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Tyrosine Kinases sentence examples within epidermal growth factor



Pre-existing Cell States Control Heterogeneity of Both EGFR and CXCR4 Signaling


Nasopharyngeal Carcinoma: The Role of the EGFR in Epstein–Barr Virus Infection

Tyrosine Kinases sentence examples within protein tyrosine phosphatase



The phosphatase Shp1 interacts with and dephosphorylates cortactin to inhibit invadopodia function


PD-1 Regulates Passive Anaphylaxis: A Possible Role of the Mast Cell Intracellular Inhibitory Signal

Tyrosine Kinases sentence examples within tyrosine kinase inhibitor



Control of renal cell carcinoma brain metastases with cabozantinib following progression on immune checkpoint inhibitor therapy


Direct interaction of the ATP-sensitive K+ channel by the tyrosine kinase inhibitors imatinib, sunitinib and nilotinib.



Tyrosine Kinases sentence examples within mitogen activated protein



Comprehensive analysis of oncogenic fusions in mismatch repair deficient colorectal carcinomas by sequential DNA and RNA next generation sequencing


Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition

Tyrosine Kinases sentence examples within vascular endothelial growth



Regulation of VEGFR Signalling in Lymphatic Vascular Development and Disease: An Update


[Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Contributes to Tamoxifen Resistance in Estrogen-Positive Breast Cancer Patients].

Tyrosine Kinases sentence examples within small molecule inhibitor



Effects of CYP3A inhibitor ketoconazole, voriconazole, and itraconazole on the pharmacokinetics of sunitinib and its main metabolite in rats.


Pursuing Precision: Receptor Tyrosine Kinase Inhibitors for Treatment of Pediatric Solid Tumors

Tyrosine Kinases sentence examples within platelet derived growth



Clinical efficacy comparison of avapritinib with other tyrosine kinase inhibitors in gastrointestinal stromal tumors with PDGFRA D842V mutation: a retrospective analysis of clinical trial and real-world data


P033 Scleroderma-like fibrotic disorder associated with a gastro-intestinal stromal tumour which responded only to imatinib

Tyrosine Kinases sentence examples within fibroblast growth factor



Abstract 1080: Altered response to BET-bromodomain inhibitors JQ1 and I-BET-762 targeting c-Myc in erdafitinib-resistant endometrial carcinoma cell line AN3 CA


Evaluation of the pharmacokinetics of pemigatinib in patients with impaired hepatic or renal function.

Tyrosine Kinases sentence examples within oral small molecule



Identification and characterization of in vitro, in vivo, and reactive metabolites of tandutinib using liquid chromatography ion trap mass spectrometry.


Efficacy and safety of anlotinib in patients with advanced malignancy: a single-center, single-arm, phase 2 trial

Tyrosine Kinases sentence examples within cell proliferation differentiation



[Roles of growth factors on vascular remodeling in pulmonary hypertension].


Role of receptor tyrosine kinases mediated signal transduction pathways in tumor growth and angiogenesis-New insight and futuristic vision.

Tyrosine Kinases sentence examples within receptor tyrosine kinase



The Caveolin-1 Scaffolding Domain Peptide Reverses Aging-Associated Deleterious Changes in Multiple Organs


A canine case of malignant melanoma carrying a KIT c.1725_1733del mutation treated with toceranib: a case report and in vitro analysis

Tyrosine Kinases sentence examples within human epidermal growth



HER Tyrosine Kinase Family and Rhabdomyosarcoma: Role in Onset and Targeted Therapy


The Molecular Mechanisms of Cardiotoxicity Induced by HER2, VEGF, and Tyrosine Kinase Inhibitors: an Updated Review

Tyrosine Kinases sentence examples within growth factor receptor



Avapritinib in Patients With Advanced Gastrointestinal Stromal Tumors Following at Least Three Prior Lines of Therapy


Highlights on Selected Growth Factors and their Receptors as Promising Anticancer Drug Targets.

Tyrosine Kinases sentence examples within neurotrophic tyrosine receptor



The European Medicines Agency review of entrectinib for the treatment of adult or paediatric patients with solid tumours who have a neurotrophic tyrosine receptor kinase gene fusions and adult patients with non-small-cell lung cancer harbouring ROS1 rearrangements


Entrectinib: A Review in NTRK+ Solid Tumours and ROS1+ NSCLC

Tyrosine Kinases sentence examples within anaplastic lymphoma kinase



Loss of RET Promotes Mesenchymal Identity in Neuroblastoma Cells


Coordination among multiple receptor tyrosine kinase signals controls Drosophila developmental timing and body size

Tyrosine Kinases sentence examples within cell survival proliferation



Discovery of a potent and selective Axl inhibitor in preclinical model.


The Akt-mTORC1 pathway mediates Axl receptor tyrosine kinase-induced mesangial cell proliferation.

Tyrosine Kinases sentence examples within potent inhibitory activity



Quinazolin-4(3H)-one based potential multiple tyrosine kinase inhibitors with excellent cytotoxicity


Synthesis, characterization, biological evaluation and molecular docking of a new quinazolinone-based derivative as a potent dual inhibitor for VEGFR-2 and EGFR tyrosine kinases.

