Synthesized Compounds
합성 화합물
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Synthesized Compounds sentence examples within molecular docking study
Molecular docking studies were performed on the synthesized compounds using Staphylococcus aureus dihydropteroate synthase (saDHPS) (6CLV) and DNA gyrase (1KZN) proteins.
분자 도킹 연구는 황색 포도구균 디히드로프테로에이트 합성효소(saDHPS)(6CLV) 및 DNA 자이라제(1KZN) 단백질을 사용하여 합성된 화합물에 대해 수행되었습니다.
Molecular docking studies were performed on the synthesized compounds using Staphylococcus aureus dihydropteroate synthase (saDHPS) (6CLV) and DNA gyrase (1KZN) proteins.
분자 도킹 연구는 황색 포도구균 디히드로프테로에이트 합성효소(saDHPS)(6CLV) 및 DNA 자이라제(1KZN) 단백질을 사용하여 합성된 화합물에 대해 수행되었습니다.
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Besides, the potential mode of action of the synthesized compounds was determined by employing a molecular-docking study against penicillinbinding protein implicated in anti-bacterial action.
게다가, 합성된 화합물의 잠재적인 작용 방식은 항균 작용과 관련된 페니실린 결합 단백질에 대한 분자 도킹 연구를 사용하여 결정되었습니다.
Besides, the potential mode of action of the synthesized compounds was determined by employing a molecular-docking study against penicillinbinding protein implicated in anti-bacterial action.
게다가, 합성된 화합물의 잠재적인 작용 방식은 항균 작용과 관련된 페니실린 결합 단백질에 대한 분자 도킹 연구를 사용하여 결정되었습니다.
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Synthesized Compounds sentence examples within cancer cell line
The synthesized compounds possess antiproliferative activities against different cancer cell lines and significantly less cytotoxic to normal cells.
합성된 화합물은 다른 암 세포주에 대해 항증식 활성을 가지며 정상 세포에 대해 현저히 적은 세포독성을 갖는다.
The synthesized compounds possess antiproliferative activities against different cancer cell lines and significantly less cytotoxic to normal cells.
합성된 화합물은 다른 암 세포주에 대해 항증식 활성을 가지며 정상 세포에 대해 현저히 적은 세포독성을 갖는다.
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The anticancer effects of the synthesized compounds were assayed using MTT assay against cancer cell lines K562 and MG63.
합성된 화합물의 항암 효과는 암세포주 K562 및 MG63에 대한 MTT 분석을 사용하여 분석되었습니다.
The anticancer effects of the synthesized compounds were assayed using MTT assay against cancer cell lines K562 and MG63.
합성된 화합물의 항암 효과는 암세포주 K562 및 MG63에 대한 MTT 분석을 사용하여 분석되었습니다.
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Synthesized Compounds sentence examples within structure activity relationship
The preliminary structure-activity relationships (SARs) of the synthesized compounds were also investigated.
합성된 화합물의 예비 구조-활성 관계(SAR)도 조사되었습니다.
The preliminary structure-activity relationships (SARs) of the synthesized compounds were also investigated.
합성된 화합물의 예비 구조-활성 관계(SAR)도 조사되었습니다.
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Based on previously identified antiplasmodial hit-molecules belonging to the 2-trichloromethylquinazoline and 3-trichloromethylquinoxaline series, we report herein an antiplasmodial Structure-Activity Relationships (SAR) study at position two of the quinoxaline ring of 16 newly synthesized compounds.
2-트리클로로메틸퀴나졸린 및 3-트리클로로메틸퀴녹살린 계열에 속하는 이전에 확인된 항포체 히트 분자를 기반으로, 우리는 여기에서 새로 합성된 16개 화합물의 퀴녹살린 고리의 위치 2에서 항포체 구조-활성 관계(SAR) 연구를 보고합니다.
Based on previously identified antiplasmodial hit-molecules belonging to the 2-trichloromethylquinazoline and 3-trichloromethylquinoxaline series, we report herein an antiplasmodial Structure-Activity Relationships (SAR) study at position two of the quinoxaline ring of 16 newly synthesized compounds.
2-트리클로로메틸퀴나졸린 및 3-트리클로로메틸퀴녹살린 계열에 속하는 이전에 확인된 항포체 히트 분자를 기반으로, 우리는 여기에서 새로 합성된 16개 화합물의 퀴녹살린 고리의 위치 2에서 항포체 구조-활성 관계(SAR) 연구를 보고합니다.
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Synthesized Compounds sentence examples within human cancer cell
The synthesized compounds were evaluated for cytotoxic activity against diverse human cancer cell lines by the National Cancer Institute.
합성된 화합물은 국립 암 연구소에 의해 다양한 인간 암 세포주에 대한 세포 독성 활성에 대해 평가되었습니다.
The synthesized compounds were evaluated for cytotoxic activity against diverse human cancer cell lines by the National Cancer Institute.
합성된 화합물은 국립 암 연구소에 의해 다양한 인간 암 세포주에 대한 세포 독성 활성에 대해 평가되었습니다.
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Five of the synthesized compounds displayed good cytotoxic activity against two human cancer cell lines, KB and HepG2, with half maximal inhibitory concentration values in a range of 4–20 μM.
합성된 화합물 중 5개는 2개의 인간 암 세포주인 KB 및 HepG2에 대해 우수한 세포독성 활성을 나타내었으며 4-20μM 범위의 최대 억제 농도 값의 절반을 나타냅니다.
Five of the synthesized compounds displayed good cytotoxic activity against two human cancer cell lines, KB and HepG2, with half maximal inhibitory concentration values in a range of 4–20 μM.
합성된 화합물 중 5개는 2개의 인간 암 세포주인 KB 및 HepG2에 대해 우수한 세포독성 활성을 나타내었으며 4-20μM 범위의 최대 억제 농도 값의 절반을 나타냅니다.
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Synthesized Compounds sentence examples within anti proliferative activity
The anti-proliferative activity of the newly synthesized compounds among the synthesized compounds toward the six cancer cell lines namely A549, H460, HT-29, MKN-45, U87MG, and SMMC-7721 was studied.
합성된 화합물 중 새로 합성된 화합물의 A549, H460, HT-29, MKN-45, U87MG, SMMC-7721 등 6개 암세포주에 대한 항증식 활성을 조사하였다.
The anti-proliferative activity of the newly synthesized compounds among the synthesized compounds toward the six cancer cell lines namely A549, H460, HT-29, MKN-45, U87MG, and SMMC-7721 was studied.
합성된 화합물 중 새로 합성된 화합물의 A549, H460, HT-29, MKN-45, U87MG, SMMC-7721 등 6개 암세포주에 대한 항증식 활성을 조사하였다.
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Adriamycin and etoposide were used as reference compounds for the evaluation of topo IIα inhibitory and anti-proliferative activity of the synthesized compounds.
Adriamycin과 etoposide는 합성된 화합물의 topo IIα 억제 및 항증식 활성 평가를 위한 참조 화합물로 사용되었습니다.
Adriamycin and etoposide were used as reference compounds for the evaluation of topo IIα inhibitory and anti-proliferative activity of the synthesized compounds.
Adriamycin과 etoposide는 합성된 화합물의 topo IIα 억제 및 항증식 활성 평가를 위한 참조 화합물로 사용되었습니다.
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Synthesized Compounds sentence examples within anti inflammatory activity
After confirmation of the structure of the synthesized compounds using spectroscopic methods (FT-IR, and NMR spectral data), their anti-inflammatory activity was evaluated using carrageenan-induced paw edema model in male Wistar rats (200–220 g) administered intraperitoneally at doses of 100 and 200 mg/kg.
분광법(FT-IR 및 NMR 스펙트럼 데이터)을 사용하여 합성된 화합물의 구조를 확인한 후, 복강내 투여된 수컷 Wistar 쥐(200-220g)에서 carrageenan 유발 발 부종 모델을 사용하여 항염증 활성을 평가했습니다. 100 및 200mg/kg의 용량.
After confirmation of the structure of the synthesized compounds using spectroscopic methods (FT-IR, and NMR spectral data), their anti-inflammatory activity was evaluated using carrageenan-induced paw edema model in male Wistar rats (200–220 g) administered intraperitoneally at doses of 100 and 200 mg/kg.
분광법(FT-IR 및 NMR 스펙트럼 데이터)을 사용하여 합성된 화합물의 구조를 확인한 후, 복강내 투여된 수컷 Wistar 쥐(200-220g)에서 carrageenan 유발 발 부종 모델을 사용하여 항염증 활성을 평가했습니다. 100 및 200mg/kg의 용량.
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The newly synthesized compounds (SP1-SP13) were evaluated biologically for their antioxidant, α-amylase enzyme inhibition, antimicrobial, cytotoxic, and anti-inflammatory activities.
새로 합성된 화합물(SP1-SP13)은 항산화, α-아밀라아제 효소 억제, 항균, 세포 독성 및 항염 활성에 대해 생물학적으로 평가되었습니다.
The newly synthesized compounds (SP1-SP13) were evaluated biologically for their antioxidant, α-amylase enzyme inhibition, antimicrobial, cytotoxic, and anti-inflammatory activities.
새로 합성된 화합물(SP1-SP13)은 항산화, α-아밀라아제 효소 억제, 항균, 세포 독성 및 항염 활성에 대해 생물학적으로 평가되었습니다.
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Synthesized Compounds sentence examples within vitro antimicrobial activity
The synthesized compounds were tested for their in vitro antimicrobial activity using the broth dilution method against Staphylococcus aureus (gram-positive) and E.
합성된 화합물은 Staphylococcus aureus(그람 양성) 및 E.
The synthesized compounds were tested for their in vitro antimicrobial activity using the broth dilution method against Staphylococcus aureus (gram-positive) and E.
합성된 화합물은 Staphylococcus aureus(그람 양성) 및 E.
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Also, several synthesized compounds were screened for their in vitro antimicrobial activities by employing the disk diffusion test on Gram-negative as well as Gram-positive bacteria.
