South African
南非的
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South African sentence examples within higher education institution
Methods To help the research community to understand nursing students' perceptions towards the use of virtual reality as a possible alternative to high-fidelity simulation and to determine whether students would enjoy virtual clinical simulation, undergraduate nursing students for a South African higher education institution were asked to partake in a virtual clinical simulation where they could manage a patient with a foreign object in the airway.
方法 為了幫助研究界了解護生對使用虛擬現實作為高保真模擬的可能替代方案的看法,並確定學生是否會喜歡虛擬臨床模擬,我們詢問了南非高等教育機構的本科護生參與虛擬臨床模擬,他們可以管理氣道中有異物的患者。
方法 為了幫助研究界了解護生對使用虛擬現實作為高保真模擬的可能替代方案的看法,並確定學生是否會喜歡虛擬臨床模擬,我們詢問了南非高等教育機構的本科護生參與虛擬臨床模擬,他們可以管理氣道中有異物的患者。
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We collected data from three South African higher education institutions (HEI) offering emergency medical care qualifications.
我們從提供緊急醫療護理資格的三所南非高等教育機構 (HEI) 收集數據。
我們從提供緊急醫療護理資格的三所南非高等教育機構 (HEI) 收集數據。
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South African sentence examples within cross sectional study
APOE genetic variation is understudied in African populations; hence, this cross-sectional study in a rural South African community examined allele and genotype frequencies, and their associations with cognitive function.
APOE 遺傳變異在非洲人群中的研究不足;因此,這項在南非農村社區進行的橫斷面研究檢查了等位基因和基因型頻率,以及它們與認知功能的關聯。
APOE 遺傳變異在非洲人群中的研究不足;因此,這項在南非農村社區進行的橫斷面研究檢查了等位基因和基因型頻率,以及它們與認知功能的關聯。
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This is a cross-sectional study of 43 black South African women (age 20–35 years) with obesity (BMI 30–40 kg/m2) and without type 2 diabetes that measured the following: DI, insulin sensitivity (SI), acute insulin response (AIRg), insulin secretion rate (ISR), hepatic insulin extraction and peripheral insulin clearance (frequently sampled i.
這是一項對 43 名患有肥胖症(BMI 30-40 kg/m2)且沒有 2 型糖尿病的南非黑人女性(年齡 20-35 歲)進行的橫斷面研究,測量以下指標:DI、胰島素敏感性 (SI)、急性胰島素反應 (AIRg)、胰島素分泌率 (ISR)、肝臟胰島素提取和外周胰島素清除率(經常採樣 i.
這是一項對 43 名患有肥胖症(BMI 30-40 kg/m2)且沒有 2 型糖尿病的南非黑人女性(年齡 20-35 歲)進行的橫斷面研究,測量以下指標:DI、胰島素敏感性 (SI)、急性胰島素反應 (AIRg)、胰島素分泌率 (ISR)、肝臟胰島素提取和外周胰島素清除率(經常採樣 i.
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South African sentence examples within receptor binding domain
Here, we report the generation and use of a recombinant (r)SARS-CoV-2 USA/WA1/2020 (WA-1) strain expressing Venus and an rSARS-CoV-2 strain expressing mCherry and containing mutations K417N, E484K, and N501Y found in the receptor binding domain (RBD) of the spike (S) glycoprotein of the South African (SA) B.
在這裡,我們報告了表達 Venus 的重組 (r)SARS-CoV-2 USA/WA1/2020 (WA-1) 菌株和表達 mCherry 並含有突變 K417N、E484K 和N501Y 存在於南非 (SA) B 的刺突 (S) 糖蛋白的受體結合結構域 (RBD)。
在這裡,我們報告了表達 Venus 的重組 (r)SARS-CoV-2 USA/WA1/2020 (WA-1) 菌株和表達 mCherry 並含有突變 K417N、E484K 和N501Y 存在於南非 (SA) B 的刺突 (S) 糖蛋白的受體結合結構域 (RBD)。
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The severity of the COVID-19 pandemic necessitated the search for drugs against the causative viral agent, SARS-CoV-2 Among the promising targets is the viral surface of SARS-CoV-2 adorned by spike proteins appearing as crown-like structures known for their function in viral attachment and entry mechanisms To exploit the potential of previously reported antiviral microbial metabolites, we explored the antagonistic prospects of myxobacterial secondary metabolites against receptor-binding domains (RBD) to host cell receptors namely angiotensin-converting enzyme 2 (ACE2), basigin (CD147) and glucose-regulated protein 78 (GRP78) as well as the binding site of neuropilin-1 (NRP1) in the SARS-CoV-2 spike protein using in silico molecular interaction based approaches such as molecular and protein-protein docking along with an investigation of their pharmacokinetic profiles Thus, the cyclic depsipeptide chondramides in general conferred high affinity and demonstrated strong binding to true viral hot spots in the spike protein such as Arg403, Gln493 and Gln498 with high selectivity compared to most of the host cell receptors studied The binding energy (BE) of chondramide C3 (1), being the top ligand against ACE2 and CD147 RBD, remained relatively constant when docked against most of the spike variants such as A475V, L452R, V483A, S477N, F490L and V439K On the other hand, the parent congener chondramide C (2) exhibited strong affinity against the UK variant (N501Y), the South African variant (E484K) and the globally prevalent D614G along with its co-occurring mutation in the RBD, I472V Meanwhile, chondramide C6 (29) showed highest BE towards GRP78 RBD To study the effect of complexed chondramide ligands, protein-protein binding experiments were carried out using high-ambiguity driven docking (HADDOCK) which showed weaker binding affinity between spike and the target host receptors The in silico active chondramides in general conferred favourable pharmacokinetic properties illustrating their potential to be developed as anti-COVID-19 drugs that limit viral attachment and minimize infection.
