Superiority Trial(우월성 시험)란 무엇입니까?
Superiority Trial 우월성 시험 - Design, Setting, and Participants A randomized, controlled, nonblinded, superiority trial was conducted at 2 perinatal centers between May 9, 2017, and February 1, 2020. [1] A randomized trial to test if DHA can influence brain volume could still be done; however, because most preterm infants now receive DHA, it would need to be a superiority trial in which one group received a much larger amount of DHA. [2] The belief is roughly valid for noninferiority and equivalence trials with similar survival and censoring distributions between two groups, and for superiority trials with balanced group sizes. [3] Methods and analysis International, pragmatic, multicentre, randomised, superiority trial. [4] OPTIMAL‐REPERFUSION is an investigator‐initiated, prospective, multicenter, randomized, open‐label, superiority trial with blinded evaluation of outcomes. [5] The target sample size of this superiority trial is 120 patients, as this will provide 80% power at the 2. [6] Methods This randomised, multicentre, double-blind, adaptive-design, superiority trial was conducted in three USA medical centres. [7] Methods and analysis This is a randomised controlled hierarchical non-inferiority–superiority trial being conducted in ICUs across Nepal, Thailand and Singapore. [8] The target sample size of this superiority trial is 120 patients, as this will provide 80% power at the 2. [9] Design This is a parallel-group, unicentric, randomised, assessor-blinded, superiority trial with equal allocation ratio to evaluate and compare the effects of periodontal treatment on endothelial function, measured by a flow-mediated dilation of brachial artery, in patients with a recent ST-segment elevation myocardial infarction (STEMI). [10] Shortterm outcomes of complete mesocolic excision versus D2 dissection in patients undergoing laparoscopic colectomy for right colon cancer (RELARC): a randomised, controlled, phase 3, superiority trial. [11] The trial is designed as a superiority trial to test the hypothesis that rehabilitation (home-based telerehabilitation and home-based rehabilitation) is superior to no physical rehabilitation. [12] This is a randomized (1:1), 2 parallel-group, superiority trial with evaluator blinding and stratification according to center and methylphenidate treatment. [13] They randomized a total of 120 neonates against the calculated sample size of 174 neonates for a superiority trial and reported no significant difference in the incidence of RAP between the two groups. [14] Aim To discuss ethical issues related to a complex study (PROFID) involving the development of a new, partly artificial intelligence-based, prediction model to enable personalised decision-making about the implantation of an implantable cardioverter defibrillator (ICD) in postmyocardial infarction patients, and a parallel non-inferiority and superiority trial to test decision-making informed by that model. [15] Methods: Through some limited simulations and asymptotic power calculations, the authors compare the operating characteristics of restricted mean survival time and proportional hazards methods for analyzing both noninferiority and superiority trials under proportional hazardss to understand what relative power benefits there are when using restricted mean survival time methods for noninferiority testing. [16] Methods This is a multi-site, individually randomised, superiority trial with an embedded process evaluation and an economic analysis of cost-effectiveness. [17] Superiority trials investigating biologics have been rare until recently. [18] A two-arm, single-centre, superiority trial with stratified randomisation (1:1) and pre-post measures will be used to assess the effect of the intervention compared to standard care. [19] To demonstrate that long BPL RYGB is superior compared to short BPL RYGB in terms of weight loss and resolution of T2DM, the study is conducted as a superiority trial. [20] Design Prospective, randomised, 2 years, assessor-blind, multicentre, superiority trial. [21] In recent years superiority trials have often been replaced by equivalence or noninferiority trials. [22] The trial is designed as a superiority trial to test the hypothesis that rehabilitation (home-based telerehabilitation and home-based rehabilitation) is superior to no physical rehabilitation. [23] DESIGN Randomized, single-blinded, controlled, superiority trial. [24]디자인, 설정 및 참가자 2017년 5월 9일과 2020년 2월 1일 사이에 2개의 주산기 센터에서 무작위, 통제, 비맹검, 우월성 시험이 수행되었습니다. [1] DHA가 뇌 용적에 영향을 미칠 수 있는지 테스트하기 위한 무작위 시험은 여전히 수행될 수 있습니다. 그러나 대부분의 조산아가 현재 DHA를 투여받고 있기 때문에 한 그룹이 훨씬 더 많은 양의 DHA를 투여받는 우월성 시험이 필요합니다. [2] 이 믿음은 두 그룹 간의 생존 및 중도절단 분포가 유사한 비열등성 및 동등성 시험과 균형 잡힌 그룹 크기의 우월성 시험에 대해 대략적으로 유효합니다. [3] 방법 및 분석 국제, 실용, 다기관, 무작위, 우월성 시험. [4] OPTIMAL-REPERFUSION은 결과에 대한 맹검 평가가 포함된 연구자 주도, 전향적, 다기관, 무작위, 공개 라벨, 우월성 시험입니다. [5] 이 우월성 시험의 목표 표본 크기는 120명의 환자이며, 이는 2에서 80%의 검정력을 제공합니다. [6] 방법 이 무작위, 다기관, 이중 맹검, 적응 설계, 우월성 시험은 3개의 미국 의료 센터에서 수행되었습니다. [7] 방법 및 분석 이것은 네팔, 태국 및 싱가포르의 ICU에서 수행되는 무작위 통제 계층적 비열등성 시험입니다.