Introduction to Versus Inhaled

Data was collected using a pDR-1500 monitor and analysed to capture concentration variations, spatial variability, exposure doses, commuting costs versus inhaled doses, health burden and economic losses.

Objective To compare the mean change in peak expiratory flow values in children receiving inhaled beclomethasone dipropionate versus inhaled budesonide in the treatment of mild persistent asthma.

OBJECTIVE This study compared the effectiveness of leukotriene receptor antagonists (LTRAs) versus inhaled corticosteroids (ICSs) in elderly patients with asthma in real-world settings.

Assuming a 1:9 ratio for edible versus inhaled exposures, we calculated that a sample size of 2000 would provide enough data to reliably estimate a 5-fold increased rate of ED visits for edible versus inhaled exposure.

Methods: We leveraged in silico, in vitro, and in vivo tools preclinically and found significant differences in lung to plasma partition ratio when iJAK-001 was given intravenously (IV) or intratracheally in a solution-based formulation versus that in suspension, as well as pharmacodynamic response in preclinical asthma models when delivered systemically via IV infusion versus inhaled.

Background and objective Retrospective claims data in patients with chronic obstructive pulmonary disease (COPD) initiating maintenance therapy with inhaled fixed-dose combinations of long-acting muscarinic antagonist/long-acting β2-agonist (LAMA/LABA) versus inhaled corticosteroid (ICS)/LABA have not been reported.