또한, 그람-음성 및 그람-양성 세균에 대한 디스크 확산 시험을 사용하여 몇몇 합성된 화합물의 시험관내 항균 활성에 대해 스크리닝하였다.
Also, several synthesized compounds were screened for their in vitro antimicrobial activities by employing the disk diffusion test on Gram-negative as well as Gram-positive bacteria.
또한, 그람-음성 및 그람-양성 세균에 대한 디스크 확산 시험을 사용하여 몇몇 합성된 화합물의 시험관내 항균 활성에 대해 스크리닝하였다.
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Synthesized Compounds sentence examples within nuclear magnetic resonance
Structural validation and characterization of all the newly synthesized compounds were evaluated by spectral analysis (mass spectrometry, proton nuclear magnetic resonance (1HNMR), and Carbon-13 nuclear magnetic resonance(13CNMR)spectroscopies.
새로 합성된 모든 화합물의 구조적 검증 및 특성화는 스펙트럼 분석(질량 분석, 양성자 핵 자기 공명(1HNMR) 및 탄소-13 핵 자기 공명(13CNMR) 분광법)에 의해 평가되었습니다.
Structural validation and characterization of all the newly synthesized compounds were evaluated by spectral analysis (mass spectrometry, proton nuclear magnetic resonance (1HNMR), and Carbon-13 nuclear magnetic resonance(13CNMR)spectroscopies.
새로 합성된 모든 화합물의 구조적 검증 및 특성화는 스펙트럼 분석(질량 분석, 양성자 핵 자기 공명(1HNMR) 및 탄소-13 핵 자기 공명(13CNMR) 분광법)에 의해 평가되었습니다.
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All the newly synthesized compounds were characterized by Fourier-transform infrared spectrophotometry, proton and carbon nuclear magnetic resonance, and electrospray ionization-mass spectrometry.
새로 합성된 모든 화합물은 푸리에 변환 적외선 분광광도법, 양성자 및 탄소 핵 자기 공명, 전자분무 이온화 질량 분석법으로 특성화되었습니다.
All the newly synthesized compounds were characterized by Fourier-transform infrared spectrophotometry, proton and carbon nuclear magnetic resonance, and electrospray ionization-mass spectrometry.
새로 합성된 모든 화합물은 푸리에 변환 적외선 분광광도법, 양성자 및 탄소 핵 자기 공명, 전자분무 이온화 질량 분석법으로 특성화되었습니다.
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Synthesized Compounds sentence examples within breast cancer cell
The synthesized compounds against breast cancer cell lines; MCF-7 and MDA-MB-231
and epidermoid carcinoma; A431 showed that the complex contributed to reduce the percentage of
cell viability toward all the tested cell lines but remarkable contribution toward MDA-MB-231 cell
line.
유방암 세포주에 대한 합성 화합물; MCF-7 및 MDA-MB-231
및 표피양 암종; A431은 복합물이
시험된 모든 세포주에 대한 세포 생존력, 그러나 MDA-MB-231 세포에 대한 현저한 기여
선.
The synthesized compounds against breast cancer cell lines; MCF-7 and MDA-MB-231
and epidermoid carcinoma; A431 showed that the complex contributed to reduce the percentage of
cell viability toward all the tested cell lines but remarkable contribution toward MDA-MB-231 cell
line.
유방암 세포주에 대한 합성 화합물; MCF-7 및 MDA-MB-231 및 표피양 암종; A431은 복합물이 시험된 모든 세포주에 대한 세포 생존력, 그러나 MDA-MB-231 세포에 대한 현저한 기여 선.
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The breast cancer cell line MDA-MB-231 was treated with these synthesized compounds and IC50 was evaluated by MTT assay method.
유방암 세포주 MDA-MB-231을 합성된 화합물로 처리하고 IC50을 MTT 분석법으로 평가하였다.
The breast cancer cell line MDA-MB-231 was treated with these synthesized compounds and IC50 was evaluated by MTT assay method.
유방암 세포주 MDA-MB-231을 합성된 화합물로 처리하고 IC50을 MTT 분석법으로 평가하였다.
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Synthesized Compounds sentence examples within vitro antibacterial activity
All the synthesized compounds 2(a-k) were assayed for in vitro antibacterial activity against a selected bacterial strain and the compound (2 h) and (2k) exerted excellent activity against Staphylococcus aureus, Escherichia coli and Salmonella typhi strains.
합성된 모든 화합물 2(a-k)는 선택된 박테리아 균주에 대한 시험관내 항균 활성에 대해 분석되었고 화합물 (2h) 및 (2k)는 황색포도상구균, 대장균 및 Salmonella typhi 균주에 대해 우수한 활성을 나타냈다.
All the synthesized compounds 2(a-k) were assayed for in vitro antibacterial activity against a selected bacterial strain and the compound (2 h) and (2k) exerted excellent activity against Staphylococcus aureus, Escherichia coli and Salmonella typhi strains.
합성된 모든 화합물 2(a-k)는 선택된 박테리아 균주에 대한 시험관내 항균 활성에 대해 분석되었고 화합물 (2h) 및 (2k)는 황색포도상구균, 대장균 및 Salmonella typhi 균주에 대해 우수한 활성을 나타냈다.
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We then investigated the in vitro antibacterial activities of synthesized compounds against ten bacterial strains of clinical interest in comparison to aztreonam and ceftazidime.
그런 다음 우리는 aztreonam 및 ceftazidime과 비교하여 임상적으로 관심 있는 10가지 박테리아 균주에 대해 합성된 화합물의 시험관 내 항균 활성을 조사했습니다.
We then investigated the in vitro antibacterial activities of synthesized compounds against ten bacterial strains of clinical interest in comparison to aztreonam and ceftazidime.
그런 다음 우리는 aztreonam 및 ceftazidime과 비교하여 임상적으로 관심 있는 10가지 박테리아 균주에 대해 합성된 화합물의 시험관 내 항균 활성을 조사했습니다.
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Synthesized Compounds sentence examples within four cancer cell
The synthesized compounds were evaluated for anticancer activity against four cancer cell lines: MCF-7 (breast cancer), A549 (lung cancer), Colo-205 (colon cancer), and A2780 (ovarian cancer).
합성된 화합물은 MCF-7(유방암), A549(폐암), Colo-205(대장암), A2780(난소암) 등 4개 암세포주에 대한 항암 활성을 평가했다.
The synthesized compounds were evaluated for anticancer activity against four cancer cell lines: MCF-7 (breast cancer), A549 (lung cancer), Colo-205 (colon cancer), and A2780 (ovarian cancer).
합성된 화합물은 MCF-7(유방암), A549(폐암), Colo-205(대장암), A2780(난소암) 등 4개 암세포주에 대한 항암 활성을 평가했다.
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The synthesized compounds were screened for their antiproliferative activity against four cancer cell lines (Pc-3 A549, Hela, HepG2) using the SRB method.
합성된 화합물은 SRB 방법을 사용하여 4개의 암 세포주(Pc-3 A549, Hela, HepG2)에 대한 항증식 활성에 대해 스크리닝되었습니다.
The synthesized compounds were screened for their antiproliferative activity against four cancer cell lines (Pc-3 A549, Hela, HepG2) using the SRB method.
합성된 화합물은 SRB 방법을 사용하여 4개의 암 세포주(Pc-3 A549, Hela, HepG2)에 대한 항증식 활성에 대해 스크리닝되었습니다.
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Synthesized Compounds sentence examples within transform infrared spectroscopy
To characterize the synthesized compounds with the help of X-ray diffraction (XRD), Thermogravimetric & Differential Thermogravimetric Analysis (TG-TDA), Fourier Transform Infrared spectroscopy (FT-IR), Ultra-Violet spectroscopy (UV-Vis), Scanning Electron Microscope with Energy Dispersive X-ray Analysis (SEM with EDAX), and Vibrating Sample Magnetometer techniques (VSM).
X선 회절(XRD), 열중량 및 시차 열중량 분석(TG-TDA), 푸리에 변환 적외선 분광법(FT-IR), 자외선 분광법(UV-Vis), 주사 전자의 도움으로 합성된 화합물의 특성화 에너지 분산 X선 분석(EDAX를 사용한 SEM) 및 진동 샘플 자력계 기술(VSM)이 있는 현미경.
To characterize the synthesized compounds with the help of X-ray diffraction (XRD), Thermogravimetric & Differential Thermogravimetric Analysis (TG-TDA), Fourier Transform Infrared spectroscopy (FT-IR), Ultra-Violet spectroscopy (UV-Vis), Scanning Electron Microscope with Energy Dispersive X-ray Analysis (SEM with EDAX), and Vibrating Sample Magnetometer techniques (VSM).
X선 회절(XRD), 열중량 및 시차 열중량 분석(TG-TDA), 푸리에 변환 적외선 분광법(FT-IR), 자외선 분광법(UV-Vis), 주사 전자의 도움으로 합성된 화합물의 특성화 에너지 분산 X선 분석(EDAX를 사용한 SEM) 및 진동 샘플 자력계 기술(VSM)이 있는 현미경.
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Synthesized compounds were characterized by the techniques of Fourier-Transform Infrared Spectroscopy, Nuclear Magnetic Resonance, Thermogravimetric Analysis and Transmission Electron Microscopy.
합성된 화합물은 푸리에 변환 적외선 분광법, 핵 자기 공명법, 열중량 분석 및 투과 전자 현미경 기술로 특성화되었습니다.
Synthesized compounds were characterized by the techniques of Fourier-Transform Infrared Spectroscopy, Nuclear Magnetic Resonance, Thermogravimetric Analysis and Transmission Electron Microscopy.
합성된 화합물은 푸리에 변환 적외선 분광법, 핵 자기 공명법, 열중량 분석 및 투과 전자 현미경 기술로 특성화되었습니다.
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Synthesized Compounds sentence examples within human breast cancer
Also, the synthesized compounds were screened for studying their cytotoxic activity against the human breast cancer cell line (MCF-7).
