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Kinase 3 sentence examples within internal tandem duplication



Discovery of novel 4-azaaryl-N-phenylpyrimidin-2-amine derivatives as potent and selective FLT3 inhibitors for acute myeloid leukaemia with FLT3 mutations.


FLT3 Gene Mutation in Acute Myeloid Leukemia: Correlation with Hematological, Immunophenotypic, and Cytogenetic Characteristics

Kinase 3 sentence examples within receptor interacting protein



Transplantation of olfactory ensheathing cells promotes the therapeutic effect of neural stem cells on spinal cord injury by inhibiting necrioptosis


IL-18 maintains the homeostasis of mucosal immune system via inflammasome-independent but microbiota-dependent manner

Kinase 3 sentence examples within mitogen activated protein



Network pharmacology integrated molecular docking reveals the bioactive components and potential targets of Morinda officinalis–Lycium barbarum coupled-herbs against oligoasthenozoospermia


Medical Significance of Uterine Corpus Endometrial Carcinoma Patients Infected With SARS-CoV-2 and Pharmacological Characteristics of Plumbagin



Kinase 3 sentence examples within serine threonine kinase



Dysregulation of GSK3β-Target Proteins in Skin Fibroblasts of Myotonic Dystrophy Type 1 (DM1) Patients.


Recent Advances in the Discovery of GSK-3 Inhibitors from Synthetic Origin in the Treatment of Neurological Disorders.

Kinase 3 sentence examples within receptor interacting serine



Selenomethionine alleviates LPS-induced JNK/NLRP3 inflammasome-dependent necroptosis by modulating miR-15a and oxidative stress in chicken lungs.


A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin2α-induced corpus luteum regression

Kinase 3 sentence examples within homeodomain interacting protein



Emerging landscape of circHIPK3 and its role in cancer and other diseases


Circ-HIPK3 regulates YAP1 expression by sponging miR-381-3p to promote oral squamous cell carcinoma development

Kinase 3 sentence examples within eukaryotic translation initiation



Dihydroartemisinin triggers ferroptosis in primary liver cancer cells by promoting and unfolded protein response-induced upregulation of CHAC1 expression


Targeting UPR branches, a potential strategy for enhancing efficacy of cancer chemotherapy.

Kinase 3 sentence examples within approximately 30 %



FLT3 mutated acute myeloid leukemia: 2021 treatment algorithm


FLT3-TKD in the Prognosis of Patients With Acute Myeloid Leukemia: A Meta-Analysis

Kinase 3 sentence examples within phosphatidylinositol 3 kinase



Inhibiting PI3K leads to glucose metabolism disturbance in default mode network


Vitronectin regulates the axon specification of mouse cerebellar granule cell precursors via αvβ5 integrin in the differentiation stage

Kinase 3 sentence examples within extracellular signal regulated



Activation of Galanin Receptor 1 with M617 Attenuates Neuronal Apoptosis via ERK/GSK-3β/TIP60 Pathway After Subarachnoid Hemorrhage in Rats.


Lithium chloride inhibits the migration and invasion of osteosarcoma cells by blocking nuclear translocation of phospho-Erk.

Kinase 3 sentence examples within activated protein kinase



Novel and emerging therapeutic drug targets for management of type 2 Diabetes Mellitus


TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy.

Kinase 3 sentence examples within serine threonine protein



The role of sonic hedgehog homologue signal pathway in hypospadias aetiology.


TAM-derived extracellular vesicles containing microRNA-29a-3p explain the deterioration of ovarian cancer

Kinase 3 sentence examples within neurotrophic receptor tyrosine



Role of novel cancer gene SLITRK3 to activate NTRK3 in squamous cell lung cancer


The Rotary Cell Culture System increases NTRK3 expression and promotes neuronal differentiation and migratory ability of neural stem cells cultured on collagen sponge

Kinase 3 sentence examples within tumor necrosis factor



[Research progress of necroptosis on bone related diseases].


Exploration of Anti-Staphylococcus Aureus Activity and Molecular Mechanism of Wuweixiaoduyin using Network Pharmacology Anti-Staphylococcus Aureus Activity of Wuweixiaoduyin using Network Pharmacology

Kinase 3 sentence examples within mixed lineage kinase



Tumor necroptosis is correlated with a favorable immune cell signature and programmed death-ligand 1 expression in cholangiocarcinoma


CAMK2/CaMKII activates MLKL in short-term starvation to facilitate autophagic flux.