COVID-19 大流行的嚴重性需要尋找針對致病病毒病原體 SARS-CoV-2 的藥物,其中有希望的目標是 SARS-CoV-2 的病毒表面,表面上裝飾有呈冠狀結構的刺突蛋白,已知它們在病毒附著和進入機制中的作用 為了利用先前報導的抗病毒微生物代謝物的潛力,我們探索了粘桿菌次級代謝物對受體結合域 (RBD) 對宿主細胞受體即血管緊張素轉換酶 2 (ACE2) 的拮抗前景, basigin (CD147) 和葡萄糖調節蛋白 78 (GRP78) 以及 SARS-CoV-2 刺突蛋白中神經纖維蛋白 1 (NRP1) 的結合位點,使用基於計算機分子相互作用的方法,例如分子和蛋白質-蛋白質對接以及對其藥代動力學特徵的研究因此,環狀縮肽軟骨酰胺通常具有高親和力並顯示出與真正的病毒的強結合與所研究的大多數宿主細胞受體相比,刺突蛋白中的所有熱點如 Arg403、Gln493 和 Gln498 具有高選擇性 軟骨胺 C3 (1) 的結合能 (BE) 是針對 ACE2 和 CD147 RBD 的頂級配體,保持不變當與大多數尖峰變體(例如 A475V、L452R、V483A、S477N、F490L 和 V439K)對接時相對恆定另一方面,親本同源軟骨酰胺 C (2) 對英國變體 (N501Y)、南非變體 (E484K) 和全球流行的 D614G 及其在 RBD 中的共同突變 I472V 同時,軟骨酰胺 C6 (29) 對 GRP78 RBD 表現出最高的 BE 為了研究複合軟骨酰胺配體的作用,進行了蛋白質-蛋白質結合實驗使用高模糊度驅動對接 (HADDOCK) 顯示刺突和目標宿主受體之間的結合親和力較弱表明它們有可能被開發為限制病毒附著和減少感染的抗 COVID-19 藥物。
COVID-19 大流行的嚴重性需要尋找針對致病病毒病原體 SARS-CoV-2 的藥物,其中有希望的目標是 SARS-CoV-2 的病毒表面,表面上裝飾有呈冠狀結構的刺突蛋白,已知它們在病毒附著和進入機制中的作用 為了利用先前報導的抗病毒微生物代謝物的潛力,我們探索了粘桿菌次級代謝物對受體結合域 (RBD) 對宿主細胞受體即血管緊張素轉換酶 2 (ACE2) 的拮抗前景, basigin (CD147) 和葡萄糖調節蛋白 78 (GRP78) 以及 SARS-CoV-2 刺突蛋白中神經纖維蛋白 1 (NRP1) 的結合位點,使用基於計算機分子相互作用的方法,例如分子和蛋白質-蛋白質對接以及對其藥代動力學特徵的研究因此,環狀縮肽軟骨酰胺通常具有高親和力並顯示出與真正的病毒的強結合與所研究的大多數宿主細胞受體相比,刺突蛋白中的所有熱點如 Arg403、Gln493 和 Gln498 具有高選擇性 軟骨胺 C3 (1) 的結合能 (BE) 是針對 ACE2 和 CD147 RBD 的頂級配體,保持不變當與大多數尖峰變體(例如 A475V、L452R、V483A、S477N、F490L 和 V439K)對接時相對恆定另一方面,親本同源軟骨酰胺 C (2) 對英國變體 (N501Y)、南非變體 (E484K) 和全球流行的 D614G 及其在 RBD 中的共同突變 I472V 同時,軟骨酰胺 C6 (29) 對 GRP78 RBD 表現出最高的 BE 為了研究複合軟骨酰胺配體的作用,進行了蛋白質-蛋白質結合實驗使用高模糊度驅動對接 (HADDOCK) 顯示刺突和目標宿主受體之間的結合親和力較弱表明它們有可能被開發為限制病毒附著和減少感染的抗 COVID-19 藥物。
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South African sentence examples within higher education sector
Such differences can be linked to the differentiated nature of the South African higher education sector, where the capacity of institutions to deal with Covid‑19 related challenges and to respond comprehensively to the needs of different groups of international students varies in accordance with the availability of relevant structures, systems, digital platforms and other resources.
這種差異可能與南非高等教育部門的差異化性質有關,其中機構應對 Covid-19 相關挑戰和全面響應不同國際學生群體需求的能力因提供的相關結構、系統、數字平台和其他資源。
這種差異可能與南非高等教育部門的差異化性質有關,其中機構應對 Covid-19 相關挑戰和全面響應不同國際學生群體需求的能力因提供的相關結構、系統、數字平台和其他資源。
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Exploring reflective practices and their contribution to the emerging of transformed practices and identities in the South African higher education sector would be a fruitful avenue of future research.
探索反思性實踐及其對南非高等教育部門轉變實踐和身份認同的貢獻將是未來研究的一條富有成果的途徑。
探索反思性實踐及其對南非高等教育部門轉變實踐和身份認同的貢獻將是未來研究的一條富有成果的途徑。
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South African sentence examples within coronavirus disease 2019
The coronavirus disease 2019 (COVID-19) has hugely affected not only South Africans but also people globally.
