的发展。
在 VTA 或 DA 神经元中删除 ErbB4,或在 VTA 中对 ErbB4 激酶活性的化学遗传抑制抑制了慢性社交失败压力 (CSDS) 诱导的抑郁样行为的发展。
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Like Behavior sentence examples within high fat diet
Moreover, telmisartan treatment normalized high-fat diet-induced reduction of cerebral blood flow and prevented a diet-induced anxiety-like behavior.
此外,替米沙坦治疗使高脂饮食引起的脑血流量减少正常化,并防止饮食引起的焦虑样行为。
此外,替米沙坦治疗使高脂饮食引起的脑血流量减少正常化,并防止饮食引起的焦虑样行为。
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OBJECTIVE
to evaluate the influence of two maternal high-fat diets with different caloric contents on anxiety-like behavior in young-adult offspring and their sensitivity to acute fluoxetine.
客观的
评估两种不同热量含量的母体高脂肪饮食对年轻成年后代焦虑样行为及其对急性氟西汀敏感性的影响。
客观的 评估两种不同热量含量的母体高脂肪饮食对年轻成年后代焦虑样行为及其对急性氟西汀敏感性的影响。
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Like Behavior sentence examples within chronic unpredictable mild
Background: Chronic unpredictable mild stress (CUMS) can not only lead to depression-like behavior but also change the composition of the gut microbiome.
背景:慢性不可预测的轻度压力(CUMS)不仅会导致抑郁样行为,还会改变肠道微生物组的组成。
背景:慢性不可预测的轻度压力(CUMS)不仅会导致抑郁样行为,还会改变肠道微生物组的组成。
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Chronic unpredictable mild stress (CUMS) was applied for 6 weeks to induced a depressive-like behavior, characterized by decreased locomotor activity, sucrose preference and the NE, DA and 5-HT levels in cortex.
应用慢性不可预测的轻度压力 (CUMS) 6 周以诱导抑郁样行为,其特征是运动活动减少、蔗糖偏好以及皮质中的 NE、DA 和 5-HT 水平。
应用慢性不可预测的轻度压力 (CUMS) 6 周以诱导抑郁样行为,其特征是运动活动减少、蔗糖偏好以及皮质中的 NE、DA 和 5-HT 水平。
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Like Behavior sentence examples within novel object recognition
The beneficial effects of AM251 were exemplified by improved hippocampal- and cortical-dependent memory function on the novel object recognition and object in place tasks, while similar benefits on mood were shown by reductions in depressive- and anxiety-like behaviors on the forced swim test and elevated plus maze.
AM251 的有益作用体现在海马和皮质依赖的记忆功能对新物体识别和物体就地任务的改善上,而对情绪的类似益处表现在强迫游泳测试中抑郁和焦虑样行为的减少上和高架加迷宫。
AM251 的有益作用体现在海马和皮质依赖的记忆功能对新物体识别和物体就地任务的改善上,而对情绪的类似益处表现在强迫游泳测试中抑郁和焦虑样行为的减少上和高架加迷宫。
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Object-based attention, novel object recognition memory, spatial working memory, and depression-like behavior were analyzed 1 day and 2 weeks following repeated mTBI.
在重复 mTBI 后 1 天和 2 周分析基于对象的注意力、新的对象识别记忆、空间工作记忆和抑郁样行为。
在重复 mTBI 后 1 天和 2 周分析基于对象的注意力、新的对象识别记忆、空间工作记忆和抑郁样行为。
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Like Behavior sentence examples within medial prefrontal cortex
We could previously show that lentiviral overexpression of D1R in the medial prefrontal cortex (mPFC) of male adult rats and its termination induces bipolar disorder-like behavior.
我们之前可以证明,雄性成年大鼠内侧前额叶皮层 (mPFC) 中 D1R 的慢病毒过表达及其终止会诱导双相情感障碍样行为。
我们之前可以证明,雄性成年大鼠内侧前额叶皮层 (mPFC) 中 D1R 的慢病毒过表达及其终止会诱导双相情感障碍样行为。
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We show that deleting FXR1 from PVIs of medial prefrontal cortex (mPFC) leads to reduced PVI excitability, impaired mPFC gamma oscillation, and SCZ-like behaviors.
我们表明,从内侧前额叶皮层 (mPFC) 的 PVI 中删除 FXR1 会导致 PVI 兴奋性降低、mPFC 伽马振荡受损和 SCZ 样行为。
我们表明,从内侧前额叶皮层 (mPFC) 的 PVI 中删除 FXR1 会导致 PVI 兴奋性降低、mPFC 伽马振荡受损和 SCZ 样行为。
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Like Behavior sentence examples within showed increased anxiety
Findings revealed that compared to control, autistic-like offspring showed increased anxiety-like behavior, reduced social interaction, decreased locomotor activity, and impaired identification of the novel object.
研究结果显示,与对照组相比,自闭症后代表现出焦虑样行为增加、社交互动减少、运动活动减少以及对新物体的识别能力受损。
研究结果显示,与对照组相比,自闭症后代表现出焦虑样行为增加、社交互动减少、运动活动减少以及对新物体的识别能力受损。
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We previously reported that 20-week-old Otsuka Long-Evans Tokushima fatty (OLETF) rats, a model of progressive type 2 diabetes, showed increased anxiety-like behavior and regional area reductions and increased cholecystokinin-positive neurons in the corticolimbic system.
我们之前报道了 20 周大的 Otsuka Long-Evans Tokushima 脂肪 (OLETF) 大鼠,一种进行性 2 型糖尿病的模型,表现出增加的焦虑样行为和区域面积减少以及皮质边缘系统中胆囊收缩素阳性神经元的增加。
我们之前报道了 20 周大的 Otsuka Long-Evans Tokushima 脂肪 (OLETF) 大鼠,一种进行性 2 型糖尿病的模型,表现出增加的焦虑样行为和区域面积减少以及皮质边缘系统中胆囊收缩素阳性神经元的增加。
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Like Behavior sentence examples within short term memory
Specifically, female offspring had decreases in working and short-term memories while male offspring showed increases in hyperactivity and anxiety-like behaviors.
