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Maternal Interleukin-6 Hampers Hippocampal Neurogenesis in Adult Rat Offspring in a Sex-Dependent Manner


Effects of test experience, closed-arm wall color, and illumination level on behavior and plasma corticosterone response in an elevated plus maze in male C57BL/6J mice: a challenge against conventional interpretation of the test

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Activation of 6–8-week-old new mature adult-born dentate granule cells contributes to anxiety-like behavior


Infiltrated regulatory T cells and Th2 cells in the brain contribute to attenuation of sepsis-associated encephalopathy and alleviation of mental impairments in mice with polymicrobial sepsis

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Agomelatine attenuates alcohol craving and withdrawal symptoms by modulating the Notch1 signaling pathway in rats.


Intranasal Neuropeptide Y as a Potential Therapeutic for Depressive Behavior in the Rodent Single Prolonged Stress Model in Females



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Neuroprotective effects of curcumin-loaded nanophytosome on ketamine-induced schizophrenia-like behaviors and oxidative damage in male mice


Postnatal exposure to fluoxetine lead to cognitive-emotional alterations and decreased parvalbumin positive neurons in the hippocampus of juvenile Wistar rats.

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Effects of N-Methyl-D-aspartate receptor (NMDAR) and Ca2+/calmodulin-dependent protein kinase IIα (CaMKIIα) on learning and memory impairment in depressed rats with different charge by modified electroconvulsive shock.


Diurnal rhythm disruptions induced by chronic unpredictable stress relate to depression-like behaviors in rats

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Gender, Depression and Zincum metallicum


[Effects of Bupleurum chinense on the diversity of intestinal flora in depressed mice].

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Reproducible induction of depressive-like behavior in C57BL/6J mice exposed to chronic social defeat stress with a modified sensory contact protocol.


The laterodorsal tegmentum-ventral tegmental area circuit controls depression-like behaviors by activating ErbB4 in DA neurons

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Telmisartan prevents high-fat diet-induced neurovascular impairments and reduces anxiety-like behavior


High-caloric or isocaloric maternal high-fat diets differently affect young-adult offspring behavior in anxiety-related tests and offspring sensitivity to acute fluoxetine

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Rifaximin-Mediated Gut Microbiota Regulation Modulates the Polarization of Microglia During CUMS in Rat


Antidepressant-like Effect of 3-n-Butylphthalide in Rats Exposed to Chronic Unpredictable Mild Stress: Modulation of Brain-Derived Neurotrophic Factor Level and mTOR Activation in Cortex.

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The Cannabinoid Receptor 1 Reverse Agonist AM251 Ameliorates Radiation-Induced Cognitive Decrements


Repetitive Mild Traumatic Brain Injury in a Perinatal Nicotine Exposure Mouse Model of Attention Deficit Hyperactivity Disorder

Like Behavior sentence examples within medial prefrontal cortex



Prefrontal dopamine D1 receptor manipulation influences anxiety behavior and induces neuroinflammation within the hippocampus


FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors

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5-HT7 receptor activation rescues impaired synaptic plasticity in an autistic-like rat model induced by prenatal VPA exposure


Medial prefrontal area reductions, altered expressions of cholecystokinin, parvalbumin, and activating transcription factor 4 in the corticolimbic system, and altered emotional behavior in a progressive rat model of type 2 diabetes

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Developmental toxicity of bisphenol S in Caenorhabditis elegans and NODEF mice.


Sex-specific transgenerational effects of adolescent morphine exposure on short-term memory and anxiety behavior: Male linage

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Resveratrol ameliorates physical and psychological stress-induced depressive-like behavior


Decidual cell FKBP51–progesterone receptor binding mediates maternal stress–induced preterm birth

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Prenatal alcohol-induced sex differences in immune, metabolic and neurobehavioral outcomes in adult rats


Sex Differences in Behavioral and Brainstem Transcriptomic Neuroadaptations following Neonatal Opioid Exposure in Outbred Mice

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PTEN in prefrontal cortex is essential in regulating depression-like behaviors in mice


CD36 deficiency affects depressive-like behaviors possibly by modifying gut microbiota and the inflammasome pathway in mice

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Natural Dietary Supplement, Carvacrol, Alleviates LPS-Induced Oxidative Stress, Neurodegeneration, and Depressive-Like Behaviors via the Nrf2/HO-1 Pathway


Rapamycin, but not minocycline, significantly alters ultrasonic vocalization behavior in C57BL/6J pups in a flurothyl seizure model

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Combined effects of royal jelly and environmental enrichment against stress-induced cognitive and behavioral alterations in male rats: behavioral and molecular studies.


