Epiphyseal Fusion(骨骺融合)研究综述
Epiphyseal Fusion 骨骺融合 - Objectives This cross-sectional study aims to examine the variation between stages of epiphyseal fusion at the distal end of radius, ulna, tibia, and fibula and its usefulness in the evaluation of age. [1] Demographic profiling of a population of sheep buried in toto in the Ptolemaic-Early Roman animal necropolis at Syene/Aswan (Upper Egypt) revealed significantly higher age estimates based on tooth eruption and wear than those based on epiphyseal fusion. [2] When GH excess has its onset after epiphyseal fusion at puberty, the overgrowth of soft tissue and bone results in acromegaly. [3] The present study evaluates observer agreement of epiphyseal fusion and dental development stages obtained on CT scans of a U. [4] BackgroundThe growth potential of pubertal short stature boys is limited by the effect of estrogen on epiphyseal fusion. [5] The current study aimed to determine if multivariable, single-indicator age-estimation models outperform single-variable age-estimation models throughout ontogeny using the three most common subadult age indicators: diaphyseal dimensions, epiphyseal fusion, and dental development. [6] Whereas age is determined on the basis of the degree in which bones have grown, for instance, dental eruption, epiphyseal fusion, tooth mineralization, and diaphyseal length. [7] Several studies have recommended the application of magnetic resonance imaging (MRI) and assessment of the stage of epiphyseal fusion in age estimation. [8] This chapter also includes observations on dental eruption, epiphyseal fusion, and cranial suture closure as well as summary data on dominance rank and a discussion of the importance of dominance rank in chimpanzee social life and life history. [9] Various studies have explored additional therapies to optimize growth including the use of lower hydrocortisone doses with the addition of anti-androgens and aromatase inhibitors to blunt the effect of sex steroids on bone advancement and epiphyseal fusion [8]. [10] OBJECTIVES The aim of this work is to study age, sex, and population variations in epiphyseal fusion and persistence of the epiphyseal line in the appendicular skeleton of two identified modern (19th-20th c. [11] Their main difference is the status of the epiphyseal growth plates at the time of the GH hypersecretion; gigantism occurs during childhood when growth plates are not yet fused, and acromegaly occurs after epiphyseal fusion. [12]目的 本横断面研究旨在检查桡骨、尺骨、胫骨和腓骨远端骨骺融合阶段之间的变化及其在年龄评估中的有用性。 [1] 在 Syene/Aswan（上埃及）的托勒密-早期罗马动物墓地中埋葬的绵羊种群的人口统计资料显示，基于牙齿萌出和磨损的年龄估计值明显高于基于骨骺融合的年龄估计值。 [2] 当青春期骨骺融合后出现GH过量时，软组织和骨骼的过度生长导致肢端肥大症。 [3] 本研究评估在 U 的 CT 扫描中获得的骨骺融合和牙齿发育阶段的观察者一致性。 [4] 背景青春期身材矮小男孩的生长潜力受限于雌激素对骨骺融合的影响。 [5] 目前的研究旨在使用三个最常见的亚成年年龄指标确定多变量、单指标年龄估计模型在整个个体发育过程中是否优于单变量年龄估计模型：骨干尺寸、骨骺融合和牙齿发育。 [6] 而年龄是根据骨骼生长的程度来确定的，例如，牙齿萌出、骨骺融合、牙齿矿化和骨干长度。 [7] 一些研究建议在年龄估计中应用磁共振成像 (MRI) 和骨骺融合阶段的评估。 [8] 本章还包括对牙齿萌出、骨骺融合和颅缝闭合的观察，以及优势等级的汇总数据以及对优势等级在黑猩猩社会生活和生活史中重要性的讨论。 [9] 各种研究已经探索了其他疗法来优化生长，包括使用较低剂量的氢化可的松并添加抗雄激素和芳香酶抑制剂来减弱性类固醇对骨骼发育和骨骺融合的影响 [8]。 [10] 目标 这项工作的目的是研究两个已确定的现代（19 至 20 世纪 [11] 它们的主要区别在于 GH 分泌过多时骨骺生长板的状态；巨人症发生在儿童时期，此时生长板尚未融合，而肢端肥大症发生在骨骺融合后。 [12]
Early Epiphyseal Fusion
Background Central precocious puberty (CPP) due to premature activation of GnRH secretion results in early epiphyseal fusion and to a significant compromise in the achieved final adult height. [1] Androgen excess also leads to advancement of bone age, leading to ultimate short stature due to early epiphyseal fusion. [2] The diagnosis, if delayed, can ensue early arthritis, early epiphyseal fusion, and growth abnormality. [3]背景 由于 GnRH 分泌的过早激活导致的中枢性性早熟 (CPP) 导致早期骨骺融合并显着降低达到的最终成年身高。 [1] 雄激素过多还会导致骨龄提前，由于早期骨骺融合导致最终身材矮小。 [2] 如果延迟诊断，可能会导致早期关节炎、早期骨骺融合和生长异常。 [3]