Dna Sensor
DNA传感器
学术写作例句词典
Discover more insights into Dna Sensor DNA传感器
Keywords frequently search together with Dna Sensor DNA传感器
Narrow sentence examples with built-in keyword filters
Dna Sensor sentence examples within innate immune response
In innate immune cells, AIM2 servers as a cytoplasmic double‐stranded DNA sensor, playing a crucial role in the initiation of the innate immune response as a component of the inflammasome.
在先天免疫细胞中，AIM2 充当细胞质双链 DNA 传感器，作为炎性体的组成部分，在启动先天免疫反应中发挥着至关重要的作用。
在先天免疫细胞中，AIM2 充当细胞质双链 DNA 传感器，作为炎性体的组成部分，在启动先天免疫反应中发挥着至关重要的作用。
Full Text
The classic mode of STING activation is through binding the cyclic dinucleotide 2'3'-cyclic GMP-AMP (cGAMP), produced by the DNA sensor cyclic GMP-AMP synthase (cGAS), which is important for the innate immune response to microbial infection and autoimmune disease.
STING 激活的经典模式是通过结合由 DNA 传感器环状 GMP-AMP 合酶 (cGAS) 产生的环状二核苷酸 2'3'-环状 GMP-AMP (cGAMP)，这对于微生物感染的先天免疫反应很重要和自身免疫性疾病。
STING 激活的经典模式是通过结合由 DNA 传感器环状 GMP-AMP 合酶 (cGAS) 产生的环状二核苷酸 2'3'-环状 GMP-AMP (cGAMP)，这对于微生物感染的先天免疫反应很重要和自身免疫性疾病。
Full Text
Dna Sensor sentence examples within glassy carbon electrode
An impedimetric DNA sensor is developed for the highly sensitive determination of doxorubicin; the signal is charge transfer resistance recorded by electrochemical impedance spectroscopy using a glassy carbon electrode modified by electropolymerized Neutral Red or polyaniline and polyelectrolyte complexes including DNA.
开发了一种阻抗式 DNA 传感器，用于高灵敏度测定多柔比星；信号是通过电化学阻抗谱记录的电荷转移电阻，使用由电聚合中性红或聚苯胺和包括 DNA 在内的聚电解质复合物修饰的玻璃碳电极。
开发了一种阻抗式 DNA 传感器，用于高灵敏度测定多柔比星；信号是通过电化学阻抗谱记录的电荷转移电阻，使用由电聚合中性红或聚苯胺和包括 DNA 在内的聚电解质复合物修饰的玻璃碳电极。
Full Text
DNA sensors were assembled by consecutive deposition of thiacalix[4]arenes bearing oligolactic fragments, poly(ethylene imine), and DNA onto the glassy carbon electrode.
DNA 传感器通过连续沉积带有寡乳酸片段、聚（乙烯亚胺）和 DNA 的硫代杯[4]芳烃到玻碳电极上来组装。
DNA 传感器通过连续沉积带有寡乳酸片段、聚（乙烯亚胺）和 DNA 的硫代杯[4]芳烃到玻碳电极上来组装。
Full Text
Dna Sensor sentence examples within interferon inducible protein
Here, we identify cyclic GMP-AMP synthase (cGAS) and interferon-inducible protein 16 (IFI16) as the major DNA sensors in human immortalized podocytes.
在这里，我们将环状 GMP-AMP 合酶 (cGAS) 和干扰素诱导蛋白 16 (IFI16) 确定为人类永生化足细胞中的主要 DNA 传感器。
在这里，我们将环状 GMP-AMP 合酶 (cGAS) 和干扰素诱导蛋白 16 (IFI16) 确定为人类永生化足细胞中的主要 DNA 传感器。
Full Text
γ-interferon-inducible protein-16 (IFI16), a key DNA sensor, triggers downstream STING-dependent type I interferon (IFN-I) production and antiviral immunity.
