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Development of topical Thymoquinone loaded polymer-lipid hybrid vesicular gel: in-vitro and ex-vivo evaluation.


Zeylenone synergizes with cisplatin in osteosarcoma by enhancing DNA damage, apoptosis, and necrosis via the Hsp90/AKT/GSK3β and Fanconi anaemia pathway

Toxicity Toward sentence examples within human cancer cell



Binding of RuCp complexes with human apo-transferrin: fluorescence spectroscopy and molecular docking methods.


In vitro cytotoxicity of cardamom oil, lemon oil, and jasmine oil on human skin, gastric, and brain cancer cell line

Toxicity Toward sentence examples within human breast cancer



Novel luminescent benzopyranothiophene- and BODIPY-derived aroylhydrazonic ligands and their dicopper(II) complexes: syntheses, antiproliferative activity and cellular uptake studies.


Investigation of DNA/BSA binding and cytotoxic properties of new Co(II), Ni(II) and Cu(II) hydrazone complexes



Toxicity Toward sentence examples within normal cell line



One-step approach of dual-responsive prodrug nanogels via Diels-Alder reaction for drug delivery


Synthesis and antitumor activity of novel alkynyl (phosphine) digold(I) complexes

Toxicity Toward sentence examples within human lung cancer



Novel green synthesis of silver nanoparticles mediated by Curcumae kwangsiensis for anti-lung cancer activities: a preclinical trial study


Design, synthesis, biological activities and 3D-QSAR studies of quinazolinone derivatives containing hydrazone structural units

Toxicity Toward sentence examples within 231 breast cancer



The effect of deoxyfluorination and O-acylation on the cytotoxicity of N-acetyl-D-gluco- and D-galactosamine hemiacetals.


Cellulose Nanocrystals/Chitosan-Based Nanosystems: Synthesis, Characterization, and Cellular Uptake on Breast Cancer Cells

Toxicity Toward sentence examples within cell lines without



Anti-human lung cancer activities and survey of gluthation reductase and gluthation S transferase inhibition properties with molecular modeling studies of 2′-Hydroxy-5′-methyl-3′-nitroacetophenone: A pre-clinical trial study

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Turmeric Oil Mediated Green Synthesis of Silver Nanoparticles and their Antioxidant Activity


Antiadhesive Properties of Imidazolium Ionic Liquids Based on (−)-Menthol Against Candida spp.

Toxicity Toward sentence examples within Acute Toxicity Toward



Multi-residue analysis of pharmaceuticals in water samples by liquid chromatography- mass spectrometry: Quality assessment and application to the risk assessment of urban-influenced surface waters in a metropolitan area of Central America


Benfuresate induces developmental toxicity in zebrafish larvae by generating apoptosis and pathological modifications.

Toxicity Toward sentence examples within Potential Toxicity Toward



Diclofenac Degradation by Radiocatalysis


5-Benzyliden-2-(5-methylthiazol-2-ylimino)thiazolidin-4-ones as Antimicrobial Agents. Design, Synthesis, Biological Evaluation and Molecular Docking Studies

Toxicity Toward sentence examples within Selective Toxicity Toward



Toxicity and membrane perturbation properties of the ribotoxin-like protein Ageritin.


Enzyme-mediated backbone N-methylation in ribosomally encoded peptides.

Toxicity Toward sentence examples within Significant Toxicity Toward



Chemical Composition, Antibacterial Screening and Cytotoxic Activity of Chiliadenus antiatlanticus (Asteraceae) Essential Oil


Nutritional composition, biological activities, and cytotoxicity of the underutilized fruit of Eleiodoxa conferta

Toxicity Toward sentence examples within Higher Toxicity Toward



Characterization of pH-sensitive chitosan/hydroxypropyl methylcellulose composite nanoparticles for delivery of melatonin in cancer therapy


Assessment of the risk posed by three antifouling biocides to Pacific oyster embryos and larvae in Hiroshima Bay, Japan

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In vitro evaluations of biomolecular interactions, antioxidant and anticancer activities of Nickel(II) and Copper(II) complexes with 1:2 coordination of anthracenyl hydrazone ligands


A Dual-Specificity Inhibitor Targets Polyphosphate Kinase 1 and 2 Enzymes To Attenuate Virulence of Pseudomonas aeruginosa

Toxicity Toward sentence examples within High Toxicity Toward



Identification and efficacy of active metabolites of pomegranate fruit peel aqueous extract against sucking pests of rose and their predators


Anticancer Activity and High Content Screening of New 6-Substituted-5,6-dihydrobenzo[4,5]imidazo[1,2-c]quinazoline Derivatives

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Towards prevention of biofilm formation: Ti6Al7Nb modified with nanocomposite layers of chitosan and Ag/Au nanoparticles