2019 年冠狀病毒病 (COVID-19) 不僅嚴重影響了南非人,也影響了全球人民。
2019 年冠狀病毒病 (COVID-19) 不僅嚴重影響了南非人,也影響了全球人民。
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At 04∶50 on January 1, 2021, a 36-year-old Chinese project manager (Case A), a 29-year-old Chinese worker (Case B), and a 53-year-old Chinese businessman (Case C) returned from Africa (Case A and B from South Africa and Case C from Lesotho) on the same flight and tested coronavirus disease 2019 (COVID-19) RNA positive by real-time polymerase chain reaction (PCR) by Baoan District People’s Hospital Shenzhen CDC received their oral nasopharyngeal swabs packages from the hospital and retested COVID-19 RNA positive at 09∶50 Meanwhile, Case D, a close contact of Case A, was transferred to the designated hotel for centralized isolation for 14 days His oral nasopharyngeal swabs were collected and sent for the detection of COVID-19 RNA as routine surveillance testing on the 1, 4, 7, 14 days of quarantine;these were reported back as COVID-19 RNA positive at 22∶50 on January 4, 2021 and at 05∶30 on January 5, 2021 by Shenzhen CDC The four cases were transferred respectively by negative pressure ambulances to the Third People’s Hospital of Shenzhen for further treatment within five hours of COVID-19 infection confirmation by Shenzhen CDC On admission, chest CT images showed no abnormalities among all cases Epidemiological investigation revealed that the 4 cases had COVID-19 RNA negative test results before departure and self-reportedly had effective protection by wearing medical protective masks (Case A wore a disposable medical mask, while Case B, C, and D wore N95 masks) and protective suits (Case B) during the flight In addition, they reported no history of fever, fatigue, or respiratory symptoms within 14 days prior to their diagnosis However, according to the report of Case A, he was possibly exposed on his return business trip from Cape Town to Johannesburg in South Africa from December 16 to December 30, 2020, when he visited and had dinner with colleagues and had a meal in a fast food restaurant Case B had a history of performing work-related tasks, staying at the dormitory with workmates His roommate, who took the same flight from South Africa to China, was diagnosed as an asymptomatic carrier of COVID-19 on January 1, 2021 in Shenzhen Case C’s potential exposure might have been a 4-hour-trip in a vehicle from his company in Lesotho to an airport hotel with a local resident without effective protection Case D’s potential exposure was the experience that he took nucleic acid testing in South Africa and shuttle bus from workplace to the airport with Case A before boarding Using the results of the epidemiological investigation, clinical symptoms, and laboratory results, these patients were diagnosed as asymptomatic patients with COVID-19 in coordination with clinicians and experts The specimens of the 4 asymptomatic patients’ were sequenced by Illumina MiSeq Sequencing platform between January 2 to January 5, 2021 On January 4 and January 7, 3 whole genome sequences and 1 were obtained, respectively Compared with the Wuhan reference sequence (EPI_ISL_402119) (1–2), these 4 newly identified Shenzhen strains showed 29 nucleotide variation sites, which contained the single nucleotide polymorphisms (SNPs) that defined lineage B 1 351 (20H/501Y V2 branch) (3) A maximum of 29 genomic variation sites were detected in the 4 high-quality genomic sequences (for Cases A–D, number of genomic variation sites were 29, 19, 25, and 25, respectively, including G160A, G174T, C241T, C281T, C1059T, C3037T, G5230T, C8660T, C8964T, A10323G, G11230T, T13324A, C14408T, C14925T, T16062C, G19656T, A21801C, G22299T, G22813T, G23012A, A23063T, A23403G, C23664T, T25084C, G25563T, C25904T, C26456T, C28647T, C28887T;sequence coverage ranged from 91 4% to 99 2%) A major difference between the nucleotide sequences of A/D and B/C were detected in the position of 1174 (A1174C for A/D and A1174T for B/C) By online comparison of the assembled sequence with the published COVID-19 database, we obtained the phylogenetic relationship tree (Figure 1) of the virus strains The 4 COVID-19 samples of imported African cases were lineage B 1 351 (20H/501Y V2) variant strains (homology of 99 99% to 100%), which had been circulating in South Africa since October 2020 (4) The cladogram showed that the genome sequences of the 4 cases imported from Africa (Case A–D) all contained the characteristic mutation sites (the mutations of the spike protein D80A, K417N, E484K, N501Y, D614G, and A701V) of the South African variant strain B 1 351 The major differences between the A/D and B/C when comparing their amino acid sequences were as follows: L18F was detected in Case C;D215G was detected in Case B/C;R246I was detected in Case A;but data on the same position was missing in Case D These B 1 351 variants strains were imported early to China and might exert a great threat to the prevention and control of COVID-19 in China Systematically tracking higher risk international variants is therefore important as it allows monitoring of the new variants nationally and internationally.
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South African sentence examples within structural equation modelling
The study tests theoretical model and presents findings by analysing data (partial least squares structural equation modelling method) gathered from 151 South African firms.
該研究通過分析從 151 家南非公司收集的數據(偏最小二乘結構方程建模方法)測試了理論模型並展示了結果。
該研究通過分析從 151 家南非公司收集的數據(偏最小二乘結構方程建模方法)測試了理論模型並展示了結果。
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Data were collected from 487 South African consumers using a structured questionnaire and were analysed using structural equation modelling.
使用結構化問卷從 487 名南非消費者收集數據,並使用結構方程模型進行分析。
使用結構化問卷從 487 名南非消費者收集數據,並使用結構方程模型進行分析。
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South African sentence examples within intimate partner violence
Despite this, many forms of oppression, including domestic or intimate partner violence and sex- and gender-based violence, continue to plague South African universities and society in general.
儘管如此,許多形式的壓迫,包括家庭暴力或親密伴侶暴力以及基於性和性別的暴力,繼續困擾著南非的大學和整個社會。
儘管如此,許多形式的壓迫,包括家庭暴力或親密伴侶暴力以及基於性和性別的暴力,繼續困擾著南非的大學和整個社會。
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While some studies have examined gender-based violence in South Africa, particularly in the form of physical abuse or intimate partner violence, no previous work has simply asked Black married women how they make sense of coercive sexual experiences, or even rape, nor inquired why they continue to tolerate these experiences despite the rights and dignity guaranteed by the South African Constitution.
雖然一些研究調查了南非的基於性別的暴力,特別是身體虐待或親密伴侶暴力的形式,但以前沒有任何工作簡單地詢問黑人已婚婦女如何理解強迫性經歷甚至強姦,也沒有詢問原因儘管南非憲法保障了權利和尊嚴,但他們繼續容忍這些經歷。
雖然一些研究調查了南非的基於性別的暴力,特別是身體虐待或親密伴侶暴力的形式,但以前沒有任何工作簡單地詢問黑人已婚婦女如何理解強迫性經歷甚至強姦,也沒有詢問原因儘管南非憲法保障了權利和尊嚴,但他們繼續容忍這些經歷。
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South African sentence examples within higher education context
Research and praxis in the field teaching and learning in the South African higher education context has been characterised by calls to expand the languages of teaching and learning through the inclusive use of African languages in higher education.
