Randomized Efficacy(隨機功效)到底是什麼？
Randomized Efficacy 隨機功效 - These data provide a foundation for larger randomized efficacy trials of the telephone-based CST intervention. [1] We report findings from a pretest-posttest cluster randomized efficacy trial with one fixed between-subjects factor to test the effects of teacher-delivered SEL instruction against those of business as usual (BAU). [2] This study sought to estimate the net benefits and return on investment (ROI, %) of the Coping and Promoting Strength (CAPS) program to families and insurers, respectively, using data from a multi-year follow up of 136 US families who had participated in a randomized efficacy trial of CAPS. [3] Introduction: An important gap between randomized efficacy research and real-world implementation of complementary therapies is the role of patient preferences in influencing engagement and outcome. [4] Study accrual and attrition, as well as intervention adherence, will inform future, larger randomized efficacy trials of the intervention. [5] Data from a randomized efficacy trial of the ChAdOx1 nCoV-19 (AZD1222) vaccine in the United Kingdom was analyzed to determine the antibody levels associated with protection against SARS-CoV-2. [6] Methods and findings We nested a cluster randomized trial within a double-blind, placebo-controlled randomized efficacy trial to assess the effect of 3 prenatal nutritional supplements (lipid-based nutrient supplement [LNS], multiple micronutrient supplement [MMS], or iron–folic acid [IFA]) on infant immune response (n = 53 villages and 1,525 infants with valid serology results: 794 in the vaccine group and 731 in the placebo group). [7] The present study reports corollary child outcomes from a cluster randomized efficacy trial examining effects of a PD intervention versus business-as-usual (BAU) PD. [8] Findings from this survey will inform the establishment of an ongoing birth defects surveillance system and a randomized efficacy trial for prevention of anemia and birth defects in Southern India. [9] report the results of a double-blind randomized efficacy trial of 143 patients undergoing thoracoscopic lung resection surgery. [10] This study presents findings from a randomized effectiveness trial of the New Beginnings Program (NBP), which has demonstrated efficacy in 2 prior randomized efficacy trials. [11] As evidence-based family treatments for adolescent substance use and conduct problems gain traction, cutting edge research moves beyond randomized efficacy trials to address questions such as how these treatments work and how best to disseminate them to community settings. [12] The objective of this randomized efficacy feeding trial was to determine the effects of consuming iron-biofortified beans (Fe-Beans) on the iron status in children, compared to control beans (Control-Beans). [13] A classroom randomized efficacy trial conducted over four years in 7 community-based preschool and 6 Head Start programs investigated effects of the Second Step Early Learning (SSEL) curriculum on end of preschool executive functioning (EF) and social-emotional (SE) skills in low-income children. [14] Findings from the biomarker survey will inform the development of a randomized efficacy trial for the prevention of anemia and birth defects in Southern India. [15]這些數據為基於電話的 CST 干預的更大規模隨機療效試驗提供了基礎。 [1] 我們報告了一項前測後測集群隨機功效試驗的結果，該試驗具有一個固定的受試者間因素，以測試教師提供的 SEL 教學與一切照舊 (BAU) 教學的效果。 [2] 本研究旨在利用對 136 個參與的美國家庭的多年隨訪數據，分別估算家庭和保險公司的應對和促進力量 (CAPS) 計劃的淨收益和投資回報率 (ROI，%)在 CAPS 的隨機療效試驗中。 [3] 簡介：隨機療效研究與補充療法的實際實施之間的一個重要差距是患者偏好在影響參與和結果方面的作用。 [4] 研究應計和減員，以及乾預依從性，將為未來更大的干預隨機療效試驗提供信息。 [5] 分析了來自英國 ChAdOx1 nCoV-19 (AZD1222) 疫苗的隨機功效試驗的數據，以確定與針對 SARS-CoV-2 的保護相關的抗體水平。 [6] 方法和結果 我們在一項雙盲、安慰劑對照的隨機療效試驗中嵌套了一項整群隨機試驗，以評估 3 種產前營養補充劑（基於脂質的營養補充劑 [LNS]、多種微量營養素補充劑 [MMS] 或鐵-葉酸 [IFA]）對嬰兒免疫反應的影響（n = 53 個村莊和 1,525 名具有有效血清學結果的嬰兒：疫苗組 794 人，安慰劑組 731 人）。 [7] 本研究報告了一組隨機療效試驗的推論兒童結果，該試驗檢查了 PD 干預與一切照舊 (BAU) PD 的效果。 [8] 這項調查的結果將為在印度南部建立持續的出生缺陷監測系統和預防貧血和出生缺陷的隨機功效試驗提供信息。 [9] 報告對 143 名接受胸腔鏡肺切除手術的患者進行的雙盲隨機療效試驗的結果。 [10] 本研究介紹了新起點計劃 (NBP) 的一項隨機有效性試驗的結果，該試驗已在之前的 2 項隨機有效性試驗中證明了有效性。 [11] 隨著針對青少年物質使用和行為問題的基於證據的家庭治療越來越受到關注，前沿研究超越了隨機療效試驗，以解決諸如這些治療如何發揮作用以及如何最好地將它們傳播到社區環境等問題。 [12] 這項隨機功效餵養試驗的目的是確定食用鐵生物強化豆 (Fe-Beans) 與對照豆 (Control-Beans) 相比對兒童鐵狀態的影響。 [13] 在 7 個社區學前班和 6 個啟蒙計劃中進行了四年多的課堂隨機功效試驗，調查了第二步早期學習 (SSEL) 課程對學齡前執行功能 (EF) 和社會情感 (SE) 技能結束的影響低收入兒童。 [14] 生物標誌物調查的結果將為印度南部預防貧血和出生缺陷的隨機療效試驗的發展提供信息。 [15]
Larger Randomized Efficacy 更大的隨機功效
These data provide a foundation for larger randomized efficacy trials of the telephone-based CST intervention. [1] Study accrual and attrition, as well as intervention adherence, will inform future, larger randomized efficacy trials of the intervention. [2]這些數據為基於電話的 CST 干預的更大規模隨機療效試驗提供了基礎。 [1] 研究應計和減員，以及乾預依從性，將為未來更大的干預隨機療效試驗提供信息。 [2]
Cluster Randomized Efficacy 集群隨機功效
We report findings from a pretest-posttest cluster randomized efficacy trial with one fixed between-subjects factor to test the effects of teacher-delivered SEL instruction against those of business as usual (BAU). [1] The present study reports corollary child outcomes from a cluster randomized efficacy trial examining effects of a PD intervention versus business-as-usual (BAU) PD. [2]我們報告了一項前測後測集群隨機功效試驗的結果，該試驗具有一個固定的受試者間因素，以測試教師提供的 SEL 教學與一切照舊 (BAU) 教學的效果。 [1] 本研究報告了一組隨機療效試驗的推論兒童結果，該試驗檢查了 PD 干預與一切照舊 (BAU) PD 的效果。 [2]
randomized efficacy trial 隨機療效試驗
These data provide a foundation for larger randomized efficacy trials of the telephone-based CST intervention. [1] We report findings from a pretest-posttest cluster randomized efficacy trial with one fixed between-subjects factor to test the effects of teacher-delivered SEL instruction against those of business as usual (BAU). [2] This study sought to estimate the net benefits and return on investment (ROI, %) of the Coping and Promoting Strength (CAPS) program to families and insurers, respectively, using data from a multi-year follow up of 136 US families who had participated in a randomized efficacy trial of CAPS. [3] Study accrual and attrition, as well as intervention adherence, will inform future, larger randomized efficacy trials