Kinase 3 sentence examples within phosphoinositide 3 kinase



20(S)-Panaxadiol Enhances Hemostatic Effect on Activated Platelet by Affecting Calcium Signaling


Histone deacetylase inhibitor induced pVHL-independent degradation of HIF-1α and hierarchical quality control of pVHL via chaperone system

Kinase 3 sentence examples within nuclear factor kappa



Exosomal miR-193b-5p as a regulator of LPS-induced inflammation in dairy cow mammary epithelial cells.


Long-term effect of hematopoietic cell transplantation on systemic inflammation in patients with mucopolysaccharidoses.

Kinase 3 sentence examples within death associated protein



Network analysis identifies DAPK3 as a potential biomarker for lymphatic invasion and colon adenocarcinoma prognosis


VIRMA contributes to non-small cell lung cancer progression via N6-methyladenosine-dependent DAPK3 post-transcriptional modification.

Kinase 3 sentence examples within phosphorylated glycogen synthase



Effects of the decrease of β-catenin expression on human vaginal fibroblasts of women with pelvic organ prolapse.


Hypoglycemic and hypolipidemic effects of total glycosides of Cistanche tubulosa in diet/streptozotocin-induced diabetic rats.

Kinase 3 sentence examples within insulin receptor substrate



Fruits of Rosa laevigata and its bio-active principal sitostenone facilitate glucose uptake and insulin sensitivity in hepatic cells via AMPK/PPAR-γ activation


Effects of Physiological Doses of Resveratrol and Quercetin on Glucose Metabolism in Primary Myotubes

Kinase 3 sentence examples within activating transcription factor



Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity.


WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism.

Kinase 3 sentence examples within hematopoietic growth factor



GS-3583, a novel FLT3 agonist Fc fusion protein, to expand conventional dendritic cells in healthy volunteers.


Phase 1b dose escalation study to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of GS-3583, a FLT3 agonist Fc fusion protein, in patients with advanced solid tumors.

Kinase 3 sentence examples within receptor tyrosine kinase



Abstract 3039: Pediatric preclinical testing consortium evaluation of the dual SYK/FLT3 inhibitor TAK-659 in xenograft models of pediatric acute lymphoblastic leukemia


Anti-leukemic Activity of AIU2008 in FLT3-ITD-positive Acute Myeloid Leukemia

Kinase 3 sentence examples within conserved serine threonine



GSK3s: nodes of multilayer regulation of plant development and stress responses.


GSK3β as a novel promising target to overcome chemoresistance in pancreatic cancer.

Kinase 3 sentence examples within stem cell factor



In Vitro Expansion of Fetal Liver Hematopoietic Stem Cells


In vitro expansion of fetal liver hematopoietic stem cells

Kinase 3 sentence examples within motif chemokine ligand



Characterisation of the serum cytokine profile in feline atopic skin syndrome.


Stromal cells in the tumor microenvironment promote the progression of oral squamous cell carcinoma

Kinase 3 sentence examples within refractory acute myeloid



Acute cardiotoxicity after initiation of the novel tyrosine kinase inhibitor gilteritinib for acute myeloid leukemia


Personalized patient care with aggressive hematological malignancies in non-responders to first-line treatment

Kinase 3 sentence examples within quantitative real time



Knockdown of Circ_SLC39A8 protects against the progression of osteoarthritis by regulating miR-591/IRAK3 axis


Circ_0016760 accelerates non-small-cell lung cancer progression through miR-646/AKT3 signaling in vivo and in vitro.

Kinase 3 sentence examples within p38 mitogen activated



MTA2 silencing attenuates the metastatic potential of cervical cancer cells by inhibiting AP1-mediated MMP12 expression via the ASK1/MEK3/p38/YB1 axis


Selenoproteins Protect Against Avian Liver Necrosis by Metabolizing Peroxides and Regulating Receptor Interacting Serine Threonine Kinase 1/Receptor Interacting Serine Threonine Kinase 3/Mixed Lineage Kinase Domain-Like and Mitogen-Activated Protein Kinase Signaling

Kinase 3 sentence examples within viral oncogene homolog



Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor


Betulin, a Newly Characterized Compound in Acacia Auriculiformis Bark, is a Multi-target Protein Kinase Inhibitor

Kinase 3 sentence examples within transient receptor potential



A dysfunctional TRPV4-GSK3β pathway prevents osteoarthritic chondrocytes from sensing changes in extracellular matrix viscoelasticity.


