Regulating Cyclin Dependent 사이클린 의존성 조절

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10.7150/jca.63147

In vitro studies, decreased P4HA1 significantly inhibits proliferation and cell cycle, by regulating cyclin-dependent kinases (CDKs), cyclins and CDK inhibitor (CKI).

시험관 내 연구에서 감소된 P4HA1은 사이클린 의존성 키나제(CDK), 사이클린 및 CDK 억제제(CKI)를 조절함으로써 증식과 세포 주기를 상당히 억제합니다.

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10.18632/aging.203303

Silencing circSP3 inhibited HCC cell proliferation and migration by downregulating cyclin-dependent kinase 4, whereas inhibiting miR-198 reversed those effects.

circSP3를 억제하면 사이클린 의존성 키나아제 4를 하향 조절하여 HCC 세포 증식 및 이동을 억제한 반면 miR-198을 억제하면 이러한 효과가 역전되었습니다.

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10.18632/aging.103711

Taken altogether, our results showed that circ_0000326 exerted oncogenic effects on cervical cancer by upregulating Cyclin-dependent kinase 4 via sponging microRNA-338-3p.

종합하면, 우리의 결과는 circ_0000326이 스폰지 microRNA-338-3p를 통해 Cyclin-dependent kinase 4를 상향 조절함으로써 자궁 경부암에 발암 효과를 발휘했음을 보여주었습니다.

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Regulating Cyclin Dependent 사이클린 의존성 조절

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Feb 03, 2023

Regulating Cyclin Dependent(사이클린 의존성 조절)란 무엇입니까?

Regulating Cyclin Dependent 사이클린 의존성 조절 - In vitro studies, decreased P4HA1 significantly inhibits proliferation and cell cycle, by regulating cyclin-dependent kinases (CDKs), cyclins and CDK inhibitor (CKI). ^[1] Silencing circSP3 inhibited HCC cell proliferation and migration by downregulating cyclin-dependent kinase 4, whereas inhibiting miR-198 reversed those effects. ^[2] Taken altogether, our results showed that circ_0000326 exerted oncogenic effects on cervical cancer by upregulating Cyclin-dependent kinase 4 via sponging microRNA-338-3p. ^[3]
시험관 내 연구에서 감소된 P4HA1은 사이클린 의존성 키나제(CDK), 사이클린 및 CDK 억제제(CKI)를 조절함으로써 증식과 세포 주기를 상당히 억제합니다. ^[1] circSP3를 억제하면 사이클린 의존성 키나아제 4를 하향 조절하여 HCC 세포 증식 및 이동을 억제한 반면 miR-198을 억제하면 이러한 효과가 역전되었습니다. ^[2] 종합하면, 우리의 결과는 circ_0000326이 스폰지 microRNA-338-3p를 통해 Cyclin-dependent kinase 4를 상향 조절함으로써 자궁 경부암에 발암 효과를 발휘했음을 보여주었습니다. ^[3]