Dengue Di(登革热)研究综述
Dengue Di 登革热 - It is an epidemiological model that translates the dengue disease through a system of differential ordinary equations which takes in consideration the dynamics of the disease between human and mosquito populations. [1] Given the availability of data for the individual geo-location of surveillance-notified dengue cases, we conducted a cross-sectional study to model non-severe and severe dengue simultaneously, identifying the spatial patterns of dengue distribution, using individual and area level covariates within a hierarchical Bayesian model. [2] Dengue disease is the most common mosquito-borne viral diseases in the world, especially in Bandung, Indonesia. [3] Dengue disease is one of the worst infectious diseases that require a high level machine to develop good models in order to learn. [4] Dengue disease is caused by four distinct viruses, termed serotypes (DENV1–4). [5] Using UB-DNA aptamers specific to each serotype of dengue NS1 proteins (DEN-NS1), we developed our aptamer–antibody sandwich ELISA for dengue diagnostics. [6] Dengue diagnosis test of mean value of TLC (<4000 cells/cmm) from 2015 to 2018 were evaluated with a prevalence of dengue disease of 35. [7] Several studies have emphasized on the need for epidemiological and entomological surveillance to monitor trends in dengue distribution, seasonal patterns and circulating serotypes to guide dengue control activities with efforts currently being made to ensure early warning signals for timely detection of outbreaks. [8] Background: Varied clinical manifestations, complex pathogenesis, and different viral serotypes make it difficult to predict the course of dengue disease. [9] Although the dengue disease caused by dengue virus (DENV) is asymptomatic and self-limiting in most people with first infection, increased severe dengue symptoms may be observed in people with heterotypic secondary DENV infection. [10] Dengue diagnostics including molecular and serological testing were performed on an encephalitis patient who presented with both classical dengue and neurological clinical symptoms. [11] 76% of subjects have good and fair knowledge about dengue disease, respectively. [12] This approach confirmed 19 household transmissions and revealed that dengue disperses an average of 70 m per day between households in these communities. [13] Jeddah, a global commercial and major port-of-entry city, is bearing the brunt of dengue disease burden in Saudi Arabia. [14] The result showed that the knowledge related to the transmission factor and the proliferation of dengue disease was quite good (72. [15] Possible solutions include incorporating adult mosquito sampling into routine vector surveillance, the establishment of laboratory-based sentinel surveillance, integrated vector and dengue disease surveillance and climate-based early warning systems using available technologies like mobile apps. [16] Overall, our unbiased analysis reveals associations between cellular profiles and disease severity, opening opportunities to study immunopathology in dengue disease and the potential predictive value of these parameters. [17] The nonstructural