A model of negative emotional contagion between male-female rat dyads: Effects of voluntary exercise on stress-induced behavior and BDNF-TrkB signaling

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Investigation of the relationship between chronic montelukast treatment, asthma and depression-like behavior in mice


Sodium phenylbutyrate reduces repetitive self-grooming behavior and rescues social and cognitive deficits in mouse models of autism.

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A two-hit adversity model in developing rats reveals sex-specific impacts on prefrontal cortex structure and behavior


Modulation of relapse-like drinking in male Sprague-Dawley rats by ligands targeting the α5GABAA receptor

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Anhedonic- and anxiogenic-like behaviors and neurochemical alterations are abolished by a single administration of a selenium-containing compound in chronically stressed mice


Curcumin Ameliorates Chronic Mild Stress-Induced Depressive-Like Behavior via HMGB1/TLR4/NF-κB Signaling Pathway

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Magnetic properties and spin glass behavior in an antiferromagnet KFeO2


Heterostructure Fe2O3–In2O3 Nanoparticles as Hydrogen Gas Sensor

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CB1 receptor neutral antagonist treatment epigenetically increases neuropeptide Y expression and decreases alcohol drinking


Gut microbiome partially mediates and coordinates the effects of genetics on anxiety-like behavior in Collaborative Cross mice

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Short-term high-fat diet induces cognitive decline, aggression, and anxiety-like behavior in adult zebrafish


Baicalein 5,6-Dimethyl Ether Prevents Memory Deficits in the Scopolamine Zebrafish Model by Regulating Cholinergic and Antioxidant Systems

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Inflammation plays a causal role in fatigue-like behavior induced by pelvic irradiation in mice


Difference in the brain serotonin and its metabolite level and anxiety-like behavior between forced and voluntary exercise conditions in rats

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GABAB receptor/HCN channel complexes in VTA dopamine neurons limit synaptic inhibition and prevent anxiety-like behavior


VTA-projecting cerebellar neurons mediate stress-dependent depression-like behavior

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Rodent models for nicotine withdrawal


Treatment with Autophagy Inducer Trehalose Alleviates Memory and Behavioral Impairments and Neuroinflammatory Brain Processes in db/db Mice

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Maternal crack cocaine use in rats leads to depressive- and anxiety-like behavior, memory impairment, and increased seizure susceptibility in the offspring


Effects of Tyrosine and Tryptophan in Rats with Diet-Induced Obesity

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Pulsed Radiofrequency Upregulates Serotonin Transporters and Alleviates Neuropathic Pain-Induced Depression in a Spared Nerve Injury Rat Model


Dynamic Change of Endocannabinoid Signaling in the Medial Prefrontal Cortex Controls the Development of Depression After Neuropathic Pain

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Effects of a 33-sequential beam galactic cosmic ray analog on male mouse behavior and evaluation of CDDO-EA as a radiation countermeasure


Neurons expressing mu opioid receptors of the habenula promote negative affect in a projection-specific manner

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Effects of nicotinic acetylcholine receptor-activating alkaloids on anxiety-like behavior in zebrafish


Assessment of Neurotoxicity Following Single and Co-exposure of Cadmium and Mercury in Adult Zebrafish: Behavior Alterations, Oxidative Stress, Gene Expression, and Histological Impairment in Brain

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Imbalanced post- and extrasynaptic SHANK2A functions during development affect social behavior in SHANK2-mediated neuropsychiatric disorders


Social Deficits and Repetitive Behaviors Are Improved by Early Postnatal Low-Dose VPA Intervention in a Novel shank3-Deficient Zebrafish Model

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Automated home-cage for the evaluation of innate non-reflexive pain behaviors in a mouse model of inflammatory pain


Maternal separation alters the reward system of activity-based anorexia rats

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Exposure to Vicarious Social Defeat Stress and Western-Style Diets During Adolescence Leads to Physiological Dysregulation, Decreases in Reward Sensitivity, and Reduced Antidepressant Efficacy in Adulthood


GABRB2, a key player in neuropsychiatric disorders and beyond.