γ-干扰素诱导蛋白 16 (IFI16) 是一种关键的 DNA 传感器，可触发下游 STING 依赖性 I 型干扰素 (IFN-I) 的产生和抗病毒免疫。
γ-干扰素诱导蛋白 16 (IFI16) 是一种关键的 DNA 传感器，可触发下游 STING 依赖性 I 型干扰素 (IFN-I) 的产生和抗病毒免疫。
Full Text
Dna Sensor sentence examples within retinoic acid inducible
The innate immune system is the first line of host defense, and it is capable of resisting both exogenous pathogenic challenges and endogenous danger signals via different pattern recognition receptors (PRRs), including Toll-like receptors, retinoic acid-inducible gene-1 (RIG-1)-like receptors, cytosolic DNA sensors, as well as nucleotide-binding oligomerization domain (NOD)-like receptors.
先天免疫系统是宿主防御的第一道防线，它能够通过不同的模式识别受体 (PRR)，包括 Toll 样受体、视黄酸诱导基因-1 (RIG) 来抵抗外源性致病挑战和内源性危险信号。 -1) 样受体、胞质 DNA 传感器以及核苷酸结合寡聚化结构域 (NOD) 样受体。
先天免疫系统是宿主防御的第一道防线，它能够通过不同的模式识别受体 (PRR)，包括 Toll 样受体、视黄酸诱导基因-1 (RIG) 来抵抗外源性致病挑战和内源性危险信号。 -1) 样受体、胞质 DNA 传感器以及核苷酸结合寡聚化结构域 (NOD) 样受体。
Full Text
PRRs can be further classified based on their localization into Toll-like receptors (TLRs), C-type lectin receptors (CLR), retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs), NOD-like receptors (NLRs) and cytosolic DNA sensors (CDS).
PRR 可根据其定位进一步分类为 Toll 样受体 (TLR)、C 型凝集素受体 (CLR)、视黄酸诱导基因-I (RIG-I) 样受体 (RLR)、NOD 样受体(NLR) 和胞质 DNA 传感器 (CDS)。
PRR 可根据其定位进一步分类为 Toll 样受体 (TLR)、C 型凝集素受体 (CLR)、视黄酸诱导基因-I (RIG-I) 样受体 (RLR)、NOD 样受体(NLR) 和胞质 DNA 传感器 (CDS)。
Full Text
Dna Sensor sentence examples within Cytosolic Dna Sensor
Comparative transcriptomic analysis of infected macrophages reveals genes encoding inducers of Type I IFN responses, such as cytosolic DNA sensors, were relatively less expressed by macrophages infected with M.
受感染巨噬细胞的比较转录组学分析显示，编码 I 型 IFN 反应诱导剂的基因，例如细胞溶质 DNA 传感器，在感染 M 的巨噬细胞中表达相对较少。
受感染巨噬细胞的比较转录组学分析显示，编码 I 型 IFN 反应诱导剂的基因，例如细胞溶质 DNA 传感器，在感染 M 的巨噬细胞中表达相对较少。
Full Text
The cytosolic DNA sensor cyclic GMP-AMP (cGAMP) synthetase (cGAS) has emerged as a fundamental component fueling the anti-pathogen immunity.
细胞溶质 DNA 传感器环 GMP-AMP (cGAMP) 合成酶 (cGAS) 已成为促进抗病原体免疫的基本成分。
细胞溶质 DNA 传感器环 GMP-AMP (cGAMP) 合成酶 (cGAS) 已成为促进抗病原体免疫的基本成分。
Full Text
Dna Sensor sentence examples within Electrochemical Dna Sensor
The electrochemical DNA sensor developed made it possible to distinguish native and thermally and chemically damaged DNA by changes in the charge transfer resistance and capacitance.
