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Threonine Kinase sentence examples within receptor interacting serine



Selenomethionine alleviates LPS-induced JNK/NLRP3 inflammasome-dependent necroptosis by modulating miR-15a and oxidative stress in chicken lungs.


Targeting the PANoptosome with miRNA Loaded Mesenchymal Stem Cell Derived Extracellular Vesicles; a New Path to Fight Against the Covid-19?

Threonine Kinase sentence examples within mitogen activated protein



A JAK of all trades: how global phosphoproteomics reveal the Achilles heel of MPNs


[Phosphorylation of Smurf2 at Thr249 by Erk5 regulates TGF-β signaling].

Threonine Kinase sentence examples within proto oncogene serine



Multimodality Imaging and Genetics of Primary Mucosal Melanomas and Response to Treatment.


Pulmonary sclerosing pneumocytoma masquerading adenocarcinoma with co-existing BRAF V600E and PTEN mutation.


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Threonine Kinase sentence examples within glycogen synthase kinase



Dysregulation of GSK3β-Target Proteins in Skin Fibroblasts of Myotonic Dystrophy Type 1 (DM1) Patients.


Recent Advances in the Discovery of GSK-3 Inhibitors from Synthetic Origin in the Treatment of Neurological Disorders.

Threonine Kinase sentence examples within phosphatidylinositol 3 kinase



Combined Targeting of AKT and mTOR Synergistically Inhibits Formation of Primary Colorectal Carcinoma Tumouroids In Vitro: A 3D Tumour Model for Pre-therapeutic Drug Screening


Inhibitors of the PI3K/Akt/mTOR Pathway in Prostate Cancer Chemoprevention and Intervention

Threonine Kinase sentence examples within activated protein kinase



Tectorigenin regulates migration, invasion, and apoptosis in dexamethasone-induced human airway epithelial cells through up-regulating miR-222-3p.


TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy.

Threonine Kinase sentence examples within p21 activated kinase



p21-Activated kinase 1 (PAK1) in aging and longevity: An overview


Expression of phosphorylated p21-activated kinase 4 is associated with aggressive histologic characteristics and poor prognosis in patients with surgically treated renal cell carcinoma

Threonine Kinase sentence examples within cyclin dependent kinase



CDK10 in Gastrointestinal Cancers: Dual Roles as a Tumor Suppressor and Oncogene


CDKL5 deficiency disorder in males: Five new variants and review of the literature.

Threonine Kinase sentence examples within ataxia telangiectasia mutated



Vasculogenic Mimicry Formation Predicts Tumor Progression in Oligodendroglioma


UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma.

Threonine Kinase sentence examples within extracellular signal regulated



RSK1 vs. RSK2 Inhibitory Activity of the Marine β-Carboline Alkaloid Manzamine A: A Biochemical, Cervical Cancer Protein Expression, and Computational Study


Вовлечение ERK MAPK каскада в формирование спаечного процесса в брюшной полости

Threonine Kinase sentence examples within microtubule associated serine



Pathogenic MAST3 variants in the STK domain are associated with epilepsy


A rare coding mutation in the MAST2 gene causes venous thrombosis in a French family with unexplained thrombophilia: The Breizh MAST2 Arg89Gln variant

Threonine Kinase sentence examples within epidermal growth factor



How autophagy controls the intestinal epithelial barrier.


Pembrolizumab as a monotherapy or in combination with platinum-based chemotherapy in advanced non-small cell lung cancer with PD-L1 tumor proportion score (TPS) ≥50%: real-world data

Threonine Kinase sentence examples within interacting protein kinase



Prostate cancer-associated SPOP mutations lead to genomic instability through disruption of the SPOP–HIPK2 axis


Phenotypic Effects of Homeodomain-Interacting Protein Kinase 2 Deletion in Mice

Threonine Kinase sentence examples within receptor associated protein



FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis


Serine-Threonine Kinase Receptor-Associated Protein (STRAP) Knockout Decreases the Malignant Phenotype in Neuroblastoma Cell Lines

Threonine Kinase sentence examples within transforming growth factor



The Biological Function of TUSC7/miR-1224-3p Axis in Triple-Negative Breast Cancer


Potential effect of adrenomedullin on metabolic and endocrinal dysfunctions in the experimentally induced polycystic ovary: Targeting implication of endoplasmic reticulum stress

Threonine Kinase sentence examples within associated coiled coil



Perspectives on ROCK2 as a Therapeutic Target for Alzheimer’s Disease


Role of RhoA/ROCK signaling in Alzheimer’s disease

Threonine Kinase sentence examples within mitotic checkpoint serine



Adventures of the undead at kinetochores


Weighted genes associated with the progression of retinoblastoma: Evidence from bioinformatic analysis.

