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Methods To assess the role of Sdc1 in breast cancer metastasis, we silenced Sdc1 expression in the triple-negative breast cancer human MDA-MB-231 cell line and overexpressed it in the mouse mammary carcinoma 4T1 cell line.
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To assess the role of Sdc1 in breast cancer metastasis, we silenced Sdc1 expression in the triple-negative breast cancer human MDA-MB-231 cell line and overexpressed it in the mouse mammary carcinoma 4T1 cell line.
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Methods To assess the role of Sdc1 in breast cancer metastasis, we silenced Sdc1 expression in the triple-negative breast cancer human MDA-MB-231 cell line and overexpressed it in the mouse mammary carcinoma 4T1 cell line.
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To assess the role of Sdc1 in breast cancer metastasis, we silenced Sdc1 expression in the triple-negative breast cancer human MDA-MB-231 cell line and overexpressed it in the mouse mammary carcinoma 4T1 cell line.
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These strategies could also reduce the impacts on water scarcity by 84%, freshwater eutrophication by 57%, cancer human health effects by at least 30%, and land use by 3%.
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Highlights of this study are: 1) The approaches presented here deal with the amalgamation of probability distributions where representations of parameters are of bell shaped fuzzy numbers (BFNs)/FNs; fuzzy numbers (FNs) of various types and shapes plus DSS with fuzzy focal elements of different types within the same framework; 2) Non-cancer human health risk assessment is carried out in this setting and 3) Risk values are obtained in the form of FNs at different fractiles.
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The analysis indicates that even histo-pathologically equally graded cancer nodules from the same tumor have substantially different transcriptomic organizations, raising legitimate questions about the validity of meta-analyses comparing large populations of healthy and cancer humans.
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