glycoprotein 1 (NS1) has been identified as playing a key role in dengue disease severity. [18] Dengue disease has been known to the people of Indonesia since 1779. [19] Dengue virus is a significant public health threat worldwide; however, the pathogenesis of dengue disease remains poorly understood due to lack of appropriate small animal models. [20] Eleven pediatric febrile patients confirmed for dengue disease and presenting neurological signs were studied in the University Hospital of Neiva, Huila Province. [21] This thesis examined the association of virus level, pre-existing antibody level with the clinical and laboratory parameters of dengue disease. [22] Dengue diagnosis is largely dependent on clinical symptoms and routinely confirmed with laboratory detection of dengue virus in patient serum samples collected via phlebotomy. [23] We proposed a compartmental model of dengue disease by incorporating the standard incidence relation between susceptible vectors and infected humans to see the effect of manageable parameters of the model on the basic reproduction number. [24] The purpose of this activity is to provide explanations to students who are expected to become agents of change in their environment in eradicating this dengue disease. [25] Serotype-specific dengue virus circulation and dengue disease in Bangkok, Thailand from 1973 to 1999. [26] Dengue virus (DENV) infection causes a spectrum of dengue diseases that have unclear underlying mechanisms. [27] Nowadays, dengue diagnosis tests are performed in laboratories, mainly based on serological tests. [28] The Role of Lymphocyte and Monocyte Count as a Predictor for Plasma Leakage in the Early Phase of Dengue Infection Plasma leakage is a clinical entity that plays a role in dengue disease severity, making dengue as one of the infectious diseases with high morbidity. [29] The mechanism of dengue disease in this population is not fully understood. [30] Measurement(s) dengue disease • transmission of virus Technology Type(s) digital curation Factor Type(s) temporal interval • province department Sample Characteristic - Organism Homo sapiens • Dengue virus Sample Characteristic - Environment temperate Sample Characteristic - Location Santa Fe Province Machine-accessible metadata file describing the reported data: https://doi. [31] 025) with household waste management behavior Conclusion: Poor household waste management behavior has a relationship with age, education, occupation, income, history of dengue disease in one family, knowledge, infrastructure, access to information, family support and support from health workers for dengue cases in Sendangmulyo village. [32] Here, we provide an overview of the current knowledge about the role of sNS1 in the immunopathogenesis of dengue disease. [33] albopictus is an invasive mosquito with wide phenotypic plasticity to adapt to broad and new areas, it is highly efficient to transmit the DENV horizontally and vertically, it can participate in the inter-endemic transmission of the dengue disease, and it can spread zoonotic arboviruses across forest and urban settings. [34] These study findings help to explain the