Fusion Induced(融合诱导)研究综述
Fusion Induced 融合诱导 - The fast diffusion of a small solute is thus ascribed to the decoupling between the structural relaxation of solvent and the solute diffusion induced by the self-motion of the solute. [1] First, by providing evidence on international knowledge diffusion induced by migration flows between MENA and EU regions, like no other work before, the authors document the effects of migration on trade and comparative advantages. [2] Background and Objectives: Drug name confusion induced by look-alike drug names represents a serious health care management problem in practice. [3] We estimated the diffusion parameters with the highest negative correlation between pore pressure and Vs change because a negative correlation indicates pore pressure increase due to diffusion induced by groundwater load. [4] Dimaprit infusion induced a significant hypotension which declined by an average margin of 20%. [5] We further demonstrate that XACT deletion does not affect X-linked gene dosage in eroded hPSCs and that aberrant XIST RNA diffusion induced by the CRISPR activation system is independent of the presence of XACT RNA. [6] SMRT of the diffused image block is found and confusion induced by image block operations. [7] BACKGROUND Cutaneous myiasis is frequently observed; however, eosinophilic pleural effusion induced by this condition is rare. [8] The interdiffusion induced by MFA was also evidenced by the depth profile of X-ray photoelectron spectroscopy (XPS). [9] IV sildenafil infusion induced an immediate, temporary, dose-dependent reduction of pulmonary vascular resistance (38–78%) and increased both pulmonary blood flow (32–132%) and heart rate (13–49%), with limited nonlinear dose-dependent effects on systemic and pulmonary pressures. [10] SMTC infusion induced an ∼4% decrease in resting global CBF [-2. [11] We have previously shown that acute insulin infusion induced a shift in fatty acid metabolism dependent on fasting duration. [12] To address the key issue of slow computation based on thermal excitations, we propose to overlay artificial diffusion induced by an external excitation mechanism. [13] The mass transfer, diffusion and fusion induced by β-Si3N4w were considered to be the main responsible for the increase of hardness. [14] During creep testing at 250 °C, β 1 phases precipitated in the AS sample, and atomic diffusion induced the formation and widening of PFZs. [15] One possible explanation for the coexistence of both lesions in the first biopsy was portal hypoperfusion induced by the multiple HAVMs. [16] The current research was intended to evaluate the impact of 6-shogaol in rodent model of ischemic-reperfusion induced- brain injury and also assessed 6-shogaol enhanced sevoflurane's neuroprotective effects. [17] EBSD results at 1500 °C/5 min suggested that the grain boundary diffusion induced the formation of wedge-shaped triple junctions and that a reconstruction behavior occurred at the interface. [18] It is suggested that irradiation can enhance the oxide layer formation because of the enhancement of Fe and/or oxygen diffusion induced by the radiation defects in 316L steel. [19] Individually printed vertical specimens were found to have the highest mean tensile strength, owing to the high level of diffusion induced by the very short layer time. [20] (4) studied cerebral hypoperfusion induced by hyperventilation challenge in 10 healthy volunteers. [21] Investigating immune cells in the tumor revealed that [Pyr1]Apelin-13 infusion