또한, 합성된 화합물을 인간 유방암 세포주(MCF-7)에 대한 세포독성 활성을 연구하기 위해 스크리닝하였다.
Also, the synthesized compounds were screened for studying their cytotoxic activity against the human breast cancer cell line (MCF-7).
또한, 합성된 화합물을 인간 유방암 세포주(MCF-7)에 대한 세포독성 활성을 연구하기 위해 스크리닝하였다.
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All synthesized compounds were screened for anticancer activity against two different human breast cancer cell lines (MDA-MB-231 and MCF-7).
합성된 모든 화합물은 두 가지 다른 인간 유방암 세포주(MDA-MB-231 및 MCF-7)에 대한 항암 활성에 대해 스크리닝되었습니다.
All synthesized compounds were screened for anticancer activity against two different human breast cancer cell lines (MDA-MB-231 and MCF-7).
합성된 모든 화합물은 두 가지 다른 인간 유방암 세포주(MDA-MB-231 및 MCF-7)에 대한 항암 활성에 대해 스크리닝되었습니다.
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Synthesized Compounds sentence examples within absorption distribution metabolism
The ADME (absorption, distribution, metabolism, and excretion) drug‐like properties of the synthesized compounds were predicted through the SwissADME software.
SwissADME 소프트웨어를 통해 합성된 화합물의 ADME(흡수, 분포, 대사 및 배설) 약물 유사 특성을 예측했습니다.
The ADME (absorption, distribution, metabolism, and excretion) drug‐like properties of the synthesized compounds were predicted through the SwissADME software.
SwissADME 소프트웨어를 통해 합성된 화합물의 ADME(흡수, 분포, 대사 및 배설) 약물 유사 특성을 예측했습니다.
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To explore the medicinal probability of OBG-based esters, all the synthesized compounds were subjected to in silico PASS (prediction of activity spectra for substances) predication and ADMET (absorption, distribution, metabolism, excretion, and toxicity) studies.
OBG 기반 에스테르의 의약적 가능성을 조사하기 위해 합성된 모든 화합물에 대해 in silico PASS(물질에 대한 활성 스펙트럼 예측) 예측 및 ADMET(흡수, 분포, 대사, 배설 및 독성) 연구를 수행했습니다.
To explore the medicinal probability of OBG-based esters, all the synthesized compounds were subjected to in silico PASS (prediction of activity spectra for substances) predication and ADMET (absorption, distribution, metabolism, excretion, and toxicity) studies.
OBG 기반 에스테르의 의약적 가능성을 조사하기 위해 합성된 모든 화합물에 대해 in silico PASS(물질에 대한 활성 스펙트럼 예측) 예측 및 ADMET(흡수, 분포, 대사, 배설 및 독성) 연구를 수행했습니다.
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Synthesized Compounds sentence examples within three human cancer
The synthesized compounds were tested against three human cancer cell lines (HepG-2, MCF-7 and HCT-116) aiming to evaluate its anti-proliferative activities.
합성된 화합물은 항증식 활성을 평가하기 위해 3가지 인간 암 세포주(HepG-2, MCF-7 및 HCT-116)에 대해 테스트되었습니다.
The synthesized compounds were tested against three human cancer cell lines (HepG-2, MCF-7 and HCT-116) aiming to evaluate its anti-proliferative activities.
합성된 화합물은 항증식 활성을 평가하기 위해 3가지 인간 암 세포주(HepG-2, MCF-7 및 HCT-116)에 대해 테스트되었습니다.
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The inhibitory potential of the synthesized compounds on the viability of three human cancer cell lines HEP3BPN 11 (liver), MDA-MB 453 (breast), and HL 60 (leukemia) were assessed.
3가지 인간 암 세포주 HEP3BPN 11(간), MDA-MB 453(유방) 및 HL 60(백혈병)의 생존 가능성에 대한 합성된 화합물의 억제 가능성을 평가했습니다.
The inhibitory potential of the synthesized compounds on the viability of three human cancer cell lines HEP3BPN 11 (liver), MDA-MB 453 (breast), and HL 60 (leukemia) were assessed.
3가지 인간 암 세포주 HEP3BPN 11(간), MDA-MB 453(유방) 및 HL 60(백혈병)의 생존 가능성에 대한 합성된 화합물의 억제 가능성을 평가했습니다.
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Synthesized Compounds sentence examples within radical scavenging activity
The synthesized compounds (4a-o) were characterized by 1 HNMR, 13 CNMR and HRMS spectra and further screened for radical scavenging activity.
합성된 화합물(4a-o)은 1 HNMR, 13 CNMR 및 HRMS 스펙트럼으로 특성화되었으며 라디칼 소거 활성에 대해 추가로 스크리닝되었습니다.
The synthesized compounds (4a-o) were characterized by 1 HNMR, 13 CNMR and HRMS spectra and further screened for radical scavenging activity.
합성된 화합물(4a-o)은 1 HNMR, 13 CNMR 및 HRMS 스펙트럼으로 특성화되었으며 라디칼 소거 활성에 대해 추가로 스크리닝되었습니다.
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The set of methods, including the study of antioxidant activity (AOA) by the ability to inhibit the initiated oxidation of animal lipids, radical scavenging activity, Fe2+‐chelation ability, as well as a comparative assessment of membrane‐protective activity under the conditions of H2O2‐induced hemolysis of mice red blood cells (RBCs), was used to analyze the antioxidant potential of the synthesized compounds.
동물 지질의 개시 산화를 억제하는 능력, 라디칼 소거 활성, Fe2+-킬레이트화 능력에 의한 항산화 활성(AOA) 연구 및 다음 조건에서 막 보호 활성의 비교 평가를 포함한 일련의 방법 생쥐 적혈구(RBC)의 H2O2 유도 용혈은 합성된 화합물의 항산화 잠재력을 분석하는 데 사용되었습니다.
The set of methods, including the study of antioxidant activity (AOA) by the ability to inhibit the initiated oxidation of animal lipids, radical scavenging activity, Fe2+‐chelation ability, as well as a comparative assessment of membrane‐protective activity under the conditions of H2O2‐induced hemolysis of mice red blood cells (RBCs), was used to analyze the antioxidant potential of the synthesized compounds.
동물 지질의 개시 산화를 억제하는 능력, 라디칼 소거 활성, Fe2+-킬레이트화 능력에 의한 항산화 활성(AOA) 연구 및 다음 조건에서 막 보호 활성의 비교 평가를 포함한 일련의 방법 생쥐 적혈구(RBC)의 H2O2 유도 용혈은 합성된 화합물의 항산화 잠재력을 분석하는 데 사용되었습니다.
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Synthesized Compounds sentence examples within elemental analysis high
The structure of newly synthesized compounds was established by means of elemental analysis, high resolution mass-spectrometry, 1H, 13C-NMR, IR and UV spectroscopy and mass-spectrometry.
새로 합성된 화합물의 구조는 원소 분석, 고해상도 질량 분석법, 1H, 13C-NMR, IR 및 UV 분광법, 질량 분석법을 통해 확립되었습니다.
The structure of newly synthesized compounds was established by means of elemental analysis, high resolution mass-spectrometry, 1H, 13C-NMR, IR and UV spectroscopy and mass-spectrometry.
새로 합성된 화합물의 구조는 원소 분석, 고해상도 질량 분석법, 1H, 13C-NMR, IR 및 UV 분광법, 질량 분석법을 통해 확립되었습니다.
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The structure of the synthesized compounds was established by elemental analysis, high-resolution mass-spectrometry, 1H, 13C-NMR and IR spectroscopy and mass-spectrometry.
합성된 화합물의 구조는 원소 분석, 고해상도 질량 분석법, 1H, 13C-NMR 및 IR 분광법 및 질량 분석법에 의해 확립되었습니다.
The structure of the synthesized compounds was established by elemental analysis, high-resolution mass-spectrometry, 1H, 13C-NMR and IR spectroscopy and mass-spectrometry.
합성된 화합물의 구조는 원소 분석, 고해상도 질량 분석법, 1H, 13C-NMR 및 IR 분광법 및 질량 분석법에 의해 확립되었습니다.
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Synthesized Compounds sentence examples within 22 diphenyl 1
The radical quenching antioxidant activity has been studied on the synthesized compounds by 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay.
라디칼 소광 항산화 활성은 2,2-diphenyl-1-picrylhydrazyl(DPPH) 분석에 의해 합성된 화합물에 대해 연구되었습니다.
The radical quenching antioxidant activity has been studied on the synthesized compounds by 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay.
라디칼 소광 항산화 활성은 2,2-diphenyl-1-picrylhydrazyl(DPPH) 분석에 의해 합성된 화합물에 대해 연구되었습니다.
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The scavenging ability of 2,2-diphenyl-1-picrylhydrazyl and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid radicals by the synthesized compounds was studied for their antioxidant potential and screening for antimicrobial activity by p-iodonitrotetrazolium chloride colorimetric assay.
합성된 화합물에 의한 2,2-diphenyl-1-picrylhydrazyl 및 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid 라디칼) 소거능은 항산화 잠재력과 p-에 의한 항균 활성 스크리닝에 대해 연구되었습니다. 요오도니트로테트라졸륨 클로라이드 비색 분석.
The scavenging ability of 2,2-diphenyl-1-picrylhydrazyl and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid radicals by the synthesized compounds was studied for their antioxidant potential and screening for antimicrobial activity by p-iodonitrotetrazolium chloride colorimetric assay.
합성된 화합물에 의한 2,2-diphenyl-1-picrylhydrazyl 및 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid 라디칼) 소거능은 항산화 잠재력과 p-에 의한 항균 활성 스크리닝에 대해 연구되었습니다. 요오도니트로테트라졸륨 클로라이드 비색 분석.
