Complement Signaling(보완 신호)란 무엇입니까?
Complement Signaling 보완 신호 - Acquisition of the suppressor phenotype is dependent on several pathways including complement signaling, which can be targeted therapeutically to enhance antitumor immunity. [1] This study investigated the potential changes in complement signaling, and the associated inflammatory mediators, in mild-to-critical COVID-19 patients and their clinical outcomes. [2] Complement signaling is thought to serve as an opsonization signal to promote the phagocytosis of synapses by microglia. [3] Complement signaling on B cells affects germinal center dynamics. [4] Complement signaling is particularly important in directing neuronal responses to tissue injury, neurotrauma, and nerve lesions. [5] These lncRNAs may affect ES prognosis by regulating GSE17721_CTRL_VS_PAM3CSK4_12H_BMDC_UP, GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP, GSE29615_CTRL_VS_DAY3_ LAIV_IFLU_VACCINE_PBMC_UP, complement signaling, interleukin 2-signal transducer and activator of transcription 5 signaling, and protein secretion. [6] Complement signaling through C3aR and C5aR expressed on effector T lymphocytes prevent the production of the cytokine interleukin-10 (IL-10). [7] Furthermore, using network medicine analysis of a biomarker risk panel from plasma of patients with PAH, we demonstrated that complement signaling can serve as a prognostic factor for clinical outcome in PAH. [8]nan [1] nan [2] nan [3] nan [4] nan [5] nan [6] 이펙터 T 림프구에서 발현되는 C3aR 및 C5aR을 통한 보체 신호전달은 사이토카인 인터루킨-10(IL-10)의 생성을 방지합니다. [7] 또한 PAH 환자의 혈장에서 바이오마커 위험 패널의 네트워크 의학 분석을 사용하여 보체 신호가 PAH의 임상 결과에 대한 예후 인자로 작용할 수 있음을 입증했습니다. [8]
complement signaling pathway
RT-PCR results showed that mRNA expression levels of C1qA, C3, C5 and C9 related to the complement signaling pathway were higher in LGBLEL tissues than in orbital CH (P<0. [1] This review will expound the the role of complement signaling pathway in the pathogenesis of NMO, and provide reference for a more in-depth understanding and clinical treatments of NMO. [2] The study’s results reinforce the need for more investigation to assess the impact of therapeutic interventions targeted at the complement signaling pathways in age-related macular degeneration. [3]nan [1] 이 리뷰는 NMO의 발병 기전에서 보체 신호 전달 경로의 역할을 설명하고 NMO에 대한 보다 심층적인 이해와 임상 치료를 위한 참고 자료를 제공할 것입니다. [2] 이 연구의 결과는 연령 관련 황반변성에서 보체 신호 전달 경로를 표적으로 하는 치료 중재의 영향을 평가하기 위한 더 많은 조사의 필요성을 강화합니다. [3]