Tyrosine Kinases sentence examples within proliferation differentiation migration



Role of co- and post-translational modifications of SFKs in their kinase activation

Tyrosine Kinases sentence examples within 3 substituted indolin



The development of 3-substituted indolin-2-one derivatives as kinase inhibitors for cancer therapy.

Tyrosine Kinases sentence examples within activated protein kinase



Oximes: Novel Therapeutics with Anticancer and Anti-Inflammatory Potential

Tyrosine Kinases sentence examples within Receptor Tyrosine Kinases



Primary ciliary signaling: links with the cell cycle.


Antibody-mediated depletion of CCR10+EphA3+ cells ameliorates fibrosis in IPF

Tyrosine Kinases sentence examples within Protein Tyrosine Kinases



Regulation of Fibroblast Cell Polarity by Src Tyrosine Kinase


The Mitochondria-Independent Cytotoxic Effect of Leflunomide on RPMI-8226 Multiple Myeloma Cell Line

Tyrosine Kinases sentence examples within Multiple Tyrosine Kinases



The Oncogenic Signaling Disruptor, NDRG1: Molecular and Cellular Mechanisms of Activity


Control of renal cell carcinoma brain metastases with cabozantinib following progression on immune checkpoint inhibitor therapy

Tyrosine Kinases sentence examples within Family Tyrosine Kinases



Src-mediated tyrosine phosphorylation of PRC1 and kinastrin/SKAP on the mitotic spindle


Differences in the dynamics of the tandem-SH2 modules of the Syk and ZAP-70 tyrosine kinases.

Tyrosine Kinases sentence examples within Nonreceptor Tyrosine Kinases



Roles of adenosine A1 receptors in the regulation of SFK activity in the rat forebrain


The Caveolin-1 Scaffolding Domain Peptide Reverses Aging-Associated Deleterious Changes in Multiple Organs

Tyrosine Kinases sentence examples within Inhibit Tyrosine Kinases



Tyrosine Kinase Inhibitor Family of Drugs as Prospective Targeted Therapy for COVID-19 Based on In Silico And 3D-Human Vascular Lung Model Studies


Dispirooxindole-pyrrolothiazoles: Synthesis, anti-cancer activity, molecular docking and green chemistry metrics evaluation

Tyrosine Kinases sentence examples within Associated Tyrosine Kinases



TLR4-Mediated Recognition of Mouse Polyomavirus Promotes Cancer-Associated Fibroblast-Like Phenotype and Cell Invasiveness


JAK3 Is Expressed in the Nucleus of Malignant T Cells in Cutaneous T Cell Lymphoma (CTCL)

Tyrosine Kinases sentence examples within Src Tyrosine Kinases



Identification of novel allosteric binding sites and multi-targeted allosteric inhibitors of receptor and non-receptor tyrosine kinases using a computational approach.


c-Src regulates Nrf2 activity through PKCδ after oxidant stimulus.

Tyrosine Kinases sentence examples within Targeted Tyrosine Kinases



Polydatin reduces cardiotoxicity of tyrosine kinase inhibitor sunitinib by decreasing pro-oxidative stress, pro-inflammatory cytokines and NLRP3 inflammasome expression.


Polydatin Reduces Cardiotoxicity and Enhances the Anticancer Effects of Sunitinib by Decreasing Pro-Oxidative Stress, Pro-Inflammatory Cytokines, and NLRP3 Inflammasome Expression

Tyrosine Kinases sentence examples within Egfr Tyrosine Kinases



Quinazolin-4(3H)-one based potential multiple tyrosine kinase inhibitors with excellent cytotoxicity


Synthesis, characterization, biological evaluation and molecular docking of a new quinazolinone-based derivative as a potent dual inhibitor for VEGFR-2 and EGFR tyrosine kinases.

Tyrosine Kinases sentence examples within Oncogenic Tyrosine Kinases



TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors


Discovery of novel p90 ribosomal S6 kinase 2 inhibitors for potential cancer treatment through ligand-based and structure-based virtual screening methods

Tyrosine Kinases sentence examples within Bacterial Tyrosine Kinases



A Conserved Structural Role for the Walker-A Lysine in P-Loop Containing Kinases


Bacterial Protein Kinases.

Tyrosine Kinases sentence examples within Target Tyrosine Kinases



109. The effectiveness of systemic therapies after surgery for metastatic renal cell carcinoma to the spine: a propensity analysis controlling for sarcopenia, frailty, and nutrition


The effectiveness of systemic therapies after surgery for metastatic renal cell carcinoma to the spine: a propensity analysis controlling for sarcopenia, frailty, and nutrition.

Tyrosine Kinases sentence examples within Several Tyrosine Kinases



A canine case of malignant melanoma carrying a KIT c.1725_1733del mutation treated with toceranib: a case report and in vitro analysis


Effects of tyrosine kinase inhibitors on thyroid function and thyroid hormone metabolism.