Targeting DNA Damage Repair Functions of Two Histone Deacetylases, HDAC8 and SIRT6, Sensitizes Acute Myeloid Leukemia to NAMPT Inhibition

Toxicity Toward sentence examples within Reduced Toxicity Toward



Optimization and Development of Selective Histone Deacetylase Inhibitor (MPT0B291)-Loaded Albumin Nanoparticles for Anticancer Therapy


Removal of methyl orange from aqueous solution using SRB supported Bio-Pd/Fe NPs

Toxicity Toward sentence examples within Les Toxicity Toward



Qizhen capsule inhibits colorectal cancer by inducing NAG-1/GDF15 expression that mediated via MAPK/ERK activation.


Targeted Gold Nanohybrids Functionalized with Folate-Hydrophobic-Quaternized Pullulan Delivering Camptothecin for Enhancing Hydrophobic Anticancer Drug Efficacy

Toxicity Toward sentence examples within Lower Toxicity Toward



Trigger of Apoptosis in Adenocarcinoma Gastric Cell Line (AGS) by a Complex of Thiosemicarbazone and Copper Nanoparticles


Advanced oxidation processes of coumarins by hydroperoxyl radical: An experimental and theoretical study, and ecotoxicology assessment

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Free spermidine evokes superoxide radicals that manifest toxicity


Pancreatic cancer and immune checkpoint inhibitors-still a long way to go.

Toxicity Toward sentence examples within Exhibited Toxicity Toward



HGG-33. EXPLOITING METABOLIC DEFECTS WITH NAMPT INHIBITORS IN DIPG


Emerging marine derived nanohydroxyapatite and their composites for implant and biomedical applications.

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Evaluation of a Keratin 1 Targeting Peptide-Doxorubicin Conjugate in a Mouse Model of Triple-Negative Breast Cancer


Ribonuclease zymogen induces cytotoxicity upon HIV-1 infection

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Ag0 decorated Cr2S3 NPs embedded on PVP matrix: A colorimetric probe for selective and rapid detection of sulphide ions from environmental samples.


Effects of metal nanoparticle-mediated treatment on seed quality parameters of different crops.

Toxicity Toward sentence examples within Moderate Toxicity Toward



New pectin derivatives with antimicrobial and emulsification properties via complexation with metal-terpyridines.


1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity.

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A probabilistic model for assessing uncertainty and sensitivity in the prediction of monochloramine loss in French river waters.


Multifunctional growth of dendritic magnetic nanocarrier for targeted drug delivery

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Petasin potently inhibits mitochondrial complex I–based metabolism that supports tumor growth and metastasis


Design, synthesis, biological activities and 3D-QSAR studies of quinazolinone derivatives containing hydrazone structural units

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Cadmium toxicity: A role in bone cell function and teeth development.


Cadmium, silicon and nutrient accumulation by maize plants grown on a contaminated soil amended with a diatomaceous Earth fertilizer

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Hsp70-containing Extracellular Vesicles are Capable of Activating of Adaptive Immunity in Models of Mouse Melanoma and Colon Carcinoma


In vitro studies of Pluronic F127 coated magnetic silica nanocarriers for drug delivery system targeting liver cancer

Toxicity Toward sentence examples within Greater Toxicity Toward



Ecotoxicological effects of microplastics on aquatic organisms: a review


Effect of root surface charge on the absorption and accumulation of Cu(II) by different japonica and indica rice varieties under acidic conditions.

Toxicity Toward sentence examples within Cellular Toxicity Toward



A cyclic lipopeptide surfactin is a species-selective Hsp90 inhibitor that suppresses cyanobacterial growth.


Hemostatic and antibacterial PVA/Kaolin composite sponges loaded with penicillin–streptomycin for wound dressing applications

Toxicity Toward sentence examples within Systemic Toxicity Toward



Metal complexes of β-carboline: Advances in anticancer therapeutics


Novel Cu-LDH-based nanomedicine for combination cancer therapy

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A New Look at the Purported Health Benefits of Commercial and Natural Clays


Bioguided Isolation of Active Compounds from Rhamnus alaternus against Methicillin-Resistant Staphylococcus aureus (MRSA) and Panton-Valentine Leucocidin Positive Strains (MSSA-PVL)

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Design cytotoxicity: The effect of silver nanoparticles stabilized by selected antioxidants on melanoma cells.


Design, synthesis, and physicochemical characterization of new aminothiohydantoin Schiff base complexes for cancer chemotherapy

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Chronic toxicity of polystyrene nanoparticles in the marine mussel Mytilus galloprovincialis.


