Cartilage Model(软骨模型)研究综述
Cartilage Model 软骨模型 - This is usually based on computed tomography (CT) for bone models, on magnetic resonance imaging (MRI) for cartilage models. [1] Three-dimensional bone and cartilage models were created by double echo steady state (DESS) morphological magnetic resonance image (MRI) segmentation, and the models were semi-manually registered with multi-slice, multi-echo (MSME) T2 MRI. [2] By coregistering the cartilage models generated from the images, which were obtained before and after the activity, the residual strains at discrete locations on the cartilage surfaces immediately after the activity was determined. [3] Our findings highlight the importance of locally, and thus heterogeneously, approaching pore compaction for load bearing in cartilage models, while emphasising that such effects can be represented by simple constitutive relations. [4]这通常基于用于骨骼模型的计算机断层扫描 (CT)，基于用于软骨模型的磁共振成像 (MRI)。 [1] 通过双回波稳态 (DESS) 形态磁共振图像 (MRI) 分割创建三维骨骼和软骨模型，并通过多层多回波 (MSME) T2 MRI 半手动配准模型。 [2] 通过对从活动前后获得的图像生成的软骨模型进行配准，确定活动后立即在软骨表面上离散位置处的残余应变。 [3] 我们的研究结果强调了局部的重要性，因此在软骨模型中，在承重方面接近孔隙压实，同时强调这种影响可以用简单的本构关系来表示。 [4]
Vivo Cartilage Model 体内软骨模型
Raman measurements were performed on a series of ex vivo cartilage models: 1) chemically GAG-depleted bovine cartilage explants (n=40), 2) mechanically abraded bovine cartilage explants (n=30), 3) aging human cartilage explants (n=14), and 4) anatomical-site-varied ovine osteochondral explants (n=6). [1] Raman measurements were performed on a series of ex vivo cartilage models: 1) chemically GAG-depleted bovine cartilage explants (n=40), 2) mechanically abraded bovine cartilage explants (n=30), 3) aging human cartilage explants (n=14), and 4) anatomical-site-varied ovine osteochondral explants (n=6). [2] Ex vivo cartilage models offer the potential to study disease processes but are surprisingly rarely used. [3] Ex vivo cartilage models allow 1) profiling of chondrocyte mediated alterations of cartilage tissue turnover, 2) visualizing the cartilage ECM composition, and 3) chondrocyte rearrangement directly in the tissue. [4]对一系列离体软骨模型进行拉曼测量：1) 化学去除 GAG 的牛软骨外植体 (n=40)，2) 机械磨损的牛软骨外植体 (n=30)，3) 老化的人软骨外植体 (n= 14) 和 4) 解剖部位不同的绵羊骨软骨外植体 (n=6)。 [1] 对一系列离体软骨模型进行拉曼测量：1) 化学去除 GAG 的牛软骨外植体 (n=40)，2) 机械磨损的牛软骨外植体 (n=30)，3) 老化的人软骨外植体 (n= 14) 和 4) 解剖部位不同的绵羊骨软骨外植体 (n=6)。 [2] 离体软骨模型提供了研究疾病过程的潜力，但令人惊讶的是很少使用。 [3] 离体软骨模型允许 1) 分析软骨细胞介导的软骨组织周转变化，2) 可视化软骨 ECM 组成，以及 3) 直接在组织中的软骨细胞重排。 [4]
Articular Cartilage Model
Moreover, the reparative capacity of scaffolds was discerned after implantation in the full-thickness articular cartilage model in rabbits for up to 12 weeks. [1] Second, a synovial fluid pressure (SFP) articular cartilage model was created in Abaqus based on our previous study, where the exudation of the interstitial fluid from articular cartilage was regulated depending on the pressure difference between the interior and exterior of the cartilage. [2]此外，在植入兔全层关节软骨模型长达12周后，观察到支架的修复能力。 [1] 其次，基于我们之前的研究，在 Abaqus 中创建了滑液压力 (SFP) 关节软骨模型，其中关节软骨间质液的渗出是根据软骨内部和外部之间的压力差来调节的。 [2]