associations between high MEHP levels and the high global burden of dengue disease. [35] OBJECTIVES Dengue disease progression is often associated with thrombocytopenia resulting from viral-induced bone marrow suppression and immune-mediated peripheral platelet consumption. [36] Moreover, dengue disease is a major problem in Indonesia, especially in North Kalimantan. [37] About 51,433 adult dengue cases between 2014 and 2015 were assessed for outpatient and inpatient claims data in Taiwan's National Health Insurance Research Database for the 30 days after their dengue diagnosis. [38] Two-fifths part of the world is at risk, which can be affected by dengue disease. [39] We observed gross pathologies in the spleen and liver that are consistent with dengue disease, including hemorrhaging as well as transcriptional patterns suggesting that antiviral responses and tissue damage were induced. [40] albopictus is an invasive mosquito with wide phenotypic plasticity to adapt to broad and new areas, it is highly efficient to transmit the DENV horizontally and vertically, it can participate in the inter-endemic transmission of the dengue disease, and it can spread zoonotic arboviruses across forest and urban settings. [41] However, both factors concurrently coexist in time and space and can interact, affecting mosquito development and dengue disease transmission. [42] On the basis of results, we conclude that the fractional order model is more suitable than integer order equations to evaluate the transmission of dengue disease. [43] This survey aims to determine the knowledge, attitude, and practices (KAP) among physicians in dengue diagnosis and treatment. [44] Dengue disease is caused by four serotypes of the dengue virus: DEN-1, DEN-2, DEN-3, and DEN-4. [45] The Covid-19 and dengue diagnosis were performed using standard tests followed by hematological profiling which included neutrophil lymphocyte ratio (NLR), platelet count, Vitamin D3 assessment, SGOT, SGPT, and SPO2 concentration levels. [46] The inadvertent errors in the recurrence relations (DTM) of equations for dengue disease transmission including initial conditions have been removed. [47] Dengue disease is a viral infectious disease caused by DENV-1, DENV-2, DENV-3, and DENV-4. [48] Using UB-DNA aptamers that bind specifically to each serotype or sub-serotype dengue NS1 protein (DEN-NS1), we developed an ELISA format with an aptamer − antibody sandwich system for dengue diagnostics. [49] In this paper, we intend to study, implement and review the performance of various prediction techniques coupled with bioinformatics for the early prediction of Dengue disease. [50]它是一种流行病学模型，通过考虑人类和蚊子种群之间疾病动态的微分常方程系统来转换登革热疾病。 [1] 鉴于监测通知登革热病例的个体地理位置数据的可用性，我们进行了一项横断面研究，同时模拟非严重和严重登革热，确定登革热分布的空间模式，使用个体和区域水平的协变量分层贝叶斯模型。 [2] 登革热是世界上最常见的蚊媒病毒性疾病，尤其是在印度尼西亚的万隆。 [3] 登革热是最严重的传染病之一，需要高级机器开发好的模型才能学习。 [4] 登革热由四种不同的病毒引起，称为血清型 (DENV1-4)。 [5] 使用对每种登革热 NS1 蛋白 (DEN-NS1) 血清型特异的 UB-DNA 适体，我们开发了用于登革热诊断的适体-抗体夹心 ELISA。 [6] 对2015年至2018年TLC平均值（<4000个细胞/厘米）的登革热诊断试验进行了评估，登革热患病率为35。 [7] 几项研究强调需要进行流行病学和昆虫学监测，以监测登革热分布、季节模式和循环血清型的趋势，以指导登革热控制活动，目前正在努力确保及时发现爆发的预警信号。 [8] 背景：临床表现多样，发病机制复杂，病毒血清型不同，因此难以预测登革热病程。 [9] 尽管登革热病毒 (DENV) 引起的登革热病在大多数初次感染的人中是无症状的和自限性的，但在异型继发性 DENV 感染的人中可能会观察到更严重的登革热症状。 [10] 对一名同时出现经典登革热和神经系统临床症状的脑炎患者进行了包括分子和血清学检测在内的登革热诊断。 [11] 76% 的受试者分别对登革热病有良好和公平的了解。 [12] 这种方法证实了 19 个家庭的传播，并揭示登革热在这些社区的家庭之间平均每天传播 70 m。 [13] 吉达是一个全球商业和主要入境口岸城市，在沙特阿拉伯首当其冲承受登革热疾病的负担。 [14] 结果表明，有关传播因子和登革热扩散的知识相当丰富（72. [15] 可能的解决方案包括将成蚊采样纳入常规媒介监测、建立基于实验室的哨点监测、综合媒介和登革热疾病监测以及使用移动应用程序等可用技术的基于气候的早期预警系统。 [16] 总体而言，我们的无偏分析揭示了细胞谱与疾病严重程度之间的关联，为研究登革热疾病的免疫病理学以及这些参数的潜在预测价值提供了机会。 [17] 非结构性糖蛋白 1 (NS1) 已被确定为在登革热疾病严重程度中起关键作用。 [18] 自 1779 年以来，印度尼西亚人民就已经知道登革热病。 [19] 登革热病毒是世界范围内的重大公共卫生威胁；然而，由于缺乏适当的小动物模型，登革热的发病机制仍然知之甚少。 [20] 在威拉省内瓦大学医院对 11 名确诊为登革热并出现神经系统体征的小儿发热患者进行了研究。 [21] 本论文研究了病毒水平、预先存在的抗体水平与登革热的临床和实验室参数之间的关系。 [22] 登革热诊断在很大程度上取决于临床症状，并通过在通过放血采集的患者血清样本中实验室检测登革热病毒进行常规确认。 [23] 我们通过结合易感病媒和感染者之间的标准发病率关系，提出了一个登革热病区室模型，以观察模型的可管理参数对基本繁殖数的影响。 [24] 这项活动的目的是为那些有望成为改变其环境以根除这种登革热疾病的推动者的学生提供解释。 [25] 1973 年至 1999 年泰国曼谷的血清型特异性登革热病毒传播和登革热病。 [26] 登革热病毒 (DENV) 感染会导致一系列登革热疾病，其潜在机制尚不清楚。 [27] 如今，登革热诊断测试在实验室进行，主要基于血清学测试。 [28] 淋巴细胞和单核细胞计数作为登革热感染早期血浆渗漏预测因子的作用血浆渗漏是一种临床实体，在登革热疾病严重程度中发挥作用，使登革热成为高发病率的传染病之一。 [29] 该人群中登革热的发病机制尚不完全清楚。 [30] 测量登革热 • 病毒传播 技术类型 数字化管理 因子类型 时间间隔 • 省部门 样本特征 - 生物 智人 • 登革热病毒样本特征 - 温带环境 样本特征 - 地点 Santa Fe Province Machine-描述报告数据的可访问元数据文件：https://doi. [31] 025) 与生活垃圾管理行为 结论：不良的生活垃圾管理行为与年龄、教育、职业、收入、一个家庭的登革热病史、知识、基础设施、信息获取、家庭支持和卫生工作者的支持有关Sendangmulyo村的登革热病例。 [32] 在这里，我们概述了当前关于 sNS1 在登革热免疫发病机制中的作用的知识。 [33] 白纹蚊是一种具有广泛表型可塑性的入侵性蚊子，适应广阔和新的领域，对DENV的水平和垂直传播效率很高，可以参与登革热的跨地方传播，可以将人畜共患虫媒病毒传播到各地。森林和城市环境。 [34] 这些研究结果有助于解释高 MEHP 水平与高全球登革热疾病负担之间的关联。 [35] 目标 登革热疾病进展通常与病毒诱导的骨髓抑制和免疫介导的外周血小板消耗导致的血小板减少症有关。 [36] 此外，登革热是印度尼西亚的一个主要问题，尤其是在北加里曼丹。 [37] 台湾国民健康保险研究数据库对 2014 年至 2015 年间约 51,433 例成人登革热病例进行了登革热诊断后 30 天的门诊和住院索赔数据评估。 [38] 世界五分之二的地区处于危险之中，可能受到登革热的影响。 [39] 我们观察到脾脏和肝脏中与登革热病一致的总体病理学，包括出血以及表明诱导抗病毒反应和组织损伤的转录模式。 [40] 白纹蚊是一种具有广泛表型可塑性的入侵性蚊子，适应广阔和新的领域，对DENV的水平和垂直传播效率很高，可以参与登革热的跨地方传播，可以将人畜共患虫媒病毒传播到各地。森林和城市环境。 [41] 然而，这两种因素在时间和空间上同时并存，可以相互作用，影响蚊子的发育和登革热的传播。 [42] 根据结果，我们得出结论，分数阶模型比整数阶方程更适合评估登革热的传播。 [43] 本次调查旨在确定医生在登革热诊断和治疗方面的知识、态度和实践（KAP）。 [44] 登革热是由登革热病毒的四种血清型引起的：DEN-1、DEN-2、DEN-3 和 DEN-4。 [45] Covid-19 和登革热诊断使用标准测试进行，然后进行血液学分析，包括中性粒细胞淋巴细胞比率 (NLR)、血小板计数、维生素 D3 评估、SGOT、SGPT 和 SPO2 浓度水平。 [46] 已消除包括初始条件在内的登革热传播方程的递归关系 (DTM) 中的无意错误。 [47] 登革热是由 DENV-1、DENV-2、DENV-3 和 DENV-4 引起的病毒性传染病。 [48] 使用与每种血清型或亚血清型登革热 NS1 蛋白 (DEN-NS1) 特异性结合的 UB-DNA 适体，我们开发了一种带有适体 - 抗体夹心系统的 ELISA 格式，用于登革热诊断。 [49] 在本文中，我们打算研究、实施和审查各种预测技术与生物信息学相结合用于登革热疾病早期预测的性能。 [50]
untuk mengetahui hubungan
Tujuan penelitian untuk mengetahui hubungan tindakan keluarga dengan pencegahan demam berdarah dengue di Puskesmas Parsikkaman. [1] Penelitian ini bertujuan untuk mengetahui hubungan cuaca mikro dengan prevalensi penyakit demam berdarah dengue di Kabupaten Bone tahun 2013-2015. [2] Tujuan penelitian ini adalah untuk mengetahui hubungan perilaku PSN Plus dengan kejadian Demam Berdarah Dengue di wilayah Puskesmas Basuki Rahmat Kota Bengkulu. [3]该研究的目的是确定 Parsikkaman 健康中心的家庭行为与预防登革出血热之间的关系。 [1] 本研究旨在确定微天气与 2013-2015 年 Bone Regency 登革出血热流行之间的关系。 [2] 本研究的目的是确定 PSN Plus 行为与明古鲁市 Basuki Rahmat 健康中心的登革出血热发病率之间的关系。 [3]
mild dengue fever 轻度登革热
