Function Analyzer(함수 분석기)란 무엇입니까?
Function Analyzer 함수 분석기 - Standard hematological and coagulation analyses, thromboelastography (TEG), platelet-function analyzer-100 (PFA), several platelet activation parameters (CD62P-CD63, AnnexinV) and growth factors (TGFb1, VEGF, PDGF-AB/BB, EGF, TGFb2, FGF-2, PDGF-AA) analyses were performed. [1]표준 혈액 및 응고 분석, thromboelastography(TEG), platelet-function analyzer-100(PFA), 여러 혈소판 활성화 매개변수(CD62P-CD63, AnnexinV) 및 성장 인자(TGFb1, VEGF, PDGF-AB/BB, EGF, TGFb2, FGF-2, PDGF-AA) 분석을 수행하였다. [1]
light transmission aggregometry 광 투과 집합체
From baseline, the treatment with anti-PCSK9 mAbs: i) in ASA HC patients, significantly decreased platelet aggregation detected in platelet-rich plasma by light transmission aggregometry and in whole blood Platelet Function Analyzer-100 assay; ii) in all HC patients, significantly decreased platelet membrane expression of CD62P and plasma levels of the in vivo platelet activation markers soluble CD40 Ligand, Platelet Factor-4, and soluble P-Selectin. [1] Platelet aggregation was tested with 96-well light transmission aggregometry (LTA), and when an effect ≥20% compared to vehicle was observed, flow cytometric platelet aggregation and activation were evaluated and closure time was measured by Platelet Function Analyzer (PFA-200). [2] All subjects were assessed with platelet function analyzer-100 (PFA-100), epinephrine (Epi) and ADP-induced light transmission aggregometry (LTA), thromboelastometry (ROTEM) and endogenous thrombin potential (ETP). [3]기준선에서, 항-PCSK9 mAb를 사용한 치료: i) ASA HC 환자에서, 광 투과 응집법 및 전혈 혈소판 기능 분석기-100 분석에 의해 혈소판이 풍부한 혈장에서 검출된 혈소판 응집을 유의하게 감소시켰고; ii) 모든 HC 환자에서 CD62P의 혈소판 막 발현 및 생체내 혈소판 활성화 마커 가용성 CD40 리간드, 혈소판 인자-4 및 가용성 P-셀렉틴의 혈장 수준이 유의하게 감소했습니다. [1] 혈소판 응집은 96-well 광투과응집법(LTA)으로 시험하였으며, 비히클 대비 ≥20% 효과가 관찰되면 유세포분석 혈소판 응집 및 활성화를 평가하고 혈소판 기능 분석기(PFA-200)로 폐쇄 시간을 측정하였다. . [2] nan [3]
Platelet Function Analyzer 혈소판 기능 분석기
Nowadays point of care (POC) management of coagulopathy and bleeding is available using methods such as thromboelastometry (ROTEM), platelet function analyzer (PFA 200) and agregometer (Multiplate) which contribute to the optimalization of blood products and coagulation factors administration. [1] The Platelet Function Analyzer Closure Times (PFA-CT) are strongly prolonged in VWD 2A, 2B and 2M. [2] L’emostasi primaria, la coagulazione e la fibrinolisi possono essere esplorate con test globali (Platelet Function Analyzer [PFA], TP, TCA, tempo di lisi) o con test piu specifici (dosaggio dei fattori). [3] Platelet function testing was performed on platelet function analyzer (PFA-200) that ‘in vitro’ simulates the process of aggregation and platelet activation. [4] Interestingly, the closure time with adenosine diphosphate, assessed using the Platelet Function Analyzer 100 (Siemens Healthcare Diagnostics, Los Angeles, CA), measured after each important step of this complex procedure, correlated very well with the severity of the paravalvular leak. [5] 5 µM ADP; platelet function analyzer (PFA)-100™–collagen and ADP (CADP) and collagen and epinephrine (CEPI); VerifyNow™–ASA; and urinary 11-dehydro-thromboxane