南非高等教育領域教學和學習領域的研究和實踐的特點是呼籲通過在高等教育中全面使用非洲語言來擴展教學語言。
南非高等教育領域教學和學習領域的研究和實踐的特點是呼籲通過在高等教育中全面使用非洲語言來擴展教學語言。
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We argue that Ubuntu pedagogy provides an alternation to the current pedagogies that draw from European theories for teaching and learning in the South African higher education context.
我們認為,Ubuntu 教學法提供了一種替代當前教學法的方法,該教學法借鑒了歐洲在南非高等教育背景下的教學和學習理論。
我們認為,Ubuntu 教學法提供了一種替代當前教學法的方法,該教學法借鑒了歐洲在南非高等教育背景下的教學和學習理論。
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South African sentence examples within authorities reported variant
South African sentence examples within qualitative case study
Setting: The qualitative case study was conducted at two Urban ECCE centers in Durban, KwaZulu Natal Province, South African.
設置:定性案例研究在南非誇祖魯納塔爾省德班的兩個城市 ECCE 中心進行。
設置:定性案例研究在南非誇祖魯納塔爾省德班的兩個城市 ECCE 中心進行。
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Setting: This qualitative case study was conducted in the FP department of a teacher-training institution at a South African university.
設置:這個定性案例研究是在南非大學的一個教師培訓機構的 FP 部門進行的。
設置:這個定性案例研究是在南非大學的一個教師培訓機構的 FP 部門進行的。
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South African sentence examples within year old female
On February 19, 2021, a 48-year-old male (Case A, XG2275) returning from Nigeria and a 38-year-old female (Case B, XG2276) returning from Ukraine via airplane were tested by the laboratory of Guangzhou Customs using nose swabs to test for coronavirus disease 2019 (COVID-19) Both of them tested positive and were transported by ambulance from the isolation point to Guangzhou Eighth People’s Hospital They are still undergoing centralized medical observation in the hospital after recovery On March 5, Guangdong CDC received the samples and began virus isolation and genome sequencing analysis On March 10, the 2 samples were sequenced using Nanopore GridION On March 12, the sequencing analysis concluded that the 2 virus genomes belonged to lineage B 1 525, a new COVID-19 variant first emerging in Nigeria, which was first detected by genome sequencing in mid-December in Nigeria but was also quickly found in cases in the United Kingdom, France, and elsewhere As of March 8, 2021, a total of 577 counted sequences in 30 countries were found in the world (1) Compared with the Wuhan reference sequence (EPI_ISL_402119) (2–3), the strain from Case A (XG2275) displayed 24 nucleotide variation sites (C241T, C1498T, A1807G, G2659A, C3037T, C6285T, T8593C, C9565T, C14407T, C14408T, C18171T, A20724G, A21717G, C21762T, G23012A, A23403G, G23593C, T24224C, C24748T, T26767C, C28308G, A28699G, C28887T, and G29543T) including the single nucleotide polymorphisms (SNPs) that defined the L-lineage European branch and belonged to the Pangolin lineage B 1 525 (Figure 1) Furthermore, 10 amino acid mutation sites (E:L21X, M:I82T, N:A12G, N:T205I, S:Q52R, S:A67V, S:E484K, S:D614G, S:Q677H, and S:F888L) and 3 amino acid deletions (H69del, V70del, and Y144del) were detected in the protein that corresponded to the features of the Nigerian variant (B 1 525) (4) Compared with the Wuhan reference sequence (EPI_ISL_402119) (2–3), the Case B (XG2276) strain displayed 22 nucleotide variation sites (C241T, C1498T, A1807G, C3037T, C6285T, T8593C, C9565T, C14407T, C14408T, C18171T, A20724G, C21762T, G23012A, A23403G, G23593C, T24224C, C24748T, T26767C, C28308G, A28699G, C28887T, and G29543T) including the SNPs that defined the L-lineage European branch and belonged to the Pangolin lineage B 1 525 (Figure 1) Furthermore, 9 amino acid mutation sites (E:L21X, M:I82T, N:A12G, N:T205I, S:A67V, S:E484K, S:D614G, S:Q677H, and S:F888L) and 3 amino acid deletions (H69del, V70del, and Y144del) were detected in the protein that corresponded to the features of the Nigerian variant (B 1 525) The variant first emerging in Nigeria (B 1 525) shares the same 3 amino acid deletions (H69del, V70del, and Y144del) with the 501Y V1 variant (also known as the B 1 1 7) The mutation E484K is also present in the 501Y V2 variant first emerging in South Africa (also known as the B 1 351) and Brazilian strains (501Y V3) The amino acid substitution at position 677 (Q677H) is identical to that found in variants recently described in the United States The amino acid substitutions Q52R and A67V are unique to the B 1 525 (4) This is the third recent detection of a major international variant following the detection of the United Kingdom 501Y V1 variant and the South African 501Y V2 variant The transmissibility and pathogenicity of these mutant variants urgently needs further study (5–6).
