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10.1111/bph.14634

In all rodent alcohol drinking models tested so far, H3 receptor antagonists have reduced alcohol drinking and alcohol‐induced place preference and cue‐induced alcohol reinstatement.

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10.3791/57027

To this end, the following protocol utilizes two simple rodent drinking models to assess the preclinical efficacy of lead anti-alcohol compounds: two-bottle choice (TBC) and drinking in the dark (DID).

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Drinking Models

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Sep 18, 2024

What is/are Drinking Models?

Drinking Models - In all rodent alcohol drinking models tested so far, H3 receptor antagonists have reduced alcohol drinking and alcohol‐induced place preference and cue‐induced alcohol reinstatement. ^[1] To this end, the following protocol utilizes two simple rodent drinking models to assess the preclinical efficacy of lead anti-alcohol compounds: two-bottle choice (TBC) and drinking in the dark (DID). ^[2]