Introduction to Sensitive Assessment

The 3N method thus allows for objective and sensitive assessment of CHO clustering and thereby encourages broad and global implementation of the test as an alternative to the HIST.

We present a robust, fresh-frozen approach to immunohistochemistry (IHC), without committing the tissue to IHC via fixation and cryopreservation while maintaining long-term storage, using LiCor-based infrared (IR) quantification for sensitive assessment of TH in immunoreacted midbrain sections for quantitative comparison across studies.

For a sensitive assessment of pathological gait patterns, a comprehensive analysis and processing of several gait analysis systems is necessary.

Substantial and functional characteristics of BP including simplicity of operation, optical properties, high carrier mobility, stronger immobilization of receptors and biomolecules, electronic bridging playing important role in the highly selective and sensitive assessment of analyte.

Our findings present a more comprehensive set of outcome metrics, which, once combined, provide a more detailed and sensitive assessment of overall treatment outcomes.

As depression has a negative influence on diabetes management as well as treatment of diabetic patients, sensitive assessment and timely intervention are necessary.

Furthermore, the validation of this technology for imaging of human lacunar properties establishes the quality and reliability required for the accurate, precise, and sensitive assessment of osteocyte morphometry in clinical bone biopsies.

Importantly, seroprevalence decreased with age, indicating that children are a suitable group for sensitive assessment of recent M.

The so-called suppression of the head impulse test (SHIMPs) represents a modification of the video head impulse test (HIMP) and is used for a more sensitive assessment of residual vestibular functions.

Conclusions An activity-specific intensity schema operationalized measurement of parent engagement in a complex, unbalanced research design and can serve as a template for more sensitive assessment of parent engagement.

Digital technology affords the opportunity to provide objective, frequent, and sensitive assessment of disease outside of the clinic environment.

These biosensors harness the high affinity and specificity of antibodies and aptamers, and unique conductive properties, biocompatibility, large surface area, and chemical stability of nanomaterials for selective and sensitive assessment of the HER2.

Whilst this study supports the role of a mesh as a useful adjunct, larger studies and long-term follow-up would provide more sensitive assessments of its efficacy.

Hospital planners should consider ward size, specialty, and capacity-breach tolerance in determining a more sensitive assessment of bed occupancy requirement.

The smartphone App we created enabled reliable and sensitive assessment of standing postural sway within different task conditions, in both relatively healthy younger and older adults.

Observations based on ∆SPL provided some indication that a more sensitive assessment of sleep may be one that considers variations in wind turbine SPL throughout the sleep period time.

Using molecular, cellular, and genomic analyses, we demonstrated that a recipient’s personalized humanized mouse provided the most sensitive assessment of allogeneic responsiveness to potential donors.

This will allow a sensitive assessment of a wide range of cognitions linked to social interaction (empathy, perspective taking, traumatic experiences, etc.

In conclusion, these results indicate that consideration for intrauterine position, maternal weight, and number of feti per horn provides a more sensitive assessment of FGR from rodent reproductive and developmental studies.

While the pandemic has demonstrated that the public health responses of migrant host societies are deeply intertwined with policies as well as local rules and constraints, the promotion and provision of safe, timely and appropriate palliative care can be achieved through a sensitive assessment of differential contexts of diversity.

001$ </tex-math></inline-formula>) in both laboratory and home settings, revealing that the smartphone App enabled reliable and sensitive assessment of standing posture in both healthy younger and older adults.

As in glaucoma and other optic neuropathies cellular dysfunction often precedes cell death, sensitive assessment of retinal ganglion cell (RGC) function represents a key outcome measure for neuroprotective strategies aimed at targeting distressed but still viable cells.

FOMs provide both clinicians and patients with a more detailed and sensitive assessment of overall treatment outcomes and the timeframe of functional recovery.

Therefore, timely, specific, and sensitive assessment of the malignancy is vital.

We discuss two possible interpretations for this finding: our effort task may have been a more sensitive assessment of loss aversion than the task involving choices between prospects; alternatively, the processes underlying how much effort people choose to exert may partially differ from those engaged by choices between prospects.

Left atrial volume provides a more sensitive assessment of left atrial enlargement, which is an important predictor of AF, providing incremental information beyond that afforded by the clinical risk factors and conventional M mode LA dimension.