开发的电化学 DNA 传感器可以通过电荷转移电阻和电容的变化来区分天然和热和化学损伤的 DNA。
开发的电化学 DNA 传感器可以通过电荷转移电阻和电容的变化来区分天然和热和化学损伤的 DNA。
Full Text
We describe in this report a development of label-free electrochemical DNA sensor based on a novel nanostructured electrode of multi-walled carbon nanotubes (MWCNTs)/ nano-flowers-like manganese dioxide (MnO2)/polyaniline nanowires (PANi NWs) nanocomposite.
我们在本报告中描述了基于多壁碳纳米管 (MWCNTs)/纳米花状二氧化锰 (MnO2)/聚苯胺纳米线 (PANi NWs) 纳米复合材料的新型纳米结构电极的无标记电化学 DNA 传感器的开发。
我们在本报告中描述了基于多壁碳纳米管 (MWCNTs)/纳米花状二氧化锰 (MnO2)/聚苯胺纳米线 (PANi NWs) 纳米复合材料的新型纳米结构电极的无标记电化学 DNA 传感器的开发。
Full Text
Dna Sensor sentence examples within Cytoplasmic Dna Sensor
Recently, STING as a cytoplasmic DNA sensor has been found to be related to the progress of ALI.
近期，发现 STING 作为一种细胞质 DNA 传感器与 ALI 的进展有关。
近期，发现 STING 作为一种细胞质 DNA 传感器与 ALI 的进展有关。
Full Text
Here, we show that the cellular proinflammatory response and senescence induced by CDT depend on the cytoplasmic DNA sensor cGAS through the recognition of micronuclei.
在这里，我们表明 CDT 诱导的细胞促炎反应和衰老依赖于细胞质 DNA 传感器 cGAS 通过识别微核。
在这里，我们表明 CDT 诱导的细胞促炎反应和衰老依赖于细胞质 DNA 传感器 cGAS 通过识别微核。
Full Text
Dna Sensor sentence examples within Intracellular Dna Sensor
3535 Background: The intracellular DNA sensor stimulator of interferon genes (STING) plays a vital role in anti-tumor immune responses by recognition of self-DNA from tumors and by-products of genomic instability.
3535 背景：干扰素基因的细胞内 DNA 传感器刺激物 (STING) 通过识别来自肿瘤的自身 DNA 和基因组不稳定性的副产物，在抗肿瘤免疫反应中发挥重要作用。
3535 背景：干扰素基因的细胞内 DNA 传感器刺激物 (STING) 通过识别来自肿瘤的自身 DNA 和基因组不稳定性的副产物，在抗肿瘤免疫反应中发挥重要作用。
Full Text
Background: It has been reported that mitochondrial DNA (mtDNA) is released into the cytosol by mitochondrial stress and induces pro-inflammatory cytokine production via inflammasome and intracellular DNA sensors.
背景：据报道，线粒体 DNA (mtDNA) 通过线粒体应激释放到细胞质中，并通过炎症小体和细胞内 DNA 传感器诱导促炎细胞因子的产生。
背景：据报道，线粒体 DNA (mtDNA) 通过线粒体应激释放到细胞质中，并通过炎症小体和细胞内 DNA 传感器诱导促炎细胞因子的产生。
Full Text
Dna Sensor sentence examples within Stranded Dna Sensor
In innate immune cells, AIM2 servers as a cytoplasmic double‐stranded DNA sensor, playing a crucial role in the initiation of the innate immune response as a component of the inflammasome.
在先天免疫细胞中，AIM2 充当细胞质双链 DNA 传感器，作为炎性体的组成部分，在启动先天免疫反应中发挥着至关重要的作用。
在先天免疫细胞中，AIM2 充当细胞质双链 DNA 传感器，作为炎性体的组成部分，在启动先天免疫反应中发挥着至关重要的作用。
Full Text
Here, we found that the single-stranded DNA sensor RPA recruits Bre1, the ubiquitin E3 ligase for H2Bub, to replication forks or DNA breaks to stimulate local H2Bub.