Usually, the primary infection is asymptomatic or causes mild dengue fever (DF), while secondary infections with a different serotype increase the risk of severe dengue disease (dengue hemorrhagic fever, DHF). [1] Dengue virus (DENV) is an emerging infectious pathogen transmitted by mosquitoes that causes mild dengue fever and progressive severe dengue diseases. [2] Based on the clinical hallmarks, the different severities of patients range from mild dengue fever (MDF) to severe dengue diseases (SDDs) and include dengue hemorrhagic fever or dengue shock syndrome. [3]通常，原发感染无症状或引起轻度登革热 (DF)，而不同血清型的继发感染会增加严重登革热（登革出血热，DHF）的风险。 [1] 登革热病毒 (DENV) 是一种由蚊子传播的新兴传染性病原体，可导致轻度登革热和进行性严重登革热疾病。 [2] nan [3]
dengue hemorrhagic fever 登革出血热
About 20% of infected patients shows a spectrum of clinical manifestation, ranging from a mild flu-like syndrome, to dengue fever, to life-threatening severe dengue diseases, including dengue hemorrhagic fever and dengue shock syndrome. [1] One of the efforts in controlling Dengue Hemorrhagic Fever (DHF) is to break the chain of transmission by controlling the vector through the eradication of Dengue Hemorrhagic Fever Mosquito Nest, which is an activity to eradicate eggs, larvae and cocoons of Aedes aegypti infectious dengue disease. [2]大约 20% 的感染患者表现出一系列临床表现，从轻度流感样综合征到登革热，再到危及生命的严重登革热疾病，包括登革出血热和登革休克综合征。 [1] 控制登革出血热 (DHF) 的努力之一是通过根除登革出血热蚊巢来控制媒介来打破传播链，这是一项消灭埃及伊蚊传染性登革热病的卵、幼虫和茧的活动. [2]
Berdarah Dengue Di 登革热
Jumlah kasus Demam Berdarah Dengue di Indonesia terdapat 4 propinsi yang sangat tinggi yaitu, Jawa Timur (340 kasus), Jawa Barat (270 kasus), Jawa Tengah (213 kasus) dan Kalimantan Timur (103 kasus). [1] Kader jumantik adalah kelompok kerja kegiatan pemberantasan penyakit demam berdarah dengue di tingkat desa dalam wadah lembaga ketahanan masyarakat desa. [2] AbstrakTujuan penelitian ini adalah untuk melihat sebaran kasus Demam Berdarah Dengue di Provinsi Jawa Tengah, menganalisa pola sebaran kasus DBD, mengestimasi pengelompokan dan mengidentifikasi lokasi dengan kasuskasus DBD yang tinggi dengan memperhitungkan faktor spasial. [3] Demam Berdarah Dengue disebabkan oleh virus dengue, ditularkan oleh vektor nyamuk Aedes aegypti dan Aedes albopictus. [4] Jumlah kasus demam berdarah dengue di Kota Bandung tidak hanya menagalami peningkatan tetapi juga menyebabkan beberapa kematian. [5] Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan dan sikap keluarga tentang pemberantasan sarang nyamuk demam berdarah dengue di wilayah kerja UPTD Puskesmas Cigasong Kabupaten Majalengka Tahun 2018. [6] Peningkatan kasus Deman Berdarah Dengue di Kabupaten Sidenreng Rappang dengan angka morbiditas 384 kasus dan angka mortalitas 5 kasus. [7] Penyebaran Populasi Nyamuk Aedes aegypti s ebagai Vektor Penyakit Demam Berdarah Dengue di Kota Tidore Kepulauan ( D i stribution of Aedes aegypti Mosquito Population as A Vector of D engue Fever Disease in Tidore Kepulauan City) Fahrisa l 1* ) , Betsy Pinaria 1 ) , Dantje Tarore 1 ) 1) Program Studi Entomologi, Pasca Sarjana Universitas Sam Ratulangi, Manado 95115 * Email korespondensi : atreyafahrisal@gmail. [8] Tindakan pencegahan penyakit Demam Berdarah Dengue dilakukan dengan pengendalian terhadap vektor melalui pemberantasan jentik nyamuk Aedes aegypti yang dapat dikombinasikan dengan perilaku