Melatonin Alleviates 멜라토닌 완화

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10.1093/biolre/ioab084

Summary sentence DON exposure results in human granulosa cells apoptosis and melatonin alleviates the apoptosis by suppressing FOXO1 and ER stress.

요약 문장 DON 노출은 인간 과립막 세포 사멸을 초래하고 멜라토닌은 FOXO1 및 ER 스트레스를 억제하여 세포 사멸을 완화합니다.

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10.1002/med.21582

In addition, extensive experimental data shows that this chronobiotic agent exerts oncostatic effects throughout all stages of tumor growth, from initial cell transformation to mitigation of malignant progression and metastasis; additionally, melatonin alleviates the side effects and improves the welfare of radio/chemotherapy‐treated patients.

또한, 광범위한 실험 데이터는 이 크로노바이오틱 제제가 초기 세포 변형에서 악성 진행 및 전이의 완화에 이르기까지 종양 성장의 모든 단계에 걸쳐 종양 억제 효과를 발휘한다는 것을 보여줍니다. 또한 멜라토닌은 부작용을 완화하고 방사선/화학 요법 치료를 받은 환자의 복지를 향상시킵니다.

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10.1111/jpi.12577

At the same time, they highlight that melatonin alleviates the effects of DEHP as with other endocrine‐disrupting compounds on the ovary.

동시에, 그들은 멜라토닌이 다른 내분비 교란 화합물과 마찬가지로 난소에 대한 DEHP의 영향을 완화한다는 점을 강조합니다.

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Melatonin Alleviates 멜라토닌 완화

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Dec 05, 2024

Melatonin Alleviates(멜라토닌 완화)란 무엇입니까?

Melatonin Alleviates 멜라토닌 완화 - Summary sentence DON exposure results in human granulosa cells apoptosis and melatonin alleviates the apoptosis by suppressing FOXO1 and ER stress. ^[1] In addition, extensive experimental data shows that this chronobiotic agent exerts oncostatic effects throughout all stages of tumor growth, from initial cell transformation to mitigation of malignant progression and metastasis; additionally, melatonin alleviates the side effects and improves the welfare of radio/chemotherapy‐treated patients. ^[2] At the same time, they highlight that melatonin alleviates the effects of DEHP as with other endocrine‐disrupting compounds on the ovary. ^[3]
요약 문장 DON 노출은 인간 과립막 세포 사멸을 초래하고 멜라토닌은 FOXO1 및 ER 스트레스를 억제하여 세포 사멸을 완화합니다. ^[1] 또한, 광범위한 실험 데이터는 이 크로노바이오틱 제제가 초기 세포 변형에서 악성 진행 및 전이의 완화에 이르기까지 종양 성장의 모든 단계에 걸쳐 종양 억제 효과를 발휘한다는 것을 보여줍니다. 또한 멜라토닌은 부작용을 완화하고 방사선/화학 요법 치료를 받은 환자의 복지를 향상시킵니다. ^[2] 동시에, 그들은 멜라토닌이 다른 내분비 교란 화합물과 마찬가지로 난소에 대한 DEHP의 영향을 완화한다는 점을 강조합니다. ^[3]