induced the accumulation of CD8+ and CD4+ T cells in central areas. [22] This confirms that carbon diffusion induced by applied heat treatment significantly influences the final microstructure of the Ti/steel interface zone. [23] Without external load, moisture migration was dominated by liquid water diffusion induced by capillary force in the first falling rate period. [24] In this paper, the authors present the theoretical explanation of sonoluminescence, which accounts for the sonofusion induced by Cherenkov radiation which is generated from tachyon pairs created from ZPF field in a collapsing water bubble, and the possible structure of a sonofusion reactor. [25] The aim of the present study was to explore effective countermeasures against cerebral hypoperfusion induced by the push—pull effect. [26] Data from LC-MS metabolomics analysis showed that intra-hippocampal TMAO infusion induced a total 207 differential metabolites, which belongs to several metabolic or signaling pathways, especially FoxO signaling pathway and retrograde endocannabinoid signaling pathway. [27] Remote ischemic conditioning (RIC), consisting of brief, intermittent extremity occlusion and reperfusion induced with an inflatable cuff, is a potential neuroprotective therapy in acute stroke. [28] Three cycles of 5-min ischemia/5-min reperfusion induced by a blood pressure cuff placed on the left upper arm served as RIPC stimulus. [29] The effect of these dipoles is through a change of the diffusion induced by a change at the nanopore of the local charge carrier density and not by a change of the local conductivity. [30] Three cycles of 5-min ischemia/5-min reperfusion induced by a blood pressure cuff placed on the upper arm of the right upper arm served as RIPC treatment at 5 min after induction of anesthesia in RIPC group. [31] Hepatic hydrothorax refers to significant serous pleural effusion induced by liver cirrhosis, and some reports have suggested that this entity is ascites transferred to the thoracic cavity via a small hole in the diaphragm. [32] CO2–CH4 mixed-gas permeability experiments at 35 °C demonstrated poor plasticization resistance; mixed-gas permselectivity negatively deviated from the pure-gas values likely, due to the enhancement of CH4 diffusion induced by mixing effects. [33] This hypoxia-treated cell model partly mimics the in vivo condition of decreased placental perfusion induced by H/R. [34] Here, we used PLX3397, a colony-stimulating factor 1 receptor inhibitor, to deplete microglia in mice with chronic cerebral hypoperfusion induced by bilateral common carotid artery stenosis (BCAS). [35] Moreover, oxygen‐glucose deprivation/reperfusion induced the BV2 microglia to polarize toward an M1 phenotype, and IMM‐H004 modulated the polarization shift from the M1 phenotype and skewed toward the M2 phenotype, followed by suppressing the excessive inflammatory response and improving recovery. [36] Numerical simulation and Peclet Number (Pe) calculations indicated that when the squeeze amplitude 0 < α < 1/2, 0 < β < 1/2, the stretch amplitude γ > 4, and Re ≥ 1, the mass transfer in the mixer was dominated by convective diffusion induced by chaotic flow. [37] Chronic cerebral hypoperfusion induced by permanent occlusion of the bilateral common carotid artery can experimentally produce cerebrovascular white matter lesions in the rat brain. [38] We hypothesize that these variations correspond to the physiologic changes in pulmonary perfusion induced during normal tidal breathing, and