Function Caused
功能引起
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Function Caused sentence examples within life threatening organ
AIMS
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection.
目标
脓毒症被定义为由宿主对感染的反应失调引起的危及生命的器官功能障碍。
目标 脓毒症被定义为由宿主对感染的反应失调引起的危及生命的器官功能障碍。
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Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection according to the 2016 sepsis 3 definition [2].
根据 2016 年脓毒症 3 定义 [2],脓毒症被定义为由宿主对感染的反应失调引起的危及生命的器官功能障碍。
根据 2016 年脓毒症 3 定义 [2],脓毒症被定义为由宿主对感染的反应失调引起的危及生命的器官功能障碍。
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Function Caused sentence examples within dysregulated host response
Sepsis is defined as a potentially fatal organ dysfunction caused by a dysregulated host response to infection.
脓毒症被定义为由宿主对感染的反应失调引起的潜在致命的器官功能障碍。
脓毒症被定义为由宿主对感染的反应失调引起的潜在致命的器官功能障碍。
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Sepsis is defined as a life-threatening disease involving multiple organ dysfunction caused by dysregulated host responses to infection.
脓毒症被定义为一种危及生命的疾病,涉及由宿主对感染的反应失调引起的多器官功能障碍。
脓毒症被定义为一种危及生命的疾病,涉及由宿主对感染的反应失调引起的多器官功能障碍。
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Function Caused sentence examples within left ventricular systolic
The detrimental effect of LBBB on left ventricular systolic and diastolic function caused by regional delays of electrical activity leads to dyssynchronous left ventricular function and has been established in HF patients.
LBBB 对由电活动的区域延迟引起的左心室收缩和舒张功能的不利影响导致不同步的左心室功能,并已在 HF 患者中得到证实。
LBBB 对由电活动的区域延迟引起的左心室收缩和舒张功能的不利影响导致不同步的左心室功能,并已在 HF 患者中得到证实。
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Arrhythmia-induced cardiomyopathy (AIC) is characterized by left-ventricular systolic dysfunction caused by persistent arrhythmia.
心律失常诱发的心肌病 (AIC) 的特征是由持续性心律失常引起的左心室收缩功能障碍。
心律失常诱发的心肌病 (AIC) 的特征是由持续性心律失常引起的左心室收缩功能障碍。
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Function Caused sentence examples within 5 mg kg
Changes in blood pressure, heart rate, and cardiac autonomic function caused by lipopolysaccharide (LPS, 5 mg/kg i.
脂多糖(LPS,5mg/kg i. 引起的血压、心率和心脏自主神经功能的变化)
脂多糖(LPS,5mg/kg i. 引起的血压、心率和心脏自主神经功能的变化)
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Function Caused sentence examples within Brain Function Caused
Traumatic brain injury (TBI) is defined as a traumatically-induced structural brain injury or physiologicaldisruption of brain function caused by an external force.
创伤性脑损伤(TBI)被定义为由外力引起的创伤性脑结构性损伤或脑功能生理性破坏。
创伤性脑损伤(TBI)被定义为由外力引起的创伤性脑结构性损伤或脑功能生理性破坏。
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Stroke is a loss of brain function caused by the cessation of blood supply in part of the brain.
中风是由于部分大脑血液供应停止而导致的大脑功能丧失。
中风是由于部分大脑血液供应停止而导致的大脑功能丧失。
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Function Caused sentence examples within Muscle Function Caused
Impaired muscle function caused diminished flight and jump ability of Y583S/+ and T178I/+ Drosophila.
肌肉功能受损导致 Y583S/+ 和 T178I/+ 果蝇的飞行和跳跃能力下降。
肌肉功能受损导致 Y583S/+ 和 T178I/+ 果蝇的飞行和跳跃能力下降。
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This problem might be caused by damage to related nerves and masticatory muscle function caused by high-voltage electrical injury.
这个问题可能是由于高压电损伤导致相关神经和咀嚼肌功能受损引起的。
这个问题可能是由于高压电损伤导致相关神经和咀嚼肌功能受损引起的。
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Function Caused sentence examples within Motor Function Caused
Stroke is the leading cause of neurological disability in adults worldwide and involves the significant impairment of sensory-motor function caused by cerebral ischemia and subsequent neuronal death.
