Electrospun Polyester(电纺涤纶)研究综述
Electrospun Polyester 电纺涤纶 - Overall, the gradiently-degraded EPI-loaded electrospun polyester scaffolds are potential ureteral stent tubes for the local inhibition of the recurrence of UTUC, where the continued release of EPI can prevent the subsequent proliferation of residual tumor cells, and the gradient degradation is consistent with the repair of the ureter. [1] These consist in conducting polymer nanoparticles, which release drug molecules by altering their interactions with polymer, and electrospun polyester microfibres that contain electroactive nanoparticles able to alter the porosity of the matrix through an electro-mechanical actuation mechanism. [2] The aim of this study was the paired in vivo mechanical assessment of biostable and fast degrading electrospun polyester-urethane scaffolds to isolate the effects of material degradation and tissue formation after implantation. [3] Hence, the cytostatic-loaded electrospun polyester nanofiber capsules displayed controlled drug release and degradation, along with satisfactory antitumor properties, indicating their great potential in local malignancy chemotherapy. [4] Hence, the electrospun polyester scaffolds are non-toxic and biocompatible with vascular smooth muscle cells, and find promising potential as scaffolds for vascular tissue engineering. [5]总体而言，梯度降解的EPI负载电纺聚酯支架是局部抑制UTUC复发的潜在输尿管支架管，其中EPI的持续释放可以阻止残余肿瘤细胞随后的增殖，梯度降解与输尿管的修复。 [1] 这些包括导电聚合物纳米颗粒，它通过改变药物分子与聚合物的相互作用来释放药物分子，以及含有电活性纳米颗粒的电纺聚酯微纤维，能够通过机电驱动机制改变基质的孔隙率。 [2] 本研究的目的是对生物稳定和快速降解的静电纺丝聚酯-聚氨酯支架进行配对的体内力学评估，以分离植入后材料降解和组织形成的影响。 [3] 因此，负载细胞抑制剂的静电纺丝聚酯纳米纤维胶囊表现出受控的药物释放和降解，以及令人满意的抗肿瘤特性，表明它们在局部恶性肿瘤化疗中的巨大潜力。 [4] 因此，静电纺丝聚酯支架无毒且与血管平滑肌细胞具有生物相容性，有望成为血管组织工程支架。 [5]
Loaded Electrospun Polyester 负载电纺涤纶
Overall, the gradiently-degraded EPI-loaded electrospun polyester scaffolds are potential ureteral stent tubes for the local inhibition of the recurrence of UTUC, where the continued release of EPI can prevent the subsequent proliferation of residual tumor cells, and the gradient degradation is consistent with the repair of the ureter. [1] Hence, the cytostatic-loaded electrospun polyester nanofiber capsules displayed controlled drug release and degradation, along with satisfactory antitumor properties, indicating their great potential in local malignancy chemotherapy. [2]总体而言，梯度降解的EPI负载电纺聚酯支架是局部抑制UTUC复发的潜在输尿管支架管，其中EPI的持续释放可以阻止残余肿瘤细胞随后的增殖，梯度降解与输尿管的修复。 [1] 因此，负载细胞抑制剂的静电纺丝聚酯纳米纤维胶囊表现出受控的药物释放和降解，以及令人满意的抗肿瘤特性，表明它们在局部恶性肿瘤化疗中的巨大潜力。 [2]
electrospun polyester scaffold 静电纺涤纶脚手架
Overall, the gradiently-degraded EPI-loaded electrospun polyester scaffolds are potential ureteral stent tubes for the local inhibition of the recurrence of UTUC, where the continued release of EPI can prevent the subsequent proliferation of residual tumor cells, and the gradient degradation is consistent with the repair of the ureter. [1] Hence, the electrospun polyester scaffolds are non-toxic and biocompatible with vascular smooth muscle cells, and find promising potential as scaffolds for vascular tissue engineering. [2]总体而言，梯度降解的EPI负载电纺聚酯支架是局部抑制UTUC复发的潜在输尿管支架管，其中EPI的持续释放可以阻止残余肿瘤细胞随后的增殖，梯度降解与输尿管的修复。 [1] 因此，静电纺丝聚酯支架无毒且与血管平滑肌细胞具有生物相容性，有望成为血管组织工程支架。 [2]