should therefore be present in every breathing patient. [39] In conclusion, different modes of contrast-enhanced ultrasound imaging along with histology confirmed disruption of tumor perfusion induced by AVUS therapy. [40] infusion induced an increase in catalase and glutathione peroxidase activities and a decrease in lipid peroxidation with an amelioration of cellular architecture. [41] Neosynephrine infusion induced a decrease in Eadyn (from 0. [42] A significant discrepancy in CH4 emission flux between day and night in areas covered with Kochia sieversiana indicated that enhanced diffusion induced by rising temperature was the main mechanism for CH4 transport during daytime. [43] Ischaemia‐reperfusion induced a significant decrease in ERα and ERβ expression without affecting that of G protein‐coupled oestrogen receptor, whereas BZA and E2 reversed such a decrease. [44] This balancing effect between adsorption and diffusion induced by surface curvature suggests a unique strategy to design more efficient and selective hollow nanostructured catal. [45] Previously, we showed in rat that norepinephrine (NE) superfusion induced a catecholaminergic automatic activity (CAA) occurring in repetitive bursts of action potential (AP) in isolated PV strips but not in left atria (LA). [46] Our results demonstrated that Aβ infusion induced a depressantant-like behavior observed in the tail suspension and forced swimming tests, which was reversed by NLC C treatment. [47] The results show that OTRT LBE can effectively eliminate the unphysical numerical diffusion induced by the discontinuous heat flux across the phase interface, for one-dimensional to three-dimensional solid-liquid phase change problems. [48] , water/temperature triggered BERs and the water diffusion induced “plasticization effects”, where BERs-caused stress release is characterized by a phase evolution model, while "plasticization effects" induced material relaxation is captured by the depression of relaxation time which depends on the inverse of the entropy increment. [49] The healing mechanism is ascribed to the accelerated dissociation of physical interactions, melting of polymer crystallites and chain diffusion induced by the NIR photothermal effect of carbolong embedded in the CLPUs. [50]因此，小溶质的快速扩散归因于溶剂的结构弛豫与溶质自运动引起的溶质扩散之间的解耦。 [1] 首先，通过提供由中东和北非地区和欧盟地区之间的移民流动引起的国际知识传播的证据，与以前的其他工作不同，作者记录了移民对贸易和比较优势的影响。 [2] 背景和目的：由相似的药物名称引起的药物名称混淆是实践中一个严重的医疗保健管理问题。 [3] 我们估计了孔隙压力与 Vs 变化之间具有最高负相关性的扩散参数，因为负相关性表明由于地下水负荷引起的扩散导致孔隙压力增加。 [4] Dimaprit 输注引起显着的低血压，平均下降 20%。 [5] 我们进一步证明 XACT 缺失不影响侵蚀 hPSC 中的 X 连锁基因剂量，并且由 CRISPR 激活系统诱导的异常 XIST RNA 扩散与 XACT RNA 的存在无关。 [6] 发现扩散图像块的 SMRT 并由图像块操作引起混淆。 [7] 背景经常观察到皮肤蝇蛆病。然而，由这种情况引起的嗜酸性胸腔积液很少见。 [8] X 射线光电子能谱 (XPS) 的深度剖面也证明了 MFA 引起的相互扩散。 [9] 静脉输注西地那非可立即、暂时、剂量依赖性地降低肺血管阻力（38-78%）并增加肺血流量（32-132%）和心率（13-49%），但非线性剂量有限。对全身和肺动脉压的依赖性影响。 [10] SMTC 输注导致静息全球 CBF 下降 ∼4% [-2. [11] 我们之前已经表明，急性胰岛素输注会导致脂肪酸代谢发生变化，这取决于禁食时间。 [12] 为了解决基于热激发计算缓慢的关键问题，我们建议覆盖由外部激发机制引起的人工扩散。 [13] β-Si3N4w引起的传质、扩散和融合被认为是提高硬度的主要原因。 [14] 在 250°C 的蠕变测试期间，β 1 相在 AS 样品中析出，原子扩散导致 PFZ 的形成和扩大。 [15] 第一次活检中两种病变共存的一个可能解释是多个 HAVM 引起的门静脉低灌注。 [16] 目前的研究旨在评估 6-姜烯酚在啮齿动物缺血再灌注诱导的脑损伤模型中的影响，并评估 6-姜烯酚增强的七氟醚的神经保护作用。 [17] 1500 °C/5 min的EBSD结果表明，晶界扩散诱导了楔形三结的形成，并且在界面处发生了重构行为。 [18] 有人认为，辐照可以增强氧化层的形成，因为 316L 钢中的辐射缺陷引起的 Fe 和/或氧扩散的增强。 [19] 发现单独打印的垂直试样具有最高的平均抗拉强度，这是由于非常短的层时间引起的高水平扩散。 [20] (4)研究了10名健康志愿者因过度换气引起的脑灌注不足。 [21] 研究肿瘤中的免疫细胞表明，[Pyr1]Apelin-13 输注可诱导 CD8+ 和 CD4+ T 细胞在中心区域的积累。 [22] 这证实了由应用热处理引起的碳扩散显着影响了钛/钢界面区的最终微观结构。 [23] 在没有外加载荷的情况下，在第一个下降速率期，水分迁移以毛细力引起的液态水扩散为主。 [24] 在本文中，作者提出了声致发光的理论解释，它解释了切伦科夫辐射引起的声融合，切伦科夫辐射是由水泡中 ZPF 场产生的快子对产生的，以及声融合反应堆的可能结构。 [25] 本研究的目的是探索针对推拉效应引起的脑灌注不足的有效对策。 [26] LC-MS代谢组学分析数据显示，海马内注入TMAO共诱导了207种差异代谢物，属于几种代谢或信号通路，尤其是FoxO信号通路和逆行内源性大麻素信号通路。 [27] 远程缺血调节 (RIC) 包括短暂的间歇性肢体闭塞和充气袖带诱导的再灌注，是急性中风的潜在神经保护疗法。 [28] 由放置在左上臂的血压袖带诱导的三个循环的 5 分钟缺血/5 分钟再灌注作为 RIPC 刺激。 [29] 这些偶极子的作用是通过局部电荷载流子密度的纳米孔变化而不是局部电导率的变化引起的扩散变化。 [30] RIPC组在麻醉诱导后5 min，以右上臂上臂血压袖带诱导3个周期5 min缺血/5 min再灌注为RIPC治疗。 [31] 肝性胸水是指由肝硬化引起的大量浆液性胸腔积液，有报道认为该实体是腹水通过横膈上的小孔转移到胸腔。 [32] 35°C 的 CO2–CH4 混合气体渗透实验表明抗塑化性较差；由于混合效应引起的 CH4 扩散增强，混合气体的选择性渗透率可能与纯气体值有负偏差。 [33] 这种缺氧处理的细胞模型部分模拟了由 H/R 诱导的胎盘灌注减少的体内状况。 [34] 在这里，我们使用 PLX3397（一种集落刺激因子 1 受体抑制剂）来消耗由双侧颈总动脉狭窄 (BCAS) 引起的慢性脑灌注不足小鼠的小胶质细胞。 [35] 此外，氧-葡萄糖剥夺/再灌注诱导 BV2 小胶质细胞向 M1 表型极化，IMM-H004 调节了 M1 表型的极化转变并偏向 M2 表型，随后抑制过度炎症反应并改善恢复。 [36] 数值模拟和佩克莱特数（Pe）计算表明，当挤压幅度 0 < α < 1/2、0 < β < 1/2、拉伸幅度 γ > 4、Re ≥ 1 时，混合器内的传质为以混沌流动引起的对流扩散为主。 [37] 双侧颈总动脉永久性闭塞引起的慢性脑灌注不足可实验性地在大鼠脑中产生脑血管白质病变。 [38] 我们假设这些变化对应于正常潮式呼吸期间引起的肺灌注的生理变化，因此应该存在于每个呼吸患者中。 [39] 总之，不同模式的对比增强超声成像以及组织学证实了 AVUS 治疗诱导的肿瘤灌注中断。 [40] 输注诱导过氧化氢酶和谷胱甘肽过氧化物酶活性增加，脂质过氧化减少，细胞结构改善。 [41] 新辛弗林输注导致 Eadyn 降低（从 0. [42] 地肤覆盖区昼夜 CH4 排放通量存在显着差异，表明温度升高引起的扩散增强是白天 CH4 传输的主要机制。 [43] 缺血再灌注诱导 ERα 和 ERβ 表达显着降低，而不影响 G 蛋白偶联雌激素受体的表达，而 BZA 和 E2 逆转了这种降低。 [44] 这种由表面曲率引起的吸附和扩散之间的平衡效应表明了一种独特的策略来设计更有效和选择性的中空纳米结构催化剂。 [45] 以前，我们在大鼠中发现去甲肾上腺素 (NE) 灌注诱导儿茶酚胺能自动活动 (CAA) 发生在孤立的 PV 条中的动作电位 (AP) 的重复爆发中，但在左心房 (LA) 中没有。 [46] 我们的结果表明，Aβ 输注诱导了在尾部悬吊和强迫游泳试验中观察到的类似抑制剂的行为，而 NLC C 处理可以逆转这种行为。 [47] 结果表明，对于一维到三维的固液相变问题，OTRT LBE 可以有效地消除跨相界面的不连续热通量引起的非物理数值扩散。 [48] ，水/温度触发的 BER 和水扩散引起的“塑化效应”，其中 BER 引起的应力释放以相演化模型为特征，而“塑化效应”引起的材料弛豫通过弛豫时间的降低来捕获，弛豫时间取决于熵增量的倒数。 [49] 愈合机制归因于物理相互作用的加速解离、聚合物微晶的熔化和嵌入 CLPU 中的碳隆的 NIR 光热效应引起的链扩散。 [50]
acute kidney injury 急性肾损伤
Taken together, the results of the present study suggest that PA has a protective effect on ischemia-reperfusion induced acute kidney injury in mice, which may be associated with the inhibition of ferroptosis in the kidneys through direct or indirect activation of NRF2, and upregulation of the expression of the downstream ferroptosis related proteins, GPX4, SLC7A11 and HO-1. [1] mitochondrial damage pathway are important features of ischemia/reperfusion induced-acute kidney injury (IRI-AKI). [2] Background Remote organ injury is one of the complications which are developed following ischemia-reperfusion induced acute kidney injury (AKI), dramatically increasing its mortality rate. [3] Consequently, ALR may protect renal tubule epithelial cells from ischemia/reperfusion induced acute kidney injury. [4] In an ischemia/reperfusion rat model, pretreatment of GKT137831 attenuated ischemia/reperfusion induced acute kidney injury as indicated by preserved kidney function, attenuated renal structural damage and reduced apoptotic cells. [5]综上所述，本研究结果表明 PA 对小鼠缺血再灌注诱导的急性肾损伤具有保护作用，这可能与通过直接或间接激活 NRF2 抑制肾脏铁死亡有关，上调下游铁死亡相关蛋白 GPX4、SLC7A11 和 HO-1 的表达。 [1] 线粒体损伤通路是缺血/再灌注诱导的急性肾损伤（IRI-AKI）的重要特征。 [2] 背景 远端器官损伤是缺血再灌注诱导的急性肾损伤（AKI）后发生的并发症之一，其死亡率显着增加。 [3] 因此，ALR 可以保护肾小管上皮细胞免受缺血/再灌注诱导的急性肾损伤。 [4] nan [5]
blood pressure cuff 血压袖带
Three cycles of 5 min ischemia and 5 min reperfusion induced by a blood pressure cuff served as the RIPC stimulus. [1]由血压袖带诱导的三个循环的 5 分钟缺血和 5 分钟再灌注作为 RIPC 刺激。 [1]
Cell Fusion Induced 细胞融合诱导