2021年2月19日,一名從尼日利亞返回的48歲男性(病例A,XG2275)和一名從烏克蘭乘飛機返回的38歲女性(病例B,XG2276)經廣州海關實驗室檢測鼻拭子檢測2019冠狀病毒病(COVID-19) 兩人檢測呈陽性,由救護車從隔離點運送至廣州市第八人民醫院 康復後仍在醫院接受集中醫學觀察 3月5日,廣東省疾控中心收到樣本並開始病毒分離和基因組測序分析 3 月 10 日,使用 Nanopore GridION 對 2 個樣本進行測序 3 月 12 日,測序分析得出結論,這 2 個病毒基因組屬於 B 1 525 譜系,首先是一種新的 COVID-19 變體在尼日利亞出現,12 月中旬在尼日利亞首次通過基因組測序檢測到,但在英國、法國和其他地方也迅速發現了病例,截至 2021 年 3 月 8 日,共有 577在全球發現了 30 個國家的計數序列 (1) 與武漢參考序列 (EPI_ISL_402119) (2-3) 相比,來自案例 A 的菌株 (XG2275) 顯示出 24 個核苷酸變異位點 (C241T、C1498T、A1807G、G2659A、 C3037T, C6285T, T8593C, C9565T, C14407T, C14408T, C18171T, A20724G, A21717G, C21762T, G23012A, A23403G, G23593C, T24224C, C24748T, T26767C, C28308G, A28699G, C28887T, and G29543T) including the single nucleotide polymorphisms (SNPs) that定義了 L 譜系歐洲分支,屬於穿山甲譜系 B 1 525(圖 1)此外,10 個氨基酸突變位點(E:L21X、M:I82T、N:A12G、N:T205I、S:Q52R、S:在蛋白質中檢測到與尼日利亞變體(B 1 525 )(4)與武漢參考序列(EPI_ISL_402119)(2-3)相比,案例B(XG2276)菌株顯示22個核苷酸變異位點(C241T,C14 98T, A1807G, C3037T, C6285T, T8593C, C9565T, C14407T, C14408T, C18171T, A20724G, C21762T, G23012A, A23403G, G23593C, T24224C, C24748T, T26767C, C28308G, A28699G, C28887T, and G29543T) including the SNPs that defined the L - 血統歐洲分支,屬於穿山甲血統 B 1 525 (圖 1) 此外,9 個氨基酸突變位點 (E:L21X, M:I82T, N:A12G, N:T205I, S:A67V, S:E484K, S :D614G、S:Q677H 和 S:F888L) 和 3 個氨基酸缺失 (H69del、V70del 和 Y144del) 在與尼日利亞變體 (B 1 525) 的特徵相對應的蛋白質中檢測到(B 1 525) 與 501Y V1 變體(也稱為 B 1 1 7)共享相同的 3 個氨基酸缺失(H69del、V70del 和 Y144del) 突變 E484K 也存在於首次出現在南方的 501Y V2 變體中非洲(也稱為 B 1 351)和巴西菌株 (501Y V3) 第 677 位的氨基酸替換 (Q677H) 與最近發現的變體相同在美國抄寫 氨基酸替換 Q52R 和 A67V 是 B 1 525 獨有的 (4) 這是繼英國 501Y V1 變體和南非 501Y V2 變體之後,最近第三次檢測到主要國際變體這些突變變體的傳播性和致病性迫切需要進一步研究(5-6)。
2021年2月19日,一名從尼日利亞返回的48歲男性(病例A,XG2275)和一名從烏克蘭乘飛機返回的38歲女性(病例B,XG2276)經廣州海關實驗室檢測鼻拭子檢測2019冠狀病毒病(COVID-19) 兩人檢測呈陽性,由救護車從隔離點運送至廣州市第八人民醫院 康復後仍在醫院接受集中醫學觀察 3月5日,廣東省疾控中心收到樣本並開始病毒分離和基因組測序分析 3 月 10 日,使用 Nanopore GridION 對 2 個樣本進行測序 3 月 12 日,測序分析得出結論,這 2 個病毒基因組屬於 B 1 525 譜系,首先是一種新的 COVID-19 變體在尼日利亞出現,12 月中旬在尼日利亞首次通過基因組測序檢測到,但在英國、法國和其他地方也迅速發現了病例,截至 2021 年 3 月 8 日,共有 577在全球發現了 30 個國家的計數序列 (1) 與武漢參考序列 (EPI_ISL_402119) (2-3) 相比,來自案例 A 的菌株 (XG2275) 顯示出 24 個核苷酸變異位點 (C241T、C1498T、A1807G、G2659A、 C3037T, C6285T, T8593C, C9565T, C14407T, C14408T, C18171T, A20724G, A21717G, C21762T, G23012A, A23403G, G23593C, T24224C, C24748T, T26767C, C28308G, A28699G, C28887T, and G29543T) including the single nucleotide polymorphisms (SNPs) that定義了 L 譜系歐洲分支,屬於穿山甲譜系 B 1 525(圖 1)此外,10 個氨基酸突變位點(E:L21X、M:I82T、N:A12G、N:T205I、S:Q52R、S:在蛋白質中檢測到與尼日利亞變體(B 1 525 )(4)與武漢參考序列(EPI_ISL_402119)(2-3)相比,案例B(XG2276)菌株顯示22個核苷酸變異位點(C241T,C14 98T, A1807G, C3037T, C6285T, T8593C, C9565T, C14407T, C14408T, C18171T, A20724G, C21762T, G23012A, A23403G, G23593C, T24224C, C24748T, T26767C, C28308G, A28699G, C28887T, and G29543T) including the SNPs that defined the L - 血統歐洲分支,屬於穿山甲血統 B 1 525 (圖 1) 此外,9 個氨基酸突變位點 (E:L21X, M:I82T, N:A12G, N:T205I, S:A67V, S:E484K, S :D614G、S:Q677H 和 S:F888L) 和 3 個氨基酸缺失 (H69del、V70del 和 Y144del) 在與尼日利亞變體 (B 1 525) 的特徵相對應的蛋白質中檢測到(B 1 525) 與 501Y V1 變體(也稱為 B 1 1 7)共享相同的 3 個氨基酸缺失(H69del、V70del 和 Y144del) 突變 E484K 也存在於首次出現在南方的 501Y V2 變體中非洲(也稱為 B 1 351)和巴西菌株 (501Y V3) 第 677 位的氨基酸替換 (Q677H) 與最近發現的變體相同在美國抄寫 氨基酸替換 Q52R 和 A67V 是 B 1 525 獨有的 (4) 這是繼英國 501Y V1 變體和南非 501Y V2 變體之後,最近第三次檢測到主要國際變體這些突變變體的傳播性和致病性迫切需要進一步研究(5-6)。
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This case report provides a brief overview of the significance of macrodontia, along with presenting a case of KBG syndrome with atypical features in a South African, 16-year-old female.
