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The Potential of Flavonoids for the Treatment of Neurodegenerative Diseases

Identification of schizophrenia related biological pathways across eight brain regions

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Low Toxicological Impact of Commercial Pristine Multi-Walled Carbon Nanotubes on the Yeast Saccharomyces cerevisiae

Mimicking cigarette smoke exposure to assess cutaneous toxicity.

Dependence of Graphene Oxide (GO) Toxicity on Oxidation Level, Elemental Composition, and Size

Prenatal treatment with rapamycin restores enhanced hippocampal mGluR-LTD and mushroom spine size in a Down’s syndrome mouse model

Construction of Mode of Action for Cadmium-Induced Renal Tubular Dysfunction Based on a Toxicity Pathway-Oriented Approach

Current opinion on the pharmacogenomics of paclitaxel-induced toxicity

Effect of Health Shocks on Poverty Status in South Korea: Exploring the Mechanism of Medical Impoverishment.

Harnessing Electrical Power from Hybrid Biomass-Solid Waste Energy Resources for Microgrids in Underdeveloped and Developing Countries

In Vivo Cigarette Smoke Exposure to Examine the Expression of Genes Involved in the Inflammatory Response in the Mouse Uterus.

Systematic analysis of chemical-protein interactions from zebrafish embryo by proteome-wide thermal shift assay, bridging the gap between molecular interactions and toxicity pathways.

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Fish tissue accumulation and proteomic response to microcystins is species-dependent.

Exploring the biological domain of the neural embryonic stem cell test (ESTn): morphogenetic regulators, Hox genes and cell types, and their usefulness as biomarkers for embryotoxicity screening.

Sleep and Alzheimer’s Disease: Shared Genetic Risk Factors, Drug Targets, Molecular Mechanisms, and Causal Effects

Comprehensive Analyses of circRNA Expression Profiles and Function Prediction in Chicken Cecums After Eimeria tenella Infection

Mechanism of copper nanoparticle toxicity in rainbow trout olfactory mucosa.

Subcellular Distribution of Dietary Methyl-Mercury in Gammarus fossarum and Its Impact on the Amphipod Proteome.

Cyanotoxins within and Outside of Microcystis aeruginosa Cause Adverse Effects in Rainbow Trout (Oncorhynchus mykiss).

Applying assessments of adaptive capacity to inform natural-resource management in a changing climate.

Analysis of The Expression And Prognosis For Leukocyte Immunoglobulin-Like Receptor Subfamily B In Human Liver Cancer

A toxicity pathway-based approach for modeling the mode of action framework of lead-induced neurotoxicity.

Genetic variation and urine cadmium levels: ABCC1 effects in the Strong Heart Family Study.

Social context-dependent singing alters molecular markers of synaptic plasticity signaling in finch basal ganglia Area X

Age affects temporal response, but not durability, to serial ketamine infusions for treatment refractory depression.

Toward regulatory acceptance and improving the prediction confidence of in silico approaches: a case study of genotoxicity

Identification of toxicity pathway of diesel particulate matter using AOP of PPARγ inactivation leading to pulmonary fibrosis.

Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways

Zebrafish Models of Cancer Therapy-Induced Cardiovascular Toxicity

A mechanistic model to study the kinetics and toxicity of salicylic acid in the kidney of four virtual individuals

Development, scrutiny, and modulation of transient reporter gene assays of the xenobiotic metabolism pathway in zebrafish hepatocytes.

In vivo and in vitro α-amanitin metabolism studies using molecular networking.

Examining the Relationship between Concussion and Neurodegenerative Disorders: A Review on Amyotrophic Lateral Sclerosis (ALS) and Alzheimer’s Disease (AD)

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Toxicity pathways of lipid metabolic disorders induced by typical replacement flame retardants via data-driven analysis, in silico and in vitro approaches.

The exposome in practice: an exploratory panel study of biomarkers of air pollutant exposure in Chinese people aged 60-69 years (China BAPE Study).

Household air pollution and blood markers of inflammation: A cross-sectional analysis.