B2 (TxB2) and serum TxB2. [6] To evaluate the clotting ability of the blood and thus the bleeding tendency, the closure time of the platelet function analyzer (PFA-100®, Dade Behring, Marburg, Germany) was used. [7] In all patients fulfilling the requirements for the German Trauma Society (DGU) Traumaregister® who were admitted directly from the scene of the incident, platelet function was analyzed using the Platelet Function Analyzer (PFA 100®) with adenosine diphosphate (ADP) and epinephrine as activation factors. [8] From baseline, the treatment with anti-PCSK9 mAbs: i) in ASA HC patients, significantly decreased platelet aggregation detected in platelet-rich plasma by light transmission aggregometry and in whole blood Platelet Function Analyzer-100 assay; ii) in all HC patients, significantly decreased platelet membrane expression of CD62P and plasma levels of the in vivo platelet activation markers soluble CD40 Ligand, Platelet Factor-4, and soluble P-Selectin. [9] Platelet aggregation was tested with 96-well light transmission aggregometry (LTA), and when an effect ≥20% compared to vehicle was observed, flow cytometric platelet aggregation and activation were evaluated and closure time was measured by Platelet Function Analyzer (PFA-200). [10] Several whole blood point-of-care platelet function analyzers are available; however, inter-device differences have not been examined systematically. [11] There are several platelet function analyzers available that can be used to assess the effect of antiplatelet drugs and the potential risk for bleeding before surgery. [12] Whole-blood impedance aggregometry (Multiplate) and platelet function analyzer (PFA) may be used as rapid screening tools to exclude PFDs. [13] — To analyze platelet function proficiency testing for Platelet Function Analyzer PFA-100, platelet aggregation, PlateletWorks, and PlateletMapping. [14] We aimed to assess if immuno-affinity purified anti-β2-glycoprotein I (aβ2GPI) antibodies enhance platelet activation inducing a significant flow obstruction in a platelet function analyzer (PFA). [15] Plasmatic coagulation testing, blood counts, plasmatic von Willebrand testing, platelet function analyzer (PFA-100), and impedance aggregometry (MEA) were performed in all children. [16] All subjects were assessed with platelet function analyzer-100 (PFA-100), epinephrine (Epi) and ADP-induced light transmission aggregometry (LTA), thromboelastometry (ROTEM) and endogenous thrombin potential (ETP). [17] We investigated the detection rates of Platelet Function Analyzer (PFA)-100 (Dade Behring AG, Düdingen, Switzerland) for drug-induced platelet dysfunction and analyzed potential contributors to HTPR with practical PFA-100 data over six years. [18] Subsequent studies have further confirmed that platelet function analyzer 100 (PFA) and quantitative VWF multimers are strongly associated with gradients, that they function as biomarkers in demonstrating treatment responses, that bleeding is as prevalent as in aortic stenosis, and that septal reduction therapy can be curative of transfusion-dependent gastrointestinal hemorrhage from