menguras, menutup dan mengubur (3M) sehingga akan menjadi lebih efektif dalam mencegah penyakit DBD. [9] Tujuan penelitian untuk mengetahui hubungan tindakan keluarga dengan pencegahan demam berdarah dengue di Puskesmas Parsikkaman. [10] Latar Belakang demam Berdarah Dengue disebabkan oleh salah satu dari empat antigen yang berbeda, tetapi sangat dekat satu dengan yang lain. [11] Penelitian ini bertujuan untuk mengetahui hubungan cuaca mikro dengan prevalensi penyakit demam berdarah dengue di Kabupaten Bone tahun 2013-2015. [12] Tujuan penelitian ini untuk mengetahui Pengaruh Kawat Kasa Pada Ventilasi Dan Pelaksanaan PSN DBD Terhadap Kejadian Demam Berdarah Dengue di Wilayah Kerja Puskesmas Kebayakan Kabupaten Aceh Tengah Tahun 2017. [13] Latarbelakang : Pengasapan insektisida ( fogging ) merupakan salah satu upaya dalam menanggulangi wabah Demam Berdarah Dengue di masyarakat, namun fogging merupakan upaya penanggulangan yang hanya bersifat sementara. [14] Tujuan penelitian ini adalah untuk mengetahui hubungan perilaku PSN Plus dengan kejadian Demam Berdarah Dengue di wilayah Puskesmas Basuki Rahmat Kota Bengkulu. [15] Hasil: Ada hubungan antara ventilasi dengan p value (p=0,039) dan nilai (OR=0,072, CI= 0,006-0,849), Tidak ada hubungan antara kelembaban dengan nilai p value (p=0,642) dan nilai (OR=0,347,CI= 0,036-3,367) dan Ada Hubungan antara pencahayaan dengan nilai p value (p=0,039) dan nilai (OR=0,072, CI=0,006-0,849) dengan kejadian demam Berdarah dengue di wilayah kerja Puskesmas Kalasan Kabupaten Sleman. [16] Tujuan: Mengetahui gambaran hasil analisis spasial berdasarkan kasus kejadian, faktor risiko lingkungan pada kasus Demam Berdarah Dengue di wilayah kerja Puskesmas Sungai Durian Kabupaten Kubu Raya tahun 2016 - Juli 2018. [17] Penelitian ini bertujuan untuk membuat model forecasting peningkatan jumlah kasus Demam Berdarah Dengue menggunakan algoritma regresi linear dan melakukan analisis pengaruh dari temperatur, kelembapan dan curah hujan dalam kanaikan kasus penyakit Demam Berdarah Dengue di Provinsi DKI Jakarta dari model regresi yang dibuat. [18] Kota Palopo merupakan salah satu daerah endemis demam berdarah Dengue di Provinsi Sulawesi Selatan. [19] Terdapat hubungan yang bermakna antara pengetahuan (p=0,000) dan sikap (p=0,003) dengan perilaku keluarga tentang pemberantasan sarang nyamuk demam berdarah dengue di korong Sarang Gagak. [20]印尼登革出血热病例数很高的4个省分别是东爪哇（340例）、西爪哇（270例）、中爪哇（213例）和东加里曼丹（103例）。 [1] jumantik 干部是村社区抗灾机构内的村一级根除登革出血热工作组。 [2] nan [3] nan [4] 万隆市的登革出血热病例数不仅增加，还造成数人死亡。 [5] nan [6] nan [7] 埃及伊蚊种群作为登革热病媒介的分布在蒂多尔群岛市) Fahrisa l 1*)、Betsy Pinaria 1)、Dantje Tarore 1) 1) 昆虫学研究项目，萨姆拉图兰吉大学研究生，万鸦老 95115 * 电子邮件通信： atreyafahrisal@gmail。 [8] 登革出血热的预防措施是通过消灭埃及伊蚊幼虫来控制媒介，并结合引流、关闭和掩埋（3M）行为，从而更有效地预防DHF疾病。 [9] 该研究的目的是确定 Parsikkaman 健康中心的家庭行为与预防登革出血热之间的关系。 [10] nan [11] 本研究旨在确定微天气与 2013-2015 年 Bone Regency 登革出血热流行之间的关系。 [12] 本研究的目的是在 2017 年亚齐中央摄政区 Kebayak 公共卫生中心确定金属丝纱布对通风和 PSN DHF 实施对登革出血热发病率的影响。 [13] nan [14] 本研究的目的是确定 PSN Plus 行为与明古鲁市 Basuki Rahmat 健康中心的登革出血热发病率之间的关系。 [15] nan [16] nan [17] 本研究旨在使用线性回归算法创建登革出血热病例增加的预测模型，并分析温度、湿度和降雨对 DKI 雅加达省登革出血热病例增加的影响。建立的回归模型。 [18] 帕洛波市是南苏拉威西省登革出血热流行区之一。 [19] nan [20]