Introduction to Behaviour Alteration
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Toxoplasma infection exhibited variable consequences ranging from aborted to hard infections, in addition to modifications cytokines, change gene expression, and behaviour alterations.
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Among other parasites that parasitise crustaceans, parasitic barnacles (Rhizocephala) are considered the most intriguing, both in terms of their unique life cycle and the detrimental changes they induced upon their hosts such as host sterilisation, moult inhibition (anecdysis), growth reduction, feminisation of male individuals, and behaviour alteration.
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[1] Severe deficiency of HGPRT in Grade-4 LN syndrome leads to the accumulation of uric acid crystals in different organs and is characterised by acute generalised dystonia, behaviour alterations such as self-aggression, seizures and cognitive impairment and therefore presents with multiple anaesthetic challenges.
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Although NLC-DOX-SC and free DOX:SC, at the synergistic molar ratio, showed similar activity in the in vivo study, the free combination provoked body weight loss, behaviour alterations and haematological toxicity in the animals, while this was not observed for NLC-DOX-SC.
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