中风是全世界成年人神经功能障碍的主要原因,涉及由脑缺血和随后的神经元死亡引起的感觉运动功能的显着损害。
中风是全世界成年人神经功能障碍的主要原因,涉及由脑缺血和随后的神经元死亡引起的感觉运动功能的显着损害。
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The impairment of motor function caused by MPTP was also blocked in hMfn2 mice.
由 MPTP 引起的运动功能损害在 hMfn2 小鼠中也被阻断。
由 MPTP 引起的运动功能损害在 hMfn2 小鼠中也被阻断。
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Function Caused sentence examples within Protein Function Caused
The decrease or loss of protein function caused by CSNK2B mutations may be a pathogenic factor in this cohort.
CSNK2B 突变引起的蛋白质功能降低或丧失可能是该队列的致病因素。
CSNK2B 突变引起的蛋白质功能降低或丧失可能是该队列的致病因素。
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Herein, alteration of protein function caused by miRNA-185 (miR-185), an immunometabolic miRNA, was determined using activity-based protein profiling, transcriptomics, and lipidomics.
在此,使用基于活性的蛋白质分析、转录组学和脂质组学来确定由 miRNA-185 (miR-185)(一种免疫代谢 miRNA)引起的蛋白质功能改变。
在此,使用基于活性的蛋白质分析、转录组学和脂质组学来确定由 miRNA-185 (miR-185)(一种免疫代谢 miRNA)引起的蛋白质功能改变。
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Function Caused sentence examples within Immune Function Caused
Suppression of immune function caused by surgery and anesthesia may promote tumor recurrence and metastasis, thereby affecting the longterm prognosis of patients.
手术和麻醉引起的免疫功能抑制可能会促进肿瘤的复发和转移,从而影响患者的远期预后。
手术和麻醉引起的免疫功能抑制可能会促进肿瘤的复发和转移,从而影响患者的远期预后。
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The regulation of immune function caused by HCMV infection was the key factor while HCMV positive CRC patients mostly presented a state of immunosuppression.
HCMV感染引起的免疫功能调节是关键因素,而HCMV阳性结直肠癌患者大多呈现免疫抑制状态。
HCMV感染引起的免疫功能调节是关键因素,而HCMV阳性结直肠癌患者大多呈现免疫抑制状态。
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Function Caused sentence examples within Neurologic Function Caused
Surgical resection could inhibit the progressive deterioration of neurologic function caused by repetitive hemorrhage.
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Brain death is a clinical diagnosis characterized by the irreversible loss of neurologic function caused by global injury to the brain, including the brain stem.
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Function Caused sentence examples within Kidney Function Caused
End-Stage Renal Disease (ESRD) is a condition where there is a gradual (gradual) decline in kidney function caused by various kidney diseases.
终末期肾病 (ESRD) 是一种由各种肾脏疾病引起的肾功能逐渐(逐渐)下降的疾病。
终末期肾病 (ESRD) 是一种由各种肾脏疾病引起的肾功能逐渐(逐渐)下降的疾病。
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The modern scientific connotation of Qizu Xueyu syndrome in Miao medicine can be characterized by ischemia,tissue and cell damage,infection and abnormal liver and kidney function caused by smooth muscle spasm.
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Function Caused sentence examples within Endothelial Function Caused
Conclusion A-SeQDs can inhibit the apoptosis of HUVECs through the mitochondrial pathway, and effectively treat the impairment of vascular endothelial function caused by isocarbophos, which is NHE1-dependent.
结论 A-SeQDs可通过线粒体途径抑制HUVECs凋亡,有效治疗NHE1依赖性异卡磷引起的血管内皮功能损害。
结论 A-SeQDs可通过线粒体途径抑制HUVECs凋亡,有效治疗NHE1依赖性异卡磷引起的血管内皮功能损害。
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Knockdown of miR-214-3p could partially reduce the increase in ROS, restore the decreased expression of GPX4 and eNOS, and thus rescue the impaired endothelial function caused by ox-LDL.