在这里，我们发现单链 DNA 传感器 RPA 招募 Bre1，即 H2Bub 的泛素 E3 连接酶，复制叉或 DNA 断裂以刺激局部 H2Bub。
在这里，我们发现单链 DNA 传感器 RPA 招募 Bre1，即 H2Bub 的泛素 E3 连接酶，复制叉或 DNA 断裂以刺激局部 H2Bub。
Full Text
Dna Sensor sentence examples within Key Dna Sensor
Cyclic GMP-AMP synthase (cGAS) is a key DNA sensor that detects aberrant cytosolic DNA arising from pathogen invasions or genotoxic stresses.
环状 GMP-AMP 合酶 (cGAS) 是一种关键的 DNA 传感器，可检测由病原体入侵或基因毒性应激引起的异常胞质 DNA。
环状 GMP-AMP 合酶 (cGAS) 是一种关键的 DNA 传感器，可检测由病原体入侵或基因毒性应激引起的异常胞质 DNA。
Full Text
The cyclic GMP-AMP (cGAMP) synthase (cGAS) is a key DNA sensor that initiates STING-dependent signaling to produce type I interferons through synthesizing the secondary messenger 2'3'-cGAMP.
环状 GMP-AMP (cGAMP) 合酶 (cGAS) 是一种关键的 DNA 传感器，它通过合成次级信使 2'3'-cGAMP 来启动依赖 STING 的信号传导以产生 I 型干扰素。
环状 GMP-AMP (cGAMP) 合酶 (cGAS) 是一种关键的 DNA 传感器，它通过合成次级信使 2'3'-cGAMP 来启动依赖 STING 的信号传导以产生 I 型干扰素。
Full Text
Dna Sensor sentence examples within Cellular Dna Sensor
Transfected DNA has been known to activate cellular DNA sensor(s) and innate immune responses, but the effects of such responses on transfected DNA are not fully understood.
已知转染的 DNA 可激活细胞 DNA 传感器和先天免疫反应，但此类反应对转染 DNA 的影响尚不完全清楚。
已知转染的 DNA 可激活细胞 DNA 传感器和先天免疫反应，但此类反应对转染 DNA 的影响尚不完全清楚。
Full Text
GP83 interacted with cellular DNA sensors guinea pig IFI16 and cGAS, indicating a role in the cGAS/STING pathway.
GP83 与细胞 DNA 传感器豚鼠 IFI16 和 cGAS 相互作用，表明在 cGAS/STING 通路中的作用。
GP83 与细胞 DNA 传感器豚鼠 IFI16 和 cGAS 相互作用，表明在 cGAS/STING 通路中的作用。
Full Text
Dna Sensor sentence examples within Nuclear Dna Sensor
We show the function and significance of both nuclear DNA sensors, the DDR and PML-NBs, and demonstrate for three human herpesviruses of the alpha-, beta- and gamma-subfamilies, HSV-1, HCMV and KSHV respectively, how viral tegument proteins antagonize these pathways.
我们展示了两种核 DNA 传感器 DDR 和 PML-NB 的功能和意义，并分别展示了 alpha、beta 和 gamma 亚科的三种人类疱疹病毒 HSV-1、HCMV 和 KSHV，病毒外皮蛋白如何对抗这些途径。
我们展示了两种核 DNA 传感器 DDR 和 PML-NB 的功能和意义，并分别展示了 alpha、beta 和 gamma 亚科的三种人类疱疹病毒 HSV-1、HCMV 和 KSHV，病毒外皮蛋白如何对抗这些途径。
Full Text
In a recent study published in Science, Cao and colleagues identified hnRNPA2B1 as a new nuclear DNA sensor that initiated type I interferon (IFN-I) production upon DNA virus infection and amplified IFN-I responses by directly enhancing STINGdependent cytosolic DNA sensing pathways.
