Introduction to Cancer Gc
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We also investigated possible mechanisms for which the loss of trans- co-expression emerges in cancer GCN.
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QUESTION ASKED
How much downstream revenue do cancer genetic counselors (GCs) generate when they identify patients with hereditary breast and ovarian cancer (HBOC) (BRCA1/BRCA2) and Lynch syndrome (LS) pathogenic variants?
SUMMARY ANSWER
Over a 10-year period, the downstream revenue generated from cancer GCs' identification of patients with HBOC and LS was $32.
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We compared the number of intra-chromosome (cis-) and inter-chromosome (trans-) co-expression interactions in normal and cancer GCNs.
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By RNA-seq, immunohistochemical staining (IHC), Western blot and luciferase reporter assay, we identified and confirmed EGFL7 as a direct functional target of miR-126 in cancer GCs.
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