敲低 miR-214-3p 可以部分减少 ROS 的增加,恢复降低的 GPX4 和 eNOS 的表达,从而挽救 ox-LDL 引起的内皮功能受损。
敲低 miR-214-3p 可以部分减少 ROS 的增加,恢复降低的 GPX4 和 eNOS 的表达,从而挽救 ox-LDL 引起的内皮功能受损。
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Function Caused sentence examples within Cardiac Function Caused
However, there is still no effective drug to prevent and treat the abnormal changes in cardiac function caused by aging.
但是,目前还没有有效的药物来预防和治疗衰老引起的心功能异常变化。
但是,目前还没有有效的药物来预防和治疗衰老引起的心功能异常变化。
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Current knowledge on the impairment of cardiac function caused by obesity in young adult population is lacking.
目前缺乏关于年轻人群肥胖引起的心脏功能损害的知识。
目前缺乏关于年轻人群肥胖引起的心脏功能损害的知识。
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Function Caused sentence examples within Visual Function Caused
These data add to a growing body of preclinical research that may support testing whether TUDCA may be an effective early clinical intervention against declining visual function caused by diabetic retinopathy.
这些数据增加了越来越多的临床前研究,这些研究可能支持测试 TUDCA 是否可能是一种有效的早期临床干预措施,以对抗由糖尿病视网膜病变引起的视觉功能下降。
这些数据增加了越来越多的临床前研究,这些研究可能支持测试 TUDCA 是否可能是一种有效的早期临床干预措施,以对抗由糖尿病视网膜病变引起的视觉功能下降。
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Immediate steroid therapy is recommended to possibly reduce deterioration of the visual function caused by persistent IOI.
建议立即进行类固醇治疗,以可能减少持续性 IOI 引起的视觉功能恶化。
建议立即进行类固醇治疗,以可能减少持续性 IOI 引起的视觉功能恶化。
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Function Caused sentence examples within Lung Function Caused
Background and Objective: People with substance use disorder (SUD) may be easily vulnerable to coronavirus disease-19 (COVID-19) Given the impaired lung function caused by COVID-19 may exacerbate the symptoms of patients already having preexisting opioids or central nervous system stimulants use disorder This narrative review highlights the risks of interactions between COVID-19 and SUD Methods: This article has systematically reviewed and collated relevant papers and articles identified through PubMed focusing on SUD and COVID-19 Results: SUD is characterized by an array of combined mental, physical, and behavioral symptoms, which is undoubtedly of great public health concern especially in the context of the recent advent of the COVID-19 pandemic The myriad of physiological changes caused by COVID-19 and SUD may be additive or synergistic on various organ functions, hence this review has highlighted potential challenges and possible outcomes because of these interactions Systematic delineation to parse out the combined COVID-19 and SUD pathology on a given organ function is crucial Moreover, the primary measures to tackle the COVID-19 pandemic like home confinement and lack of social support may be a significant predictor of relapse in already sober individuals, thus alternate methodologies may be needed to confine this problem Conclusion: This review highlights the importance of the intertwined epidemics interactions and proposes early measures to recognize the scope of problem at the individual level to prevent future challenges.
