Targeting Cyclin Dependent 사이클린 종속 타겟팅

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10.1200/JCO.2021.39.15_SUPPL.E12506

Pharmacologically targeting cyclin-dependent kinases 4 and 6 (CDK4 & 6) has proven to be a successful therapeutic approach in patients with estrogen receptor positive (ER+) breast cancer.

사이클린 의존성 키나아제 4 및 6(CDK4 & 6)을 약리학적으로 표적화하는 것은 에스트로겐 수용체 양성(ER+) 유방암 환자에서 성공적인 치료 접근 방식으로 입증되었습니다.

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10.3390/cancers13123039

Targeting cyclin-dependent kinase 9 (CDK9) is an emerging therapeutic approach that has the potential to overcome the challenges in glioblastoma management.

Cyclin-dependent kinase 9(CDK9)를 표적으로 하는 것은 교모세포종 관리의 문제를 극복할 수 있는 잠재력이 있는 새로운 치료 접근법입니다.

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10.1016/j.bbcan.2021.188606

Inhibitors targeting cyclin-dependent kinase 4/6, poly-ADP-ribose polymerase, insulin-like growth factor-1 receptor, mTOR, NTRK, metabolisms, and epigenetic drugs are under clinical evaluation for sarcomas bearing the corresponding signals.

사이클린 의존성 키나제 4/6, 폴리-ADP-리보스 폴리머라제, 인슐린 유사 성장 인자-1 수용체, mTOR, NTRK, 대사 및 후성 유전 약물을 표적으로 하는 억제제는 해당 신호를 갖는 육종에 대해 임상 평가 중입니다.

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10.21203/RS.3.RS-415596/V1

Conclusion: Flavopiridol mitigates the progression of monocrotaline-induced pulmonary hypertension in rats by targeting cyclin-dependent kinase 9.

결론: 플라보피리돌은 사이클린 의존성 키나제 9를 표적으로 하여 쥐에서 모노크로탈린 유발 폐 고혈압의 진행을 완화합니다.

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Keywords related to Targeting

Targeting Strategies Targeting Mir 21 Targeting Cholesterol Targeting Activated Targeting Stat1 Targeting Parents Targeting Cd44 Targeting Mir 145 Targeting Programmed Targeting People Targeting Signaling Targeting Tumour Targeting Il 23 Targeting Microglial Targeting Nonstructural Targeting Lasp1 Targeting Breast Targeting P21 Targeting Matrix Targeting Autophagy Targeting Survivin Targeting Theranostic Targeting Fpga Targeting Anaemia Targeting Yap Targeting Immune Targeting P53 Targeting Bruton Targeting Ras Targeting Ige Targeting Total Targeting Proprotein Targeting Htert Targeting Cbx3 Hp1g Targeting Strategy Targeting Zeb1 Targeting Zeb2 Targeting Mitochondria Targeting Lyn Targeting Tnf Targeting Ability Targeting Mitochondrial Targeting Adam9 Targeting Tlr4 Nfkb Targeting Putative Targeting Dna Targeting Cancer Targeting Lung Targeting Interleukin Targeting Estrogen Explore More

Keywords related to Dependent

Illumination Dependent Oxide Synthase Dependent Er Stress Dependent Non Insulin Dependent Nonlinear Saturation Dependent Sars Cov 2 Rna Dependent Non Transfusion Dependent Androgen Receptor Dependent Linear Response Time Dependent Censored Dependent Morphine Dependent Selective Cyclin Dependent Functionally Dependent Transfusion Dependent Cortical Depth Dependent Stock Dependent Ph Dependent Time Dependent Protein Dependent Fitness Dependent Induces Ros Dependent Sequence Dependent Hormone Dependent Mode Dependent Real Time Time Dependent Anion Dependent Receptor 4 Dependent Process Dependent Stochastic Time Dependent Detoxified Alcohol Dependent Environment Dependent Cells Dependent Source Dependent Oxide Dependent Context Dependent Oxidative Stress Dependent Nonlinear State Dependent Cannabis Dependent Bias Dependent Parenteral Nutrition Dependent Amino Acid Dependent Function Dependent Environmental Context Dependent Parameters Dependent Model Dependent Ligand Dependent Mitochondrial Atp Dependent Abscisic Acid Dependent Cyclic Gmp Dependent Exposure Dependent Explore More

Targeting Cyclin Dependent 사이클린 종속 타겟팅

Targeting Cyclin Dependent 사이클린 종속 타겟팅

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Sep 23, 2023

Targeting Cyclin Dependent(사이클린 종속 타겟팅)란 무엇입니까?

Targeting Cyclin Dependent 사이클린 종속 타겟팅 - Pharmacologically targeting cyclin-dependent kinases 4 and 6 (CDK4 & 6) has proven to be a successful therapeutic approach in patients with estrogen receptor positive (ER+) breast cancer. ^[1] Targeting cyclin-dependent kinase 9 (CDK9) is an emerging therapeutic approach that has the potential to overcome the challenges in glioblastoma management. ^[2] Inhibitors targeting cyclin-dependent kinase 4/6, poly-ADP-ribose polymerase, insulin-like growth factor-1 receptor, mTOR, NTRK, metabolisms, and epigenetic drugs are under clinical evaluation for sarcomas bearing the corresponding signals. ^[3] Conclusion: Flavopiridol mitigates the progression of monocrotaline-induced pulmonary hypertension in rats by targeting cyclin-dependent kinase 9. ^[4]
사이클린 의존성 키나아제 4 및 6(CDK4 & 6)을 약리학적으로 표적화하는 것은 에스트로겐 수용체 양성(ER+) 유방암 환자에서 성공적인 치료 접근 방식으로 입증되었습니다. ^[1] Cyclin-dependent kinase 9(CDK9)를 표적으로 하는 것은 교모세포종 관리의 문제를 극복할 수 있는 잠재력이 있는 새로운 치료 접근법입니다. ^[2] 사이클린 의존성 키나제 4/6, 폴리-ADP-리보스 폴리머라제, 인슐린 유사 성장 인자-1 수용체, mTOR, NTRK, 대사 및 후성 유전 약물을 표적으로 하는 억제제는 해당 신호를 갖는 육종에 대해 임상 평가 중입니다. ^[3] 결론: 플라보피리돌은 사이클린 의존성 키나제 9를 표적으로 하여 쥐에서 모노크로탈린 유발 폐 고혈압의 진행을 완화합니다. ^[4]