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Copenhagen City Heart

METHODS AND RESULTS In two prospective population-based studies, the Copenhagen General Population Study and the Copenhagen City Heart Study (N = 111,984 individuals), we first tested whether high plasma HDL cholesterol is associated with increased risk of any dementia and its subtypes.

Plasma HDL cholesterol and risk of dementia - observational and genetic studies.

Copenhagen City Heart

Asymptomatic women from the community-based Copenhagen City Heart Study served as reference group (n=102).

Impaired coronary flow velocity reserve is associated with cardiovascular risk factors but not with angina symptoms

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Kansa City Heart

Methods: A retrospective cohort analysis was performed on SARS-CoV-2 positive patients with AD at Columbia University Medical Center and Kansas City Heart Rhythm Institute.

B-PO05-164 AUTONOMIC DYSFUNCTION POST-COVID-19 INFECTION

Kansa City Heart

David’sMedical Center, Austin, Texas, USA 6 Kansas City Heart Rhythm Institute and Research Foundation, Kansas City, Kansas, USA.

His‐bundle pacing following transcatheter aortic valve replacement

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city heart study

METHODS AND RESULTS In two prospective population-based studies, the Copenhagen General Population Study and the Copenhagen City Heart Study (N = 111,984 individuals), we first tested whether high plasma HDL cholesterol is associated with increased risk of any dementia and its subtypes.

Plasma HDL cholesterol and risk of dementia - observational and genetic studies.

city heart study

However, the Copenhagen studies (City Heart Study and General Population Study) demonstrated U-shaped associations between HDL-C levels and cardiovascular mortality, and the Canadian CANHEART study also showed similar U-shaped associations between them.

To be Functional, or not to be Low in Cholesterol, that is the Clinical Concern when Evaluating Anti-Atherosclerotic Actions of High-Density Lipoproteins

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city heart rhythm

Methods: A retrospective cohort analysis was performed on SARS-CoV-2 positive patients with AD at Columbia University Medical Center and Kansas City Heart Rhythm Institute.

B-PO05-164 AUTONOMIC DYSFUNCTION POST-COVID-19 INFECTION

city heart rhythm

David’sMedical Center, Austin, Texas, USA 6 Kansas City Heart Rhythm Institute and Research Foundation, Kansas City, Kansas, USA.

His‐bundle pacing following transcatheter aortic valve replacement

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10.1007/978-3-319-76017-9_41

In the city heart of Bordeaux, then, a natural area, continuously evolving was born made up of a wild bush, cultivated fields and even an open-air farm to be eco-managed.

CS 11: Case Study 11: Communicating the Environment Through the Architectural Linguistic Code

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City Heart
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What is/are City Heart?

City Heart - In the city heart of Bordeaux, then, a natural area, continuously evolving was born made up of a wild bush, cultivated fields and even an open-air farm to be eco-managed. [1]