在最近发表在《科学》杂志上的一项研究中，Cao 及其同事将 hnRNPA2B1 确定为一种新的核 DNA 传感器，它在 DNA 病毒感染时启动 I 型干扰素 (IFN-I) 的产生，并通过直接增强 STING 依赖性细胞溶质 DNA 传感途径来放大 IFN-I 反应。
在最近发表在《科学》杂志上的一项研究中，Cao 及其同事将 hnRNPA2B1 确定为一种新的核 DNA 传感器，它在 DNA 病毒感染时启动 I 型干扰素 (IFN-I) 的产生，并通过直接增强 STING 依赖性细胞溶质 DNA 传感途径来放大 IFN-I 反应。
Full Text
Dna Sensor sentence examples within Immune Dna Sensor
As a RNA virus, PRRSV is mainly sensed by innate immune RNA receptors, whereas the role of innate immune DNA sensors in the PRRSV infection has not been elucidated.
作为一种 RNA 病毒，PRRSV 主要由先天免疫 RNA 受体感知，而先天免疫 DNA 传感器在 PRRSV 感染中的作用尚未阐明。
作为一种 RNA 病毒，PRRSV 主要由先天免疫 RNA 受体感知，而先天免疫 DNA 传感器在 PRRSV 感染中的作用尚未阐明。
Full Text
One pathway under investigation is the innate immune DNA sensor cyclic GMP-AMP synthase (cGAS) and its downstream receptor stimulator of interferon genes (STING).
正在研究的一种途径是先天免疫 DNA 传感器环 GMP-AMP 合酶 (cGAS) 及其下游干扰素基因受体刺激物 (STING)。
正在研究的一种途径是先天免疫 DNA 传感器环 GMP-AMP 合酶 (cGAS) 及其下游干扰素基因受体刺激物 (STING)。
Full Text
Dna Sensor sentence examples within Impedimetric Dna Sensor
An impedimetric DNA sensor is developed for the highly sensitive determination of doxorubicin; the signal is charge transfer resistance recorded by electrochemical impedance spectroscopy using a glassy carbon electrode modified by electropolymerized Neutral Red or polyaniline and polyelectrolyte complexes including DNA.
开发了一种阻抗式 DNA 传感器，用于高灵敏度测定多柔比星；信号是通过电化学阻抗谱记录的电荷转移电阻，使用由电聚合中性红或聚苯胺和包括 DNA 在内的聚电解质复合物修饰的玻璃碳电极。
开发了一种阻抗式 DNA 传感器，用于高灵敏度测定多柔比星；信号是通过电化学阻抗谱记录的电荷转移电阻，使用由电聚合中性红或聚苯胺和包括 DNA 在内的聚电解质复合物修饰的玻璃碳电极。
Full Text
In this study, a specific impedimetric DNA sensor based on graphene/zirconia nanocomposite has been developed to serve as a simple and rapid method for epidermal growth factor receptor (EGFR) mutations testing, necessary to guide the treatment regime of tyrosine kinase inhibitors (TKIs) therapy.
在这项研究中，开发了一种基于石墨烯/氧化锆纳米复合材料的特异性阻抗 DNA 传感器，作为一种简单快速的表皮生长因子受体 (EGFR) 突变检测方法，对指导酪氨酸激酶抑制剂 (TKI) 的治疗方案很有必要。治疗。
在这项研究中，开发了一种基于石墨烯/氧化锆纳米复合材料的特异性阻抗 DNA 传感器，作为一种简单快速的表皮生长因子受体 (EGFR) 突变检测方法，对指导酪氨酸激酶抑制剂 (TKI) 的治疗方案很有必要。治疗。
Full Text
Dna Sensor sentence examples within Designed Dna Sensor
The designed DNA sensor displayed a linear response to concentrations of DNA adenine methyltransferase (Dam) MTase from 0.