This allowed us to recapitulate the early replication stage of the infection mediated by the S/ACE2 interaction and to detect cell fusion induced by the interaction. [1] To gain insights into arenavirus fusion, we examined cell-cell fusion induced by the Old World Lassa virus (LASV) GPC complex. [2] We found that the levels of cellular membrane cholesterol directly correlated with the levels of cell-cell fusion induced. [3] In this review, we provide an overview of the viral and cellular factors and mechanisms identified so far in the process of cell–cell fusion induced by betaherpesviruses and discuss the possible consequences for cellular dysfunction and pathogenesis. [4] Mitotic cell fusion induced Premature Chromosome Condensation (G0-PCC) assay in human lymphocytes allows rapid detection of cytogenetic damage in interphase stage, within few hours after blood collection. [5] This allowed us to recapitulate the early replication stage of the infection mediated by the S/ACE2 interaction and to detect cell fusion induced by the interaction. [6] To gain insights into arenavirus fusion, we examined cell-cell fusion induced by the Old World Lassa virus (LASV) GPC complex. [7] Finally, we found that these same gD tail basic residues are not required for cell fusion induced by a gKsyn variant. [8] There are multiple assays to analyze the viral entry including those that focus on the cell-cell fusion induced by some viral proteins. [9] Ribavirin (RBV) and mycophenolate mofetil (MMF) inhibited cell fusion induced by hPIV-2. [10] There are multiple assays to analyze the viral entry including those that focus on the cell-cell fusion induced by some viral proteins. [11]这使我们能够概括由 S/ACE2 相互作用介导的感染的早期复制阶段，并检测由相互作用诱导的细胞融合。 [1] 为了深入了解沙粒病毒融合，我们检查了由旧世界拉沙病毒 (LASV) GPC 复合物诱导的细胞 - 细胞融合。 [2] nan [3] nan [4] nan [5] nan [6] nan [7] 最后，我们发现由 gKsyn 变体诱导的细胞融合不需要这些相同的 gD 尾碱性残基。 [8] 有多种分析方法可以分析病毒进入，包括那些专注于由某些病毒蛋白诱导的细胞-细胞融合的方法。 [9] nan [10] nan [11]
Membrane Fusion Induced
In order to use this knowledge to combat the novel coronavirus pandemic, the ability of the most effective compounds to suppress membrane fusion induced by fragments of MERS-CoV and SARS-CoV/SARS-CoV-2 fusion peptides was studied using the calcein release assay and confocal fluorescence microscopy. [1] In the present study, we identified the amino acid residue important for membrane fusion induced by the SFTSV glycoprotein (GP). [2]fusion induced acute 融合诱发急性
Taken together, the results of the present study suggest that PA has a protective effect on ischemia-reperfusion induced acute kidney injury in mice, which may be associated with the inhibition of ferroptosis in the kidneys through direct or indirect activation of NRF2, and upregulation of the expression of the downstream ferroptosis related proteins, GPX4, SLC7A11 and HO-1. [1] Previous studies showed that systemic supplementation of nicotinamide (NAM) increases renal NAD+ and reverses ischemic-reperfusion induced acute renal injury. [2] Background Remote organ injury is one of the complications which are developed following ischemia-reperfusion induced acute kidney injury (AKI), dramatically increasing its mortality rate. [3] Consequently, ALR may protect renal tubule epithelial cells from ischemia/reperfusion induced acute kidney injury. [4] In an ischemia/reperfusion rat model, pretreatment of GKT137831 attenuated ischemia/reperfusion induced acute kidney injury as indicated by preserved kidney function, attenuated renal structural damage and reduced apoptotic cells. [5] This review summarizes the results of experimental and human studies concerning the role of carnosine in kidney diseases, particularly in chronic kidney disease, ischemia/reperfusion induced acute renal failure, diabetic nephropathy and also drug-induced nephrotoxicity. [6]综上所述，本研究结果表明 PA 对小鼠缺血再灌注诱导的急性肾损伤具有保护作用，这可能与通过直接或间接激活 NRF2 抑制肾脏铁死亡有关，上调下游铁死亡相关蛋白 GPX4、SLC7A11 和 HO-1 的表达。 [1] 先前的研究表明，全身补充烟酰胺 (NAM) 可增加肾脏 NAD+ 并逆转缺血再灌注诱导的急性肾损伤。 [2] 背景 远端器官损伤是缺血再灌注诱导的急性肾损伤（AKI）后发生的并发症之一，其死亡率显着增加。 [3] 因此，ALR 可以保护肾小管上皮细胞免受缺血/再灌注诱导的急性肾损伤。 [4] nan [5] nan [6]