Copenhagen City Heart

METHODS AND RESULTS In two prospective population-based studies, the Copenhagen General Population Study and the Copenhagen City Heart Study (N = 111,984 individuals), we first tested whether high plasma HDL cholesterol is associated with increased risk of any dementia and its subtypes. [1] Asymptomatic women from the community-based Copenhagen City Heart Study served as reference group (n=102). [2] METHODS AND RESULTS  We determined normative values of peak atrial longitudinal strain (PALS), peak atrial contraction strain (PACS), and LA strain during the conduit phase (LACS) in 1641 healthy participants included in the fifth Copenhagen City Heart Study. [3] Methods All participants in the Copenhagen City Heart Study were followed from 1993 to 2016. [4] 910–920) report findings from long-term follow-up of participants in the Copenhagen City Heart Study (13). [5] Findings were validated independently in participants in the Copenhagen City Heart Study (CCHS). [6] The Copenhagen City Heart Study is a prospective study of diabetic and non‐diabetic individuals from the Danish general population with different physical activity levels. [7] METHODS We followed 1160 individuals aged 20-40 years from the Copenhagen City Heart Study from 1976-83 until 2001-03 to determine their lung function trajectory: 72 had persistent PRISm trajectory, 76 normal-to-PRISm trajectory, 155 PRISm-to-normal trajectory, and 857 had normal trajectory. [8] We included participants from two general population studies, the Copenhagen City General Population Study and the Copenhagen City Heart Study, to assess contemporary (year 2003–2017) and historical (1976–1983) occupational inhalant hazards. [9] We also studied 13 974 individuals from the Copenhagen City Heart Study recruited in 1976-78. [10] Participants will be matched by sex and age to controls from the Copenhagen General Population Study (CGPS) and the Copenhagen City Heart Study (CCHS). [11] METHODS AND RESULTS This prospective longitudinal study included 4466 participants from the fifth Copenhagen City Heart Study. [12] METHODS AND RESULTS We examined longitudinal changes of the LA between two visits in the Copenhagen City Heart Study (n = 1065). [13] Participants from the Copenhagen City Heart Study examined with echocardiography, including speckle tracking analyses, were included. [14] The study included 621 community-dwelling adults, mean age 75⋅2 ± 6⋅4 years, 58⋅9 % female, who had participated in the Copenhagen City Heart Study follow-up, and undergone interviews regarding food intake (preceding month), oral and general health (xerostomia, taste alterations, diseases, medication, alcohol consumption and smoking), clinical oral examination and measurements of unstimulated and chewing-stimulated whole saliva flow rates. [15] These changes are based on knowledge gained from longitudinal cohorts such as the Copenhagen City Heart Study, ECLIPSE, SPIROMICS and COPDGene, which have shed light on the natural history of the disease and clinical characteristics associated with exacerbations. [16] Using a Mendelian randomisation design, we examined 118,838 individuals from two Copenhagen cohorts, the Copenhagen General Population Study and the Copenhagen City Heart Study, and 440,328 individuals from the MEGASTROKE study. [17] Recent Findings Two observational studies (Cardiovascular Health in Ambulatory Care Research Team [CANHEART] and Copenhagen City Heart Study and the Copenhagen General Population Study [Copenhagen Heart Studies]) of adults without pre-existing ASCVD have shown a significant U-shaped association of HDL-C with all-cause and cause-specific mortality. [18] Ågesen and colleagues report the temporal trends in SCD in 14 562 participants followed in the Copenhagen City Heart. [19] We included 118,683 white Danes aged ≥ 20 from the Copenhagen General Population Study (2003–2015) and the Copenhagen City Heart Study (1991–94 and 2001–03). [20] 25 on (1) cardiovascular disease outcomes in two large population-based cohorts (Copenhagen City Heart Study and Copenhagen General Population Study, n = 106,018; and UK Biobank, n = 357,426) and additionally in an elderly population at risk for cardiovascular disease (n = 5241), and on (2) atherosclerotic plaque phenotypes in samples of patients who underwent endarterectomy (n = 1439). [21] These results were validated independently in the Copenhagen City Heart Study cohort. [22] METHODS AND RESULTS We performed 2DSTE analysis of 1997 members of the general population from the fifth round of the Copenhagen City Heart Study, who were free of cardiovascular disease and risk factors. [23] Participants from the 5th round of the Copenhagen City Heart Study, aged < 65 years old, answering a questionnaire regarding occupational physical activity, heavy occupational lifting, use of anti-hypertensive and heart medication, and data on blood pressure, cardiac structure and function, from an echocardiographic examination, were included. [24] DESIGN AND SETTING From the Danish general population, we studied 106,703 and 16,032 individuals in the Copenhagen General Population Study(CGPS) and the Copenhagen City Heart Study(CCHS) with median follow-up of respectively 9 and 32 years. [25] METHODS As part of the prospective Copenhagen City Heart Study, 8697 healthy