背景和目的:物质使用障碍 (SUD) 患者可能很容易感染冠状病毒病 19 (COVID-19) 鉴于 COVID-19 引起的肺功能受损可能会加剧已经使用阿片类药物或中枢神经系统的患者的症状兴奋剂使用障碍这篇叙述性综述强调了 COVID-19 和 SUD 方法之间相互作用的风险:本文系统地回顾和整理了通过 PubMed 确定的相关论文和文章,重点关注 SUD 和 COVID-19 结果:SUD 的特点是结合了一系列精神、身体和行为症状,这无疑是重大的公共卫生问题,尤其是在最近出现 COVID-19 大流行的背景下 COVID-19 和 SUD 引起的无数生理变化可能对各种器官产生累加或协同作用功能,因此,由于这些相互作用,本次审查强调了潜在的挑战和可能的结果在给定器官功能上解析出 COVID-19 和 SUD 病理学的组合是至关重要的此外,解决 COVID-19 大流行的主要措施,如居家禁闭和缺乏社会支持,可能是已经清醒的个体复发的重要预测因素,因此可能需要替代方法来限制这个问题结论:本综述强调了相互交织的流行病相互作用的重要性,并提出了早期措施,以识别个人层面的问题范围,以防止未来的挑战。
背景和目的:物质使用障碍 (SUD) 患者可能很容易感染冠状病毒病 19 (COVID-19) 鉴于 COVID-19 引起的肺功能受损可能会加剧已经使用阿片类药物或中枢神经系统的患者的症状兴奋剂使用障碍这篇叙述性综述强调了 COVID-19 和 SUD 方法之间相互作用的风险:本文系统地回顾和整理了通过 PubMed 确定的相关论文和文章,重点关注 SUD 和 COVID-19 结果:SUD 的特点是结合了一系列精神、身体和行为症状,这无疑是重大的公共卫生问题,尤其是在最近出现 COVID-19 大流行的背景下 COVID-19 和 SUD 引起的无数生理变化可能对各种器官产生累加或协同作用功能,因此,由于这些相互作用,本次审查强调了潜在的挑战和可能的结果在给定器官功能上解析出 COVID-19 和 SUD 病理学的组合是至关重要的此外,解决 COVID-19 大流行的主要措施,如居家禁闭和缺乏社会支持,可能是已经清醒的个体复发的重要预测因素,因此可能需要替代方法来限制这个问题结论:本综述强调了相互交织的流行病相互作用的重要性,并提出了早期措施,以识别个人层面的问题范围,以防止未来的挑战。
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Planned tracheo-bronchoscopy and tracheal toilettes are recommended to prevent critical obstruction of the airway, which can be fatal in patients with associated impairment of lung function caused by SARS-CoV-2 infection.
建议进行计划的气管-支气管镜检查和气管洗手液,以防止严重的气道阻塞,这对于由 SARS-CoV-2 感染引起的相关肺功能损害的患者可能是致命的。
建议进行计划的气管-支气管镜检查和气管洗手液,以防止严重的气道阻塞,这对于由 SARS-CoV-2 感染引起的相关肺功能损害的患者可能是致命的。
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Function Caused sentence examples within Cell Function Caused
MiR-1299 knockdown could rescue the changes in cell function caused by circ_0005232 knockdown.
MiR-1299 敲低可以挽救由 circ_0005232 敲低引起的细胞功能变化。
MiR-1299 敲低可以挽救由 circ_0005232 敲低引起的细胞功能变化。
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Nevertheless, loss of RIAM profoundly exacerbates the defects in Treg cell function caused by the talin1 (R35E,R118E) mutation.
然而,RIAM 的缺失极大地加剧了由 talin1 (R35E,R118E) 突变引起的 Treg 细胞功能缺陷。
然而,RIAM 的缺失极大地加剧了由 talin1 (R35E,R118E) 突变引起的 Treg 细胞功能缺陷。
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Function Caused sentence examples within Accommodative Function Caused
Therefore, 6-weeks consumption of the test food inhibited a decrease in the accommodative function caused by visual display terminal operation (UMIN000036989).
因此,6周食用试验食品抑制了视觉显示终端操作引起的调节功能下降(UMIN000036989)。
因此,6周食用试验食品抑制了视觉显示终端操作引起的调节功能下降(UMIN000036989)。
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Conclusions : The consumption of the supplement containing anthocyanins extracted from bilberry for 6 weeks inhibited the decrease in the accommodative function caused by oxidative stress due to VDT use.
结论 : 服用含从越橘中提取的花青素的补充剂 6 周可抑制因使用 VDT 引起的氧化应激引起的调节功能下降。
结论 : 服用含从越橘中提取的花青素的补充剂 6 周可抑制因使用 VDT 引起的氧化应激引起的调节功能下降。
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Our results suggest that (1) blast exposure can cause severe, long-term hearing loss which may be partially due to slow TM healing or altered mechanical properties of healed TMs, (2) traumatic levels of sound can still reach the inner ear and cause basal OHC loss despite middle ear dysfunction caused by TM rupture, (3) blast exposure may result in synaptopathy in humans, and (4) balance deficits after blast exposure may be primarily due to traumatic brain injury, rather than damage to the peripheral vestibular system.