Vagal Nerve Stimulation Protects Against Cerebral Ischemia–Reperfusion Injury in Rats by Inhibiting Autophagy and Apoptosis

Cellular repair mechanisms triggered by exposure to silver nanoparticles and ionic silver in embryonic zebrafish cells

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[Research progress on exposure levels and toxic pathways of typical persistent organic pollutants in foods].

Genome-Wide Analysis of Alternative Splicing in Zea mays during Maize Iranian Mosaic Virus Infection

In vitro bioassays to assess drinking water quality

Acute alcohol consumption-induced let-7a inhibition exacerbates hepatic apoptosis by regulating Rb1 in mice.

Common Gene Expression Patterns in Environmental Model Organisms Exposed to Engineered Nanomaterials: A Meta-Analysis

Long-Term Electricity Scenarios for the MENA Region: Assessing the Preferences of Local Stakeholders Using Multi-Criteria Analyses

Effect-based methods in combination with state-of-the-art chemical analysis for assessment of water quality as integrated approach.

Insights into histidine kinase activation mechanisms from the monomeric blue light sensor EL346

Progesterone Protects Prefrontal Cortex in Rat Model of Permanent Bilateral Common Carotid Occlusion via Progesterone Receptors and Akt/Erk/eNOS

Extracts of passive samplers deployed in variably contaminated wetlands in the Athabasca oil sands region elicit biochemical and transcriptomic effects in avian hepatocytes.

Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial

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Modes of action and adverse effects of gamma radiation in an aquatic macrophyte Lemna minor.

Relationship of Antiphospholipid Antibodies to Risk of Dementia: A Systematic Review.

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Waste Constituent Pathways

Comparative study of Cu uptake and early transcriptome responses in the green microalga Chlamydomonas reinhardtii and the macrophyte Elodea nuttallii.

The puzzling issue of silica toxicity: are silanols bridging the gaps between surface states and pathogenicity?

A novel human 3D lung microtissue model for nanoparticle-induced cell-matrix alterations

When Are Adverse Outcome Pathways and Associated Assays “Fit for Purpose” for Regulatory Decision‐Making and Management of Chemicals?

Heterogeneity in Biodistribution and Cytotoxicity of Silver Nanoparticles in Pulmonary Adenocarcinoma Human Cells

Vagus nerve stimulation as a promising adjunctive treatment for ischemic stroke

Embracing Systems Toxicology at Single-Cell Resolution.

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Transcriptomic analysis reveals dose-dependent modes of action of benzo(a)pyrene in polar cod (Boreogadus saida).

Dorsal Amygdala Neurotrophin-3 Decreases Anxious Temperament in Primates

Assessment of mixture toxicity of (tri)azoles and their hepatotoxic effects in vitro by means of omics technologies

Bioenergetics-adverse outcome pathway: Linking organismal and suborganismal energetic endpoints to adverse outcomes.

Ecotoxicoproteomics: A decade of progress in our understanding of anthropogenic impact on the environment.

Gene expression profiling in blood from cerebral malaria patients and mild malaria patients living in Senegal

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PM2.5- and PM10-bound polycyclic aromatic hydrocarbons (PAHs) in the residential area near coal-fired power and steelmaking plants of Taichung City, Taiwan: In vitro-based health risk and source identification.

Neuroprocessing Mechanisms of Music during Fetal and Neonatal Development: A Role in Neuroplasticity and Neurodevelopment

Mechanisms of haemolysis-induced kidney injury

Effects of cadmium, inorganic mercury and methyl-mercury on the physiology and metabolomic profiles of shoots of the macrophyte Elodea nuttallii.

All-trans Retinoic Acid Disrupts Development in Ex Vivo Cultured Fetal Rat Testes. II: Modulation of Mono-(2-ethylhexyl) Phthalate Toxicity

Investigating cell type specific mechanisms contributing to acute oral toxicity.

Prioritization of hazards of novel flame retardants using the mechanistic toxicology information from ToxCast and Adverse Outcome Pathways

Application of the adverse outcome pathway framework to genotoxic modes of action

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