Introduction to Sensitive Luminescence

This work should help design highly sensitive luminescence detection methods and develop experiments to explore dynamic phenomena involving ultra-weak luminescence in biology, chemistry, and material sciences.

On the basis of the excellent thermal and chemical as well as superior luminescence stabilities in water and solutions with different pHs, 1 can serve as the simple, rapid, and highly selective and sensitive luminescence detection of the carcinoid biomarkers 5-hydroxytryptamine (HT) and its metabolite 5-hydroxyindole-3-acetic acid (HIAA) with detection limits of nanomolar magnitude in water and in simulated blood plasma and urine systems.

Due to their environmental sensitive luminescence properties, the acidity-responsive optical properties can be achieved by rational design of the molecular structures.

Designing a molecule with pH, temperature and ion concentration sensitive luminescence properties is always fascinating.

Compound 4 shows sensitive luminescence quenching response to nitrobenzene (NB), and the corresponding quenching constant (Ksv) and detection limit are 2.

Compound 4 shows the apparent yellow emission with the maximum at 551 nm while exciting at 333 nm, and displays sensitive luminescence quenching response to nitrobenzene with quenching constant (Ksv) of 5.

The benign luminescence of the tetraphenylethylene-based ligand provides this material ability as potential sensor via sensitive luminescence response.

More importantly, the sensitive luminescence response of the AuNPs@CS from the acidic organelle lysosome to the neutral cytoplasm demonstrates the great potential in optical intracellular tracking.