Tyrosine Kinases sentence examples within Type Tyrosine Kinases



Suppression of epithelial abnormalities by nintedanib in induced-rheumatoid arthritis-associated interstitial lung disease mouse model


[Analysis of Target Molecules towards Anti-cancer Therapeutic Antibodies].

Tyrosine Kinases sentence examples within tyrosine kinases inhibitor



Polydatin reduces cardiotoxicity of tyrosine kinase inhibitor sunitinib by decreasing pro-oxidative stress, pro-inflammatory cytokines and NLRP3 inflammasome expression.


The development of 3-substituted indolin-2-one derivatives as kinase inhibitors for cancer therapy.

Tyrosine Kinases sentence examples within tyrosine kinases involved



Src and Fyn regulation of NMDA receptors in health and disease


Case Report: Reversal of Long-Standing Refractory Diffuse Non-Scarring Alopecia Due to Systemic Lupus Erythematosus Following Treatment With Tofacitinib

Tyrosine Kinases sentence examples within tyrosine kinases play



Allosteric Regulation of the EphA2 Receptor Intracellular Region by Serine/Threonine Kinases


Imatinib (STI571) Inhibits the Expression of Angiotensin-Converting Enzyme 2 and Cell Entry of the SARS-CoV-2-Derived Pseudotyped Viral Particles

Tyrosine Kinases sentence examples within tyrosine kinases axl



Phagocytosis promotes plaque


The Akt-mTORC1 pathway mediates Axl receptor tyrosine kinase-induced mesangial cell proliferation.

Tyrosine Kinases sentence examples within tyrosine kinases receptor



Synthesis, spectral characterization, DFT calculations, pharmacological studies, CT-DNA binding and molecular docking of potential N, O-multidentate chelating ligand and its VO(II), Zn(II) and ZrO(II) chelates.


A review on the role of different ephrins in glioma.

Tyrosine Kinases sentence examples within tyrosine kinases may



Transcriptome analysis of ovary tissues from low- and high-yielding Changshun green-shell laying hens


Janus Kinase Signaling: Oncogenic Criminal of Lymphoid Cancers

Tyrosine Kinases sentence examples within tyrosine kinases c



Multi-component Reactions of Cyclohexan-1,3-diketones to Produce Fused Pyran Derivatives with Antiproliferative Activities and Tyrosine Kinases and Pim-1 Kinase Inhibitions.


The Caveolin-1 Scaffolding Domain Peptide Reverses Aging-Associated Deleterious Changes in Multiple Organs

Tyrosine Kinases sentence examples within tyrosine kinases trka



Targeting TRK: A Fast-Tracked Application of Precision Oncology and Future Directions.


The European Medicines Agency review of entrectinib for the treatment of adult or paediatric patients with solid tumours who have a neurotrophic tyrosine receptor kinase gene fusions and adult patients with non-small-cell lung cancer harbouring ROS1 rearrangements

Tyrosine Kinases sentence examples within tyrosine kinases important



JAK inhibitors, psoriatic arthritis, and axial spondyloarthritis: a critical review of clinical trials


XB130 deficiency enhances carcinogen-induced skin tumorigenesis.

Tyrosine Kinases sentence examples within tyrosine kinases kit



LncRNA PVT1 promotes cells proliferation via PI3K–AKT–mTOR Pathway in gastrointestinal stromal tumor


Screening of clustered regulatory elements reveals functional cooperating dependencies in Leukemia

Tyrosine Kinases sentence examples within tyrosine kinases triggered



Atiprimod Triggered Apoptotic Cell Death via Acting on PERK/eIF2a/ATF4/CHOP and STAT3/NF-KB axis in MDA-MB-231 and MDA-MB-468 Breast Cancer Cells


Atiprimod triggered apoptotic cell death via acting on PERK/eIF2α/ATF4/CHOP and STAT3/NF-ΚB axis in MDA-MB-231 and MDA-MB-468 breast cancer cells.

Tyrosine Kinases sentence examples within tyrosine kinases showed



Regorafenib in recurrent glioblastoma patients: A large real-life experience.


Functional analysis of isoflavones using patient-derived human colonic organoids.

Tyrosine Kinases sentence examples within tyrosine kinases regulate



Receptor tyrosine kinase inhibitors for the treatment of osteosarcoma and Ewing sarcoma


Visualization of Host Cell Kinase Activation by Viral Proteins Using GFP Fluorescence Complementation and Immunofluorescence Microscopy.


Src/lck inhibitor dasatinib reversibly switches off cytokine release and T cell cytotoxicity following stimulation with T cell bispecific antibodies



Protein tyrosine phosphatome metabolic screen identifies TC‐PTP as a positive regulator of cancer cell bioenergetics and mitochondrial dynamics



GPR68 Contributes to Persistent Acidosis-Induced Activation of AGC Kinases and Tyrosine Phosphorylation in Organotypic Hippocampal Slices



Editorial: structure–function relationships of tyrosine kinase- and tyrosine phosphatase-linked receptors in platelets and megakaryocytes


Tyrosine Kinases 티로신 키나제


Tyrosine Kinases 티로신 키나제
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