To overcome these limitations, we introduced the photoconvertible protein Dendra2 into the MAP1LC3B locus of human cells via CRISPR/Cas9 genome editing, enabling accurate and sensitive assessments of autophagy in living cells by optical pulse labeling.

Furthermore, the validation of this technology for imaging of human lacunar properties establishes the quality and reliability required for the accurate, precise, and sensitive assessment of osteocyte morphometry in clinical bone biopsies.

This study was designed to test the hypothesis that the flow of RBCs through a network of microfluidic capillaries could provide a more sensitive assessment of the progressive impairment of RBC deformability during hypothermic storage than ektacytometry.

The Y-BOCS-II, which has demonstrated sound psychometric properties (4), advances the field through a higher ceiling (score range 0–50) that allows for more accurate and sensitive assessment of those with more severe symptomology.

To overcome these limitations, we introduced the photoconvertible protein Dendra2 into the MAP1LC3B locus of human cells via CRISPR/Cas9 genome editing, enabling accurate and sensitive assessments of autophagy in living cells by optical pulse labeling.

Four MR-based neuroimaging modalities have been used to examine recovery from pediatric TBI longitudinally: (1) T1-weighted structural MRI is sensitive to morphological changes in gray matter volume and cortical thickness, (2) diffusion-weighted MRI is sensitive to changes in the microstructural integrity of white matter, (3) MR spectroscopy provides a sensitive assessment of metabolic and neurochemical alterations in the brain, and (4) functional MRI provides insight into the functional changes that occur as a result of structural damage and typical developmental processes.

The case reports show that the training sensitized and supported the case managers supported the case managers when dealing with differing illness concepts, differing illness concepts, culture-sensitive assessment, or work with language mediators.

Keywords health literacy assessment; primary health care; South Africa; developing countries; public health service; context-sensitive assessment.

Advanced imaging modalities, such as fluorodeoxyglucose positron emission tomography scanning, and the widespread availability of magnetic resonance imaging have led to more sensitive assessment of organ involvement and disease activity.

The aim of our study was to perform a systematical calibration of sperm concentration in an IVF/IVC system, using an outbred mouse strain, and further determine the sperm concentration that furnishes a sensitive assessment of sperm fertilizing capacity in relation to reprotoxic evaluations.

Incorporating PROMIS measures into research and clinical care may provide a more sensitive assessment of symptomatic response to OSA treatment.

• “SyMRI” allows a faster and more sensitive assessment of myelination compared with standard MR sequences.

This study examines the performance of a three-part nuclear DNA analysis workflow for teeth samples based on (1) improved dental tissue recovery using the Dental Forensic Kit (DFK MR ) (Universidad de los Andes) and DNA extraction with QuickExtract™ FFPE DNA Extraction Kit (Lucigen®), (2) quantification with InnoQuant® HY (InnoGenomics Technologies) for sensitive assessment of total human and male DNA quantity/quality, and (3) massively parallel sequencing for simultaneous genotyping of 231 short tandem repeat (STR) and single-nucleotide polymorphism (SNP) markers with the ForenSeq® DNA Signature Prep Kit (Verogen, Inc.

Advanced functional imaging has provided tools needed for the sensitive assessment of functional brain activities and also functional abnormalities in various brain regions.

We hypothesized that machine learning derived 3D LV models may provide a more sensitive assessment of remodelling and sex-related differences in AS than conventional measurements.

STRENGTH & LIMITATIONS Strengths of our study include the Veterans Affairs population analyzed, as well as rigorous inclusion criteria that allowed for a sensitive assessment of postoperative renal function.

Plain radiographs have been the default modality to evaluate loosening, although radiographs provide a relatively insensitive assessment of integration; cross-sectional modalities may provide a more detailed evaluation but traditionally have suffered from metal-related artifacts.

With emerging insights into prevailing inflammatory and neuroinflammatory mechanisms that are involved in the pathogenesis of severe mental disorders, the interdependent aspects of sensitive assessment and potential clinical relevance of mild neuroinflammation are becoming more apparent and of increasing clinical interest.

Global measures of proteins in tissues or in the circulation provide a broad assessment of the proteome that can be extremely useful for discovery, and targeted proteomic measures can yield specific and sensitive assessments of specific peptides and proteins.

While no differences in back pain were observed, biomechanical measures were sensitive assessments for evaluating gestational LBP-related mobility impairment and showed group differences.