adults completed a comprehensive questionnaire about leisure-time sports activities. [26] We used a Mendelian randomisation (MR) design in the China Kadoorie Biobank, the Copenhagen City Heart Study, and the Copenhagen General Population Study. [27] Methods: We included 112,457 nondiabetic individuals from the Copenhagen City Heart Study and the Copenhagen General Population Study and assessed their prospective risk of retinopathy, neuropathy, diabetic nephropathy, peripheral arterial disease (PAD), and myocardial infarction (MI) as a function of increasing glucose levels. [28] In the fifth examination of the Copenhagen City Heart Study, 2335 individuals gave consent to wear accelerometers (skin-attached; right thigh and iliac crest; 24 h/day, 7 consecutive days) of which 1670 fulfilled our inclusion criteria (≥16 h/day for ≥5 days; median wear time: 23. [29] METHODS AND RESULTS Characterization of the INSIG2 locus was followed by studies in over 107 000 individuals from the general population, the Copenhagen General Population Study and the Copenhagen City Heart Study, for associations of genetic variants with plasma lipids levels, with risk of myocardial infarction (MI) and with cardiovascular mortality. [30] Population and methods The study population included 6,740 individuals attending the 3rd cycle in 1991–94 of the Copenhagen City Heart Study, providing information on BMI, educational level, health behaviours, well-being, weight half-a-year earlier, and answers to four BWC questions about caring for body weight, assumed benefit of weight loss, current and past slimming experiences. [31] Methods This prospective study includes a total of 78 936 participants from the Copenhagen City Heart Study and the Copenhagen General Population Study, all without previous thromboembolic events and aged <65 years. [32] METHODS We used data from 6,807 participants attending the third survey of the Copenhagen City Heart Study in 1991-1994. [33] Methods Data from the third, fourth and fifth examinations of the Copenhagen City Heart Study were included. [34] (2) have examined the relationship between HDL-C concentrations and the risk of development of autoimmune disease in 2 population-based cohort studies—the Copenhagen General Population Study and the Copenhagen City Heart Study—that included 117341 individuals with baseline HDL-C measurements. [35] 923 individuals with COPD diagnosed similarly in the Copenhagen City Heart Study (CCHS) were used for replication analyses. [36] METHODS A total of 109,566 individuals from the Copenhagen General Population Study and the Copenhagen City Heart Study were genotyped for PCSK9 R46L (rs11591147), R237W (rs148195424), I474V (rs562556), and E670G (rs505151). [37] The Paris Prospective Study, the Lipid Research Clinics Follow-up Study, the Reykjavik study, and the European Prospective Investigation of Cancer (EPIC Norfolk) study showed a relationship between TG levels and CVD, while the Multiple Risk Factor Intervention Trial, the Copenhagen City Heart Study, the Copenhagen General Population Study and the Women’s Health Study found an even stronger relationship between non-fasting TG levels and CVD; as most people eat regularly throughout the day, non-fasting lipids may be a better indicator of mean lipid concentrations in the blood, and individuals are exposed to post-prandial TG most of the time. [38] METHODS From the Copenhagen General Population Study and the Copenhagen City Heart Study, 117865 men and women 20-100+ years of age with measurements of nonfasting plasma triglycerides at baseline were followed prospectively for development of acute pancreatitis. [39] Methods We undertook prospective studies of 2 cohorts enrolled in 1976 to 1978 (13,567 participants from the Copenhagen City Heart Study) and 2003 to 2015 (107,040 participants from the Copenhagen General Population Study). [40] METHODS We examined the association of plasma ferritin concentrations with risk of atrial fibrillation and heart failure in metaanalyses of 35799 men and women from 3 studies of the Danish general population: the Copenhagen City Heart Study, the Danish General Suburban Population Study, and the Copenhagen General Population Study. [41] Methods: Leukocyte TL was measured after diagnosis in 807 patients with non–small cell lung cancer (NSCLC) from the Princess Margaret Cancer Center in Toronto and assessed prospectively in 767 NSCLC cases from the Copenhagen City Heart Study and the Copenhagen General Population Study. [42] DESIGN We included 118,085 individuals from two prospective cohort studies, the Copenhagen City Heart Study and the Copenhagen General Population Study, with BMI measured at baseline. [43] METHODS From 2 studies of the general population-the Copenhagen General Population Study and the Copenhagen City Heart study-we included 107954 and 9387 individuals with baseline measurements of HDL cholesterol. [44] We also studied 1115 individuals with CVD from the CCHS (Copenhagen City Heart Study; 1991-1994) and the CIHDS (Copenhagen Ischemic Heart Disease Study; 1991-1993). [45] 8 9 Using data from individuals with COPD in the Copenhagen General Population Study (n=5262) and the Copenhagen City Heart Study (n=923), Ingebrigtsen et al tested the association of β2 adrenergic receptor polymorphisms Gly16Arg (rs1042713, c. [46]