我们的研究结果表明(1)爆炸暴露会导致严重的长期听力损失,这可能部分是由于 TM 愈合缓慢或已愈合 TM 的机械特性发生改变,(2)创伤性声音仍然可以到达内耳并导致尽管 TM 破裂导致中耳功能障碍,但基础 OHC 损失,(3) 爆炸暴露可能导致人类突触病,以及 (4) 爆炸暴露后的平衡缺陷可能主要是由于创伤性脑损伤,而不是对周围前庭系统的损害.
我们的研究结果表明(1)爆炸暴露会导致严重的长期听力损失,这可能部分是由于 TM 愈合缓慢或已愈合 TM 的机械特性发生改变,(2)创伤性声音仍然可以到达内耳并导致尽管 TM 破裂导致中耳功能障碍,但基础 OHC 损失,(3) 爆炸暴露可能导致人类突触病,以及 (4) 爆炸暴露后的平衡缺陷可能主要是由于创伤性脑损伤,而不是对周围前庭系统的损害.
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Moreover, inhibition of c-Myc transcriptional activity alleviated the differentiation dysfunction caused by high glucose or overexpression of c-Myc.
此外,c-Myc 转录活性的抑制减轻了由高糖或 c-Myc 过表达引起的分化功能障碍。
此外,c-Myc 转录活性的抑制减轻了由高糖或 c-Myc 过表达引起的分化功能障碍。
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We examined the effects of nutraceuticals such as a flavonoid-rich extract of bergamot juice (BJe), alone or in association with curcumin (Cur) and resveratrol (Re), on mice testicular dysfunction caused by cadmium chloride (CdCl2).
我们研究了营养保健品(如富含类黄酮的佛手柑汁提取物 (BJe) 单独或与姜黄素 (Cur) 和白藜芦醇 (Re) 联合使用)对氯化镉 (CdCl2) 引起的小鼠睾丸功能障碍的影响。
我们研究了营养保健品(如富含类黄酮的佛手柑汁提取物 (BJe) 单独或与姜黄素 (Cur) 和白藜芦醇 (Re) 联合使用)对氯化镉 (CdCl2) 引起的小鼠睾丸功能障碍的影响。
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Attention hyperactivity disorder (ADHD) entails a detailed assessment, involving varied social agents, to understand the dynamic manifestation of different ages as well as the dysfunction caused by it.
注意多动障碍 (ADHD) 需要进行详细的评估,涉及不同的社会因素,以了解不同年龄的动态表现以及由此引起的功能障碍。
注意多动障碍 (ADHD) 需要进行详细的评估,涉及不同的社会因素,以了解不同年龄的动态表现以及由此引起的功能障碍。
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Our present study aimed to explore the role of small conductance Ca2+-activated potassium channel type2 in memory and learning dysfunction caused by exposing neonates to sevoflurane.
我们目前的研究旨在探讨小电导 Ca2+ 激活的 2 型钾通道在新生儿暴露于七氟醚引起的记忆和学习障碍中的作用。
我们目前的研究旨在探讨小电导 Ca2+ 激活的 2 型钾通道在新生儿暴露于七氟醚引起的记忆和学习障碍中的作用。
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We conclude that the proteasome dysfunction caused by the accumulation of N-glycoproteins, primarily NRF1, ubiquitinated by SCFFBS2 accounts for the pathogenesis resulting from NGLY1 deficiency.
我们得出结论,由 SCFFBS2 泛素化的 N-糖蛋白(主要是 NRF1)的积累引起的蛋白酶体功能障碍解释了 NGLY1 缺乏引起的发病机制。
我们得出结论,由 SCFFBS2 泛素化的 N-糖蛋白(主要是 NRF1)的积累引起的蛋白酶体功能障碍解释了 NGLY1 缺乏引起的发病机制。
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Although, early cognitive deficits have been associated with synaptic loss and dysfunction caused by amyloid-β peptides (Aβ), accumulating evidences support a role of astrocytes in AD.
