Introduction to Quantitative Pharmacology

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10.3390/ph12040179

In addition, a pre-conference workshop provided an opportunity for younger researchers to develop their theoretical knowledge in quantitative pharmacology.

27th Annual GP2A Medicinal Chemistry Conference

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10.1002/cpt.1355

This theme issue “From molecule to patient” brings to the foreground the many amazing technological advances of the past decade at the molecular level, including teaching old modalities new tricks, increasing experience in quantitative pharmacology and modeling, and simulation approaches, pharmacogenomics, and a dramatic shift to include special populations, such as pediatrics and geriatrics and, importantly, also orphan indications.

From Molecule to Patient and Ways to Get the Dose Precisely Right

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10.3389/fphar.2019.00605

In quantitative pharmacology, multi-parameter receptor models are needed to account for the complex nonlinear relationship between fractional occupancy and response that can occur due to the intermixing of the effects of partial receptor activation and post-receptor signal amplification.

A Receptor Model With Binding Affinity, Activation Efficacy, and Signal Amplification Parameters for Complex Fractional Response Versus Occupancy Data

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Quantitative Pharmacology
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Quantitative Pharmacology - In addition, a pre-conference workshop provided an opportunity for younger researchers to develop their theoretical knowledge in quantitative pharmacology. [1] This theme issue “From molecule to patient” brings to the foreground the many amazing technological advances of the past decade at the molecular level, including teaching old modalities new tricks, increasing experience in quantitative pharmacology and modeling, and simulation approaches, pharmacogenomics, and a dramatic shift to include special populations, such as pediatrics and geriatrics and, importantly, also orphan indications. [2] In quantitative pharmacology, multi-parameter receptor models are needed to account for the complex nonlinear relationship between fractional occupancy and response that can occur due to the intermixing of the effects of partial receptor activation and post-receptor signal amplification. [3]