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Downregulated SIRT1 in the CeA is involved in chronic pain-depression comorbidity


GPR151 in nociceptors modulates neuropathic pain via regulating P2X3 function and microglial activation.

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Rheological and Thermal Properties of Levan From Bacillus Mojavensis


Rheological and Thermal Properties of Levan from Bacillus mojavensis

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Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain


Effects of Gastrodin on Analgesia and Inhibition of Ferroptosis

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Osthole Ameliorates Estrogen Deficiency-Induced Cognitive Impairment in Female Mice


DW2009 Elevates the Efficacy of Donepezil against Cognitive Impairment in Mice

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Decynium-22 affects behavior in the zebrafish light/dark test


Decynium-22 affects behavior in the zebrafish light/dark test

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Stress-induced alterations of mesocortical and mesolimbic dopaminergic pathways


Stress-induced alterations of mesocortical and mesolimbic dopaminergic pathways

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FTY720 (Fingolimod), a modulator of sphingosine-1-phosphate receptors, increases baseline hypothalamic-pituitary adrenal axis activity and alters behaviors relevant to affect and anxiety


Excitatory neuronal CHD8 in the regulation of neocortical development and sensory-motor behaviors.

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P.230 Effects of online behavioural activation on depression during covid-19


The dual orexin receptor antagonist almorexant blocks the sleep-disrupting and daytime stimulant effects of methamphetamine in rhesus monkeys.

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Environmental enrichment modulates HPA axis reprogramming in adult male rats exposed to early adolescent stress


A comparative analysis of kainate receptor GluK2 and GluK5 knockout mice in a pure genetic background

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Genomic Modules and Intramodular Network Convergency of Susceptibility and Resilience in Multimodeled Stress in Male Mice


Pediococcus acidilactici CCFM6432 mitigates chronic stress-induced anxiety and gut microbial abnormalities.

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Gadd45b is a novel mediator of depression-like behaviors and neuroinflammation after cerebral ischemia.


Minocycline inhibits sleep deprivation-induced aberrant microglial activation and Keap1-Nrf2 expression in mouse hippocampus

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Investigating the role of 5-HT2A and 5-HT2C receptor activation in the effects of psilocybin, DOI, and citalopram on marble burying in mice


Early-adolescent antibiotic exposure results in mitochondrial and behavioral deficits in adult male mice

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Medial septum tau accumulation induces spatial memory deficit via disrupting medial septum–hippocampus cholinergic pathway


Endogenous ω-3 fatty acids in Fat-1 mice attenuated depression-like behaviors, spatial memory impairment and relevant changes induced by olfactory bulbectomy.

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Activation of Alpha7 Nicotinic Acetylcholine Receptors Reduce Chronic Pain-Induced Depression-Like Behaviors Via WNT/β-Catenin Pathway


(E)-3-furan-2-yl-N-phenylacrylamide (PAM-4) decreases nociception and emotional manifestations of neuropathic pain in mice by α7 nicotinic acetylcholine receptor potentiation.

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The antidepressant‐like effects of Shen Yuan: Dependence on hippocampal BDNF–TrkB signaling activation in chronic social defeat depression‐like mice


Involvement of the dopamine system in the effect of chronic social isolation during adolescence on social behaviors in male C57 mice

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Young Plasma Induces Antidepressant-Like Effects in Aged Rats Subjected to Chronic Mild Stress by Suppressing Indoleamine 2,3-Dioxygenase Enzyme and Kynurenine Pathway in the Prefrontal Cortex.


Quercetin alleviates chronic unpredictable mild stress-induced depressive-like behaviors by promoting adult hippocampal neurogenesis via FoxG1/CREB/ BDNF signaling pathway