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Chemically Designed Nanoscale Materials for Controlling Cellular Processes.



Molecular Mechanisms of Borrelia burgdorferi Phagocytosis and Intracellular Processing by Human Macrophages



Caveolae-Mediated Endocytosis Drives Robust siRNA Delivery of Polymeric Nanoparticles to Macrophages.



A high-throughput Galectin-9 imaging assay for quantifying nanoparticle uptake, endosomal escape and functional RNA delivery



Two-Pore Channels Regulate Expression of Various Receptors and Their Pathway-Related Proteins in Multiple Ways



The SARS-CoV-2 envelope and membrane proteins modulate maturation and retention of the spike protein, allowing assembly of virus-like particles



Unlocking the potential of antibody–drug conjugates for cancer therapy



Phagocytosis and the antigen-processing abilities of macrophages derived from monocytes in spinal tuberculosis patients



Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles



In vivo cleavage of solubility tags as a tool to enhance the levels of soluble recombinant proteins in Escherichia coli



Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter.



Functions of the (pro)renin receptor (Atp6ap2) at molecular and system levels: pathological implications in hypertension, renal and brain development, inflammation, and fibrosis.



Is It Time to Use Modeling of Cellular Transporter Homeostasis to Inform Drug-Drug Interaction Studies: Theoretical Considerations.



Molecular markers of brain cholesterol homeostasis are unchanged despite a smaller brain mass in a mouse model of cholesteryl ester storage disease.



Giantin is required for intracellular N-terminal processing of type I procollagen



Targeting Non-Canonical Pathways as a Strategy to Modulate the NIS Symporter



Rational design for controlled release of Dicer-substrate siRNA harbored in phi29 pRNA-based nanoparticles



In vivo cleavage of solubility tags as a tool to enhance the levels of soluble recombinant proteins in Escherichia coli



Responsive Antibody Conjugates Enable Quantitative Determination of Intracellular Bond Degradation Rate.



Polymer design and component selection contribute to uptake, distribution & trafficking behaviours of polyethylene glycol hyperbranched polymers in live MDA-MB-468 breast cancer cells.



TOWARDS THE RATIONAL DESIGN AND APPLICATION OF POLYMERS FOR GENE THERAPY: INTERNALIZATION AND INTRACELLULAR FATE



Plant-derived virus-like particle vaccines drive cross-presentation of influenza A hemagglutinin peptides by human monocyte-derived macrophages



C1R Mutations Trigger Constitutive Complement 1 Activation in Periodontal Ehlers-Danlos Syndrome



Nanocarriers and immune cells



Induction of MET Receptor Tyrosine Kinase Down-regulation through Antibody-mediated Receptor Clustering



Congenital hypofibrinogenemia associated with a novel heterozygous nonsense mutation in the globular C-terminal domain of the γ-chain (p.Glu275Stop)



Supraphysiological vitamin B12 serum concentrations without supplementation: the pitfalls of interpretation



Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability



Familial early-onset hyperuricemia and gout associated with a newly identified dysfunctional variant in urate transporter ABCG2



HER2-Overexpressing/Amplified Breast Cancer as a Testing Ground for Antibody–Drug Conjugate Drug Development in Solid Tumors



How thyroid hormones and their inhibitors affect cartilage growth and shape in the frog Xenopus laevis



A Systems Pharmacology Model for Drug Delivery to Solid Tumors by Antibody-Drug Conjugates: Implications for Bystander Effects


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