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A novel target for combination immunotherapy in pancreatic cancer: IL-1β mediates immunosuppression in the tumour microenvironment.


High Pulsatile Load Decreases Arterial Stiffness: An ex vivo Study

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Nuclear receptor NR5A2 negatively regulates cell proliferation and tumor growth in nervous system malignancies


Cold atmospheric plasma selectively induces G0/G1 cell cycle arrest and apoptosis in AR-independent prostate cancer cells

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Nonbone Marrow CD34+ Cells Are Crucial for Endothelial Repair of Injured Artery


Harnessing the IL-21-BATF Pathway in the CD8+ T Cell Anti-Tumor Response


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Honokiol: A review of its pharmacological potential and therapeutic insights.



Modeling regulatory network topology improves genome-wide analyses of complex human traits



Identification of novel genetic susceptibility loci for thoracic and abdominal aortic aneurysms via genome-wide association study using the UK Biobank Cohort



Analysis of UK Biobank Cohort Reveals Novel Insights for Thoracic and Abdominal Aortic Aneurysms



Migraine: beyond pain



A protein interaction landscape of breast cancer



Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response



POS0376 MONOMERIC C REACTIVE PROTEIN (mCRP) REGULATES INFLAMMATORY RESPONSES IN HUMAN AND MOUSE CHONDROCYTES



The Ultrastructure of Tissue Damage by Amyloid Fibrils



Renal dysfunctions and liver disease: a brief update on management with particular attention to hepatorenal syndrome.



Polyphenolics and therapeutic insights in different tissues extract and fractions of Camellia sinensis (L.) Kuntze (Kangra Tea)



Tailoring photosensitive ROS for advanced photodynamic therapy



Searching for the Culprit: When Diabetic Ketoacidosis Presents With Insulin Autoantibodies



SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors



Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity



Foldamers Reveal and Validate Novel Therapeutic Targets Associated with Toxic α-Synuclein Self-Assembly



Deletion of Coagulation Factor IX Compromises Bone Mass and Strength: Murine Model of Hemophilia B (Christmas Disease)



A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels



Posttranslational Modifications Associated With Cancer and Their Therapeutic Implications



The lysine catabolite saccharopine impairs development by disrupting mitochondrial homeostasis



A Markov decision process for modeling adverse drug reactions in medication treatment of type 2 diabetes



Plasma mitochondrial DNA is associated with extrapulmonary sarcoidosis



PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors



Serum pro‐inflammatory and anti‐inflammatory cytokines and the pathogenesis of experimental autoimmune encephalomyelitis



Context‐dependent regulation of receptor tyrosine kinases: Insights from systems biology approaches



Polyphenolic flavonoid (Myricetin) upregulated proteasomal degradation mechanisms: Eliminates neurodegenerative proteins aggregation



In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy



Detection of Anaplastic Lymphoma Kinase-Rearranged Mesothelioma Cells in Ascites by Companion Diagnostics



Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates.


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Therapeutic Insights 치료 통찰력


Therapeutic Insights 치료 통찰력
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