具体而言,女性后代的工作和短期记忆减少,而男性后代则表现出多动和焦虑样行为增加。
具体而言,女性后代的工作和短期记忆减少,而男性后代则表现出多动和焦虑样行为增加。
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Currently, the potential transgenerational effects of paternal morphine exposure during adolescence on anxiety-like behavior and short-term memory remains unknown.
目前,青春期父亲吗啡暴露对焦虑样行为和短期记忆的潜在跨代影响仍然未知。
目前,青春期父亲吗啡暴露对焦虑样行为和短期记忆的潜在跨代影响仍然未知。
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Like Behavior sentence examples within stress induced depressive
This study aimed to determine resveratrol’s effect on physical and psychological stress-induced depressive-like behavior.
本研究旨在确定白藜芦醇对生理和心理压力引起的抑郁样行为的影响。
本研究旨在确定白藜芦醇对生理和心理压力引起的抑郁样行为的影响。
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Fkbp5-deficient (Fkbp5−/−) mice resist stress-induced depressive and anxiety-like behaviors.
Fkbp5 缺陷 (Fkbp5−/−) 小鼠抵抗压力引起的抑郁和焦虑样行为。
Fkbp5 缺陷 (Fkbp5−/−) 小鼠抵抗压力引起的抑郁和焦虑样行为。
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Like Behavior sentence examples within exhibited increased anxiety
Like Behavior sentence examples within chronic stress induced
We here report that phosphatase and tensin homolog deleted on chromosome ten (PTEN) is a mediator for chronic stress-induced depression-like behaviors and neuronal atrophy in mice.
我们在此报告,十号染色体上缺失的磷酸酶和张力蛋白同源物 (PTEN) 是小鼠慢性应激诱导的抑郁样行为和神经元萎缩的介质。
我们在此报告,十号染色体上缺失的磷酸酶和张力蛋白同源物 (PTEN) 是小鼠慢性应激诱导的抑郁样行为和神经元萎缩的介质。
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The CD36 deficiency in CD36 −/− mice alleviated chronic stress-induced depression-like behaviors.
CD36 -/- 小鼠中的CD36缺乏减轻了慢性压力诱导的抑郁样行为。
CD36 -/- 小鼠中的CD36缺乏减轻了慢性压力诱导的抑郁样行为。
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Like Behavior sentence examples within present study examined
The present study examined the neuroprotective effects of carvacrol on lipopolysaccharide (LPS)-induced neuroinflammation, depression, and anxiety-like behavior.
本研究检查了香芹酚对脂多糖 (LPS) 诱导的神经炎症、抑郁和焦虑样行为的神经保护作用。
本研究检查了香芹酚对脂多糖 (LPS) 诱导的神经炎症、抑郁和焦虑样行为的神经保护作用。
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The present study examined the role of PI3K/Akt/mTOR pathway activity and neuroinflammatory signaling in the development of autistic-like behavior following seizures in the neonatal period.
本研究检查了 PI3K/Akt/mTOR 通路活性和神经炎症信号在新生儿癫痫发作后自闭症样行为发展中的作用。
本研究检查了 PI3K/Akt/mTOR 通路活性和神经炎症信号在新生儿癫痫发作后自闭症样行为发展中的作用。
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Like Behavior sentence examples within brain derived neurotrophic
Therefore, this study aimed to investigate the protective effects of RJ, and EE on anxiety-like behaviors, cognitive functions, and expression of hippocampal and also prefrontal cortex (PFC) brain-derived neurotrophic factor (BDNF) levels in stressed rats.
因此,本研究旨在研究 RJ 和 EE 对应激大鼠的焦虑样行为、认知功能和海马表达以及前额叶皮层 (PFC) 脑源性神经营养因子 (BDNF) 水平的保护作用。
因此,本研究旨在研究 RJ 和 EE 对应激大鼠的焦虑样行为、认知功能和海马表达以及前额叶皮层 (PFC) 脑源性神经营养因子 (BDNF) 水平的保护作用。
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We found that pair housing a healthy male with a stressed female led to emotional contagion; males gained less body weight, were anhedonic, demonstrated heightened anxiety-like behavior, had lower serum brain derived neurotrophic factor (BDNF) levels, had decreased hippocampal BDNF-stimulated tyrosine receptor kinase B (TrkB) signaling and increased pro-inflammatory cytokine expression in the hippocampus.
我们发现,将健康的男性和压力大的女性放在一起会导致情绪传染。男性体重增加较少,缺乏快感,表现出高度的焦虑样行为,血清脑源性神经营养因子 (BDNF) 水平较低,海马 BDNF 刺激的酪氨酸受体激酶 B (TrkB) 信号传导减少,促炎细胞因子表达增加海马体。
我们发现,将健康的男性和压力大的女性放在一起会导致情绪传染。男性体重增加较少,缺乏快感,表现出高度的焦虑样行为,血清脑源性神经营养因子 (BDNF) 水平较低,海马 BDNF 刺激的酪氨酸受体激酶 B (TrkB) 信号传导减少,促炎细胞因子表达增加海马体。
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Like Behavior sentence examples within induced mouse model
In the current study, the effect of montelukast on depression-like behavior in an ovalbumin (OVA)-induced mouse model was investigated.
在目前的研究中,研究了孟鲁司特对卵白蛋白 (OVA) 诱导的小鼠模型中抑郁样行为的影响。
在目前的研究中,研究了孟鲁司特对卵白蛋白 (OVA) 诱导的小鼠模型中抑郁样行为的影响。
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Intriguingly, the therapeutic effects of NaPB on autistic-like behaviors, such as repetitive behaviors, impaired sociability, and cognitive deficit also showed in the valproic acid (VPA)-induced mouse model of autism.