本病例報告簡要概述了巨牙症的重要性,並介紹了一名 16 歲南非女性的具有非典型特徵的 KBG 綜合徵病例。
本病例報告簡要概述了巨牙症的重要性,並介紹了一名 16 歲南非女性的具有非典型特徵的 KBG 綜合徵病例。
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South African sentence examples within receptor angiotensin converting
Further analysis identified allosteric binders to host receptor angiotensin-converting enzyme 2, which were able to inhibit the entry of pseudoparticles bearing spike protein of wild type SARS-CoV-2 as well as South African B.
進一步的分析確定了宿主受體血管緊張素轉換酶 2 的變構結合劑,它們能夠抑制帶有野生型 SARS-CoV-2 以及南非 B.
進一步的分析確定了宿主受體血管緊張素轉換酶 2 的變構結合劑,它們能夠抑制帶有野生型 SARS-CoV-2 以及南非 B.
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Further investigation resulted in the identification of allosteric binders to host receptor angiotensin-converting enzyme 2; these compounds were then shown to inhibit the entry of pseudoparticles bearing spike protein of wild-type SARS-CoV-2, as well as South African B.
進一步的研究發現了宿主受體血管緊張素轉換酶 2 的變構粘合劑;這些化合物隨後被證明可以抑制帶有野生型 SARS-CoV-2 以及南非乙型肝炎病毒刺突蛋白的假顆粒的進入。
進一步的研究發現了宿主受體血管緊張素轉換酶 2 的變構粘合劑;這些化合物隨後被證明可以抑制帶有野生型 SARS-CoV-2 以及南非乙型肝炎病毒刺突蛋白的假顆粒的進入。
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South African sentence examples within per day visit
For instance, a visit to the website of the Addo Elephant National Park reveals that SANParks asks different prices – for South African citizens and residents R30 per day visit, SADC nationals R60 per day visit, and foreign visitors R130 per day visit to the Addo Elephant National Park.
例如,訪問 Addo Elephant National Park 的網站顯示,SANParks 要求不同的價格——南非公民和居民每天訪問 R30,SADC 國民每天訪問 R60,外國遊客每天訪問 Addo Elephant 130國家公園。
例如,訪問 Addo Elephant National Park 的網站顯示,SANParks 要求不同的價格——南非公民和居民每天訪問 R30,SADC 國民每天訪問 R60,外國遊客每天訪問 Addo Elephant 130國家公園。
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South African sentence examples within amino acid mutation
Using complementary in silico approaches, the effects of OBI-associated amino acid mutations on HBV protein function in HBV/HIV-positive ART-naïve South Africans were evaluated.
使用計算機補充方法,評估了 OBI 相關氨基酸突變對 HBV/HIV 陽性 ART 未接受過南非人的 HBV 蛋白功能的影響。
使用計算機補充方法,評估了 OBI 相關氨基酸突變對 HBV/HIV 陽性 ART 未接受過南非人的 HBV 蛋白功能的影響。
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South African sentence examples within Black South African
This analysis of black South African fiction, translated into English, pivots on a century-old aberration, the Natives Land Act of 1913, which assigned 90% of the land to a white minority.
這種對南非黑人小說的分析,翻譯成英文,以一個世紀以來的反常現象為中心,即 1913 年的土著土地法案,該法案將 90% 的土地分配給了少數白人。
這種對南非黑人小說的分析,翻譯成英文,以一個世紀以來的反常現象為中心,即 1913 年的土著土地法案,該法案將 90% 的土地分配給了少數白人。
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While RRR Dhlomo (Rolfes Robert Reginald Dhlomo) is known for being the first black South African to publish a novella in English, An African Tragedy (1928), and for having published English short stories in Sjambok and The Bantu World in the late 1920s and early 1930s, he made a greater impact on isiZulu literature as a historical and fictional novelist.
雖然 RRR Dhlomo (Rolfes Robert Reginald Dhlomo) 是第一個用英語出版中篇小說《非洲悲劇》(1928 年)的南非黑人,並在 1920 年代後期在 Sjambok 和 The Bantu World 發表了英文短篇小說, 1930年代初期,他作為歷史和虛構小說家對伊西祖魯文學產生了更大的影響。
雖然 RRR Dhlomo (Rolfes Robert Reginald Dhlomo) 是第一個用英語出版中篇小說《非洲悲劇》(1928 年)的南非黑人,並在 1920 年代後期在 Sjambok 和 The Bantu World 發表了英文短篇小說, 1930年代初期,他作為歷史和虛構小說家對伊西祖魯文學產生了更大的影響。
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South African sentence examples within Among South African
We determined the prevalence of stunting and examined whether stunting and associated risk factors (low dietary diversity, insufficient hemoglobin, food insecurity, and soil-transmitted helminth (STH) infections) are associated with academic achievement and cognitive function among South African children living in marginalized communities.
我們確定了發育遲緩的患病率,並檢查了發育遲緩和相關風險因素(飲食多樣性低、血紅蛋白不足、糧食不安全和土壤傳播的蠕蟲 (STH) 感染)是否與生活在邊緣化的南非兒童的學業成就和認知功能相關社區。
我們確定了發育遲緩的患病率,並檢查了發育遲緩和相關風險因素(飲食多樣性低、血紅蛋白不足、糧食不安全和土壤傳播的蠕蟲 (STH) 感染)是否與生活在邊緣化的南非兒童的學業成就和認知功能相關社區。
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The health implication of body weight burden needs rapid and effective interventions, focusing on factors such as rural, education, population group, older age 45–49 years, and Provinces (Northern Cape, Eastern Cape, and KwaZulu-Natal) – the high-risk groups identified herein are of most importance to curb the growing burden among South African women of reproductive age.