Biogenic synthesis of novel platinum-palladium bimetallic nanoparticles from aqueous Annona muricata leaf extract for catalytic activity

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Baicalin Inhibits Ferroptosis in Intracerebral Hemorrhage


In vitro effects of Harmine against Echinococcus granulosus protoscoleces by stimulating DNA damage.

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Optimization and Development of Selective Histone Deacetylase Inhibitor (MPT0B291)-Loaded Albumin Nanoparticles for Anticancer Therapy


Qizhen capsule inhibits colorectal cancer by inducing NAG-1/GDF15 expression that mediated via MAPK/ERK activation.

Toxicity Toward sentence examples within toxicity toward human



Design and Selection of Engineered Lytic Proteins With Staphylococcus aureus Decolonizing Activity


On the rapid in situ oxidation of two-dimensional V2CTz MXene in culture cell media and their cytotoxicity.

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Polyethylenimine-modified graphitic carbon nitride nanosheets: a label-free Raman traceable siRNA delivery system.


Effect of cabazitaxel on macrophages improves CD47-targeted immunotherapy for triple-negative breast cancer

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Nontoxic Antimicrobial Cationic Peptide Nanoconstructs with Bacteria-Displaceable Polymeric Counteranions.


Taxifolin, an Inhibitor of Sortase A, Interferes With the Adhesion of Methicillin-Resistant Staphylococcal aureus

Toxicity Toward sentence examples within toxicity toward mouse



Therapeutic potential of Moringa oleifera seed polysaccharide embedded silver nanoparticles in wound healing.


A Synergistic New Approach Toward Enhanced Antibacterial Efficacy via Antimicrobial Peptide Immobilization on a Nitric Oxide-Releasing Surface.

Toxicity Toward sentence examples within toxicity toward tumor



Metabolic Screening of Cytotoxic T-cell Effector Function Reveals the Role of CRAC Channels in Regulating Lethal Hit Delivery


Integration of Dual Targeting and Dual Therapeutic Modules Endows Self-Assembled Nanoparticles with Anti-Tumor Growth and Metastasis Functions

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Synthesis and spectroscopic properties of 4,4′-bipyridine linker bioactive macrocycle boronate esters: photophysical properties and antimicrobial with antioxidant studies


Synthesis and evaluation of Grateloupia Livida polysaccharides-functionalized selenium nanoparticles.

Toxicity Toward sentence examples within toxicity toward mcf



Lipid/PAA-coated mesoporous silica nanoparticles for dual-pH-responsive codelivery of arsenic trioxide/paclitaxel against breast cancer cells


Synthesis of novel indole-thiazolidinone hybrid structures as promising scaffold with anticancer potential.

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Recent Advances in Preclinical Research Using PAMAM Dendrimers for Cancer Gene Therapy


Calotropis gigantea stem bark extract induced apoptosis related to ROS and ATP production in colon cancer cells

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Bioactivity of Biosilica Obtained From North Atlantic Deep-Sea Sponges


Preparation and characterization of a novel polysialic acid/gelatin composite hydrogels cross-linked by Tannic acid to improve healing and nursing care of cesarean section dressing

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Diffusion of water and protein drug in 1,4-butanediol diglycidyl ether crosslinked galactomannan hydrogels and its correlation with the physicochemical properties.


Cytotoxicity activities and chemical characteristics of exopolysaccharides and intracellular polysaccharides of Physarum polycephalum microplasmodia

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A Method for Liposome Co-encapsulation of Phenethyl Isothiocyanate and Cisplatin and Determining Its Toxicity Against Lung and Lung Cancer Cells.


Disruption of Cytosolic Folate Integrity Aggravates Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and Modulates Metastatic Properties in Non-Small-Cell Lung Cancer Cells

Toxicity Toward sentence examples within toxicity toward caco



Impact of Adding Polysaccharides on the Stability of Egg Yolk/Fish Oil Emulsions under Accelerated Shelf-Life Conditions


PEG-conjugated single-walled carbon nanotubes enhance the cellular uptake of Coenzyme Q10: in vitro evaluation and mechanism study

Toxicity Toward sentence examples within toxicity toward hacat



Polyaniline-Conjugated Boron Nitride Nanoparticles Exhibiting Potent Effects against Pathogenic Brain-Eating Amoebae.


Optimization of Fermentation Process of Pomegranate Peel and Schisandra Chinensis and the Biological Activities of Fermentation Broth: Antioxidant Activity and Protective Effect Against H2O2-induced Oxidative Damage in HaCaT Cells

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A new peptaibol, RK-026A, from the soil fungus Trichoderma sp. RK10-F026 by culture condition-dependent screening.


Zealpeptaibolin, an 11-mer cytotoxic peptaibol group with 3 Aib-Pro motifs isolated from Trichoderma sp. RK10-F026.

Toxicity Toward 독성


Toxicity Toward 독성
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