尽管早期认知缺陷与淀粉样蛋白-β 肽 (Aβ) 引起的突触丧失和功能障碍有关,但越来越多的证据支持星形胶质细胞在 AD 中的作用。
尽管早期认知缺陷与淀粉样蛋白-β 肽 (Aβ) 引起的突触丧失和功能障碍有关,但越来越多的证据支持星形胶质细胞在 AD 中的作用。
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As research of cognitive dysfunction caused by inflammation due to chemotherapy treatment progresses, more opportunities emerge for therapeutic methods to improve the quality of life for long-term survivors.
随着对化疗引起的炎症引起的认知功能障碍研究的进展,出现了更多改善长期幸存者生活质量的治疗方法的机会。
随着对化疗引起的炎症引起的认知功能障碍研究的进展,出现了更多改善长期幸存者生活质量的治疗方法的机会。
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Thus, our data show that in Chinese children with non-glomerular renal dysfunction caused by renal hypodysplasia and cystic kidney diseases, the common causative genes vary with age and CKD stage at disease onset.
因此,我们的数据表明,在由肾发育不良和囊性肾病引起的非肾小球肾功能不全的中国儿童中,常见的致病基因随年龄和发病时的 CKD 分期而变化。
因此,我们的数据表明,在由肾发育不良和囊性肾病引起的非肾小球肾功能不全的中国儿童中,常见的致病基因随年龄和发病时的 CKD 分期而变化。
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CONCLUSIONS
Our study suggests that long-term fluoride exposure is associated with kidney function in adults, and urinary NAG is a sensitive and robust marker of kidney dysfunction caused by fluoride exposure, which could be considered for the identification of early kidney injury in endemic fluorosis areas.
结论
我们的研究表明,长期氟化物暴露与成人肾功能有关,尿 NAG 是氟化物暴露引起的肾功能不全的敏感而有力的标志物,可考虑用于识别地方性氟中毒地区的早期肾损伤。
结论 我们的研究表明,长期氟化物暴露与成人肾功能有关,尿 NAG 是氟化物暴露引起的肾功能不全的敏感而有力的标志物,可考虑用于识别地方性氟中毒地区的早期肾损伤。
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Sepsis is an organ dysfunction caused by dysregulation of immune response towards systemic infection with high incidence and mortality rate.
脓毒症是由于对全身感染的免疫反应失调引起的器官功能障碍,发病率和死亡率都很高。
脓毒症是由于对全身感染的免疫反应失调引起的器官功能障碍,发病率和死亡率都很高。
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We present a rare case of ureteral obstruction with allograft dysfunction caused by an inguinal hernia.
我们提出了一个罕见的由腹股沟疝引起的同种异体移植物功能障碍的输尿管梗阻病例。
我们提出了一个罕见的由腹股沟疝引起的同种异体移植物功能障碍的输尿管梗阻病例。
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The objective of this study was to investigate whether Notch signalling pathway was involved in neurogenesis impairment and long-term neurocognitive dysfunction caused by neonatal ketamine exposure.
本研究的目的是调查 Notch 信号通路是否与新生儿氯胺酮暴露引起的神经发生损伤和长期神经认知功能障碍有关。
本研究的目的是调查 Notch 信号通路是否与新生儿氯胺酮暴露引起的神经发生损伤和长期神经认知功能障碍有关。
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However, the role of melatonin on CMEC dysfunction caused by hyperglycemia and its molecular mechanisms underlying these effects has not been clarified.
然而,褪黑激素对高血糖引起的CMEC功能障碍的作用及其潜在的分子机制尚未阐明。
然而,褪黑激素对高血糖引起的CMEC功能障碍的作用及其潜在的分子机制尚未阐明。
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Thus, PBM/NAC treatment may prevent hearing dysfunction caused by NIHL.
因此,PBM/NAC 治疗可以预防由 NIHL 引起的听力障碍。
因此,PBM/NAC 治疗可以预防由 NIHL 引起的听力障碍。
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Background Myocardial dysfunction caused by sepsis (SIMD) leads to high mortality in critically ill patients.
背景 脓毒症 (SIMD) 引起的心肌功能障碍导致重症患者的高死亡率。
背景 脓毒症 (SIMD) 引起的心肌功能障碍导致重症患者的高死亡率。
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Results
The results demonstrated that pretreatment of HaCaT and HFF-1 cells with UPF ameliorated cellular senescence, ROS and mROS overproduction, and mitochondrial dysfunction caused by UV exposure.