of the intervention. [4] Data from a randomized efficacy trial of the ChAdOx1 nCoV-19 (AZD1222) vaccine in the United Kingdom was analyzed to determine the antibody levels associated with protection against SARS-CoV-2. [5] Methods and findings We nested a cluster randomized trial within a double-blind, placebo-controlled randomized efficacy trial to assess the effect of 3 prenatal nutritional supplements (lipid-based nutrient supplement [LNS], multiple micronutrient supplement [MMS], or iron–folic acid [IFA]) on infant immune response (n = 53 villages and 1,525 infants with valid serology results: 794 in the vaccine group and 731 in the placebo group). [6] The present study reports corollary child outcomes from a cluster randomized efficacy trial examining effects of a PD intervention versus business-as-usual (BAU) PD. [7] Findings from this survey will inform the establishment of an ongoing birth defects surveillance system and a randomized efficacy trial for prevention of anemia and birth defects in Southern India. [8] report the results of a double-blind randomized efficacy trial of 143 patients undergoing thoracoscopic lung resection surgery. [9] This study presents findings from a randomized effectiveness trial of the New Beginnings Program (NBP), which has demonstrated efficacy in 2 prior randomized efficacy trials. [10] As evidence-based family treatments for adolescent substance use and conduct problems gain traction, cutting edge research moves beyond randomized efficacy trials to address questions such as how these treatments work and how best to disseminate them to community settings. [11] A classroom randomized efficacy trial conducted over four years in 7 community-based preschool and 6 Head Start programs investigated effects of the Second Step Early Learning (SSEL) curriculum on end of preschool executive functioning (EF) and social-emotional (SE) skills in low-income children. [12] Findings from the biomarker survey will inform the development of a randomized efficacy trial for the prevention of anemia and birth defects in Southern India. [13]這些數據為基於電話的 CST 干預的更大規模隨機療效試驗提供了基礎。 [1] 我們報告了一項前測後測集群隨機功效試驗的結果，該試驗具有一個固定的受試者間因素，以測試教師提供的 SEL 教學與一切照舊 (BAU) 教學的效果。 [2] 本研究旨在利用對 136 個參與的美國家庭的多年隨訪數據，分別估算家庭和保險公司的應對和促進力量 (CAPS) 計劃的淨收益和投資回報率 (ROI，%)在 CAPS 的隨機療效試驗中。 [3] 研究應計和減員，以及乾預依從性，將為未來更大的干預隨機療效試驗提供信息。 [4] 分析了來自英國 ChAdOx1 nCoV-19 (AZD1222) 疫苗的隨機功效試驗的數據，以確定與針對 SARS-CoV-2 的保護相關的抗體水平。 [5] 方法和結果 我們在一項雙盲、安慰劑對照的隨機療效試驗中嵌套了一項整群隨機試驗，以評估 3 種產前營養補充劑（基於脂質的營養補充劑 [LNS]、多種微量營養素補充劑 [MMS] 或鐵-葉酸 [IFA]）對嬰兒免疫反應的影響（n = 53 個村莊和 1,525 名具有有效血清學結果的嬰兒：疫苗組 794 人，安慰劑組 731 人）。 [6] 本研究報告了一組隨機療效試驗的推論兒童結果，該試驗檢查了 PD 干預與一切照舊 (BAU) PD 的效果。 [7] 這項調查的結果將為在印度南部建立持續的出生缺陷監測系統和預防貧血和出生缺陷的隨機功效試驗提供信息。 [8] 報告對 143 名接受胸腔鏡肺切除手術的患者進行的雙盲隨機療效試驗的結果。 [9] 本研究介紹了新起點計劃 (NBP) 的一項隨機有效性試驗的結果，該試驗已在之前的 2 項隨機有效性試驗中證明了有效性。 [10] 隨著針對青少年物質使用和行為問題的基於證據的家庭治療越來越受到關注，前沿研究超越了隨機療效試驗，以解決諸如這些治療如何發揮作用以及如何最好地將它們傳播到社區環境等問題。 [11] 在 7 個社區學前班和 6 個啟蒙計劃中進行了四年多的課堂隨機功效試驗，調查了第二步早期學習 (SSEL) 課程對學齡前執行功能 (EF) 和社會情感 (SE) 技能結束的影響低收入兒童。 [12] 生物標誌物調查的結果將為印度南部預防貧血和出生缺陷的隨機療效試驗的發展提供信息。 [13]