有趣的是,在丙戊酸(VPA)诱导的自闭症小鼠模型中,NaPB 对自闭症样行为(如重复行为、社交能力受损和认知缺陷)的治疗效果也有所体现。
有趣的是,在丙戊酸(VPA)诱导的自闭症小鼠模型中,NaPB 对自闭症样行为(如重复行为、社交能力受损和认知缺陷)的治疗效果也有所体现。
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Like Behavior sentence examples within elevated zero maze
In adulthood, anxiety-like behavior was assessed in the elevated zero maze and the presence and structural integrity of PFC perineuronal nets (PNNs) enwrapping parvalbumin (PV)-expressing interneurons was quantified.
在成年期,在升高的零迷宫中评估了类似焦虑的行为,并对表达小白蛋白 (PV) 的 PFC 神经周围网 (PNN) 的存在和结构完整性进行了量化。
在成年期,在升高的零迷宫中评估了类似焦虑的行为,并对表达小白蛋白 (PV) 的 PFC 神经周围网 (PNN) 的存在和结构完整性进行了量化。
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At the end of ADE testing, rats underwent testing in the elevated zero maze under vehicle or L-655,708 treatment for assessment of anxiety-like behavior.
在 ADE 测试结束时,大鼠在车辆或 L-655,708 治疗下的高架零迷宫中进行测试,以评估焦虑样行为。
在 ADE 测试结束时,大鼠在车辆或 L-655,708 治疗下的高架零迷宫中进行测试,以评估焦虑样行为。
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Like Behavior sentence examples within present study aimed
In light of this, the present study aimed to dive into the mechanism of action of CMI in ameliorating anhedonic- and anxiogenic-like behaviors induced by repeated corticosterone administration in mice.
有鉴于此,本研究旨在深入探讨 CMI 在改善小鼠反复使用皮质酮诱导的快感和焦虑样行为中的作用机制。
有鉴于此,本研究旨在深入探讨 CMI 在改善小鼠反复使用皮质酮诱导的快感和焦虑样行为中的作用机制。
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The present study aimed to assess Cur’s beneficial effects on depressive-like behaviors using a chronic unpredictable mild stress (CUMS) model and its possible molecular mechanisms.
本研究旨在使用慢性不可预测的轻度压力 (CUMS) 模型及其可能的分子机制来评估 Cur 对抑郁样行为的有益影响。
本研究旨在使用慢性不可预测的轻度压力 (CUMS) 模型及其可能的分子机制来评估 Cur 对抑郁样行为的有益影响。
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Like Behavior sentence examples within zero field cooled
We report the inhomogeneous magnetic state with the characteristics of spin-glass like behavior in KFeO2 from the low temperature magnetization and magnetization relaxation of zero field cooled measurements.
我们通过零场冷却测量的低温磁化和磁化弛豫报告了 KFeO2 中具有自旋玻璃样行为特征的不均匀磁态。
我们通过零场冷却测量的低温磁化和磁化弛豫报告了 KFeO2 中具有自旋玻璃样行为特征的不均匀磁态。
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This heterostructure system showed ferromagnetic properties (due to the presence of γ–Fe2O3 phase) from 5 to 300 K and a spin-glass-like behavior of magnetization versus temperature under zero-field-cooled and field-cooled conditions.
这种异质结构系统在 5 到 300 K 范围内显示出铁磁特性(由于存在 γ-Fe2O3 相),并且在零场冷却和场冷却条件下,磁化强度与温度的关系呈现出类似自旋玻璃的行为。
这种异质结构系统在 5 到 300 K 范围内显示出铁磁特性(由于存在 γ-Fe2O3 相),并且在零场冷却和场冷却条件下,磁化强度与温度的关系呈现出类似自旋玻璃的行为。
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Like Behavior sentence examples within light dark box
Alcohol drinking behavior was measured in adult male C57BL/6J mice treated with a CB1 receptor neutral antagonist AM4113 using a two-bottle choice paradigm while anxiety-like behavior was assessed in the light-dark box (LDB) test.
使用两瓶选择范例在用 CB1 受体中性拮抗剂 AM4113 治疗的成年雄性 C57BL/6J 小鼠中测量酒精饮酒行为,而在明暗盒 (LDB) 测试中评估焦虑样行为。
使用两瓶选择范例在用 CB1 受体中性拮抗剂 AM4113 治疗的成年雄性 C57BL/6J 小鼠中测量酒精饮酒行为,而在明暗盒 (LDB) 测试中评估焦虑样行为。
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Anxiety-like behavior of 445 mice across 30 CC strains was measured using the light/dark box assay and documented by video.
使用明暗盒测定法测量了 445 只小鼠在 30 个 CC 菌株中的焦虑样行为,并通过视频记录下来。
使用明暗盒测定法测量了 445 只小鼠在 30 个 CC 菌株中的焦虑样行为,并通过视频记录下来。
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Like Behavior sentence examples within novel tank diving
HFD individuals also showed increased aggression and anxiety-like behaviors in the mirror-induced aggression and novel tank diving tests, respectively.
HFD 个体在镜子诱发的攻击和新型坦克潜水测试中也分别表现出增加的攻击性和焦虑样行为。
HFD 个体在镜子诱发的攻击和新型坦克潜水测试中也分别表现出增加的攻击性和焦虑样行为。
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Anxiety-like behavior, exploratory behavior, and memory performance were measured using novel tank-diving test (NTT), Y-maze, and novel object recognition (NOR) tests.
使用新型坦克潜水测试 (NTT)、Y 迷宫和新型物体识别 (NOR) 测试测量焦虑样行为、探索行为和记忆性能。
使用新型坦克潜水测试 (NTT)、Y 迷宫和新型物体识别 (NOR) 测试测量焦虑样行为、探索行为和记忆性能。
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Like Behavior sentence examples within voluntary wheel running
First, we tested the relationship between radiation dose, blood cell counts, and fatigue-like behavior measured as voluntary wheel-running activity.
首先,我们测试了辐射剂量、血细胞计数和作为自愿车轮运行活动测量的疲劳样行为之间的关系。
首先,我们测试了辐射剂量、血细胞计数和作为自愿车轮运行活动测量的疲劳样行为之间的关系。
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We investigated the effects of chronic forced and voluntary wheel running on brain levels of serotonin (5-HT), its metabolite 5-hydroxyindoleacetic acid (5-HIAA), and anxiety-like behavioral change in rats.