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Synthesized Compounds sentence examples within scanning electron microscopy
The as-synthesized compounds were characterized by X-ray diffraction (XRD), Fourier-transform infrared (FTIR) spectroscopy, Raman spectroscopy, Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Energy-dispersive X-ray spectroscopy (EDS), and X-ray photoelectron spectroscopy (XPS).
합성된 화합물은 X선 회절(XRD), 푸리에 변환 적외선(FTIR) 분광법, 라만 분광법, 주사 전자 현미경(SEM), 투과 전자 현미경(TEM), 에너지 분산 X선 분광법( EDS) 및 X선 광전자 분광법(XPS).
The as-synthesized compounds were characterized by X-ray diffraction (XRD), Fourier-transform infrared (FTIR) spectroscopy, Raman spectroscopy, Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Energy-dispersive X-ray spectroscopy (EDS), and X-ray photoelectron spectroscopy (XPS).
합성된 화합물은 X선 회절(XRD), 푸리에 변환 적외선(FTIR) 분광법, 라만 분광법, 주사 전자 현미경(SEM), 투과 전자 현미경(TEM), 에너지 분산 X선 분광법( EDS) 및 X선 광전자 분광법(XPS).
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The structural, morphological and optical properties of synthesized compounds were investigated by X-ray diffraction (XRD), Fourier transform infrared (FTIR), UV–Visible diffuse reflectance spectrophotometer (DRS), Field emission scanning electron microscopy (FESEM), and Transmission electron microscopy (TEM).
합성된 화합물의 구조적, 형태적 및 광학적 특성은 X선 회절(XRD), 푸리에 변환 적외선(FTIR), UV-가시광선 확산 반사 분광광도계(DRS), 전계 방출 주사 전자 현미경(FESEM) 및 투과 전자에 의해 조사되었습니다. 현미경(TEM).
The structural, morphological and optical properties of synthesized compounds were investigated by X-ray diffraction (XRD), Fourier transform infrared (FTIR), UV–Visible diffuse reflectance spectrophotometer (DRS), Field emission scanning electron microscopy (FESEM), and Transmission electron microscopy (TEM).
합성된 화합물의 구조적, 형태적 및 광학적 특성은 X선 회절(XRD), 푸리에 변환 적외선(FTIR), UV-가시광선 확산 반사 분광광도계(DRS), 전계 방출 주사 전자 현미경(FESEM) 및 투과 전자에 의해 조사되었습니다. 현미경(TEM).
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Synthesized Compounds sentence examples within addition molecular docking
In addition, molecular docking studies provided support to the in vitro studies and revealed that the synthesized compounds have exhibited significant binding modes with high dock scores ranging from − 6.
또한, 분자 도킹 연구는 시험관 내 연구에 대한 지원을 제공했으며 합성된 화합물이 -6 범위의 높은 도킹 점수로 상당한 결합 모드를 나타냄을 밝혔습니다.
In addition, molecular docking studies provided support to the in vitro studies and revealed that the synthesized compounds have exhibited significant binding modes with high dock scores ranging from − 6.
또한, 분자 도킹 연구는 시험관 내 연구에 대한 지원을 제공했으며 합성된 화합물이 -6 범위의 높은 도킹 점수로 상당한 결합 모드를 나타냄을 밝혔습니다.
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In addition, molecular docking studies shed light on the binding modes of the synthesized compounds.
또한, 분자 도킹 연구는 합성된 화합물의 결합 모드에 대한 정보를 제공합니다.
In addition, molecular docking studies shed light on the binding modes of the synthesized compounds.
또한, 분자 도킹 연구는 합성된 화합물의 결합 모드에 대한 정보를 제공합니다.
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Synthesized Compounds sentence examples within anti cancer activity
RESULTS
All the synthesized compounds were screened for anti-cancer activity against six cancer cell lines, including A 549 (lung), DU 145 (prostate), HT 29 (colon), MCF-7 (breast), SiHA (cervical), B16F10 (mouse skin melanoma) and one normal human fibroblast cell lines.
결과
합성된 모든 화합물은 A 549(폐), DU 145(전립선), HT 29(결장), MCF-7(유방), SiHA(자궁경부), B16F10( 마우스 피부 흑색종) 및 1개의 정상 인간 섬유아세포주.
RESULTS
All the synthesized compounds were screened for anti-cancer activity against six cancer cell lines, including A 549 (lung), DU 145 (prostate), HT 29 (colon), MCF-7 (breast), SiHA (cervical), B16F10 (mouse skin melanoma) and one normal human fibroblast cell lines.
결과 합성된 모든 화합물은 A 549(폐), DU 145(전립선), HT 29(결장), MCF-7(유방), SiHA(자궁경부), B16F10( 마우스 피부 흑색종) 및 1개의 정상 인간 섬유아세포주.
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In silico studies, a preliminary screening method for predicting the anti-cancer activity was performed for the synthesized compounds (3a-m) against Src, Alb tyrosine kinase and homology model protein (PDB ID: 4csv).
In silico 연구에서는 합성된 화합물(3a-m)에 대해 Src, Alb tyrosine kinase 및 homology model protein(PDB ID: 4csv)에 대한 예비 스크리닝 방법을 수행하였다.
In silico studies, a preliminary screening method for predicting the anti-cancer activity was performed for the synthesized compounds (3a-m) against Src, Alb tyrosine kinase and homology model protein (PDB ID: 4csv).
In silico 연구에서는 합성된 화합물(3a-m)에 대해 Src, Alb tyrosine kinase 및 homology model protein(PDB ID: 4csv)에 대한 예비 스크리닝 방법을 수행하였다.
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Synthesized Compounds sentence examples within α glucosidase inhibitory
The results indicated that all the synthesized compounds showed a substantial α-glucosidase inhibitory potential (IC50 between 3-78 µg/mL) compared to acarbose (IC50 = 16.
결과는 합성된 모든 화합물이 아카보스(IC50 = 16)에 비해 상당한 α-글루코시다제 억제 가능성(3-78 μg/mL 사이의 IC50)을 나타냄을 나타냅니다.
The results indicated that all the synthesized compounds showed a substantial α-glucosidase inhibitory potential (IC50 between 3-78 µg/mL) compared to acarbose (IC50 = 16.
결과는 합성된 모든 화합물이 아카보스(IC50 = 16)에 비해 상당한 α-글루코시다제 억제 가능성(3-78 μg/mL 사이의 IC50)을 나타냄을 나타냅니다.
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An in vitro α-glucosidase inhibitory assay of synthesized compounds was then carried out, and the structure-activity relationship of these compounds was conducted.
그런 다음 합성된 화합물의 시험관 내 α-글루코시다아제 억제 분석을 수행하고 이들 화합물의 구조-활성 관계를 수행했습니다.
An in vitro α-glucosidase inhibitory assay of synthesized compounds was then carried out, and the structure-activity relationship of these compounds was conducted.
그런 다음 합성된 화합물의 시험관 내 α-글루코시다아제 억제 분석을 수행하고 이들 화합물의 구조-활성 관계를 수행했습니다.
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Synthesized Compounds sentence examples within four human cancer
The synthesized compounds were characterized, and their cytotoxicity was evaluated against four human cancer cell lines using the MTT assay.
합성된 화합물을 특성화하고 MTT 분석을 사용하여 4개의 인간 암 세포주에 대해 세포 독성을 평가했습니다.
The synthesized compounds were characterized, and their cytotoxicity was evaluated against four human cancer cell lines using the MTT assay.
합성된 화합물을 특성화하고 MTT 분석을 사용하여 4개의 인간 암 세포주에 대해 세포 독성을 평가했습니다.
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The synthesized compounds were tested for their anticancer activity against four human cancer cell lines such as MCF-7 (breast), A549 (lung), DU-145 (prostate), and MDA MB-231 (breast) by MTT assay using etoposide as standard drug.
합성된 화합물은 MCF-7(유방), A549(폐), DU-145(전립선), MDA MB-231(유방)과 같은 4가지 인간 암 세포주에 대한 항암 활성을 에토포사이드를 사용하여 MTT 분석으로 테스트했습니다. 표준 약물.
The synthesized compounds were tested for their anticancer activity against four human cancer cell lines such as MCF-7 (breast), A549 (lung), DU-145 (prostate), and MDA MB-231 (breast) by MTT assay using etoposide as standard drug.
합성된 화합물은 MCF-7(유방), A549(폐), DU-145(전립선), MDA MB-231(유방)과 같은 4가지 인간 암 세포주에 대한 항암 활성을 에토포사이드를 사용하여 MTT 분석으로 테스트했습니다. 표준 약물.
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Synthesized Compounds sentence examples within vitro herbicidal activity
All synthesized compounds (4a-4i) were characterized by using 1HNMR and FTIR spectral techniques and evaluated for in vitro herbicidal activity against Raphanus sativus L.
합성된 모든 화합물(4a-4i)은 1HNMR 및 FTIR 스펙트럼 기술을 사용하여 특성화되었고 Raphanus sativus L에 대한 시험관 내 제초 활성에 대해 평가되었습니다.
All synthesized compounds (4a-4i) were characterized by using 1HNMR and FTIR spectral techniques and evaluated for in vitro herbicidal activity against Raphanus sativus L.
합성된 모든 화합물(4a-4i)은 1HNMR 및 FTIR 스펙트럼 기술을 사용하여 특성화되었고 Raphanus sativus L에 대한 시험관 내 제초 활성에 대해 평가되었습니다.
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All synthesized compounds (3a-3h) were characterized by 1HNMR, FTIR and CHN spectral techniques and tested for in vitro herbicidal activity against Raphanus sativus L.
합성된 모든 화합물(3a-3h)은 1HNMR, FTIR 및 CHN 스펙트럼 기술로 특성화되었으며 Raphanus sativus L에 대한 시험관 내 제초 활성에 대해 테스트되었습니다.
All synthesized compounds (3a-3h) were characterized by 1HNMR, FTIR and CHN spectral techniques and tested for in vitro herbicidal activity against Raphanus sativus L.