fusion induced stres 融合诱发应力
The model in this work, usually referred as diffusion induced stress (DIS), can predict the stresses in the active material particles which are the driving force for damage, pulverization, exfoliation and crack propagation. [1] Incorporating the influence of the aforementioned heterogeneity in a chemo-mechanical continuum description is necessary to address the diffusion induced stress field during electrochemical cycling. [2] In this paper, we propose a developed expression of chemical potential without the assumption of low deformation rate to account for the diffusion induced stress and the distribution of Li concentration in nanoparticle electrodes of lithium-ion batteries. [3] In such situation, it is commonly accompanied with high heat/diffusion flux and thermal/diffusion induced stress accordingly. [4] This paper established a reaction-diffusion-stress coupled model and investigated the stress induced voltage hysteresis with consideration of diffusion induced stress, surface effects and interparticle compression. [5] Hence a realistic estimate of diffusion induced stress (DIS) in electrode and binder through modeling entails incorporation of actual conditions on the binder surface. [6]这项工作中的模型，通常称为扩散诱导应力 (DIS)，可以预测活性材料颗粒中的应力，这是损伤、粉碎、剥落和裂纹扩展的驱动力。 [1] 将上述异质性的影响纳入化学-机械连续体描述对于解决电化学循环过程中的扩散引起的应力场是必要的。 [2] 在本文中，我们提出了一种化学势的发展表达式，而不假设低变形率来解释扩散诱导的应力和锂离子电池纳米粒子电极中锂浓度的分布。 [3] 在这种情况下，通常伴随着高热/扩散通量和相应的热/扩散诱发应力。 [4] nan [5] nan [6]
fusion induced cardiac 融合诱导心脏
Moreover, our results found downregulation of miR-126 and activation of PI3K/AKT signaling pathway in AngII infusion induced cardiac hypertrophy model. [1] Moreover, our results found downregulation of miR-126 and activation of PI3K/AKT signaling AngII infusion induced cardiac hypertrophy model. [2] This chapter discusses the mechanisms behind reperfusion induced cardiac injury while focusing on myocardial ROS types, sources and adverse effect. [3] Background/Aims: Fibroblast growth factor 21 (FGF21) plays a protective role in ischemia/reperfusion induced cardiac injury. [4]此外，我们的结果发现在 AngII 输注诱导的心脏肥大模型中 miR-126 的下调和 PI3K/AKT 信号通路的激活。 [1] 此外，我们的结果发现 miR-126 的下调和 PI3K/AKT 信号通路的激活 AngII 输注诱导的心脏肥大模型。 [2] 本章讨论再灌注导致心脏损伤的机制，同时重点关注心肌 ROS 的类型、来源和不良反应。 [3] 背景/目的：成纤维细胞生长因子 21 (FGF21) 在缺血/再灌注诱导的心脏损伤中起保护作用。 [4]
fusion induced myocardial 融合诱导心肌
The results indicate that stress responsive internally translated GJA1-20k stabilizes polymerized actin filaments to stimulate non-canonical mitochondrial fission which limits ischemic-reperfusion induced myocardial infarction. [1] Therefore, the mouse model of ischemia/reperfusion was established and the effect of PLK1 on ischemia reperfusion induced myocardial damage was investigated. [2] The results indicate that stress responsive internally translated GJA1-20k stabilizes polymerized actin filaments to stimulate non-canonical mitochondrial fission which limits ischemic-reperfusion induced myocardial infarction. [3] Ischaemic postconditioning significantly attenuated ischaemia-reperfusion induced myocardial injury manifested in the terms of decreased infarct size, LDH, CK, tissue ADMA along with increase in NO levels and DDAH enzyme activity. [4]结果表明，应激反应性内部翻译的 GJA1-20k 稳定聚合的肌动蛋白丝以刺激限制缺血再灌注诱导的心肌梗塞的非经典线粒体裂变。 [1] 因此，建立缺血/再灌注小鼠模型，研究PLK1对缺血再灌注诱导的心肌损伤的影响。