Introduction to Gel Microcapsules

Membrane emulsification was used to produce a water-in-oil emulsion with the water-soluble polymer subsequently cross-linked to produce hydrogel microcapsules.

ABSTRACT We investigated the feasibility of agarose-gel microcapsules to cryopreserve extremely small numbers of sperm for assisted reproductive technology.

Results The dermal fibroblasts in alginate hydrogel microcapsules were round in shape, and were distributed as uniform clouds on the surface and gaps of the alginate.

Here, we present a multidisciplinary strategy to engineer novel vascularized human induced pluripotent stem cells (hiPSCs)-derived brain organoids system with biomimetic features using microfluidic hydrogel microcapsules.

Microfluidic encapsulation of cells/tissues in hydrogel microcapsules has attracted tremendous attention in the burgeoning field of cell-based medicine.

The powders were firstly encapsulated in hydrogel bubbles and further dispersed by T-shaped microfluidic flow to form the core/shell-structured powder in hydrogel microcapsules (P/H microcapsules).

We report a simple process to fabricate monodisperse tetra-arm poly(ethylene glycol) (tetra-PEG) hydrogel microcapsules with an aqueous core and a semipermeable hydrogel shell through the formation of aqueous two-phase system (ATPS) droplets consisting of a dextran-rich core and a tetra-PEG macromonomer-rich shell, followed by a spontaneous cross-end coupling reaction of tetra-PEG macromonomers in the shell.

However, this strategy has been limited by the inability to reproduce large volumes of standardized microcapsules and the lack of information on cell‐specific egress and timed release from hydrogel microcapsules.

In this study, we achieved pCPAs concentration (up to 3 M) vitrification by encapsulating HUVECs into core-shell alginate hydrogel microcapsules.

We discovered that MCF10A cells, a benign mammary cell line that forms growth-arrested polarized acini in Matrigel, transforms into cancer-like cells within the same Matrigel material following confinement in alginate shell hydrogel microcapsules.

Methacrylic anhydride-derived hydrogel microcapsules have unique properties, including reversibly tunable permeation, purification, and separation of dissolved molecular species.

The release period of rhodamine 6G can be up to 4 months when using a photocurable resin as the shell material, while the release of rhodamine 6G can be regulated via the osmolality of the incubation solution for porous hydrogel microcapsules.

In this study, polymeric nanofibre-integrated alginate (PNA) hydrogel microcapsules were designed using NIM technology.

Then, Design-Expert® software was used to optimize the production process of the hydrogel microcapsules.

In this study, we achieved pCPA concentration (up to 3 M) vitrification by encapsulating human umbilical vein endothelial cells (HUVECs) into core-shell alginate hydrogel microcapsules.

Hydrogel microcapsules having the ability to promote cell adhesion and proliferation are a useful tool for fabricating tissue in vitro.

The cytocompatibility of the 3D printed device is demonstrated by encapsulating mesenchymal stem cells in hydrogel microcapsules, which results in the controllable formation of stem cell spheroids that remain viable and metabolically active for at least 21 days.

This magnetically driven hydrogel microcapsules can provide a non-toxically, stable, high precision and high degrees of freedom way to achieve drug controlled release.