합성된 모든 화합물(3a-3h)은 1HNMR, FTIR 및 CHN 스펙트럼 기술로 특성화되었으며 Raphanus sativus L에 대한 시험관 내 제초 활성에 대해 테스트되었습니다.
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Synthesized Compounds sentence examples within free radical scavenging
The synthesized compounds were subjected to evaluation of central analgesic, anti-inflammatory, cytotoxicity, antimicrobial and antioxidant activities by radiant heat induced tail flicking, carrageenan induced rat paw edema inhibition, brine shrimp lethality bioassay, disc diffusion and DPPH free radical scavenging methods, respectively.
합성된 화합물은 복사열 유도 꼬리 튕김, 카라기난 유도 쥐 발 부종 억제, 브라인 쉬림프 치사성 생물 검정, 디스크 확산 및 DPPH 자유 라디칼 소거법에 의해 중추 진통, 항염증, 세포 독성, 항균 및 항산화 활성을 각각 평가했습니다. .
The synthesized compounds were subjected to evaluation of central analgesic, anti-inflammatory, cytotoxicity, antimicrobial and antioxidant activities by radiant heat induced tail flicking, carrageenan induced rat paw edema inhibition, brine shrimp lethality bioassay, disc diffusion and DPPH free radical scavenging methods, respectively.
합성된 화합물은 복사열 유도 꼬리 튕김, 카라기난 유도 쥐 발 부종 억제, 브라인 쉬림프 치사성 생물 검정, 디스크 확산 및 DPPH 자유 라디칼 소거법에 의해 중추 진통, 항염증, 세포 독성, 항균 및 항산화 활성을 각각 평가했습니다. .
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The antioxidant effect of the synthesized compounds was tested in vitro using the free radical scavenging power (DPPH) and reducing power (FRAP) tests.
합성된 화합물의 항산화 효과는 자유 라디칼 소거력(DPPH) 및 환원력(FRAP) 테스트를 사용하여 시험관 내에서 테스트되었습니다.
The antioxidant effect of the synthesized compounds was tested in vitro using the free radical scavenging power (DPPH) and reducing power (FRAP) tests.
합성된 화합물의 항산화 효과는 자유 라디칼 소거력(DPPH) 및 환원력(FRAP) 테스트를 사용하여 시험관 내에서 테스트되었습니다.
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Synthesized Compounds sentence examples within human tumor cell
All synthesized compounds were evaluated by the National Cancer Institute (NCI, USA) against 60 human tumor cell lines.
합성된 모든 화합물은 60개의 인간 종양 세포주에 대해 국립 암 연구소(National Cancer Institute, NCI, USA)에 의해 평가되었습니다.
All synthesized compounds were evaluated by the National Cancer Institute (NCI, USA) against 60 human tumor cell lines.
합성된 모든 화합물은 60개의 인간 종양 세포주에 대해 국립 암 연구소(National Cancer Institute, NCI, USA)에 의해 평가되었습니다.
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The synthesized compounds were evaluated for their cytotoxic activity against the NCI-60 human tumor cell line panel.
합성된 화합물을 NCI-60 인간 종양 세포주 패널에 대한 세포독성 활성에 대해 평가하였다.
The synthesized compounds were evaluated for their cytotoxic activity against the NCI-60 human tumor cell line panel.
합성된 화합물을 NCI-60 인간 종양 세포주 패널에 대한 세포독성 활성에 대해 평가하였다.
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Synthesized Compounds sentence examples within small cell lung
The cytotoxic activity of the newly synthesized compounds was evaluated against the human kidney epithelial T293 cell line, normal lung cell lines WI-38, non-small cell lung cancer A549 and NCI-H157 cell lines using MTT.
새로 합성된 화합물의 세포독성 활성은 MTT를 사용하여 인간 신장 상피 T293 세포주, 정상 폐 세포주 WI-38, 비소세포성 폐암 A549 및 NCI-H157 세포주에 대해 평가되었습니다.
The cytotoxic activity of the newly synthesized compounds was evaluated against the human kidney epithelial T293 cell line, normal lung cell lines WI-38, non-small cell lung cancer A549 and NCI-H157 cell lines using MTT.
새로 합성된 화합물의 세포독성 활성은 MTT를 사용하여 인간 신장 상피 T293 세포주, 정상 폐 세포주 WI-38, 비소세포성 폐암 A549 및 NCI-H157 세포주에 대해 평가되었습니다.
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We also investigated the antitumor activity of these synthesized compounds in small cell lung cancer (SCLC), and the results show that compounds 3d and 4s exhibit high anticancer potency against SCLC cells.
우리는 또한 소세포 폐암(SCLC)에서 합성된 화합물의 항종양 활성을 조사했으며, 결과는 화합물 3d 및 4s가 SCLC 세포에 대해 높은 항암 효능을 나타내는 것으로 나타났습니다.
We also investigated the antitumor activity of these synthesized compounds in small cell lung cancer (SCLC), and the results show that compounds 3d and 4s exhibit high anticancer potency against SCLC cells.
우리는 또한 소세포 폐암(SCLC)에서 합성된 화합물의 항종양 활성을 조사했으며, 결과는 화합물 3d 및 4s가 SCLC 세포에 대해 높은 항암 효능을 나타내는 것으로 나타났습니다.
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Synthesized Compounds sentence examples within minimum inhibitory concentration
The synthesized compounds' antifungal investigations on Aspergillus niger and Candida albicans fungus were evaluated using their Minimum Inhibitory Concentration values.
Aspergillus niger 및 Candida albicans 곰팡이에 대한 합성 화합물의 항진균 조사는 최소 억제 농도 값을 사용하여 평가되었습니다.
The synthesized compounds' antifungal investigations on Aspergillus niger and Candida albicans fungus were evaluated using their Minimum Inhibitory Concentration values.
Aspergillus niger 및 Candida albicans 곰팡이에 대한 합성 화합물의 항진균 조사는 최소 억제 농도 값을 사용하여 평가되었습니다.
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Among the synthesized compounds, 20–31 showed minimum inhibitory concentration (MIC) values of 1–64 µg/mL in vitro against HA-MRSA 18–19, 18–20, and S.
합성된 화합물 중 20-31은 HA-MRSA 18-19, 18-20 및 S에 대해 시험관 내에서 1-64 µg/mL의 최소 억제 농도(MIC) 값을 나타냈습니다.
Among the synthesized compounds, 20–31 showed minimum inhibitory concentration (MIC) values of 1–64 µg/mL in vitro against HA-MRSA 18–19, 18–20, and S.
합성된 화합물 중 20-31은 HA-MRSA 18-19, 18-20 및 S에 대해 시험관 내에서 1-64 µg/mL의 최소 억제 농도(MIC) 값을 나타냈습니다.
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Synthesized Compounds sentence examples within α amylase inhibitory
All synthesized compounds were characterized using different spectroscopic methods and evaluated for their α-amylase inhibitory activities.
합성된 모든 화합물은 다른 분광법을 사용하여 특성화되었고 α-아밀라아제 억제 활성에 대해 평가되었습니다.
All synthesized compounds were characterized using different spectroscopic methods and evaluated for their α-amylase inhibitory activities.
합성된 모든 화합물은 다른 분광법을 사용하여 특성화되었고 α-아밀라아제 억제 활성에 대해 평가되었습니다.
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All the synthesized compounds (3a–h) have exhibited higher in vitro α-amylase inhibitory activity than the standard acarbose, with 3f, 3g and 3h showing the better activity.
합성된 모든 화합물(3a-h)은 표준 acarbose보다 시험관 내 α-아밀라아제 억제 활성이 더 높았으며 3f, 3g 및 3h가 더 나은 활성을 나타냅니다.
All the synthesized compounds (3a–h) have exhibited higher in vitro α-amylase inhibitory activity than the standard acarbose, with 3f, 3g and 3h showing the better activity.
합성된 모든 화합물(3a-h)은 표준 acarbose보다 시험관 내 α-아밀라아제 억제 활성이 더 높았으며 3f, 3g 및 3h가 더 나은 활성을 나타냅니다.
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Synthesized Compounds sentence examples within cell line panel
Anticancer activities of synthesized compounds were investigated at the National Cancer Institute (NCI) against NCI 60 cell line panel, results showed good to notable anticancer activity.
합성된 화합물의 항암 활성을 NCI 60 세포주 패널에 대해 국립 암 연구소(National Cancer Institute, NCI)에서 조사한 결과, 우수한 항암 활성을 나타내었다.
Anticancer activities of synthesized compounds were investigated at the National Cancer Institute (NCI) against NCI 60 cell line panel, results showed good to notable anticancer activity.
합성된 화합물의 항암 활성을 NCI 60 세포주 패널에 대해 국립 암 연구소(National Cancer Institute, NCI)에서 조사한 결과, 우수한 항암 활성을 나타내었다.
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The one‐dose (10 µM) anticancer screening of the synthesized compounds in the NCI‐60 cell line panel revealed that the substituents have a significant role in the activity.
NCI-60 세포주 패널에서 합성된 화합물의 1회 용량(10 μM) 항암 스크리닝은 치환기가 활성에 중요한 역할을 하는 것으로 나타났습니다.
The one‐dose (10 µM) anticancer screening of the synthesized compounds in the NCI‐60 cell line panel revealed that the substituents have a significant role in the activity.
NCI-60 세포주 패널에서 합성된 화합물의 1회 용량(10 μM) 항암 스크리닝은 치환기가 활성에 중요한 역할을 하는 것으로 나타났습니다.
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Synthesized Compounds sentence examples within three cancer cell
All the new synthesized compounds were biologically evaluated in vitro for their cytotoxic activities against a panel of three cancer cell lines namely, HepG-2, MCF-7, and HCT-116.
새로 합성된 모든 화합물은 HepG-2, MCF-7 및 HCT-116과 같은 3가지 암 세포주 패널에 대한 세포독성 활성에 대해 시험관 내에서 생물학적으로 평가되었습니다.