我们研究了慢性强迫和自愿轮子跑步对大鼠大脑中血清素 (5-HT)、其代谢物 5-羟基吲哚乙酸 (5-HIAA) 水平和焦虑样行为变化的影响。
我们研究了慢性强迫和自愿轮子跑步对大鼠大脑中血清素 (5-HT)、其代谢物 5-羟基吲哚乙酸 (5-HIAA) 水平和焦虑样行为变化的影响。
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Like Behavior sentence examples within ventral tegmental area
Aversive stimuli inhibiting dopamine neurons in the ventral tegmental area (DAVTA neurons) induce anxiety-like behaviors.
抑制腹侧被盖区多巴胺神经元(DAVTA 神经元)的厌恶刺激会诱发焦虑样行为。
抑制腹侧被盖区多巴胺神经元(DAVTA 神经元)的厌恶刺激会诱发焦虑样行为。
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Here, we demonstrated the crucial role of cerebellar neurons projecting to the ventral tegmental area (VTA) in the chronic stress-induced development of depression-like behavior.
在这里,我们展示了投射到腹侧被盖区 (VTA) 的小脑神经元在慢性应激诱导的抑郁样行为发展中的关键作用。
在这里,我们展示了投射到腹侧被盖区 (VTA) 的小脑神经元在慢性应激诱导的抑郁样行为发展中的关键作用。
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Like Behavior sentence examples within locomotor activity anxiety
Results: Cessation of nicotine, tobacco smoke, nicotine vapor, and e-cigarette aerosol exposure leads to nicotine withdrawal symptoms such as somatic withdrawal signs, changes in locomotor activity, anxiety- and depressive-like behavior, learning and memory deficits, attention deficits, hyperalgesia, and dysphoria.
结果:停止尼古丁、烟草烟雾、尼古丁蒸汽和电子烟气溶胶暴露会导致尼古丁戒断症状,例如躯体戒断症状、运动活动变化、焦虑和抑郁样行为、学习和记忆缺陷、注意力缺陷、痛觉过敏和烦躁不安。
结果:停止尼古丁、烟草烟雾、尼古丁蒸汽和电子烟气溶胶暴露会导致尼古丁戒断症状,例如躯体戒断症状、运动活动变化、焦虑和抑郁样行为、学习和记忆缺陷、注意力缺陷、痛觉过敏和烦躁不安。
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Trehalose caused a slight reduction in increased blood glucose concentration, considerable autophagy activation, and a decrease in the neuroinflammatory response in the brain along with improvements of exploration, locomotor activity, anxiety, depressive-like behavior, and fear learning and memory in db/db mice.
海藻糖导致血糖浓度升高轻微降低,自噬激活显着,大脑中的神经炎症反应减少,同时探索、运动活动、焦虑、抑郁样行为以及恐惧学习和记忆的改善(db/db)老鼠。
海藻糖导致血糖浓度升高轻微降低,自噬激活显着,大脑中的神经炎症反应减少,同时探索、运动活动、焦虑、抑郁样行为以及恐惧学习和记忆的改善(db/db)老鼠。
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Like Behavior sentence examples within long term memory
A series of behavioral tests and intrahippocampal pilocarpine (H-PILO) microinjection at sub-convulsive and convulsive doses in a rat model demonstrated that exposure to crack cocaine during the embryonic period leads to anxiogenic-like behavior and long-term memory impairment in both genders and promotes depressive-like behavior in the female.
在大鼠模型中以亚惊厥和惊厥剂量进行的一系列行为测试和海马内毛果芸香碱 (H-PILO) 显微注射表明,在胚胎期暴露于可卡因可导致两性的焦虑样行为和长期记忆障碍并促进女性的抑郁行为。
在大鼠模型中以亚惊厥和惊厥剂量进行的一系列行为测试和海马内毛果芸香碱 (H-PILO) 显微注射表明,在胚胎期暴露于可卡因可导致两性的焦虑样行为和长期记忆障碍并促进女性的抑郁行为。
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Trp led to a normalization of the rats’ body weight almost to the control level, but increased anxiety-like behavior and decreased long-term memory.
Trp 导致大鼠体重几乎正常化到控制水平,但增加了焦虑样行为并降低了长期记忆。
Trp 导致大鼠体重几乎正常化到控制水平,但增加了焦虑样行为并降低了长期记忆。
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Like Behavior sentence examples within spared nerve injury
Therefore, we investigated the effects and underlying mechanisms of PRF on depression-like behaviors, resulting from spared nerve injury (SNI)-induced NP.
因此,我们研究了 PRF 对抑郁样行为的影响和潜在机制,这些行为是由备用神经损伤 (SNI) 诱导的 NP 引起的。
因此,我们研究了 PRF 对抑郁样行为的影响和潜在机制,这些行为是由备用神经损伤 (SNI) 诱导的 NP 引起的。
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Depression-like behaviors were tested in male and female rats with traumatic neuropathy [spared nerve injury (SNI)], and neuronal activity in the mPFC was monitored using the immediate early gene c-fos and in vivo electrophysiological recordings.
在患有创伤性神经病变 [未受保护的神经损伤 (SNI)] 的雄性和雌性大鼠中测试了抑郁样行为,并使用即时早期基因 c-fos 和体内电生理记录监测 mPFC 中的神经元活动。
在患有创伤性神经病变 [未受保护的神经损伤 (SNI)] 的雄性和雌性大鼠中测试了抑郁样行为,并使用即时早期基因 c-fos 和体内电生理记录监测 mPFC 中的神经元活动。
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Like Behavior sentence examples within open field elevated
Behavioral testing beginning 4mo post-irradiation suggested radiation and diet did not affect measures of exploration/anxiety-like behaviors (open field, elevated plus maze) or recognition of a novel object.