angiodysplasia. [19] Measurement of closure time (CT) using the platelet function analyzer-200 (PFA-200) is highly sensitive to the presence of UL VWF multimers in added VWF concentrates. [20] Platelet function was assessed in the first 48 hours and subsequently after 3 months using four methods: VerifyNow™ (VFN), whole blood platelet aggregation (WBPA) with arachidonic acid (AA) and collagen as agonists, and platelet function analyzer (PFA). [21] The platelet function was assessed using the platelet function analyzer (PFA)-200. [22] Bei Patienten, die nach den Kriterien des DGU-Traumaregisters über den Schockraum als Direktzuweisung vom Unfallort aufgenommen wurden, war eine Bestimmung der Thrombozytenfunktion mittels Platelet Function Analyzer (PFA 100®) erfolgt. [23] Standard laboratory tests and an extended evaluation of hemostasis by rotational thromboelastometry, platelet function analyzer (PFA) and multiple electrode aggregometry as well as thrombin generation assays and measurement of fibrinolytic potential were performed in 20 patients on hemodialysis, 10 patients on peritoneal dialysis, 10 patients with chronic kidney disease stage G5 (CKD5) and in 10 healthy controls (HC). [24] The mechanism of this effect is not fully understood, and Quintás-Cardama and coworkers analyzed the impact of TKI therapy on platelet functions via the stimulation of platelet aggregation with adenosine diphosphate, arachidonic acid, epinephrine, collagen, and ristocetin, together with using the platelet function analyzer (PFA-100) in 75 patients with CML-CP. [25] After oral administration of aspirin enteric coated tablets for 7±1 d, the maximum aggregation ratio (MAR) induced by arachidonic acid (AA) was determined by PL-12 Platelet Function Analyzer. [26] Dear Editor, Platelet Function Analyzer (PFA)-100 (Siemens, Erlangen, Germany) has been proposed for preoperative screening because it is simple, easy-to-use, and can evaluate both the adhesion and aggregation of platelets [1]. [27] The platelet function was assessed by a Platelet Function Analyzer-200, in which clopidogrel hyporesponsiveness was defined as a closure time (CT) of ≤ 106 s. [28] Thrombelastography and platelet function analyzer (PFA)-100 guide antiplatelet titration. [29]현재 혈액제제 및 응고인자 투여의 최적화에 기여하는 혈전탄성측정기(ROTEM), 혈소판 기능 분석기(PFA 200) 및 응집계(멀티플레이트)와 같은 방법을 사용하여 응고병증 및 출혈의 현장 진료(POC) 관리가 가능합니다. [1] 혈소판 기능 분석기 폐쇄 시간(PFA-CT)은 VWD 2A, 2B 및 2M에서 강력하게 연장됩니다. [2] nan [3] nan [4] 흥미롭게도, 이 복잡한 절차의 각 중요한 단계 후에 측정한 Platelet Function Analyzer 100(Siemens Healthcare Diagnostics, Los Angeles, CA)을 사용하여 평가한 이인산 아데노신의 폐쇄 시간은 판막주위 누출의 심각성과 매우 밀접한 상관관계가 있었습니다. [5] nan [6] nan [7] nan [8] 기준선에서, 항-PCSK9 mAb를 사용한 치료: i) ASA HC 환자에서, 광 투과 응집법 및 전혈 혈소판 기능 분석기-100 분석에 의해 혈소판이 풍부한 혈장에서 검출된 혈소판 응집을 유의하게 감소시켰고; ii) 모든 HC 환자에서 CD62P의 혈소판 막 발현 및 생체내 혈소판 활성화 마커 가용성 CD40 리간드, 혈소판 인자-4 및 가용성 P-셀렉틴의 혈장 수준이 유의하게 감소했습니다. [9] 혈소판 응집은 96-well 광투과응집법(LTA)으로 시험하였으며, 비히클 대비 ≥20% 효과가 관찰되면 유세포분석 혈소판 응집 및 활성화를 평가하고 혈소판 기능 분석기(PFA-200)로 폐쇄 시간을 측정하였다. . [10] nan [11] nan [12] nan [13] nan [14] nan [15] nan [16] nan [17] nan [18] 후속 연구에서 혈소판 기능 분석기 100(PFA) 및 정량적 VWF 멀티머가 구배와 강력하게 연관되어 있고, 치료 반응을 입증하는 데 바이오마커로 기능하고, 출혈이 대동맥 협착증만큼 만연하고, 중격 감소 요법이 혈관이형성증으로 인한 수혈 의존성 위장관 출혈의 치료제. [19] nan [20] nan [21] nan [22] nan [23] nan [24] nan [25] nan [26] nan [27] nan [28] nan [29]