All the new synthesized compounds were biologically evaluated in vitro for their cytotoxic activities against a panel of three cancer cell lines namely, HepG-2, MCF-7, and HCT-116.
새로 합성된 모든 화합물은 HepG-2, MCF-7 및 HCT-116과 같은 3가지 암 세포주 패널에 대한 세포독성 활성에 대해 시험관 내에서 생물학적으로 평가되었습니다.
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Specifically, we designed and synthesized a series of TPP-thiazole derivatives and revealed by the MTT assay that most synthesized compounds effectively inhibited three cancer cell lines (HeLa, PC3 and MCF-7).
구체적으로, 우리는 일련의 TPP-티아졸 유도체를 설계 및 합성했으며, 대부분의 합성된 화합물이 3가지 암세포주(HeLa, PC3 및 MCF-7)를 효과적으로 억제한다는 것을 MTT 분석에 의해 밝혀냈습니다.
Specifically, we designed and synthesized a series of TPP-thiazole derivatives and revealed by the MTT assay that most synthesized compounds effectively inhibited three cancer cell lines (HeLa, PC3 and MCF-7).
구체적으로, 우리는 일련의 TPP-티아졸 유도체를 설계 및 합성했으며, 대부분의 합성된 화합물이 3가지 암세포주(HeLa, PC3 및 MCF-7)를 효과적으로 억제한다는 것을 MTT 분석에 의해 밝혀냈습니다.
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Synthesized Compounds sentence examples within human colorectal adenocarcinoma
The synthesized compounds were tested for in vitro COX‐1/COX‐2 inhibition and cell toxicity against human colorectal adenocarcinoma cell lines HT‐29.
합성된 화합물을 시험관 내 COX-1/COX-2 억제 및 인간 결장직장 선암종 세포주 HT-29에 대한 세포 독성에 대해 테스트했습니다.
The synthesized compounds were tested for in vitro COX‐1/COX‐2 inhibition and cell toxicity against human colorectal adenocarcinoma cell lines HT‐29.
합성된 화합물을 시험관 내 COX-1/COX-2 억제 및 인간 결장직장 선암종 세포주 HT-29에 대한 세포 독성에 대해 테스트했습니다.
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In addition, cytotoxic effects of the synthesized compounds on human colorectal adenocarcinoma (HT-29; HTB-38), human breast adenocarcinoma (MCF7; HTB-22), human prostate adenocarcinoma (PC3; CRL-1435) and human healthy skin fibroblast (CCD-986Sk; CRL-1947) cell lines were examined.
또한 인간 결장직장 선암종(HT-29; HTB-38), 인간 유방 선암종(MCF7; HTB-22), 인간 전립선 선암종(PC3; CRL-1435) 및 인간의 건강한 피부 섬유아세포( CCD-986Sk; CRL-1947) 세포주를 조사했습니다.
In addition, cytotoxic effects of the synthesized compounds on human colorectal adenocarcinoma (HT-29; HTB-38), human breast adenocarcinoma (MCF7; HTB-22), human prostate adenocarcinoma (PC3; CRL-1435) and human healthy skin fibroblast (CCD-986Sk; CRL-1947) cell lines were examined.
또한 인간 결장직장 선암종(HT-29; HTB-38), 인간 유방 선암종(MCF7; HTB-22), 인간 전립선 선암종(PC3; CRL-1435) 및 인간의 건강한 피부 섬유아세포( CCD-986Sk; CRL-1947) 세포주를 조사했습니다.
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Synthesized Compounds sentence examples within 2 yl 2
The anticancer activity of the synthesized compounds was determined using MTT (3-(4, 5- dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide) reduction assay against MCF-7 cells, and then the minimum inhibitory concentration (IC50) was determined with the reference of the standard drug tamoxifen.
합성된 화합물의 항암 활성은 MCF-7 세포에 대한 MTT(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) 환원 분석법을 이용하여 측정한 후 최소 억제 농도(IC50) ) 표준 약물 타목시펜을 기준으로 결정되었습니다.
The anticancer activity of the synthesized compounds was determined using MTT (3-(4, 5- dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide) reduction assay against MCF-7 cells, and then the minimum inhibitory concentration (IC50) was determined with the reference of the standard drug tamoxifen.
합성된 화합물의 항암 활성은 MCF-7 세포에 대한 MTT(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) 환원 분석법을 이용하여 측정한 후 최소 억제 농도(IC50) ) 표준 약물 타목시펜을 기준으로 결정되었습니다.
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In order to evaluate their antibacterial potential, the antibacterial assay of synthesized compounds 6a–j was performed against MTCC strains, wherein compounds 6d (3-(4-methyl-5-(4-(((4-nitrophenyl)amino)methyl)-5-thioxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)thiazol-2-yl)-2-phenylquinazolin-4(3H)-one) (Escherichia coli, MIC = 100 µg mL−1) and 6e (3-(5-(4-(((2-chlorophenyl)amino)methyl)-5-thioxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)-4-methylthiazol-2-yl)-2-phenylquinazolin-4(3H)-one) (E.
항균 가능성을 평가하기 위해 합성된 화합물 6a-j의 항균 분석을 MTCC 균주에 대해 수행했습니다. -5-티옥소-4,5-디히드로-1,3,4-옥사디아졸-2-일)티아졸-2-일)-2-페닐퀴나졸린-4(3H)-온) (대장균, MIC = 100 µg mL -1) 및 6e(3-(5-(4-(((2-클로로페닐)아미노)메틸)-5-티옥소-4,5-디하이드로-1,3,4-옥사디아졸-2-일)-4 -메틸티아졸-2-일)-2-페닐퀴나졸린-4(3H)-온)(E.
In order to evaluate their antibacterial potential, the antibacterial assay of synthesized compounds 6a–j was performed against MTCC strains, wherein compounds 6d (3-(4-methyl-5-(4-(((4-nitrophenyl)amino)methyl)-5-thioxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)thiazol-2-yl)-2-phenylquinazolin-4(3H)-one) (Escherichia coli, MIC = 100 µg mL−1) and 6e (3-(5-(4-(((2-chlorophenyl)amino)methyl)-5-thioxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)-4-methylthiazol-2-yl)-2-phenylquinazolin-4(3H)-one) (E.
항균 가능성을 평가하기 위해 합성된 화합물 6a-j의 항균 분석을 MTCC 균주에 대해 수행했습니다. -5-티옥소-4,5-디히드로-1,3,4-옥사디아졸-2-일)티아졸-2-일)-2-페닐퀴나졸린-4(3H)-온) (대장균, MIC = 100 µg mL -1) 및 6e(3-(5-(4-(((2-클로로페닐)아미노)메틸)-5-티옥소-4,5-디하이드로-1,3,4-옥사디아졸-2-일)-4 -메틸티아졸-2-일)-2-페닐퀴나졸린-4(3H)-온)(E.
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Synthesized Compounds sentence examples within six cancer cell
Selected compounds among the synthesized compounds were tested against six cancer cell lines where most of them gave high inhibitions; especially compounds 3b, 3c, 6b, 6c, 6d, 6f, 6i, 6m, 6n, 8b, 14a, 15 and 16 being the most cytotoxic compounds.
합성된 화합물 중 선택된 화합물은 대부분이 높은 억제를 나타내는 6개의 암세포주에 대해 테스트되었습니다. 특히 화합물 3b, 3c, 6b, 6c, 6d, 6f, 6i, 6m, 6n, 8b, 14a, 15 및 16이 가장 세포독성이 높은 화합물입니다.
Selected compounds among the synthesized compounds were tested against six cancer cell lines where most of them gave high inhibitions; especially compounds 3b, 3c, 6b, 6c, 6d, 6f, 6i, 6m, 6n, 8b, 14a, 15 and 16 being the most cytotoxic compounds.
합성된 화합물 중 선택된 화합물은 대부분이 높은 억제를 나타내는 6개의 암세포주에 대해 테스트되었습니다. 특히 화합물 3b, 3c, 6b, 6c, 6d, 6f, 6i, 6m, 6n, 8b, 14a, 15 및 16이 가장 세포독성이 높은 화합물입니다.
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Synthesized Compounds sentence examples within 12 dihydro 3β
Among the synthesized compounds nine are novel compounds including six deuterated analogs/isotopologs which are (1,3-2H)-1,2-dihydro-3β-hydroxyazadiradione (9), (1,3,16-2H)-1,2-dihydro-3β-16β-dihydroxyazadiradione (10), 3β-hydroxyazadiradione (11), 3β-16β-dihydroxyazadiradione (12), (3-2H)-3β-hydroxyazadiradione (13), (3,16-2H)-3β-16β-dihydroxyazadiradione (14), (1,3,7-2H)-1,2-dihydro-3β-hydroxy-7-deacetylazadiradione (15), 1,2,20,21,22,23-hexahydroazadiradione (17), and (1,3-2H)-1,2-dihydro-3β-hydroxygedunin (29).
합성된 화합물 중 9개는 (1,3-2H)-1,2-dihydro-3β-hydroxyazadiradione (9), (1,3,16-2H)-1,2인 6개의 중수소화 유사체/동위원소를 포함하는 신규 화합물입니다. -디히드로-3β-16β-디히드록시아자디라디온(10), 3β-히드록시아자디라디온(11), 3β-16β-디히드록시아자디라디온(12), (3-2H)-3β-히드록시아자디라디온(13), (3,16-2H)-3β -16β-디히드록시아자디라디온(14), (1,3,7-2H)-1,2-디히드로-3β-히드록시-7-데아세틸아자디라디온(15), 1,2,20,21,22,23-헥사히드로아자디라디온(17) ), 및 (1,3-2H)-1,2-디히드로-3β-히드록시게두닌(29).
