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Checkpoint Kinase sentence examples within ataxia telangiectasia mutated



Circadian rhythm genes in cancer: insight into their functions and regulation involving noncoding RNAs


Molecular basis of human ATM kinase inhibition.

Checkpoint Kinase sentence examples within cell cycle arrest



Oncogenic WIP1 phosphatase attenuates the DNA damage response and sensitizes p53 mutant Jurkat cells to apoptosis


A Molecular Dynamics of Radiation-Induced DNA Damage Response: Exploring the Pathways of Signaling, Repair, and Cell Death

Checkpoint Kinase sentence examples within serine threonine kinase



UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma.


CHK2 Inhibition Provides a Strategy to Suppress Hematologic Toxicity from PARP Inhibitors



Checkpoint Kinase sentence examples within cyclin dependent kinase



Effects of different doses of X-ray irradiation on cell apoptosis, cell cycle, DNA damage repair and glycolysis in HeLa cells


CDK and Mec1/Tel1-catalyzed phosphorylation of Sae2 regulate different responses to DNA damage

Checkpoint Kinase sentence examples within orally bioavailable inhibitor



High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers


A first-in-human phase I/II trial of SRA737 (a Chk1 Inhibitor) in subjects with advanced cancer

Checkpoint Kinase sentence examples within premature mitotic entry



Checkpoint kinase 1 is essential for fetal and adult hematopoiesis


Checkpoint kinase 1 is essential for fetal and adult hematopoiesis

Checkpoint Kinase sentence examples within cell cycle progression



ATR activation is regulated by dimerization of ATR activating proteins


GDC-0575, a CHK1 Inhibitor, Impairs the Development of Colitis and Colitis-Associated Cancer by Inhibiting CCR2+ Macrophage Infiltration in Mice

Checkpoint Kinase sentence examples within cell division cycle



Screening key genes and signaling pathways in colorectal cancer by integrated bioinformatics analysis


Glycerin Monostearate Aggravates Male Reproductive Toxicity Caused by Di(2-ethylhexyl) Phthalate in Rats

Checkpoint Kinase sentence examples within Cycle Checkpoint Kinase



Determination of CHK1 Cellular Localization by Immunofluorescence Microscopy.


Ovarian cancer: new strategies and emerging targets for the treatment of patients with advanced disease

Checkpoint Kinase sentence examples within Damage Checkpoint Kinase



MTBP phosphorylation controls DNA replication origin firing


Regulation of Pkc1 Hyper-Phosphorylation by Genotoxic Stress

Checkpoint Kinase sentence examples within G2 Checkpoint Kinase



SETD2 Deficiency and miR-21: Potent Therapeutic Targets in NUT Midline Carcinoma


Circ-SNAP47 (hsa_circ_0016760) and miR-625-5p are regulators of WEE1 in regulation of chemoresistance, growth and invasion of DDP-tolerant NSCLC cells via ceRNA pathway.

Checkpoint Kinase sentence examples within Phosphorylated Checkpoint Kinase



Perilla frutescens Extracts Enhance DNA Repair Response in UVB Damaged HaCaT Cells


MP57-03 COMBINATION OF ANDROGEN RECEPTOR INHIBITOR AND CISPLATIN, AN EFFECTIVE TREATMENT STRATEGY FOR UROTHELIAL CARCINOMA OF THE BLADDER

Checkpoint Kinase sentence examples within Metabolic Checkpoint Kinase



High expression of mTOR signaling in granulomatous lesions is not predictive for the clinical course of sarcoidosis.


N-myristoylation of AMPK controls T cell inflammatory function

Checkpoint Kinase sentence examples within M Checkpoint Kinase



An Adenovirus early region 4 deletion mutant induces G2/M arrest via ATM activation and reduces expression of the mitotic marker phosphorylated (ser10) histone 3.


Antitumor effect of WEE1 blockade as monotherapy or in combination with cisplatin in urothelial cancer

Checkpoint Kinase sentence examples within Mitotic Checkpoint Kinase



Androgen receptor negatively regulates mitotic checkpoint signaling to induce docetaxel resistance in castration-resistant prostate cancer.


Hsp90 chaperone code and the tumor suppressor VHL cooperatively regulate the mitotic checkpoint.

Checkpoint Kinase sentence examples within Chk1 Checkpoint Kinase



Loss of HMCES is synthetic lethal with APOBEC activity in cancer cells


Loss of the abasic site sensor HMCES is synthetic lethal with the activity of the APOBEC3A cytosine deaminase in cancer cells

Checkpoint Kinase sentence examples within Assembly Checkpoint Kinase



High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers


Phospho-regulation of the Shugoshin - Condensin interaction at the centromere in budding yeast

Checkpoint Kinase sentence examples within Effector Checkpoint Kinase



UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma.


Abstract 3498: Highly specific macrocyclic ATR inhibitors for the targeted treatment of a broad spectrum of cancers showing lack of anemia or neutropenia in pre-clinical animal models

Checkpoint Kinase sentence examples within Replication Checkpoint Kinase



Checkpoint-mediated DNA polymerase ε exonuclease activity curbing counteracts resection-driven fork collapse.