Threonine Kinase sentence examples within kinase interacting serine



Targeting of MNK/eIF4E overcomes chemoresistance in cervical cancer.


MKNK2 enhances chemoresistance of ovarian cancer by suppressing autophagy via miR-125b.

Threonine Kinase sentence examples within microtubule associated protein



Microtubule affinity regulating kinase 4: A promising target in the pathogenesis of atherosclerosis.


Autophagy and Mitophagy Promotion in a Rat Model of Endometriosis

Threonine Kinase sentence examples within cell cycle progression



Dominant monoallelic variant in the PAK2 gene causes Knobloch syndrome type 2.


Co-Targeting PIM Kinase and PI3K/mTOR in NSCLC

Threonine Kinase sentence examples within rare autosomal recessive



Evidence for pathogenicity of variant ATM Val1729Leu in a family with ataxia telangiectasia


A Novel STK4 Mutation Impairs T Cell Immunity Through Dysregulation of Cytokine-Induced Adhesion and Chemotaxis Genes.

Threonine Kinase sentence examples within related kinase 2



Vaccinia-related kinase 2 drives pancreatic cancer progression by protecting Plk1 from Chfr-mediated degradation


Study of mangal based naphthoquinone derivatives anticancer potential towards chemo-resistance related Never in mitosis gene A-related kinase 2-Insilico approach

Threonine Kinase sentence examples within progenitor kinase 1



Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds.


Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1

Threonine Kinase sentence examples within tumor necrosis factor



Transcriptome and Function of Novel Immunosuppressive Autoreactive Invariant Natural Killer T Cells That Are Absent in Progressive Multiple Sclerosis


A Novel atTAK Against Hepatocellular Carcinoma: Overcoming Resistance to Sorafenib

Threonine Kinase sentence examples within receptor tyrosine kinase



Acne Inversa-like Lesions Induced by a Low Dose of Sorafenib.


Drug Screening of Potential Multiple Target Inhibitors for Estrogen Receptor-α-positive Breast Cancer

Threonine Kinase sentence examples within dependent protein kinase



Hydrogen sulfide of air induces macrophage extracellular traps to aggravate inflammatory injury via the regulation of miR-15b-5p on MAPK and insulin signals in trachea of chickens.


The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF

Threonine Kinase sentence examples within rapamycin complex 1



mTOR signaling mediates ILC3-driven immunopathology.


The Regulation of Polyamine Pathway Proteins in Models of Skeletal Muscle Hypertrophy and Atrophy - a potential role for mTORC1.

Threonine Kinase sentence examples within enrichment analysis revealed



Identification of Seven Cell Cycle-Related Genes with Unfavorable Prognosis and Construction of their TF-miRNA-mRNA regulatory network in Breast Cancer


Identifying the active compounds and mechanism of action of Banxia Xiexin decoction for treating ethanol-induced chronic gastritis using network pharmacology combined with UPLC-LTQ-Orbitrap MS

Threonine Kinase sentence examples within cyclin dependent protein



An Investigation of the Antigastric Cancer Effect in Tumor Microenvironment of Radix Rhei Et Rhizome: A Network Pharmacology Study


ARHGEF10L Promotes Cervical Tumorigenesis via RhoA-Mediated Signaling

Threonine Kinase sentence examples within estrogen receptor 1



Nitric oxide inhibition assay and the respective target identification of an aptamer designed to control atherosclerosis.


Bioinformatics analysis and quantitative weight of evidence assessment to map the potential mode of actions of bisphenol A.