Among the synthesized compounds nine are novel compounds including six deuterated analogs/isotopologs which are (1,3-2H)-1,2-dihydro-3β-hydroxyazadiradione (9), (1,3,16-2H)-1,2-dihydro-3β-16β-dihydroxyazadiradione (10), 3β-hydroxyazadiradione (11), 3β-16β-dihydroxyazadiradione (12), (3-2H)-3β-hydroxyazadiradione (13), (3,16-2H)-3β-16β-dihydroxyazadiradione (14), (1,3,7-2H)-1,2-dihydro-3β-hydroxy-7-deacetylazadiradione (15), 1,2,20,21,22,23-hexahydroazadiradione (17), and (1,3-2H)-1,2-dihydro-3β-hydroxygedunin (29).
합성된 화합물 중 9개는 (1,3-2H)-1,2-dihydro-3β-hydroxyazadiradione (9), (1,3,16-2H)-1,2인 6개의 중수소화 유사체/동위원소를 포함하는 신규 화합물입니다. -디히드로-3β-16β-디히드록시아자디라디온(10), 3β-히드록시아자디라디온(11), 3β-16β-디히드록시아자디라디온(12), (3-2H)-3β-히드록시아자디라디온(13), (3,16-2H)-3β -16β-디히드록시아자디라디온(14), (1,3,7-2H)-1,2-디히드로-3β-히드록시-7-데아세틸아자디라디온(15), 1,2,20,21,22,23-헥사히드로아자디라디온(17) ), 및 (1,3-2H)-1,2-디히드로-3β-히드록시게두닌(29).
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Synthesized Compounds sentence examples within cell lines namely
All the new synthesized compounds were biologically evaluated for their in vitro cytotoxicity against a panel of five cell lines namely human colorectal adenocarcinoma cell line DLD1, human cervical cancer cell line Hela, human leukemia cell line K562, human pancreatic cancer cell line Suit-2 and human hepatocellular carcinoma cell line HepG2.
새로 합성된 모든 화합물은 인간 결장직장 선암종 세포주 DLD1, 인간 자궁경부암 세포주 Hela, 인간 백혈병 세포주 K562, 인간 췌장암 세포주 Suit-2 및 인간 간세포 암종 세포주 HepG2.
All the new synthesized compounds were biologically evaluated for their in vitro cytotoxicity against a panel of five cell lines namely human colorectal adenocarcinoma cell line DLD1, human cervical cancer cell line Hela, human leukemia cell line K562, human pancreatic cancer cell line Suit-2 and human hepatocellular carcinoma cell line HepG2.
새로 합성된 모든 화합물은 인간 결장직장 선암종 세포주 DLD1, 인간 자궁경부암 세포주 Hela, 인간 백혈병 세포주 K562, 인간 췌장암 세포주 Suit-2 및 인간 간세포 암종 세포주 HepG2.
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Synthesized Compounds sentence examples within resolution mass spectrometry
The structure of the newly synthesized compounds was established by means of elemental analysis; high-resolution mass spectrometry; 1H, 13C NMR, IR and UV spectroscopy; and mass spectrometry.
새로 합성된 화합물의 구조는 원소 분석을 통해 확립되었습니다. 고해상도 질량분석기; 1H, 13C NMR, IR 및 UV 분광법; 및 질량 분석법.
The structure of the newly synthesized compounds was established by means of elemental analysis; high-resolution mass spectrometry; 1H, 13C NMR, IR and UV spectroscopy; and mass spectrometry.
새로 합성된 화합물의 구조는 원소 분석을 통해 확립되었습니다. 고해상도 질량분석기; 1H, 13C NMR, IR 및 UV 분광법; 및 질량 분석법.
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Synthesized Compounds sentence examples within Newly Synthesized Compounds
The newly synthesized compounds have been targeted due to their bioactivity in wide pharmaceutical uses, especially, as anti-proliferative agents.
새로 합성된 화합물은 광범위한 제약 용도, 특히 항증식제로서의 생물학적 활성으로 인해 표적이 되었습니다.
The newly synthesized compounds have been targeted due to their bioactivity in wide pharmaceutical uses, especially, as anti-proliferative agents.
새로 합성된 화합물은 광범위한 제약 용도, 특히 항증식제로서의 생물학적 활성으로 인해 표적이 되었습니다.
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These newly synthesized compounds may be used as novel inhibitors of nuclear receptors with potential therapeutic applications in control of cancer.
이 새로 합성된 화합물은 암 조절에 잠재적인 치료 응용이 가능한 새로운 핵 수용체 억제제로 사용될 수 있습니다.
These newly synthesized compounds may be used as novel inhibitors of nuclear receptors with potential therapeutic applications in control of cancer.
이 새로 합성된 화합물은 암 조절에 잠재적인 치료 응용이 가능한 새로운 핵 수용체 억제제로 사용될 수 있습니다.
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Synthesized Compounds sentence examples within All Synthesized Compounds
All synthesized compounds to some extent have shown good antimicrobial activity against different microbial strains that had been extracted by inhibiting cell wall synthesis.
합성된 모든 화합물은 세포벽 합성을 억제하여 추출된 다양한 미생물 균주에 대해 어느 정도 우수한 항균 활성을 나타냈습니다.
All synthesized compounds to some extent have shown good antimicrobial activity against different microbial strains that had been extracted by inhibiting cell wall synthesis.
합성된 모든 화합물은 세포벽 합성을 억제하여 추출된 다양한 미생물 균주에 대해 어느 정도 우수한 항균 활성을 나타냈습니다.
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All synthesized compounds inhibited both cholinesterases at nanomolar level.
합성된 모든 화합물은 나노몰 수준에서 두 콜린에스테라제를 모두 억제했습니다.
All synthesized compounds inhibited both cholinesterases at nanomolar level.
합성된 모든 화합물은 나노몰 수준에서 두 콜린에스테라제를 모두 억제했습니다.
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Synthesized Compounds sentence examples within New Synthesized Compounds
From the initial concentration of the new synthesized compounds of 1 mg/ml, a series of two-fold serial dilutions were prepared in Mueller–Hinton broth in a volume of 1 ml.
1mg/ml의 새로운 합성 화합물의 초기 농도에서 1ml 부피의 Mueller-Hinton 국물에서 일련의 2배 연속 희석액을 준비했습니다.
From the initial concentration of the new synthesized compounds of 1 mg/ml, a series of two-fold serial dilutions were prepared in Mueller–Hinton broth in a volume of 1 ml.
1mg/ml의 새로운 합성 화합물의 초기 농도에서 1ml 부피의 Mueller-Hinton 국물에서 일련의 2배 연속 희석액을 준비했습니다.
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All the new synthesized compounds were evaluated for insecticidal activities on Mythimna separata Walker and Plutella xylostella L.
새로 합성된 모든 화합물은 Mythimna separata Walker와 Plutella xylostella L에 대한 살충 활성을 평가했습니다.
All the new synthesized compounds were evaluated for insecticidal activities on Mythimna separata Walker and Plutella xylostella L.
새로 합성된 모든 화합물은 Mythimna separata Walker와 Plutella xylostella L에 대한 살충 활성을 평가했습니다.
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Synthesized Compounds sentence examples within Chemically Synthesized Compounds
Cancer chemoprevention by definition means making use of bioactive or chemically synthesized compounds for inhibition and prevention of the cancer relapse.
정의에 의한 암 화학 예방은 암 재발의 억제 및 예방을 위해 생리활성 또는 화학적으로 합성된 화합물을 사용하는 것을 의미합니다.
Cancer chemoprevention by definition means making use of bioactive or chemically synthesized compounds for inhibition and prevention of the cancer relapse.
정의에 의한 암 화학 예방은 암 재발의 억제 및 예방을 위해 생리활성 또는 화학적으로 합성된 화합물을 사용하는 것을 의미합니다.
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Furthermore, naringin has shown potential to become an alternative as traditional anti-inflammatory drug, because it exerts less side effects than chemically synthesized compounds.
또한, 나린진은 화학적으로 합성된 화합물보다 부작용이 적기 때문에 전통적인 항염증제로서의 대안이 될 가능성을 보여주었다.
Furthermore, naringin has shown potential to become an alternative as traditional anti-inflammatory drug, because it exerts less side effects than chemically synthesized compounds.
또한, 나린진은 화학적으로 합성된 화합물보다 부작용이 적기 때문에 전통적인 항염증제로서의 대안이 될 가능성을 보여주었다.
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Synthesized Compounds sentence examples within Novel Synthesized Compounds
, IR, 1H NMR, 13C NMR and Mass spectrometry were used to determine structure of novel synthesized compounds.
, IR, 1H NMR, 13C NMR 및 질량 분석법을 사용하여 신규 합성 화합물의 구조를 결정했습니다.
, IR, 1H NMR, 13C NMR and Mass spectrometry were used to determine structure of novel synthesized compounds.
, IR, 1H NMR, 13C NMR 및 질량 분석법을 사용하여 신규 합성 화합물의 구조를 결정했습니다.
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NPS are novel synthesized compounds that are being produced by a slight alteration/modification in the chemical structure of existing illegal substances, already registered in the European Union (EU).
NPS는 이미 유럽연합(EU)에 등록된 기존 불법 물질의 화학 구조를 약간 변경/변형하여 생산되는 새로운 합성 화합물입니다.
NPS are novel synthesized compounds that are being produced by a slight alteration/modification in the chemical structure of existing illegal substances, already registered in the European Union (EU).
NPS는 이미 유럽연합(EU)에 등록된 기존 불법 물질의 화학 구조를 약간 변경/변형하여 생산되는 새로운 합성 화합물입니다.
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Synthesized Compounds sentence examples within Previously Synthesized Compounds
We investigated by molecular docking the potential biological activity of previously synthesized compounds containing acridine and pyrrolidine-2,5-diones fragments in their structure, as well as synthesized in this work N’-hydroxy-1,2,3,4,5,6,7,8-octahydroacridine-4-carboximidamide.
우리는 구조에 아크리딘 및 피롤리딘-2,5-디온 단편을 포함하는 이전에 합성된 화합물의 잠재적인 생물학적 활성을 분자 도킹으로 조사했을 뿐만 아니라 이 연구에서 합성한 N'-히드록시-1,2,3,4,5, 6,7,8-옥타히드로아크리딘-4-카르복시이미드아미드.