Wave Function Analyzer 파동 함수 분석기
Meanwhile, an explicit surface analysis on compounds were carried out theoretically using the wave function analyzer (Multiwfn 3. [1] The reactive sites of the molecule were identified and their quantitative values were defined using the electrostatic potential model proposed in the multifunctional wave function analyzer multiwfn. [2]한편, 파동함수분석기(Multiwfn 3.1)를 이용하여 이론적으로 화합물에 대한 명시적 표면분석을 수행하였다. [1] 다기능 파동함수 분석기 multiwfn에서 제안한 정전기 전위 모델을 사용하여 분자의 반응성 부위를 확인하고 정량적 값을 정의했습니다. [2]
Distribution Function Analyzer 분포 함수 분석기
For energetic particles below 40 keV , observations from Cluster CIS/CODIF (Cluster Ion Spectrometry COmposition and DIstribution Function analyzer) are used. [1] For energetic particles below 40 keV, observations from Cluster CIS/CODIF (Cluster Ion Spectrometry COmposition and DIstribution Function analyzer) are used. [2]아래의 에너지 입자의 경우 40 keV, Cluster CIS/CODIF(Cluster Ion Spectrometry COMposition and Distribution Function Analyzer)의 관측치가 사용됩니다. [1] 40keV 미만의 에너지 입자의 경우 클러스터 CIS/CODIF(클러스터 이온 분광계 구성 및 분포 함수 분석기)의 관찰이 사용됩니다. [2]
Cardiac Function Analyzer 심장 기능 분석기
The hemodynamic response was evaluated with a cardiac function analyzer, which measures the left ventricular systolic intervals (preejection and ejection periods) and automatically calculates an index of systolic function and estimates the ejection fraction (Systocor mod IS100). [1] The hemodynamic response was evaluatedwith a cardiac function analyzer, which measures the left ventricular systolic intervals (preejection and ejection periods) andautomatically calculates an index of systolic function and estimates the ejection fraction (Systocor mod IS100). [2]혈역학적 반응은 좌심실 수축기 간격(예측 및 박출 기간)을 측정하고 자동으로 수축기 기능 지수를 계산하고 박출률을 추정하는 심장 기능 분석기로 평가되었습니다(Systocor mod IS100). [1] 혈역학적 반응은 좌심실 수축기 간격(예측 및 박출 기간)을 측정하고 수축기 기능 지수를 자동으로 계산하고 박출률을 추정하는 심장 기능 분석기로 평가되었습니다(Systocor mod IS100). [2]
function analyzer 100 함수 분석기 100
Interestingly, the closure time with adenosine diphosphate, assessed using the Platelet Function Analyzer 100 (Siemens Healthcare Diagnostics, Los Angeles, CA), measured after each important step of this complex procedure, correlated very well with the severity of the paravalvular leak. [1] Subsequent studies have further confirmed that platelet function analyzer 100 (PFA) and quantitative VWF multimers are strongly associated with gradients, that they function as biomarkers in demonstrating treatment responses, that bleeding is as prevalent as in aortic stenosis, and that septal reduction therapy can be curative of transfusion-dependent gastrointestinal hemorrhage from angiodysplasia. [2]흥미롭게도, 이 복잡한 절차의 각 중요한 단계 후에 측정한 Platelet Function Analyzer 100(Siemens Healthcare Diagnostics, Los Angeles, CA)을 사용하여 평가한 이인산 아데노신의 폐쇄 시간은 판막주위 누출의 심각성과 매우 밀접한 상관관계가 있었습니다. [1] 후속 연구에서 혈소판 기능 분석기 100(PFA) 및 정량적 VWF 멀티머가 구배와 강력하게 연관되어 있고, 치료 반응을 입증하는 데 바이오마커로 기능하고, 출혈이 대동맥 협착증만큼 만연하고, 중격 감소 요법이 혈관이형성증으로 인한 수혈 의존성 위장관 출혈의 치료제. [2]