Kansa City Heart

Methods: A retrospective cohort analysis was performed on SARS-CoV-2 positive patients with AD at Columbia University Medical Center and Kansas City Heart Rhythm Institute. [1] David’sMedical Center, Austin, Texas, USA 6 Kansas City Heart Rhythm Institute and Research Foundation, Kansas City, Kansas, USA. [2]

city heart study

METHODS AND RESULTS In two prospective population-based studies, the Copenhagen General Population Study and the Copenhagen City Heart Study (N = 111,984 individuals), we first tested whether high plasma HDL cholesterol is associated with increased risk of any dementia and its subtypes. [1] However, the Copenhagen studies (City Heart Study and General Population Study) demonstrated U-shaped associations between HDL-C levels and cardiovascular mortality, and the Canadian CANHEART study also showed similar U-shaped associations between them. [2] Asymptomatic women from the community-based Copenhagen City Heart Study served as reference group (n=102). [3] METHODS AND RESULTS  We determined normative values of peak atrial longitudinal strain (PALS), peak atrial contraction strain (PACS), and LA strain during the conduit phase (LACS) in 1641 healthy participants included in the fifth Copenhagen City Heart Study. [4] Methods All participants in the Copenhagen City Heart Study were followed from 1993 to 2016. [5] 910–920) report findings from long-term follow-up of participants in the Copenhagen City Heart Study (13). [6] Findings were validated independently in participants in the Copenhagen City Heart Study (CCHS). [7] The Copenhagen City Heart Study is a prospective study of diabetic and non‐diabetic individuals from the Danish general population with different physical activity levels. [8] METHODS We followed 1160 individuals aged 20-40 years from the Copenhagen City Heart Study from 1976-83 until 2001-03 to determine their lung function trajectory: 72 had persistent PRISm trajectory, 76 normal-to-PRISm trajectory, 155 PRISm-to-normal trajectory, and 857 had normal trajectory. [9] We included participants from two general population studies, the Copenhagen City General Population Study and the Copenhagen City Heart Study, to assess contemporary (year 2003–2017) and historical (1976–1983) occupational inhalant hazards. [10] We also studied 13 974 individuals from the Copenhagen City Heart Study recruited in 1976-78. [11] Participants will be matched by sex and age to controls from the Copenhagen General Population Study (CGPS) and the Copenhagen City Heart Study (CCHS). [12] METHODS AND RESULTS This prospective longitudinal study included 4466 participants from the fifth Copenhagen City Heart Study. [13] METHODS AND RESULTS We examined longitudinal changes of the LA between two visits in the Copenhagen City Heart Study (n = 1065). [14] Participants from the Copenhagen City Heart Study examined with echocardiography, including speckle tracking analyses, were included. [15] The study included 621 community-dwelling adults, mean age 75⋅2 ± 6⋅4 years, 58⋅9 % female, who had participated in the Copenhagen City Heart Study follow-up, and undergone interviews regarding food intake (preceding month), oral and general health (xerostomia, taste alterations, diseases, medication, alcohol consumption and smoking), clinical oral examination and measurements of unstimulated and chewing-stimulated whole saliva flow rates. [16] These changes are based on knowledge gained from longitudinal cohorts such as the Copenhagen City Heart Study, ECLIPSE, SPIROMICS and COPDGene, which have shed light on the natural history of the disease and clinical characteristics associated with exacerbations. [17] Using a Mendelian randomisation design, we examined 118,838 individuals from two Copenhagen cohorts, the Copenhagen General Population Study and