We investigated by molecular docking the potential biological activity of previously synthesized compounds containing acridine and pyrrolidine-2,5-diones fragments in their structure, as well as synthesized in this work N’-hydroxy-1,2,3,4,5,6,7,8-octahydroacridine-4-carboximidamide.
우리는 구조에 아크리딘 및 피롤리딘-2,5-디온 단편을 포함하는 이전에 합성된 화합물의 잠재적인 생물학적 활성을 분자 도킹으로 조사했을 뿐만 아니라 이 연구에서 합성한 N'-히드록시-1,2,3,4,5, 6,7,8-옥타히드로아크리딘-4-카르복시이미드아미드.
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Previously synthesized compounds with diazotricyclodecane cores (DTDs) have shown their effectiveness in binding opioid receptors.
이전에 합성된 diazotricyclodecane cores(DTDs) 화합물은 오피오이드 수용체에 결합하는 데 효과가 있는 것으로 나타났습니다.
Previously synthesized compounds with diazotricyclodecane cores (DTDs) have shown their effectiveness in binding opioid receptors.
이전에 합성된 diazotricyclodecane cores(DTDs) 화합물은 오피오이드 수용체에 결합하는 데 효과가 있는 것으로 나타났습니다.
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Synthesized Compounds sentence examples within Several Synthesized Compounds
RESULTS
Several synthesized compounds exhibited a significant biological effect by ameliorating the eye degeneration.
결과
합성된 여러 화합물은 눈의 변성을 개선함으로써 상당한 생물학적 효과를 나타냈습니다.
RESULTS
Several synthesized compounds exhibited a significant biological effect by ameliorating the eye degeneration.
결과 합성된 여러 화합물은 눈의 변성을 개선함으로써 상당한 생물학적 효과를 나타냈습니다.
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Also, several synthesized compounds were screened for their in vitro antimicrobial activities by employing the disk diffusion test on Gram-negative as well as Gram-positive bacteria.
또한, 그람-음성 및 그람-양성 세균에 대한 디스크 확산 시험을 사용하여 몇몇 합성된 화합물의 시험관내 항균 활성에 대해 스크리닝하였다.
Also, several synthesized compounds were screened for their in vitro antimicrobial activities by employing the disk diffusion test on Gram-negative as well as Gram-positive bacteria.
또한, 그람-음성 및 그람-양성 세균에 대한 디스크 확산 시험을 사용하여 몇몇 합성된 화합물의 시험관내 항균 활성에 대해 스크리닝하였다.
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Synthesized Compounds sentence examples within Two Synthesized Compounds
The magnetic performances of the two synthesized compounds reveal antiferromagnetic coupling between consecutive metal ions.
합성된 두 화합물의 자기 성능은 연속적인 금속 이온 사이의 반강자성 결합을 나타냅니다.
The magnetic performances of the two synthesized compounds reveal antiferromagnetic coupling between consecutive metal ions.
합성된 두 화합물의 자기 성능은 연속적인 금속 이온 사이의 반강자성 결합을 나타냅니다.
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The magnetic performances of two synthesized compounds reveal antiferromagnetic coupling between consecutive metal ions.
합성된 두 화합물의 자기 성능은 연속적인 금속 이온 사이의 반강자성 결합을 나타냅니다.
The magnetic performances of two synthesized compounds reveal antiferromagnetic coupling between consecutive metal ions.
합성된 두 화합물의 자기 성능은 연속적인 금속 이온 사이의 반강자성 결합을 나타냅니다.
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Synthesized Compounds sentence examples within synthesized compounds showed
The synthesized compounds showed strong bacteriostatic activity against a panel of both Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and two fungi.
합성된 화합물은 메티실린 내성 황색 포도구균(MRSA)과 2종의 진균을 포함하여 그람 양성 및 그람 음성 박테리아 패널에 대해 강력한 정균 활성을 나타냈다.
The synthesized compounds showed strong bacteriostatic activity against a panel of both Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and two fungi.
합성된 화합물은 메티실린 내성 황색 포도구균(MRSA)과 2종의 진균을 포함하여 그람 양성 및 그람 음성 박테리아 패널에 대해 강력한 정균 활성을 나타냈다.
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The synthesized compounds showed diverse antimicrobial profiles among which derivatives 2, 3 & 6 possessed enhanced activity in contrast to the ciprofloxacin.
합성된 화합물은 ciprofloxacin과 대조적으로 유도체 2, 3 및 6이 향상된 활성을 갖는 다양한 항균 프로파일을 보여주었습니다.
The synthesized compounds showed diverse antimicrobial profiles among which derivatives 2, 3 & 6 possessed enhanced activity in contrast to the ciprofloxacin.
합성된 화합물은 ciprofloxacin과 대조적으로 유도체 2, 3 및 6이 향상된 활성을 갖는 다양한 항균 프로파일을 보여주었습니다.
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Synthesized Compounds sentence examples within synthesized compounds exhibited
All the synthesized compounds exhibited cytotoxic effects against HeLa cells and compounds 3d displayed better activity (IC50) than the standard drug (doxorubicin).
합성된 모든 화합물은 HeLa 세포에 대해 세포독성 효과를 나타내었고 화합물 3d는 표준 약물(doxorubicin)보다 더 나은 활성(IC50)을 나타냈다.
All the synthesized compounds exhibited cytotoxic effects against HeLa cells and compounds 3d displayed better activity (IC50) than the standard drug (doxorubicin).
합성된 모든 화합물은 HeLa 세포에 대해 세포독성 효과를 나타내었고 화합물 3d는 표준 약물(doxorubicin)보다 더 나은 활성(IC50)을 나타냈다.
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All the compounds were screened against breast cancer (MCF-7 and MDA-MB231), skin cancer (A431) and normal prostate cell line (PNT2) in terms of cell viability and found that all the synthesized compounds exhibited in vitro antiproliferation toward the tested cancer cells.
모든 화합물을 유방암(MCF-7 및 MDA-MB231), 피부암(A431) 및 정상 전립선 세포주(PNT2)에 대해 세포 생존율 측면에서 스크리닝한 결과 합성된 모든 화합물이 시험관 내 항증식성을 나타내는 것으로 나타났습니다. 암세포.
All the compounds were screened against breast cancer (MCF-7 and MDA-MB231), skin cancer (A431) and normal prostate cell line (PNT2) in terms of cell viability and found that all the synthesized compounds exhibited in vitro antiproliferation toward the tested cancer cells.
모든 화합물을 유방암(MCF-7 및 MDA-MB231), 피부암(A431) 및 정상 전립선 세포주(PNT2)에 대해 세포 생존율 측면에서 스크리닝한 결과 합성된 모든 화합물이 시험관 내 항증식성을 나타내는 것으로 나타났습니다. 암세포.
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Synthesized Compounds sentence examples within synthesized compounds displayed
The synthesized compounds displayed good antiplasmodial activity with IC50 values ranging at 0.
합성된 화합물은 0 범위의 IC50 값으로 우수한 항염색체 활성을 나타냈습니다.
The synthesized compounds displayed good antiplasmodial activity with IC50 values ranging at 0.
합성된 화합물은 0 범위의 IC50 값으로 우수한 항염색체 활성을 나타냈습니다.
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Five of the synthesized compounds displayed good cytotoxic activity against two human cancer cell lines, KB and HepG2, with half maximal inhibitory concentration values in a range of 4–20 μM.
합성된 화합물 중 5개는 2개의 인간 암 세포주인 KB 및 HepG2에 대해 우수한 세포독성 활성을 나타내었으며 4-20μM 범위의 최대 억제 농도 값의 절반을 나타냅니다.
Five of the synthesized compounds displayed good cytotoxic activity against two human cancer cell lines, KB and HepG2, with half maximal inhibitory concentration values in a range of 4–20 μM.
합성된 화합물 중 5개는 2개의 인간 암 세포주인 KB 및 HepG2에 대해 우수한 세포독성 활성을 나타내었으며 4-20μM 범위의 최대 억제 농도 값의 절반을 나타냅니다.
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Synthesized Compounds sentence examples within synthesized compounds exhibit
Synthesized Compounds sentence examples within synthesized compounds toward
The enzyme inhibition potentials against all the synthesized compounds toward SphK1 were evaluated, and the results revealed that most of the studied compounds inhibited SphK1 effectively.
합성된 모든 화합물에 대한 SphK1에 대한 효소 억제 가능성을 평가한 결과, 연구된 대부분의 화합물이 SphK1을 효과적으로 억제하는 것으로 나타났다.
The enzyme inhibition potentials against all the synthesized compounds toward SphK1 were evaluated, and the results revealed that most of the studied compounds inhibited SphK1 effectively.
합성된 모든 화합물에 대한 SphK1에 대한 효소 억제 가능성을 평가한 결과, 연구된 대부분의 화합물이 SphK1을 효과적으로 억제하는 것으로 나타났다.
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A molecular docking study evaluated the affinity of the synthesized compounds towards the BRI1-BAK1 receptor from Arabidopsis thaliana and three of the docked compounds displayed a binding energy lower than brassinolide.
분자 도킹 연구는 Arabidopsis thaliana의 BRI1-BAK1 수용체에 대한 합성 화합물의 친화성을 평가했으며 도킹된 화합물 중 3개는 브라시놀리드보다 낮은 결합 에너지를 나타냈습니다.
A molecular docking study evaluated the affinity of the synthesized compounds towards the BRI1-BAK1 receptor from Arabidopsis thaliana and three of the docked compounds displayed a binding energy lower than brassinolide.
분자 도킹 연구는 Arabidopsis thaliana의 BRI1-BAK1 수용체에 대한 합성 화합물의 친화성을 평가했으며 도킹된 화합물 중 3개는 브라시놀리드보다 낮은 결합 에너지를 나타냈습니다.
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Synthesized Compounds 합성 화합물
Synthesized Compounds 합성 화합물
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