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Suppressor of cytokine signalling 3 (SOCS3) expressed in podocytes attenuates glomerulonephritis and suppresses autoantibody production in an imiquimod-induced lupus model


Porcine reproductive and respiratory syndrome virus increases SOCS3 production via activation of p38/AP-1 signaling pathway to promote viral replication.

Socs3 Expression sentence examples within Increased Socs3 Expression



CYT387 Inhibits the Hyperproliferative Potential of Fibroblast-like Synoviocytes via Modulation of IL-6/JAK1/STAT3 Signaling in Rheumatoid Arthritis.


MiR-221 affects proliferation and apoptosis of gastric cancer cells through targeting SOCS3.

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Paeoniflorin inhibits the macrophage-related rosacea-like inflammatory reaction through the suppressor of cytokine signaling 3-apoptosis signal-regulating kinase 1-p38 pathway


YY1 promotes SOCS3 expression to inhibit STAT3‑mediated neuroinflammation and neuropathic pain.



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AB0109 SYSTEMIC OVEREXPRESSION OF INTERLEUKIN-22 INDUCES EXPRESSION OF THE NEGATIVE IMMUNE-REGULATOR SOCS3 AND POTENTLY REDUCES COLLAGEN-INDUCED ARTHRITIS IN MICE


P086 Systemic overexpression of interleukin-22 induces expression of the negative immune-regulator SOCS3 and potently reduces collagen-induced arthritis in mice

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Involvement of EZH2 inhibition in lenalidomide and pomalidomide-mediated growth suppression in HTLV-1-infected cells.


TGF-β2 antagonizes IL-6-promoted cell survival

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EYA2 suppresses the progression of hepatocellular carcinoma via SOCS3-mediated blockade of JAK/STAT signaling


MiR-155 regulates the proliferation and apoptosis of pancreatic cancer cells through targeting SOCS3.

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Increased PARylation impacts the DNA methylation process in type 2 diabetes mellitus


Gas6/Axl signaling attenuates alveolar inflammation in ischemia-reperfusion-induced acute lung injury by up-regulating SOCS3-mediated pathway

Socs3 Expression sentence examples within Downregulated Socs3 Expression



Macrophage p47phox Regulates Pressure Overload-Induced Left Ventricular Remodelling by Modulating IL-4/STAT6/PPARγ Signaling.


The Combination Therapy of Fluorouracil and Oxaliplatin Suppress the Progression of Colon Cancer Through miR-183-5p/SOCS3 Axis and Downregulating PD-L1

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Identification of Novel Transcriptome Signature as a Potential Prognostic Biomarker for Anti-Angiogenic Therapy in Glioblastoma Multiforme


BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition

Socs3 Expression sentence examples within socs3 expression compared



Macrophage p47phox Regulates Pressure Overload-Induced Left Ventricular Remodelling by Modulating IL-4/STAT6/PPARγ Signaling.


Increased PARylation impacts the DNA methylation process in type 2 diabetes mellitus


PRMT2 promotes dextran sulfate sodium-induced colitis by inhibiting SOCS3 via histone H3R8 asymmetric dimethylation.



LINC00893 Inhibits The Progression of Prostate Cancer Through miR-3173-5p/SOCS3/JAK2/STAT3 Pathway



STAT3 and IL-6 Contribute to Corticosteroid Resistance in an OVA and Ozone-induced Asthma Model with Neutrophil Infiltration



Increased IL-6 receptor expression and signaling in ageing cartilage can be explained by loss of TGF-β-mediated IL-6 receptor suppression.


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10.1136/ANNRHEUMDIS-2021-EULAR.448

AB0250 TOFACITINIB SUPPRESSES SEVERAL JAK-STAT PATHWAYS IN RHEUMATOID ARTHRITIS AND BASELINE SIGNALING PROFILE ASSOCIATES WITH TREATMENT RESPONSE



Chemical Chaperone PBA Attenuates ER Stress and Upregulates SOCS3 Expression as a Regulator of Leptin Signaling.



Tofacitinib Suppresses Several JAK-STAT Pathways in Rheumatoid Arthritis In Vivo and Baseline Signaling Profile Associates With Treatment Response



SOCS3 Expression by Thymic Stromal Cells Is Required for Normal T Cell Development


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10.1136/ANNRHEUMDIS-2021-EULAR.1859

POS1198 THE ROLE OF SOCS3 IN COLCHICINE ANTI-INFLAMMATORY EFFECT ON COVID-19 INFECTION



Effects of Selenium-enriched probiotics on ochratoxin A-induced kidney injury and DNMTs expressions in piglets.



Inhibition of miR-483-5p improves the proliferation, invasion and inflammatory response of triple-negative breast cancer cells by targeting SOCS3



SOCS3 Promotes ALV-J Virus Replication via Inhibiting JAK2/STAT3 Phosphorylation During Infection



Research progress on the molecular mechanisms of hepatic metastasis in lung cancer: a narrative review.



Vagal-α7nAChR signaling is required for lung anti-inflammatory responses and arginase 1 expression during an influenza infection.



Sox2 controls neural stem cell self‐renewal through a Fos‐centered gene regulatory network



Resveratrol decreases CD45+CD206− subtype macrophages in LPS‐induced murine acute lung injury by SOCS3 signalling pathway



Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis



Lidocaine Potentiates SOCS3 to Attenuate Inflammation in Microglia and Suppress Neuropathic Pain



Expression of suppressor of cytokine signaling 3 (SOCS3) and interleukin-6 (-174-G/C) polymorphism in atopic conditions



Protective effect of resveratrol on obesity-related osteoarthritis via alleviating JAK2/STAT3 signaling pathway is independent of SOCS3.



Human microRNA‐30 inhibits influenza virus infection by suppressing the expression of SOCS1, SOCS3, and NEDD4



Deletion of suppressor of cytokine signaling 3 (SOCS3) in muscle stem cells does not alter muscle regeneration in mice after injury


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10.12122/j.issn.1673-4254.2019.01.07

[Role of cytokine signal suppressor 3 in the regulatory mechanism of colon cancer invasion and proliferation].



In vivo and in vitro effects of microRNA-221 on hepatocellular carcinoma development and progression through the JAK-STAT3 signaling pathway by targeting SOCS3.



Expression and prognostic value of HER-2/neu, STAT3 and SOCS3 in hepatocellular carcinoma.



IL-10/STAT3/SOCS3 Axis Is Involved in the Anti-inflammatory Effect of Benznidazole



m6A methylation controls pluripotency of porcine induced pluripotent stem cells by targeting SOCS3/JAK2/STAT3 pathway in a YTHDF1/YTHDF2-orchestrated manner



The Mycobacterium tuberculosis glycoprotein Rv1016c protein inhibits dendritic cell maturation, and impairs Th1 /Th17 responses during mycobacteria infection



Promoter methylation and expression of SOCS3 affect the clinical outcome of pediatric acute lymphoblastic leukemia by JAK/STAT pathway.



Cilostazol add-on therapy for celecoxib synergistically inhibits proinflammatory cytokines by activating IL-10 and SOCS3 in the synovial fibroblasts of patients with rheumatoid arthritis



Maternal high-fat diet consumption and chronic hyperandrogenemia are associated with placental dysfunction in female rhesus macaques.



Upregulated expression of STAT3/IL-17 in patients with systemic lupus erythematosus



271 Differential expression of SOCS3 gene and its putative role in the pathogenesis of epithelial ovarian cancer



Constitutive STAT3 phosphorylation and IL-6/IL-10 co-expression are associated with impaired T-cell function in tuberculosis patients.


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