设计的 DNA 传感器对从 0 开始的 DNA 腺嘌呤甲基转移酶 (Dam) MTase 浓度呈线性响应。
设计的 DNA 传感器对从 0 开始的 DNA 腺嘌呤甲基转移酶 (Dam) MTase 浓度呈线性响应。
Full Text
Here, we report a specific molecular recognition activation drug nanoplatform based on specially designed DNA sensor-capped doxorubicin (DOX)-loaded mesoporous silica nanoparticles (MSNs), designated as specific molecular recognition-activated nanoparticle (SMRAN).
在这里，我们报告了一种特定的分子识别激活药物纳米平台，该平台基于专门设计的 DNA 传感器封端的多柔比星 (DOX) 负载的介孔二氧化硅纳米颗粒 (MSN)，称为特定分子识别激活纳米颗粒 (SMRAN)。
在这里，我们报告了一种特定的分子识别激活药物纳米平台，该平台基于专门设计的 DNA 传感器封端的多柔比星 (DOX) 负载的介孔二氧化硅纳米颗粒 (MSN)，称为特定分子识别激活纳米颗粒 (SMRAN)。
Full Text
Dna Sensor sentence examples within Ultrasensitive Dna Sensor
Here, we construct a simple, one-pot and ultrasensitive DNA sensor via exonuclease III (Exo III)-assisted target recycling amplification (ERA) combined with 3D DNA walker cascade amplification.
Full Text
This ultrasensitive DNA sensor appears to have excellent potential for rapid detection and diagnosis of genetic diseases.
Full Text
Dna Sensor sentence examples within Developed Dna Sensor
Dna Sensor sentence examples within Proposed Dna Sensor
Dna Sensor sentence examples within Different Dna Sensor
Dna Sensor sentence examples within dna sensor cga
It has been shown that ionizing radiation can mediate antitumor immunity via the activation of the cytosolic DNA sensor cGAS/STING pathway.
已经表明，电离辐射可以通过激活细胞溶质 DNA 传感器 cGAS/STING 通路来介导抗肿瘤免疫。
已经表明，电离辐射可以通过激活细胞溶质 DNA 传感器 cGAS/STING 通路来介导抗肿瘤免疫。
Full Text
Here, we show that the cellular proinflammatory response and senescence induced by CDT depend on the cytoplasmic DNA sensor cGAS through the recognition of micronuclei.
在这里，我们表明 CDT 诱导的细胞促炎反应和衰老依赖于细胞质 DNA 传感器 cGAS 通过识别微核。
在这里，我们表明 CDT 诱导的细胞促炎反应和衰老依赖于细胞质 DNA 传感器 cGAS 通过识别微核。
Full Text
Dna Sensor sentence examples within dna sensor cyclic
The cytosolic DNA sensor cyclic GMP-AMP (cGAMP) synthetase (cGAS) has emerged as a fundamental component fueling the anti-pathogen immunity.
细胞溶质 DNA 传感器环 GMP-AMP (cGAMP) 合成酶 (cGAS) 已成为促进抗病原体免疫的基本成分。
细胞溶质 DNA 传感器环 GMP-AMP (cGAMP) 合成酶 (cGAS) 已成为促进抗病原体免疫的基本成分。
Full Text
The classic mode of STING activation is through binding the cyclic dinucleotide 2'3'-cyclic GMP-AMP (cGAMP), produced by the DNA sensor cyclic GMP-AMP synthase (cGAS), which is important for the innate immune response to microbial infection and autoimmune disease.
STING 激活的经典模式是通过结合由 DNA 传感器环状 GMP-AMP 合酶 (cGAS) 产生的环状二核苷酸 2'3'-环状 GMP-AMP (cGAMP)，这对于微生物感染的先天免疫反应很重要和自身免疫性疾病。
STING 激活的经典模式是通过结合由 DNA 传感器环状 GMP-AMP 合酶 (cGAS) 产生的环状二核苷酸 2'3'-环状 GMP-AMP (cGAMP)，这对于微生物感染的先天免疫反应很重要和自身免疫性疾病。
Full Text
Dna Sensor sentence examples within dna sensor sting
In the present study, we found that the level of the adaptor of DNA sensor STING in NK cells was significantly decreased in HBeAg-negative CHB patients, and it was positively associated with the degranulation ability of NK cells.