the Copenhagen City Heart Study, and 440,328 individuals from the MEGASTROKE study. [18] Recent Findings Two observational studies (Cardiovascular Health in Ambulatory Care Research Team [CANHEART] and Copenhagen City Heart Study and the Copenhagen General Population Study [Copenhagen Heart Studies]) of adults without pre-existing ASCVD have shown a significant U-shaped association of HDL-C with all-cause and cause-specific mortality. [19] We included 118,683 white Danes aged ≥ 20 from the Copenhagen General Population Study (2003–2015) and the Copenhagen City Heart Study (1991–94 and 2001–03). [20] 25 on (1) cardiovascular disease outcomes in two large population-based cohorts (Copenhagen City Heart Study and Copenhagen General Population Study, n = 106,018; and UK Biobank, n = 357,426) and additionally in an elderly population at risk for cardiovascular disease (n = 5241), and on (2) atherosclerotic plaque phenotypes in samples of patients who underwent endarterectomy (n = 1439). [21] These results were validated independently in the Copenhagen City Heart Study cohort. [22] METHODS AND RESULTS We performed 2DSTE analysis of 1997 members of the general population from the fifth round of the Copenhagen City Heart Study, who were free of cardiovascular disease and risk factors. [23] Participants from the 5th round of the Copenhagen City Heart Study, aged < 65 years old, answering a questionnaire regarding occupational physical activity, heavy occupational lifting, use of anti-hypertensive and heart medication, and data on blood pressure, cardiac structure and function, from an echocardiographic examination, were included. [24] DESIGN AND SETTING From the Danish general population, we studied 106,703 and 16,032 individuals in the Copenhagen General Population Study(CGPS) and the Copenhagen City Heart Study(CCHS) with median follow-up of respectively 9 and 32 years. [25] METHODS As part of the prospective Copenhagen City Heart Study, 8697 healthy adults completed a comprehensive questionnaire about leisure-time sports activities. [26] We used a Mendelian randomisation (MR) design in the China Kadoorie Biobank, the Copenhagen City Heart Study, and the Copenhagen General Population Study. [27] Methods: We included 112,457 nondiabetic individuals from the Copenhagen City Heart Study and the Copenhagen General Population Study and assessed their prospective risk of retinopathy, neuropathy, diabetic nephropathy, peripheral arterial disease (PAD), and myocardial infarction (MI) as a function of increasing glucose levels. [28] In the fifth examination of the Copenhagen City Heart Study, 2335 individuals gave consent to wear accelerometers (skin-attached; right thigh and iliac crest; 24 h/day, 7 consecutive days) of which 1670 fulfilled our inclusion criteria (≥16 h/day for ≥5 days; median wear time: 23. [29] METHODS AND RESULTS Characterization of the INSIG2 locus was followed by studies in over 107 000 individuals from the general population, the Copenhagen General Population Study and the Copenhagen City Heart Study, for associations of genetic variants with plasma lipids levels, with risk of myocardial infarction (MI) and with cardiovascular mortality. [30] Population and methods The study population included 6,740 individuals attending the 3rd cycle in 1991–94 of the Copenhagen City Heart Study, providing information on BMI, educational level, health behaviours, well-being, weight half-a-year earlier, and answers to four BWC questions about caring for body weight, assumed benefit of weight loss, current and past slimming experiences. [31] Methods This prospective study includes a total of 78 936 participants from the Copenhagen City Heart Study and the Copenhagen General Population Study, all without previous thromboembolic events and aged <65 years. [32] METHODS