辐照后 4 个月开始的行为测试表明,辐射和饮食不影响探索/焦虑样行为(开阔视野、高架十字迷宫)或对新物体的识别。
辐照后 4 个月开始的行为测试表明,辐射和饮食不影响探索/焦虑样行为(开阔视野、高架十字迷宫)或对新物体的识别。
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METHODS Using Oprm1-Cre knock-in mice, we combined tracing and optogenetics with behavioral testing to investigate consequences of MHb-MOR neuron stimulation in approach/avoidance (real-time place preference), anxiety-related responses (open field, elevated plus maze and marble burying) and despair-like behavior (tail suspension).
方法 使用 Oprm1-Cre 敲入小鼠,我们将追踪和光遗传学与行为测试相结合,以研究 MHb-MOR 神经元刺激在接近/回避(实时位置偏好)、焦虑相关反应(开阔视野、高架十字迷宫)中的后果和大理石埋葬)和绝望的行为(尾巴悬垂)。
方法 使用 Oprm1-Cre 敲入小鼠,我们将追踪和光遗传学与行为测试相结合,以研究 MHb-MOR 神经元刺激在接近/回避(实时位置偏好)、焦虑相关反应(开阔视野、高架十字迷宫)中的后果和大理石埋葬)和绝望的行为(尾巴悬垂)。
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Like Behavior sentence examples within novel tank test
Their effects on anxiety-like behavior in zebrafish were then examined using the zebrafish novel tank test (NTT).
然后使用斑马鱼新型水箱试验(NTT)检查它们对斑马鱼焦虑样行为的影响。
然后使用斑马鱼新型水箱试验(NTT)检查它们对斑马鱼焦虑样行为的影响。
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In novel tank test, times spent in the lower zone by zebrafish of toxicity groups were at par but significantly higher compared to those of the control group, which indicate the development of anxiety-like behavior in all toxicity groups.
在新的水箱试验中,毒性组斑马鱼在下部区域花费的时间与对照组相比,但明显高于对照组,这表明所有毒性组都出现了焦虑样行为。
在新的水箱试验中,毒性组斑马鱼在下部区域花费的时间与对照组相比,但明显高于对照组,这表明所有毒性组都出现了焦虑样行为。
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Like Behavior sentence examples within autism spectrum disorder
SHANK2A overexpression affected pre- and postsynaptic targets and revealed a reversible, development-dependent autism spectrum disorder-like behavior.
SHANK2A 过表达影响突触前和突触后目标,并揭示了一种可逆的、发育依赖的自闭症谱系障碍样行为。
SHANK2A 过表达影响突触前和突触后目标,并揭示了一种可逆的、发育依赖的自闭症谱系障碍样行为。
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Mutations of the SHANK3 gene are found in some autism spectrum disorder (ASD) patients, and animal models harboring SHANK3 mutations exhibit a variety of ASD-like behaviors, presenting a unique opportunity to explore the underlying neuropathological mechanisms and potential pharmacological treatments.
在一些自闭症谱系障碍 (ASD) 患者中发现了 SHANK3 基因的突变,携带 SHANK3 突变的动物模型表现出多种 ASD 样行为,为探索潜在的神经病理学机制和潜在的药物治疗提供了独特的机会。
在一些自闭症谱系障碍 (ASD) 患者中发现了 SHANK3 基因的突变,携带 SHANK3 突变的动物模型表现出多种 ASD 样行为,为探索潜在的神经病理学机制和潜在的药物治疗提供了独特的机会。
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Like Behavior sentence examples within decreased locomotor activity
For example, a decreased locomotor activity as a common presentation of pain-like behavior has yet to be described.
例如,尚未描述作为疼痛样行为的常见表现的运动活动减少。
例如,尚未描述作为疼痛样行为的常见表现的运动活动减少。
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In ABA females, the separation leads to increased hyperactivity and anxiety reduction, whereas, in males, the separation induces decreased locomotor activity without similar reduction of anxiety-like behaviors as observed in females.
在 ABA 女性中,分离导致多动增加和焦虑减少,而在男性中,分离导致运动活动减少,而在女性中观察到的焦虑样行为没有类似的减少。
在 ABA 女性中,分离导致多动增加和焦虑减少,而在男性中,分离导致运动活动减少,而在女性中观察到的焦虑样行为没有类似的减少。
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Like Behavior sentence examples within mice also exhibited
These mice also exhibited a reduction in saccharin preference, indicative of anhedonic-like behavior.
这些小鼠还表现出对糖精的偏好降低,这表明了类似快感的行为。
这些小鼠还表现出对糖精的偏好降低,这表明了类似快感的行为。
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Gabrb2 knockout mice also exhibited schizophrenia-like behavior and neuroinflammation that were ameliorated by the antipsychotic drug risperidone.
Gabrb2 基因敲除小鼠还表现出精神分裂症样行为和神经炎症,抗精神病药物利培酮可改善这些行为。
Gabrb2 基因敲除小鼠还表现出精神分裂症样行为和神经炎症,抗精神病药物利培酮可改善这些行为。
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Like Behavior sentence examples within chronic constriction injury
Here, we demonstrate that pain-related depression-like behaviors are induced in a rat model of chronic constriction injury (CCI).
在这里,我们证明了在慢性收缩损伤 (CCI) 的大鼠模型中诱导了与疼痛相关的抑郁样行为。
在这里,我们证明了在慢性收缩损伤 (CCI) 的大鼠模型中诱导了与疼痛相关的抑郁样行为。
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Importantly, conditional knockout of Gpr151 in adult nociceptive sensory neurons significantly alleviated chronic constriction injury (CCI)-induced neuropathic pain-like behavior but did not affect basal nociception.
重要的是,在成人伤害性感觉神经元中条件性敲除 Gpr151 可显着减轻慢性收缩损伤 (CCI) 诱导的神经性疼痛样行为,但不影响基础伤害性感受。
重要的是,在成人伤害性感觉神经元中条件性敲除 Gpr151 可显着减轻慢性收缩损伤 (CCI) 诱导的神经性疼痛样行为,但不影响基础伤害性感受。
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Like Behavior sentence examples within % w v
BM-levan dispersions at 8% and 10% w/v accentuated the gel-like behavior and the viscosity of the levan dispersion; while the visual aspect turned similar to milk.