Threonine Kinase sentence examples within phosphatidylinositol 45 bisphosphate



Prognostic value of the PIK3CA, AKT, and PTEN mutations in oral squamous cell carcinoma: literature review


Hsa_circ_0066523 promotes the proliferation and osteogenic differentiation of bone mesenchymal stem cells by repressing PTEN

Threonine Kinase sentence examples within monophosphate activated protein



AMPK and Pulmonary Hypertension: Crossroads Between Vasoconstriction and Vascular Remodeling


Enhanced Hexokinase 2 Expression and Lactate Production Promote The Apoptosis of Dopaminergic Neurons in Parkinson’s Disease

Threonine Kinase sentence examples within calcium calmodulin dependent



Autoregulatory Control of Microtubule Binding in Doublecortin-Like Kinase 1


Small-Molecule Inhibitor Targeting Protein Kinase D: A Potential Therapeutic Strategy

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Roles of NEK family in cell cycle regulation.


TTK inhibitor promotes radiosensitivity of liver cancer cells through p21.

Threonine Kinase sentence examples within programmed cell death



The spliced leader RNA silencing (SLS) pathway in Trypanosoma brucei is induced by perturbations of endoplasmic reticulum, Golgi, or mitochondrial proteins factors and functional analysis of SLS inducing kinase, PK3


QSAR Analysis of Quinazolinyl-arylurea Derivatives as Potential Anti-Cancer Agents: GA-MLR Chemometric Approach

Threonine Kinase sentence examples within insulin receptor substrate



[Effect of fucoxanthin on insulin resistance in obese mice induced by high fat diet].


Neonatal nicotine exposure changes insulin status in fat depots: sex-related differences.

Threonine Kinase sentence examples within growth factor receptor



Role of Glycans on Key Cell Surface Receptors That Regulate Cell Proliferation and Cell Death


An Integrated Approach Based on Network Pharmacology Combined with Experimental Verification Reveals AMPK/PI3K/Akt Signaling is an Important Way for the Anti-Type 2 Diabetic Activity of Silkworm Excrement

Threonine Kinase sentence examples within green fluorescent protein



Autophagy restricts mitochondrial DNA damage-induced release of ENDOG (endonuclease G) to regulate genome stability.


Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.

Threonine Kinase sentence examples within vascular endothelial growth



Human mesenchymal stem cells promote ischemic repairment and angiogenesis of diabetic foot through exosome miRNA-21-5p.


IARS2 regulates proliferation, migration, and angiogenesis of human umbilical vein endothelial cells.

Threonine Kinase sentence examples within regulated kinase 1



Cetyltrimethylammonium Bromide Attenuates the Mesenchymal Characteristics of Hypopharyngeal Squamous Cell Carcinoma Through Inhibiting the EGFR/PI3K/AKT Signaling Pathway


Cutaneous and hepatic vascular lesions due to a recurrent somatic GJA4 mutation reveal a pathway for vascular malformation

Threonine Kinase sentence examples within associated protein 1



Hub Gene Identification and Prognostic Model Establishment for Patients with HBV-related Hepatocellular Carcinoma


STK11/LKB1 and KEAP1 mutations in non-small cell lung cancer: Prognostic rather than predictive?

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Genetic Analysis and Fine Mapping of the Fire Blight Resistance Locus of Malus ×arnoldiana on Linkage Group 12 Reveal First Candidate Genes


LRRK2-NFATc2 Pathway Associated with Neuroinflammation May Be a Potential Therapeutic Target for Parkinson’s Disease

Threonine Kinase sentence examples within p38 mitogen activated



p38-mediated cell growth and survival drive rapid embryonic wound repair.


Selenoproteins Protect Against Avian Liver Necrosis by Metabolizing Peroxides and Regulating Receptor Interacting Serine Threonine Kinase 1/Receptor Interacting Serine Threonine Kinase 3/Mixed Lineage Kinase Domain-Like and Mitogen-Activated Protein Kinase Signaling

Threonine Kinase sentence examples within phosphoinositide 3 kinase



Resveratrol promotes apoptosis and G2/M cell cycle arrest of fibroblast-like synoviocytes in rheumatoid arthritis through regulation of autophagy and the serine-threonine kinase-p53 axis


MicroRNA-802 promotes the progression of osteosarcoma through targeting p27 and activating PI3K/AKT pathway

Threonine Kinase sentence examples within element binding protein



The ménage à trois of autophagy, lipid droplets and liver disease.


Estrogen receptor β alleviates inflammatory lesions in a rat model of inflammatory bowel disease via down-regulating P2X7R expression in macrophages.

Threonine Kinase sentence examples within binding protein 1



m6A reader YTHDC1 modulates autophagy by targeting SQSTM1 in diabetic skin.