Pharmacological enhancement of KCC2 gene expression exerts therapeutic effects on human Rett syndrome neurons and Mecp2 mutant mice

Kinase 3 sentence examples within cyclin dependent kinase



Neuroprotective Studies of Evodiamine in an Okadaic Acid-Induced Neurotoxicity


Odontogenic gene expression profile of human dental pulp-derived cells under high glucose influence: a microarray analysis

Kinase 3 sentence examples within kinase receptor interacting



Reconstitution of Human Necrosome Interactions in Saccharomyces cerevisiae


A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation.

Kinase 3 sentence examples within peroxisome proliferator activated



Studi Biokemoinformatika Kandungan Kimia Daun Sambiloto (Andrographis paniculata (Burm.f.) Nees) sebagai Antihiperglikemia serta Prediksi Parameter Farmakokinetik dan Toksisitas


Systematic analysis of the potential off-target activities of osimertinib by computational target fishing.

Kinase 3 sentence examples within nuclear factor erythroid



Emodin Prevented Depression in Chronic Unpredicted Mild Stress Exposured Rats by Targeting MiR139-5p/5-Lipoxygenase


Emodin Prevented Depression in Chronic Unpredicted Mild Stress-Exposed Rats by Targeting miR-139-5p/5-Lipoxygenase

Kinase 3 sentence examples within mutant acute myeloid



Abstract 1096: FMS-like tyrosine kinase 3 (FLT3) inhibition by olverembatinib (HQP1351) downregulates MCL-1 and synergizes with BCL-2 inhibitor APG-2575 in preclinical models of FLT3-mutant acute myeloid leukemia (AML)


Homoharringtonine Synergized with Gilteritinib Results in the Downregulation of Myeloid Cell Leukemia-1 by Upregulating UBE2L6 in FLT3-ITD-Mutant Acute Myeloid (Leukemia) Cell Lines

Kinase 3 sentence examples within macrophage colony stimulating



A sensitive and rapid chemiluminescence immunoassay for point-of-care testing (POCT) of copeptin in serum based on high-affinity monoclonal antibodies via cytokine-assisted immunization

Kinase 3 sentence examples within vascular endothelial growth



Berberine associated photodynamic therapy promotes autophagy and apoptosis via ROS generation in renal carcinoma cells.

Kinase 3 sentence examples within colony stimulating factor



Modeling the Hematopoietic Landscape

Kinase 3 sentence examples within tyrosine protein kinase



A network-based analysis and experimental validation of traditional Chinese medicine Yuanhu Zhitong Formula in treating neuropathic pain.

Kinase 3 sentence examples within real time polymerase



Platelet Rich Plasma Regulates Wnt/Beta-Catenin Signal Pathway in Rabbit Chondrocytes by Mediating Interleukin 1 Beta

Kinase 3 sentence examples within platelet derived growth



Key Common Genes in Obstructive Sleep Apnea and Lung Cancer are Associated with Prognosis of Lung Cancer Patients

Kinase 3 sentence examples within unfolded protein response



Vitamin K2 Modulates Organelle Damage and Tauopathy Induced by Streptozotocin and Menadione in SH-SY5Y Cells

Kinase 3 sentence examples within damage inducible transcript



How autophagy controls the intestinal epithelial barrier.

Kinase 3 sentence examples within protein phosphatase 1



Long-term depression-related tau phosphorylation is enhanced by methylene blue in healthy rat hippocampus.

Kinase 3 sentence examples within binding protein 1



Viral Z-RNA triggers ZBP1-dependent cell death.

Kinase 3 sentence examples within semen armeniacae amarum



The mechanism and active compounds of semen armeniacae amarum treating coronavirus disease 2019 based on network pharmacology and molecular docking

Kinase 3 sentence examples within protein kinase 1



Necroptosis is required for atrial fibrillation and involved in aerobic exercise‐conferred cardioprotection

Kinase 3 sentence examples within epidermal growth factor



Screening safflower injection for constituents with activity against stroke using comprehensive chemical profiling coupled with network pharmacology

Kinase 3 sentence examples within proliferator activated receptor



Drug repositioning for treatment-resistant depression: Hypotheses from a pharmacogenomic study

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Kinase 3 키나제 3
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