8% 和 10% w/v 的 BM-左聚糖分散体突出了凝胶状行为和左聚糖分散体的粘度;而视觉方面变得类似于牛奶。
8% 和 10% w/v 的 BM-左聚糖分散体突出了凝胶状行为和左聚糖分散体的粘度;而视觉方面变得类似于牛奶。
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BM-levan dispersions at 8% and 10% w/v accentuated the gel-like behavior and the viscosity of the levan dispersion, while the visual aspect turned similar to milk.
8% 和 10% w/v 的 BM-果聚糖分散体突出了果聚糖分散体的凝胶状行为和粘度,而视觉方面变得类似于牛奶。
8% 和 10% w/v 的 BM-果聚糖分散体突出了果聚糖分散体的凝胶状行为和粘度,而视觉方面变得类似于牛奶。
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Like Behavior sentence examples within chronic inflammatory pain
A rat model of CFA-induced chronic inflammatory pain displayed anxiety-like behaviors, increased the excitability of ACC PNs, and reduced inhibitory presynaptic transmission; however, the number of GAD65/67 was not altered.
CFA 诱导的慢性炎症性疼痛大鼠模型表现出焦虑样行为,增加 ACC PN 的兴奋性,减少抑制性突触前传递;然而,GAD65/67 的数量没有改变。
CFA 诱导的慢性炎症性疼痛大鼠模型表现出焦虑样行为,增加 ACC PN 的兴奋性,减少抑制性突触前传递;然而,GAD65/67 的数量没有改变。
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Conclusion: GAS is effective in the treatment of mice chronic inflammatory pain and anxiety-like behaviors.
结论:GAS对小鼠慢性炎症性疼痛及焦虑样行为的治疗效果显着。
结论:GAS对小鼠慢性炎症性疼痛及焦虑样行为的治疗效果显着。
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Like Behavior sentence examples within induced cognitive impairment
This study examined whether OST improves ovariectomy (OVX)-induced cognitive impairment, and alleviates anxiety- and depression-like behaviors induced by OVX in mice.
这项研究检查了 OST 是否能改善卵巢切除术 (OVX) 引起的认知障碍,并减轻 OVX 在小鼠中引起的焦虑和抑郁样行为。
这项研究检查了 OST 是否能改善卵巢切除术 (OVX) 引起的认知障碍,并减轻 OVX 在小鼠中引起的焦虑和抑郁样行为。
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Oral administration of donepezil combined with or without C29 (DC) or DW2009 (DD) alleviated lipopolysaccharide (LPS)-induced cognitive impairment-like behaviors more strongly than treatment with each one alone.
口服多奈哌齐联合或不联合 C29 (DC) 或 DW2009 (DD) 比单独治疗更能减轻脂多糖 (LPS) 诱导的认知障碍样行为。
口服多奈哌齐联合或不联合 C29 (DC) 或 DW2009 (DD) 比单独治疗更能减轻脂多糖 (LPS) 诱导的认知障碍样行为。
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Like Behavior sentence examples within light dark test
D-22 dose-dependently increased anxiety-like behavior in adult zebrafish exposed to the light/dark test, monotonically increasing scototaxis (dark preference), but affecting risk assessment with an inverted-U-shaped response.
D-22 剂量依赖性地增加暴露于光/暗测试的成年斑马鱼的焦虑样行为,单调增加 scototaxis(黑暗偏好),但以倒 U 形反应影响风险评估。
D-22 剂量依赖性地增加暴露于光/暗测试的成年斑马鱼的焦虑样行为,单调增加 scototaxis(黑暗偏好),但以倒 U 形反应影响风险评估。
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D-22 dose-dependently increased anxiety-like behavior in adult zebrafish exposed to the light/dark test, monotonically increasing scototaxis (dark preference), but affecting risk assessment with an inverted-U-shaped response.
D-22 剂量依赖性地增加暴露于光/暗测试的成年斑马鱼的焦虑样行为,单调增加 scototaxis(黑暗偏好),但以倒 U 形反应影响风险评估。
D-22 剂量依赖性地增加暴露于光/暗测试的成年斑马鱼的焦虑样行为,单调增加 scototaxis(黑暗偏好),但以倒 U 形反应影响风险评估。
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Like Behavior sentence examples within mice induces depressive
Experimental evidence suggests that prolonged stress in mice induces depressive-like behaviors via morphological, functional and molecular changes affecting the mesolimbic and mesocortical dopaminergic pathways.
实验证据表明,小鼠长期压力通过影响中脑边缘和中皮质多巴胺能通路的形态、功能和分子变化诱导抑郁样行为。
实验证据表明,小鼠长期压力通过影响中脑边缘和中皮质多巴胺能通路的形态、功能和分子变化诱导抑郁样行为。
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Experimental evidences suggest that prolonged stress in mice induces depressive-like behaviors via morphological, functional and molecular changes affecting the mesolimbic and mesocortical dopaminergic pathways.
实验证据表明,小鼠长期压力通过影响中脑边缘和中脑皮质多巴胺能通路的形态、功能和分子变化诱导抑郁样行为。
实验证据表明,小鼠长期压力通过影响中脑边缘和中脑皮质多巴胺能通路的形态、功能和分子变化诱导抑郁样行为。
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Like Behavior sentence examples within increased social interaction
FTY720 reduced social anxiety- and despair-like behavior as assessed by increased social interaction time and reduced time spent immobile in the Porsolt forced swim test.
FTY720 减少了社交焦虑和类似绝望的行为,这是通过增加社交互动时间和减少在 Porsolt 强迫游泳测试中不动的时间来评估的。
FTY720 减少了社交焦虑和类似绝望的行为,这是通过增加社交互动时间和减少在 Porsolt 强迫游泳测试中不动的时间来评估的。
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These mice, however, display normal survival and hyperactivity, anxiolytic-like behavior, and increased social interaction.