在本研究中，我们发现 HBeAg 阴性 CHB 患者 NK 细胞中 DNA 传感器 STING 接头的水平显着降低，并且与 NK 细胞的脱颗粒能力呈正相关。
在本研究中，我们发现 HBeAg 阴性 CHB 患者 NK 细胞中 DNA 传感器 STING 接头的水平显着降低，并且与 NK 细胞的脱颗粒能力呈正相关。
Full Text
Interestingly, when MUS81 was targeted, it increased the accumulation of cytosolic DNA induced by MK1775 treatment and activated the DNA sensor STING-mediated innate immunity in the gastric cancer cells.
有趣的是，当 MUS81 被靶向时，它增加了 MK1775 处理诱导的细胞溶质 DNA 的积累，并激活了胃癌细胞中 DNA 传感器 STING 介导的先天免疫。
有趣的是，当 MUS81 被靶向时，它增加了 MK1775 处理诱导的细胞溶质 DNA 的积累，并激活了胃癌细胞中 DNA 传感器 STING 介导的先天免疫。
Full Text
Dna Sensor sentence examples within dna sensor ifi16
We report that a cytosolic DNA sensor IFI16 is essential for the activation of programmed cell death pathways in IAV infected cells.
我们报告说，细胞溶质 DNA 传感器 IFI16 对于 IAV 感染细胞中程序性细胞死亡途径的激活至关重要。
我们报告说，细胞溶质 DNA 传感器 IFI16 对于 IAV 感染细胞中程序性细胞死亡途径的激活至关重要。
Full Text
Here, using IFI16 knockout cells and p204-deficient mice, we demonstrate that the DNA sensor IFI16 enhances IFN-I production to inhibit influenza A virus (IAV) replication.
在这里，我们使用 IFI16 敲除细胞和 p204 缺陷小鼠，证明 DNA 传感器 IFI16 增强了 IFN-I 的产生以抑制甲型流感病毒 (IAV) 复制。
在这里，我们使用 IFI16 敲除细胞和 p204 缺陷小鼠，证明 DNA 传感器 IFI16 增强了 IFN-I 的产生以抑制甲型流感病毒 (IAV) 复制。
Full Text
Dna Sensor sentence examples within dna sensor protein
We had previously reported that in addition to p53 inactivation, overexpression of the DNA sensor protein-absent in melanoma 2 (AIM2)-contributes to tumorigenesis of oral squamous cell carcinoma (OSCC).
我们之前曾报道，除了 p53 失活外，黑色素瘤 2 (AIM2) 中不存在的 DNA 传感器蛋白的过表达有助于口腔鳞状细胞癌 (OSCC) 的肿瘤发生。
我们之前曾报道，除了 p53 失活外，黑色素瘤 2 (AIM2) 中不存在的 DNA 传感器蛋白的过表达有助于口腔鳞状细胞癌 (OSCC) 的肿瘤发生。
Full Text
GFP-MxA condensates also included the DNA sensor protein cyclic GMP-AMP synthase (cGAS), another protein known to be associated with liquid-like condensates.
GFP-MxA 缩合物还包括 DNA 传感器蛋白环状 GMP-AMP 合酶 (cGAS)，这是另一种已知与液体状缩合物相关的蛋白质。
GFP-MxA 缩合物还包括 DNA 传感器蛋白环状 GMP-AMP 合酶 (cGAS)，这是另一种已知与液体状缩合物相关的蛋白质。
Full Text
Dna Sensor sentence examples within dna sensor molecule
Intracellular SA triggered inflammatory and type I IFN responses via intracellular dsDNA sensor molecules and MyD88 and STING signaling pathways.