A mechanism for Rad53 to couple leading- and lagging-strand DNA synthesis under replication stress in budding yeast

Checkpoint Kinase sentence examples within checkpoint kinase 1



Adverse Cerebral Cardiovascular Events Associated With Checkpoint Kinase 1 Inhibitors: A Systemic Review.


Ovarian cancer: new strategies and emerging targets for the treatment of patients with advanced disease

Checkpoint Kinase sentence examples within checkpoint kinase 2



DNA Damage Response Protein CHK2 Regulates Metabolism in Liver Cancer


Drosophila female germline stem cells undergo mitosis without nuclear breakdown

Checkpoint Kinase sentence examples within checkpoint kinase rad53



A novel role for Dun1 in the regulation of origin firing upon hyper-acetylation of H3K56


LncRNA DINOR is a virulence factor and global regulator of stress responses in Candida auris.

Checkpoint Kinase sentence examples within checkpoint kinase atr



ADAR2-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair


San1 deficiency leads to cardiomyopathy due to excessive R-loop-associated DNA damage and cardiomyocyte hypoplasia.

Checkpoint Kinase sentence examples within checkpoint kinase mps1



Hsp90 chaperone code and the tumor suppressor VHL cooperatively regulate the mitotic checkpoint.


High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers

Checkpoint Kinase sentence examples within checkpoint kinase wee1



Targeting MUS81 promotes the anticancer effect of WEE1 inhibitor and immune checkpoint blocking combination therapy via activating cGAS/STING signaling in gastric cancer cells


Genome-wide CRISPR-Cas9 screen reveals selective vulnerability of ATRX-mutant cancers to WEE1 inhibition.

Checkpoint Kinase sentence examples within checkpoint kinase ataxium



Molecular basis of human ATM kinase inhibition.


Class 1 Histone Deacetylases and Ataxia-Telangiectasia Mutated Kinase Control the Survival of Murine Pancreatic Cancer Cells upon dNTP Depletion

Checkpoint Kinase sentence examples within checkpoint kinase chk1



Synthesis, X-Ray, Spectroscopic characterization, Hirshfeld surface analysis, DFT calculation and Molecular docking investigations of a novel 7-phenyl-2,3,4,5-tetrahydro-1H-1,4- diazepin-5-one derivative


The Deubiquitinating Enzyme USP37 Stabilizes CHK1 to Promote the Cellular Response to Replication Stress

Checkpoint Kinase sentence examples within checkpoint kinase promoting



Checkpoint Regulation of Nuclear Tos4 Defines S Phase Arrest in Fission Yeast


Checkpoint regulation of nuclear Tos4 defines S phase arrest in fission yeast

Checkpoint Kinase sentence examples within checkpoint kinase inhibitor



Elucidation of Novel Therapeutic Targets for Breast Cancer with ESR1-CCDC170 Fusion


Glucocorticoids and checkpoint tyrosine kinase inhibitors stimulate rat pancreatic beta cell proliferation differentially

Checkpoint Kinase sentence examples within checkpoint kinase complex



N-myristoylation of AMPK controls T cell inflammatory function


c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis

Checkpoint Kinase sentence examples within checkpoint kinase mec1



A mechanism for Rad53 to couple leading- and lagging-strand DNA synthesis under replication stress in budding yeast


Quantitative sensing and signalling of single-stranded DNA during the DNA damage response

Checkpoint Kinase sentence examples within checkpoint kinase consensu



MTBP phosphorylation controls DNA replication origin firing


Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3ATR kinase is essential in the absence of Rqh1BLM helicase


Mck1 kinase is a new player in the DNA damage checkpoint pathway



Abstract 2541: Mastl regulates EGFR signaling to promote pancreatic cancer progression



Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents



Cold Physical Plasma Modulates p53 and Mitogen-Activated Protein Kinase Signaling in Keratinocytes



IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response



Prexasertib, a checkpoint kinase inhibitor: from preclinical data to clinical development



A comparative anticancer study on procyanidin C1 against receptor positive and receptor negative breast cancer



Checkpoint Kinase 1 Inhibition Enhances Cisplatin Cytotoxicity and Overcomes Cisplatin Resistance in SCLC by Promoting Mitotic Cell Death.



Human papillomavirus type 8 oncoproteins E6 and E7 cooperate in downregulation of the cellular checkpoint kinase‐1



Chk1 Inhibitor MK-8776 Restores the Sensitivity of Chemotherapeutics in P-glycoprotein Overexpressing Cancer Cells



Three-Dimensional Analysis of Binding Sites for Predicting Binding Affinities in Drug Design



Prexasertib (LY2606368) reduces clonogenic survival by inducing apoptosis in primary patient‐derived osteosarcoma cells and synergizes with cisplatin and talazoparib


Checkpoint Kinase 체크포인트 키나제


Checkpoint Kinase 체크포인트 키나제
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