然而,这些小鼠表现出正常的生存和多动、抗焦虑样行为和增加的社交互动。
然而,这些小鼠表现出正常的生存和多动、抗焦虑样行为和增加的社交互动。
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Like Behavior sentence examples within 10 mg kg
We will then study the effects of the treatment with the SSRI fluoxetine (three weeks 10 mg/kg/day) in adulthood, expecting that the combination of drug treatment with the social enrichment will be more effective in recovering from depressivelike behavior than SSRI treatment alone.
然后,我们将研究成年期使用 SSRI 氟西汀(三周 10 mg/kg/天)治疗的效果,预计药物治疗与社会充实相结合比单独使用 SSRI 治疗更有效地从抑郁样行为中恢复.
然后,我们将研究成年期使用 SSRI 氟西汀(三周 10 mg/kg/天)治疗的效果,预计药物治疗与社会充实相结合比单独使用 SSRI 治疗更有效地从抑郁样行为中恢复.
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The ability of almorexant (10 mg/kg) to improve sleep-like behaviors also was assessed in a group of monkeys quantitatively identified with short-duration sleep (n = 2 males, 2 females).
almorexant (10 mg/kg) 改善睡眠样行为的能力也在一组定量鉴定为短时睡眠的猴子(n = 2 只雄性,2 只雌性)中进行了评估。
almorexant (10 mg/kg) 改善睡眠样行为的能力也在一组定量鉴定为短时睡眠的猴子(n = 2 只雄性,2 只雌性)中进行了评估。
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Like Behavior sentence examples within reduced locomotor activity
We found that adult male rats exposed to adolescent stress showed reduced locomotor activity, increased anxiety-like behaviors, enhanced contextual fear memory, elevated basal plasma ACTH levels, and enhanced HPA negative feedback inhibition, as indicated by decreased plasma ACTH levels in the dexamethasone suppression test (DST).
我们发现暴露于青春期压力的成年雄性大鼠表现出运动活动减少、焦虑样行为增加、情境恐惧记忆增强、基础血浆 ACTH 水平升高和 HPA 负反馈抑制增强,如地塞米松抑制中血浆 ACTH 水平降低所示测试(夏令时)。
我们发现暴露于青春期压力的成年雄性大鼠表现出运动活动减少、焦虑样行为增加、情境恐惧记忆增强、基础血浆 ACTH 水平升高和 HPA 负反馈抑制增强,如地塞米松抑制中血浆 ACTH 水平降低所示测试(夏令时)。
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We found that GluK2 KO and GluK5 KO mice exhibited the same phenotypes in many tests, such as reduced locomotor activity, impaired motor function, and enhanced depressive-like behavior.
我们发现 GluK2 KO 和 GluK5 KO 小鼠在许多测试中表现出相同的表型,例如运动活动减少、运动功能受损和抑郁样行为增强。
我们发现 GluK2 KO 和 GluK5 KO 小鼠在许多测试中表现出相同的表型,例如运动活动减少、运动功能受损和抑郁样行为增强。
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Like Behavior sentence examples within stress induced anxiety
Chronic oral corticosterone (CORT), a model that causes a blunted endocrine response to stress, induced anxiety- and depression-like behavior in wildtype mice and mice heterozygous for the gene coding for brain-derived neurotrophic factor (BDNF) Val66Met, a variant associated with genetic susceptibility to stress.
慢性口服皮质酮 (CORT),一种导致对压力的内分泌反应迟钝的模型,在野生型小鼠和杂合子基因编码脑源性神经营养因子 (BDNF) Val66Met 的小鼠中诱发焦虑和抑郁样行为,Val66Met 是一种相关的变体具有对压力的遗传易感性。
慢性口服皮质酮 (CORT),一种导致对压力的内分泌反应迟钝的模型,在野生型小鼠和杂合子基因编码脑源性神经营养因子 (BDNF) Val66Met 的小鼠中诱发焦虑和抑郁样行为,Val66Met 是一种相关的变体具有对压力的遗传易感性。
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CCFM6432 significantly reduced stress-induced anxiety-like behaviors, mitigated hypothalamic-pituitary-adrenal (HPA) axis hyperactivity, and reversed the abnormal expression of hippocampal phosphorylated CREB and the c-Fos protein.
CCFM6432 显着降低了压力引起的焦虑样行为,减轻了下丘脑-垂体-肾上腺 (HPA) 轴的过度活跃,并逆转了海马磷酸化 CREB 和 c-Fos 蛋白的异常表达。
CCFM6432 显着降低了压力引起的焦虑样行为,减轻了下丘脑-垂体-肾上腺 (HPA) 轴的过度活跃,并逆转了海马磷酸化 CREB 和 c-Fos 蛋白的异常表达。
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Like Behavior sentence examples within increased immobility time
RESULTS
We showed that Gadd45b knockdown induced depression-like behaviors after cerebral ischemia, including increased immobility time in the FST and TST and reduced sucrose preference.
结果
我们发现 Gadd45b 敲低在脑缺血后诱导抑郁样行为,包括增加 FST 和 TST 中的不动时间和减少蔗糖偏好。
结果 我们发现 Gadd45b 敲低在脑缺血后诱导抑郁样行为,包括增加 FST 和 TST 中的不动时间和减少蔗糖偏好。
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Behavioral analysis revealed increased immobility time in the forced swim and tail suspension tests, and decreased sucrose intake in SD mice, all indicative of depressive-like behavior.
行为分析显示,在强迫游泳和悬尾测试中,静止时间增加,SD 小鼠的蔗糖摄入量减少,所有这些都表明存在抑郁样行为。
行为分析显示,在强迫游泳和悬尾测试中,静止时间增加,SD 小鼠的蔗糖摄入量减少,所有这些都表明存在抑郁样行为。
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Like Behavior sentence examples within marble burying test
The marble burying test is a test of compulsive-like behavior in mice, and psychedelics acting as 5-HT2AR agonists can reduce digging in this test.