结果
结果表明,用 UPF 预处理 HaCaT 和 HFF-1 细胞可改善细胞衰老、ROS 和 mROS 过度产生以及紫外线照射引起的线粒体功能障碍。
结果 结果表明,用 UPF 预处理 HaCaT 和 HFF-1 细胞可改善细胞衰老、ROS 和 mROS 过度产生以及紫外线照射引起的线粒体功能障碍。
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Purpose and background Previous studies have suggested that promoting endogenous neurogenesis has great significance for the recovery of cognitive dysfunction caused by cerebral ischemia (CI).
目的与背景 以往的研究表明,促进内源性神经发生对于脑缺血(CI)引起的认知功能障碍的恢复具有重要意义。
目的与背景 以往的研究表明,促进内源性神经发生对于脑缺血(CI)引起的认知功能障碍的恢复具有重要意义。
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We sought to explore whether CARD exerts any positive effects against hyperglycemia-induced testicular dysfunction caused by type 2 diabetes and aimed to identify its possible intracellular pathways.
我们试图探索 CARD 是否对 2 型糖尿病引起的高血糖诱导的睾丸功能障碍发挥任何积极作用,并旨在确定其可能的细胞内途径。
我们试图探索 CARD 是否对 2 型糖尿病引起的高血糖诱导的睾丸功能障碍发挥任何积极作用,并旨在确定其可能的细胞内途径。
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Sensory, social, and emotional deficits of subjects with ASD were reported to be caused by an imbalance between excitatory and inhibitory neurotransmission as well as GABAergic dysfunction caused by inadequate receptor function.
据报道,ASD 受试者的感觉、社交和情绪缺陷是由兴奋性和抑制性神经传递之间的不平衡以及受体功能不足引起的 GABA 能功能障碍引起的。
据报道,ASD 受试者的感觉、社交和情绪缺陷是由兴奋性和抑制性神经传递之间的不平衡以及受体功能不足引起的 GABA 能功能障碍引起的。
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Deviations from normal growth in response to drug treatment provide insights into the induced cellular dysfunction caused by pharmacotherapy.
对药物治疗的反应与正常生长的偏差提供了对药物治疗引起的诱导细胞功能障碍的见解。
对药物治疗的反应与正常生长的偏差提供了对药物治疗引起的诱导细胞功能障碍的见解。
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Whereas slmir172cCR loss-of-function caused only a slight greening of petals and stamens, hypomorphic and loss-of-function slmir172dCR alleles were associated with the conversion of petals and stamens to sepaloids, which were produced in excess.
虽然 slmir172cCR 功能丧失仅导致花瓣和雄蕊轻微变绿,但 slmir172dCR 等位基因亚型和功能丧失与花瓣和雄蕊向萼片的转化有关,后者产生过量。
虽然 slmir172cCR 功能丧失仅导致花瓣和雄蕊轻微变绿,但 slmir172dCR 等位基因亚型和功能丧失与花瓣和雄蕊向萼片的转化有关,后者产生过量。
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• Planned tracheo-bronchoscopy and tracheal
toilettes are recommended to prevent critical obstruction of the airway,
which can be fatal in patients with associated impairment of lung
function caused by SARS-CoV-2 infection.
• 计划的气管支气管镜检查和气管
建议使用洗手液以防止严重阻塞气道,
这对伴有肺损伤的患者可能是致命的
SARS-CoV-2 感染引起的功能。
• 计划的气管支气管镜检查和气管 建议使用洗手液以防止严重阻塞气道, 这对伴有肺损伤的患者可能是致命的 SARS-CoV-2 感染引起的功能。
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Conclusion Catechin and quercetin significantly assuaged cortical and hippocampal redox stress and attenuated neurochemical dysfunction caused by rotenone toxicity.
结论 儿茶素和槲皮素可显着缓解皮质和海马氧化还原应激,减轻鱼藤酮毒性引起的神经化学功能障碍。
结论 儿茶素和槲皮素可显着缓解皮质和海马氧化还原应激,减轻鱼藤酮毒性引起的神经化学功能障碍。
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Tissue loss or dysfunction caused by trauma or disease is a major medical problem that threatens human health and life.