细胞内 SA 通过细胞内 dsDNA 传感器分子和 MyD88 和 STING 信号通路触发炎症和 I 型 IFN 反应。
细胞内 SA 通过细胞内 dsDNA 传感器分子和 MyD88 和 STING 信号通路触发炎症和 I 型 IFN 反应。
Full Text
The genes of cytosolic dsDNA sensor molecules such as cyclic GMP-AMP synthase (cGAS) were upregulated 11.
nan
nan
Full Text
Dna Sensor sentence examples within dna sensor pathway
However, genetically engineered mouse models have revealed that high-iron diets or deletion of pancreatic GPX4 (a key repressor of ferroptosis) accelerate the development of mutant Kras-driven PDAC by activating the STING1/TMEM173-dependent DNA sensor pathway.
Full Text
ExoDNA modulates tumor immunity via paracrine interactions and activation of cytosolic DNA sensor pathways, for example, STING, cGAS, and so forth in specific immune cell subsets.
Full Text
Dna Sensor sentence examples within dna sensor activity
Distinct control mechanisms restrict innate DNA sensor activity on mitotic chromosomes Pathogen sensing in innate immunity relies on receptors that must be efficient and precise.
Full Text
Stimulator of Interferon Genes (STING) integrates DNA sensor activity and mediates downstream IFN signaling in infected cells.
Full Text
Dna Sensor sentence examples within dna sensor aim2
Transcriptionally activated endogenous retroviruses generate double-stranded DNA (dsDNA) that triggers an antiviral innate immune response, and knockdown of the cytosolic dsDNA sensor Aim2 in G9a knockout (G9acKO) mammary epithelium rescues mammary ductal invasion.
Full Text
These protocols have successfully been applied in our recent study to unveil new regulatory mechanisms for different inflammasomes including the DNA sensor AIM2 (Erttmann et al.
Full Text
Dna Sensor sentence examples within dna sensor achieved
Taking advantage of the above merits of split-type detection, the ECL DNA sensor achieved ideal low detection of 6.
Full Text
Compared to those conventional ligation-based DNA sensors, the proposed alDNA sensor achieved the one-step capture of both wild-type and mutant DNA, and the subsequent detection on one chip, which effectively decreased systematic errors from the uncertain differences on the interfacial structural and microenvironmental changes, improved the detection accuracy.
Full Text
Dna Sensor sentence examples within dna sensor developed
The electrochemical DNA sensor developed made it possible to distinguish native and thermally and chemically damaged DNA by changes in the charge transfer resistance and capacitance.
开发的电化学 DNA 传感器可以通过电荷转移电阻和电容的变化来区分天然和热和化学损伤的 DNA。
开发的电化学 DNA 传感器可以通过电荷转移电阻和电容的变化来区分天然和热和化学损伤的 DNA。
Full Text
We report an ultrasensitive nanohybrid electrochemical DNA sensor developed to detect the LipL32 gene of Leptospira interrogans that causes leptospirosis.
我们报告了一种超灵敏的纳米混合电化学 DNA 传感器，用于检测引起钩端螺旋体病的问号钩端螺旋体的 LipL32 基因。
我们报告了一种超灵敏的纳米混合电化学 DNA 传感器，用于检测引起钩端螺旋体病的问号钩端螺旋体的 LipL32 基因。
Full Text
Dna Sensor sentence examples within dna sensor trex1
We introduce two specific nucleic acid sensors—the DNA sensor TREX1 and the RNA sensor RIG-I—and discuss their functional roles in the vasculature.
我们介绍了两种特定的核酸传感器——DNA 传感器 TREX1 和 RNA 传感器 RIG-I——并讨论了它们在脉管系统中的功能作用。
我们介绍了两种特定的核酸传感器——DNA 传感器 TREX1 和 RNA 传感器 RIG-I——并讨论了它们在脉管系统中的功能作用。
Full Text