體重負擔對健康的影響需要快速有效的干預措施,重點關注諸如農村、教育、人口群體、45-49 歲的老年人和各省(北開普省、東開普省和誇祖魯-納塔爾省)等因素。本文確定的風險群體對於遏制南非育齡婦女日益增加的負擔至關重要。
體重負擔對健康的影響需要快速有效的干預措施,重點關注諸如農村、教育、人口群體、45-49 歲的老年人和各省(北開普省、東開普省和誇祖魯-納塔爾省)等因素。本文確定的風險群體對於遏制南非育齡婦女日益增加的負擔至關重要。
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South African sentence examples within Rural South African
South African sentence examples within Two South African
The present study examined the spatial and temporal distribution of fish and invertebrate larvae, simultaneously among several microhabitats, within two South African mangrove forests.
本研究檢查了兩個南非紅樹林內的幾個微生境中魚類和無脊椎動物幼蟲的空間和時間分佈。
本研究檢查了兩個南非紅樹林內的幾個微生境中魚類和無脊椎動物幼蟲的空間和時間分佈。
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The two South African spices named Lippia javanica (Izinziniba) and Foeniculum vulgare (Imbambosi) were studied for its proximate principles, minerals, vitamins and anti-nutrients properties.
研究了名為 Lippia javanica (Izinziniba) 和 Foeniculum vulgare (Imbambosi) 的兩種南非香料的近似原理、礦物質、維生素和抗營養特性。
研究了名為 Lippia javanica (Izinziniba) 和 Foeniculum vulgare (Imbambosi) 的兩種南非香料的近似原理、礦物質、維生素和抗營養特性。
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South African sentence examples within Young South African
Presently, some of the greatest social problems faced by young South Africans are COVID-19, employment, and climate change.
目前,年輕的南非人面臨的一些最大的社會問題是 COVID-19、就業和氣候變化。
目前,年輕的南非人面臨的一些最大的社會問題是 COVID-19、就業和氣候變化。
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This article addresses this gap by critically exploring how young South African adults used discourses of balance to make sense of what it means to be a healthy person and highlights the implications of these discourses for identity.
本文通過批判性地探討年輕的南非成年人如何使用平衡話語來理解成為健康人的意義,並強調了這些話語對身份的影響,從而解決了這一差距。
本文通過批判性地探討年輕的南非成年人如何使用平衡話語來理解成為健康人的意義,並強調了這些話語對身份的影響,從而解決了這一差距。
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South African sentence examples within Three South African
We collected data from three South African higher education institutions (HEI) offering emergency medical care qualifications.
我們從提供緊急醫療護理資格的三所南非高等教育機構 (HEI) 收集數據。
我們從提供緊急醫療護理資格的三所南非高等教育機構 (HEI) 收集數據。
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This chapter explores how three South African MNCs ventured north into Africa and what this meant for their practice of HRM.
本章探討了三個南非跨國公司如何向北進軍非洲,以及這對他們的人力資源管理實踐意味著什麼。
本章探討了三個南非跨國公司如何向北進軍非洲,以及這對他們的人力資源管理實踐意味著什麼。
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South African sentence examples within White South African
We sequenced the IL-8 gene of 109 black and 32 white South African (SA) individuals and conducted detailed characterization of gene variation and haplotype structure.
我們對 109 名黑人和 32 名南非白人 (SA) 個體的 IL-8 基因進行了測序,並對基因變異和單倍型結構進行了詳細表徵。
我們對 109 名黑人和 32 名南非白人 (SA) 個體的 IL-8 基因進行了測序,並對基因變異和單倍型結構進行了詳細表徵。
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Against this historical backdrop, Cole’s analysis of white South African contemporary theatremakers becomes more critical as she moves into the 1990s and the present in the following chapters of the book.
在這種歷史背景下,隨著她進入 1990 年代和本書後續章節,科爾對南非白人當代戲劇製作人的分析變得更加重要。
在這種歷史背景下,隨著她進入 1990 年代和本書後續章節,科爾對南非白人當代戲劇製作人的分析變得更加重要。
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South African sentence examples within Within South African
This study describes the development of a CDI intervention informed by the local context within South African public district level hospitals, and analyzes the CDI intervention development, implementation process and adaptations to understand acceptance, uptake, successes, and failures of the CDI intervention.
本研究描述了南非公立區級醫院根據當地情況制定的 CDI 干預措施,並分析了 CDI 干預措施的發展、實施過程和適應情況,以了解 CDI 干預措施的接受、採用、成功和失敗。
本研究描述了南非公立區級醫院根據當地情況制定的 CDI 干預措施,並分析了 CDI 干預措施的發展、實施過程和適應情況,以了解 CDI 干預措施的接受、採用、成功和失敗。
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This paper excavates and historically contextualizes the political theory of a largely neglected thinker within South African black intellectual history, Sam C.
本文挖掘並在歷史背景下將南非黑人思想史上一位很大程度上被忽視的思想家 Sam C.
本文挖掘並在歷史背景下將南非黑人思想史上一位很大程度上被忽視的思想家 Sam C.
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South African sentence examples within Urban South African
In an urban South African community, consecutive women living with (n = 479) and without (n = 510) HIV were enrolled and prospectively followed to delivery.
在南非的一個城市社區,連續感染 (n = 479) 和未感染 (n = 510) 艾滋病毒的婦女被納入並前瞻性地跟踪分娩。
在南非的一個城市社區,連續感染 (n = 479) 和未感染 (n = 510) 艾滋病毒的婦女被納入並前瞻性地跟踪分娩。
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Our findings report modest relationships between maternal stress specific to early gestation as likely important to birth outcomes in this urban South African sample.
我們的研究結果報告了孕早期特有的母體壓力之間的適度關係,這可能對南非城市樣本中的出生結果很重要。
我們的研究結果報告了孕早期特有的母體壓力之間的適度關係,這可能對南非城市樣本中的出生結果很重要。
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South African sentence examples within Several South African
Several South African universities do not require students to have completed Accounting at secondary school level in order to enrol for a degree in Accounting.