由创伤或疾病引起的组织损失或功能障碍是威胁人类健康和生命的重大医学问题。
由创伤或疾病引起的组织损失或功能障碍是威胁人类健康和生命的重大医学问题。
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Background: Endothelial dysfunction caused by persistent hyperglycemia in diabetes is responsible for impaired angiogenesis in diabetic wounds.
背景:糖尿病持续高血糖引起的内皮功能障碍是糖尿病伤口血管生成受损的原因。
背景:糖尿病持续高血糖引起的内皮功能障碍是糖尿病伤口血管生成受损的原因。
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Western blotting confirmed that phosphorylated proteins including AMPK, ULK1, and TP53 (of the AMPK pathway) may contribute to testicular dysfunction caused by hypoxia.
蛋白质印迹证实磷酸化蛋白包括 AMPK、ULK1 和 TP53(AMPK 途径)可能导致缺氧引起的睾丸功能障碍。
蛋白质印迹证实磷酸化蛋白包括 AMPK、ULK1 和 TP53(AMPK 途径)可能导致缺氧引起的睾丸功能障碍。
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Although the severity of MR and HF in dogs with MMVD is being evaluated as similar to human cardiology, the veterinary cardiologists are more focused on the severity of cardiac remodeling and cardiac dysfunction caused by MR, because surgical restoration of defected mitral apparatus is rarely done in dogs.
尽管 MMVD 犬的 MR 和 HF 严重程度被评估为与人类心脏病学相似,但兽医心脏病专家更关注由 MR 引起的心脏重塑和心功能不全的严重程度,因为在小狗。
尽管 MMVD 犬的 MR 和 HF 严重程度被评估为与人类心脏病学相似,但兽医心脏病专家更关注由 MR 引起的心脏重塑和心功能不全的严重程度,因为在小狗。
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Both ME and EAF improved cognitive dysfunction caused by scopolamine in mice by reducing TBARS levels and brain AChE activity.
ME 和 EAF 均通过降低 TBARS 水平和脑 AChE 活性来改善由东莨菪碱引起的小鼠认知功能障碍。
ME 和 EAF 均通过降低 TBARS 水平和脑 AChE 活性来改善由东莨菪碱引起的小鼠认知功能障碍。
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The experiments find equally potent gain of function caused by the truncating mutations or a recurrent missense mutation associated with clinically milder ataxia and pancytopenia syndromes, demonstrating that diverse clinical manifestations can arise from mutations that appear cell-biologically equivalent.
实验发现,与临床较轻的共济失调和全血细胞减少综合征相关的截断突变或复发性错义突变引起的功能获得同样有效,这表明不同的临床表现可能源于细胞生物学上表现相同的突变。
实验发现,与临床较轻的共济失调和全血细胞减少综合征相关的截断突变或复发性错义突变引起的功能获得同样有效,这表明不同的临床表现可能源于细胞生物学上表现相同的突变。
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These findings demonstrated that loss of Nfe2l1 attenuates pancreatic β cells damage and dysfunction caused by STZ exposure, partially due to Nfe2l1 deficiency-induced metabolic switch to enhanced glycolysis.
这些发现表明,Nfe2l1 的缺失减轻了 STZ 暴露引起的胰腺 β 细胞损伤和功能障碍,部分原因是 Nfe2l1 缺乏诱导的代谢转变为增强的糖酵解。
这些发现表明,Nfe2l1 的缺失减轻了 STZ 暴露引起的胰腺 β 细胞损伤和功能障碍,部分原因是 Nfe2l1 缺乏诱导的代谢转变为增强的糖酵解。
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This cell type-selective NMDAR-hypofunction caused a specific deficit in a delayed-matching-to-position (DMTP) 5-choice-based operant WM task.
这种细胞类型选择性 NMDAR 功能减退导致延迟匹配到位置 (DMTP) 基于 5 选择的操作性 WM 任务中的特定缺陷。
这种细胞类型选择性 NMDAR 功能减退导致延迟匹配到位置 (DMTP) 基于 5 选择的操作性 WM 任务中的特定缺陷。