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Sensitive Fluorescent Oligonucleotide

In this work, a strategy for telomerase sensing by using hybridization‐sensitive fluorescent oligonucleotide probes is reported.

Live‐Cell Sensing of Telomerase Activity by Using Hybridization‐Sensitive Fluorescent Oligonucleotide Probes

Sensitive Fluorescent Oligonucleotide

Recently, exciton‐controlled hybridization‐sensitive fluorescent oligonucleotide (ECHO) probe, which shows strong emission in the near‐infrared region via hybridization to the target DNA and/or RNA strand, has been developed.

Photophysical properties of fluorescent imaging biological probes of nucleic acids: SAC‐CI and TD‐DFT Study

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fluorescent oligonucleotide probe

Using allele-specific fluorescent oligonucleotide probes, ddPCR can enumerate both mutant and wild-type alleles enabling highly sensitive detection and quantitation of the variant allele frequency of mutated genes.

Rare Variant Quantitation Using Droplet Digital PCR.

fluorescent oligonucleotide probe

In this work, a strategy for telomerase sensing by using hybridization‐sensitive fluorescent oligonucleotide probes is reported.

Live‐Cell Sensing of Telomerase Activity by Using Hybridization‐Sensitive Fluorescent Oligonucleotide Probes

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10.1021/acs.bioconjchem.9b00746

Fluorescent oligonucleotides that bind precisely, and sense target DNA or RNA, are useful tools for simple hybridization-based assays.

Fluorescent oligonucleotides with bis (prop-2-yn-1-yloxy) butane-1,3-diol scaffold rapidly detect disease associated nucleic acids.

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10.1039/c8an02070a

In particular, the development of AuNP-based fluorescent oligonucleotide (AuFO) probes targeted at living systems through fluorescence are drawing increasing attention and have become a current hot topic in biomedical research.

Gold nanoparticle based fluorescent oligonucleotide probes for imaging and therapy in living systems.

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10.1002/chem.201804706

The nanodevice was able to release the fluorescent oligonucleotide through the enzyme-mediated hydrolysis of urea to ammonia and the subsequent deprotonation of amino groups on the silica face.

A Versatile New Paradigm for the Design of Optical Nanosensors Based on Enzyme-Mediated Detachment of Labeled Reporters: The Example of Urea Detection.

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10.1126/science.aax7852

We report a robust, versatile approach called CRISPR live-cell fluorescent in situ hybridization (LiveFISH) using fluorescent oligonucleotides for genome tracking in a broad range of cell types, including primary cells.

CRISPR-mediated live imaging of genome editing and transcription

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What is/are Fluorescent Oligonucleotide?

Fluorescent Oligonucleotide - Fluorescent oligonucleotides that bind precisely, and sense target DNA or RNA, are useful tools for simple hybridization-based assays. [1] In particular, the development of AuNP-based fluorescent oligonucleotide (AuFO) probes targeted at living systems through fluorescence are drawing increasing attention and have become a current hot topic in biomedical research. [2] The nanodevice was able to release the fluorescent oligonucleotide through the enzyme-mediated hydrolysis of urea to ammonia and the subsequent deprotonation of amino groups on the silica face. [3] We report a robust, versatile approach called CRISPR live-cell fluorescent in situ hybridization (LiveFISH) using fluorescent oligonucleotides for genome tracking in a broad range of cell types, including primary cells. [4]

Sensitive Fluorescent Oligonucleotide

In this work, a strategy for telomerase sensing by using hybridization‐sensitive fluorescent oligonucleotide probes is reported. [1] Recently, exciton‐controlled hybridization‐sensitive fluorescent oligonucleotide (ECHO) probe, which shows strong emission in the near‐infrared region via hybridization to the target DNA and/or RNA strand, has been developed. [2]

fluorescent oligonucleotide probe

Using allele-specific fluorescent oligonucleotide probes, ddPCR can enumerate both mutant and wild-type alleles enabling highly sensitive detection and quantitation of the variant allele frequency of mutated genes. [1] In this work, a strategy for telomerase sensing by using hybridization‐sensitive fluorescent oligonucleotide probes is reported. [2] Herein, we propose a bioassay based on microgels endowed with optical fluorescent oligonucleotide probes for the detection of circulating endogenous hcmv-microRNAs. [3]