一些南非大學不要求學生在中學階段完成會計才能註冊會計學位。
一些南非大學不要求學生在中學階段完成會計才能註冊會計學位。
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Participants were recruited at a public hospital in Cape Town and through several South African endometriosis organizations.
參與者是在開普敦的一家公立醫院和幾個南非子宮內膜異位症組織中招募的。
參與者是在開普敦的一家公立醫院和幾個南非子宮內膜異位症組織中招募的。
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South African sentence examples within Central South African
Outbreaks have been reported in Africa and Asia since the early 1950s, from three CHIKV lineages: West African, East Central South African, and Asian Urban.
自 1950 年代初以來,非洲和亞洲已有暴發報導,來自三個 CHIKV 譜系:西非、南非中東部和亞洲城市。
自 1950 年代初以來,非洲和亞洲已有暴發報導,來自三個 CHIKV 譜系:西非、南非中東部和亞洲城市。
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Outbreaks have been reported in Africa and Asia since the early 1950s, from three CHIKV lineages: West African, East Central South African, and Asian Urban.
自 1950 年代初以來,非洲和亞洲已有暴發報導,來自三個 CHIKV 譜系:西非、南非中東部和亞洲城市。
自 1950 年代初以來,非洲和亞洲已有暴發報導,來自三個 CHIKV 譜系:西非、南非中東部和亞洲城市。
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South African sentence examples within Amongst South African
ABSTRACT Following the collapse of Saambou bank in February 2002, contagion rapidly spread amongst South African small and medium-sized banks.
摘要 自 2002 年 2 月 Saambou 銀行倒閉後,危機在南非中小型銀行間迅速蔓延。
摘要 自 2002 年 2 月 Saambou 銀行倒閉後,危機在南非中小型銀行間迅速蔓延。
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My intention is to continue the conversation, especially amongst South African classicists, about how to tackle the thorny question of decolonizing the content and teaching of the Classics in our universities.
我的目的是繼續對話,尤其是在南非古典主義者之間,討論如何解決我們大學經典內容和教學非殖民化的棘手問題。
我的目的是繼續對話,尤其是在南非古典主義者之間,討論如何解決我們大學經典內容和教學非殖民化的棘手問題。
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South African sentence examples within Pregnant South African
Conclusion and Global Health Implications: COVID-positive pregnant South African women were commonly symptomatic, but incidence of adverse fetal outcomes was low.
結論和全球健康影響:COVID 陽性的南非孕婦通常有症狀,但不良胎兒結局的發生率很低。
結論和全球健康影響:COVID 陽性的南非孕婦通常有症狀,但不良胎兒結局的發生率很低。
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Despite the high prevalence of HIV in pregnant South African women, little is known about the effects of ART on the cardiovascular health of the mother and offspring.
儘管南非孕婦的 HIV 感染率很高,但人們對 ART 對母親和後代心血管健康的影響知之甚少。
儘管南非孕婦的 HIV 感染率很高,但人們對 ART 對母親和後代心血管健康的影響知之甚少。
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South African sentence examples within Seven South African
We investigated the performance of point‐of‐care (POC) tests and dried blood spots (DBS) for HCV antibody and HCV RNA quantification in individuals at higher risk for HCV (people who use and inject drugs, sex workers and men who have sex with men) in seven South African cities.
我們調查了 HCV 抗體和 HCV RNA 定量在 HCV 高危人群(吸毒者、性工作者和有性行為的男性)中的即時 (POC) 測試和乾血斑 (DBS)與男性)在南非的七個城市。
我們調查了 HCV 抗體和 HCV RNA 定量在 HCV 高危人群(吸毒者、性工作者和有性行為的男性)中的即時 (POC) 測試和乾血斑 (DBS)與男性)在南非的七個城市。
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Thirteen teams (radiation oncologist, medical physicist and radiation therapy technologist) from Africa attended the course between 2015 and 2019, with additional participants from seven South African and four international centres.
2015 年至 2019 年間,來自非洲的 13 個團隊(放射腫瘤學家、醫學物理學家和放射治療技術專家)參加了該課程,另外還有來自 7 個南非和 4 個國際中心的參與者。
2015 年至 2019 年間,來自非洲的 13 個團隊(放射腫瘤學家、醫學物理學家和放射治療技術專家)參加了該課程,另外還有來自 7 個南非和 4 個國際中心的參與者。
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South African sentence examples within Fmy South African
This research, therefore, examined the Euclidean geometry learning experiences of 16 Grade 11 students from four South African secondary schools.
因此,本研究考察了來自四所南非中學的 16 名 11 年級學生的歐幾里得幾何學習經歷。
因此,本研究考察了來自四所南非中學的 16 名 11 年級學生的歐幾里得幾何學習經歷。
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AIM OF THE STUDY
The aim of the study was to evaluate the potential of four South African Croton species extracts (Croton gratissimus, Croton pseudopulchellus, Croton sylvaticus, and Croton steenkampianus) for anti-inflammatory activity targeting the TLR4 signalling pathway and to assess the potential risk for hepatotoxicity and genotoxicity using an in vitro cellomics approach.
研究目的
該研究的目的是評估四種南非巴豆物種提取物(Croton gratissimus、Croton pseudopulchellus、Croton sylvaticus 和 Croton steenkampianus)針對 TLR4 信號通路的抗炎活性的潛力,並評估潛在的肝毒性和肝毒性風險。使用體外細胞組學方法的基因毒性。
研究目的 該研究的目的是評估四種南非巴豆物種提取物(Croton gratissimus、Croton pseudopulchellus、Croton sylvaticus 和 Croton steenkampianus)針對 TLR4 信號通路的抗炎活性的潛力,並評估潛在的肝毒性和肝毒性風險。使用體外細胞組學方法的基因毒性。
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