大理石掩埋测试是对小鼠强迫性行为的测试,作为 5-HT2AR 激动剂的迷幻剂可以减少该测试中的挖掘。
大理石掩埋测试是对小鼠强迫性行为的测试,作为 5-HT2AR 激动剂的迷幻剂可以减少该测试中的挖掘。
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We found that mice exposed to chloramphenicol showed increased repetitive and compulsive-like behavior in the marble burying test, an accurate and sensitive assay of anxiety, concomitant with decreased mitochondrial complex IV activity.
我们发现暴露于氯霉素的小鼠在大理石掩埋测试中表现出重复性和强迫性行为增加,这是一种准确而敏感的焦虑测定,伴随着线粒体复合物 IV 活性的降低。
我们发现暴露于氯霉素的小鼠在大理石掩埋测试中表现出重复性和强迫性行为增加,这是一种准确而敏感的焦虑测定,伴随着线粒体复合物 IV 活性的降低。
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Like Behavior sentence examples within spatial memory impairment
Overexpressing hTau in mouse MS (MShTau) for 6 months but not 3 months induced spatial memory impairment without changing object recognition and anxiety‐like behavior, indicating a specific and time‐dependent effect of MS‐hTau accumulation on spatial cognitive functions.
在小鼠 MS (MShTau) 中过度表达 hTau 6 个月而不是 3 个月会导致空间记忆障碍,而不会改变对象识别和焦虑样行为,这表明 MS-hTau 积累对空间认知功能具有特定且时间依赖性的影响。
在小鼠 MS (MShTau) 中过度表达 hTau 6 个月而不是 3 个月会导致空间记忆障碍,而不会改变对象识别和焦虑样行为,这表明 MS-hTau 积累对空间认知功能具有特定且时间依赖性的影响。
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CONCLUSION
The present study for the first time demonstrated that endogenous n-3 PUFAs attenuated OB-induced depression-like behaviors and spatial memory impairment through modulating serotonergic and immune function, balancing the astrocyte A1/A2 phenotypes, and normalizing PUFAs profile and membrane function.
结论
本研究首次证明,内源性 n-3 PUFAs 通过调节血清素能和免疫功能、平衡星形胶质细胞 A1/A2 表型以及使 PUFAs 谱和膜功能正常化来减轻 OB 诱导的抑郁样行为和空间记忆障碍。
结论 本研究首次证明,内源性 n-3 PUFAs 通过调节血清素能和免疫功能、平衡星形胶质细胞 A1/A2 表型以及使 PUFAs 谱和膜功能正常化来减轻 OB 诱导的抑郁样行为和空间记忆障碍。
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Like Behavior sentence examples within chronic pain induced
Thus, we evaluated the activation of α7 nAch receptors on chronic pain-induced depression-like behaviors and explored the potential mechanisms.
因此,我们评估了 α7 nAch 受体对慢性疼痛诱导的抑郁样行为的激活,并探索了潜在的机制。
因此,我们评估了 α7 nAch 受体对慢性疼痛诱导的抑郁样行为的激活,并探索了潜在的机制。
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PAM-4 reversed the decreased swimming time and number of buried marbles in CCI-treated mice, suggesting that this ligand attenuates chronic pain-induced depression-like behavior and anxiogenic-like effects.
PAM-4 逆转了 CCI 治疗小鼠游泳时间和埋藏弹珠数量的减少,表明这种配体减弱了慢性疼痛引起的抑郁样行为和焦虑样作用。
PAM-4 逆转了 CCI 治疗小鼠游泳时间和埋藏弹珠数量的减少,表明这种配体减弱了慢性疼痛引起的抑郁样行为和焦虑样作用。
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Like Behavior sentence examples within social interaction test
Our results indicated that SY treatment reverses the depressive‐like behaviors induced by CSDS as measured by the social interaction test, sucrose preference test, forced swim test, and tail suspension test.
我们的结果表明,通过社交互动测试、蔗糖偏好测试、强迫游泳测试和悬尾测试,SY 治疗逆转了由 CSDS 引起的抑郁样行为。
我们的结果表明,通过社交互动测试、蔗糖偏好测试、强迫游泳测试和悬尾测试,SY 治疗逆转了由 CSDS 引起的抑郁样行为。
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The present study found that four weeks of social isolation during adolescence impaired social recognition ability in the three-chamber test and five-trial social recognition test, and increased aggressive-like behaviors, but reduced environmental exploration, as showed in the social interaction test.
本研究发现,在三室测试和五次社会识别测试中,青春期四周的社会隔离会损害社会识别能力,并增加攻击性行为,但减少环境探索,如社会互动测试所示。
本研究发现,在三室测试和五次社会识别测试中,青春期四周的社会隔离会损害社会识别能力,并增加攻击性行为,但减少环境探索,如社会互动测试所示。
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Like Behavior sentence examples within increased sucrose consumption
Young plasma significantly improved CUMS-induced depressive-like behaviors, evidenced by the increased sucrose consumption ratio in the sucrose preference test and the reduced immobility time in the forced swimming test.
年轻血浆显着改善了 CUMS 诱导的抑郁样行为,这可以通过蔗糖偏好测试中增加的蔗糖消耗率和强迫游泳测试中减少的不动时间来证明。
年轻血浆显着改善了 CUMS 诱导的抑郁样行为,这可以通过蔗糖偏好测试中增加的蔗糖消耗率和强迫游泳测试中减少的不动时间来证明。
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We found that chronic quercetin treatment (15 mg/kg, 30 mg/kg) obviously restored the weight loss of mice caused by CUMS and alleviated CUMS-induced depression-like behaviors, such as increased sucrose consumption, improved locomotor activity and shorten immobility time.
我们发现,慢性槲皮素治疗(15 mg/kg、30 mg/kg)明显恢复了由 CUMS 引起的小鼠体重减轻,并减轻了 CUMS 引起的抑郁样行为,例如增加蔗糖消耗、改善运动活性和缩短不动时间.
我们发现,慢性槲皮素治疗(15 mg/kg、30 mg/kg)明显恢复了由 CUMS 引起的小鼠体重减轻,并减轻了 CUMS 引起的抑郁样行为,例如增加蔗糖消耗、改善运动活性和缩短不动时间.
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