We used data from 6,807 participants attending the third survey of the Copenhagen City Heart Study in 1991-1994. [33] Methods Data from the third, fourth and fifth examinations of the Copenhagen City Heart Study were included. [34] (2) have examined the relationship between HDL-C concentrations and the risk of development of autoimmune disease in 2 population-based cohort studies—the Copenhagen General Population Study and the Copenhagen City Heart Study—that included 117341 individuals with baseline HDL-C measurements. [35] 923 individuals with COPD diagnosed similarly in the Copenhagen City Heart Study (CCHS) were used for replication analyses. [36] METHODS A total of 109,566 individuals from the Copenhagen General Population Study and the Copenhagen City Heart Study were genotyped for PCSK9 R46L (rs11591147), R237W (rs148195424), I474V (rs562556), and E670G (rs505151). [37] The Paris Prospective Study, the Lipid Research Clinics Follow-up Study, the Reykjavik study, and the European Prospective Investigation of Cancer (EPIC Norfolk) study showed a relationship between TG levels and CVD, while the Multiple Risk Factor Intervention Trial, the Copenhagen City Heart Study, the Copenhagen General Population Study and the Women’s Health Study found an even stronger relationship between non-fasting TG levels and CVD; as most people eat regularly throughout the day, non-fasting lipids may be a better indicator of mean lipid concentrations in the blood, and individuals are exposed to post-prandial TG most of the time. [38] METHODS From the Copenhagen General Population Study and the Copenhagen City Heart Study, 117865 men and women 20-100+ years of age with measurements of nonfasting plasma triglycerides at baseline were followed prospectively for development of acute pancreatitis. [39] Methods We undertook prospective studies of 2 cohorts enrolled in 1976 to 1978 (13,567 participants from the Copenhagen City Heart Study) and 2003 to 2015 (107,040 participants from the Copenhagen General Population Study). [40] METHODS We examined the association of plasma ferritin concentrations with risk of atrial fibrillation and heart failure in metaanalyses of 35799 men and women from 3 studies of the Danish general population: the Copenhagen City Heart Study, the Danish General Suburban Population Study, and the Copenhagen General Population Study. [41] Methods: Leukocyte TL was measured after diagnosis in 807 patients with non–small cell lung cancer (NSCLC) from the Princess Margaret Cancer Center in Toronto and assessed prospectively in 767 NSCLC cases from the Copenhagen City Heart Study and the Copenhagen General Population Study. [42] DESIGN We included 118,085 individuals from two prospective cohort studies, the Copenhagen City Heart Study and the Copenhagen General Population Study, with BMI measured at baseline. [43] METHODS From 2 studies of the general population-the Copenhagen General Population Study and the Copenhagen City Heart study-we included 107954 and 9387 individuals with baseline measurements of HDL cholesterol. [44] We also studied 1115 individuals with CVD from the CCHS (Copenhagen City Heart Study; 1991-1994) and the CIHDS (Copenhagen Ischemic Heart Disease Study; 1991-1993). [45] 8 9 Using data from individuals with COPD in the Copenhagen General Population Study (n=5262) and the Copenhagen City Heart Study (n=923), Ingebrigtsen et al tested the association of β2 adrenergic receptor polymorphisms Gly16Arg (rs1042713, c. [46]

city heart rhythm

Methods: A retrospective cohort analysis was performed on SARS-CoV-2 positive patients with AD at Columbia University Medical Center and Kansas City Heart Rhythm Institute. [1] David’sMedical Center, Austin, Texas, USA 6 Kansas City Heart Rhythm Institute and Research Foundation, Kansas City, Kansas, USA. [2]