Introduction to Whole Brain Radiotherapy

Sentence Examples

Discover more insights into Whole Brain Radiotherapy

Keywords frequently search together with Whole Brain Radiotherapy

Narrow sentence examples with built-in keyword filters

Whole Brain Radiotherapy sentence examples within non small cell

non small cell

The present study aimed to assess the value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in predicting the treatment outcomes of whole-brain radiotherapy (WBRT) and gefitinib in brain metastases from non-small cell lung cancer (NSCLC) from the perspectives of response rate and short- and long-term efficacy.

Predictive effect of DCE-MRI and DWI in brain metastases from NSCLC

non small cell

OBJECTIVE The aim of the present work was to investigate the response and safety of whole-brain radiotherapy (WBRT) plus temozolomide (TMZ) for patients with brain metastases of non-small-cell lung cancer (NSCLC).

Response and safety of whole-brain radiotherapy plus temozolomide for patients with brain metastases of non-small-cell lung cancer: A meta-analysis.

More non small cell sentences More Sentences

Whole Brain Radiotherapy sentence examples within include high dose

include high dose

Potential options include high-dose therapy with haematopoietic stem cell consolidation, non-myeloablative chemotherapy and whole-brain radiotherapy.

Advances in treatment of elderly primary central nervous system lymphoma.

include high dose

Potential consolidation treatment options include high-dose therapy with stem cell consolidation, non-myeloablative chemotherapy, or whole-brain radiotherapy (WBRT) but the increased risk of delayed neurotoxicity associated with the latter means this is utilized less frequently.

Treatment of elderly patients with primary CNS lymphoma

More include high dose sentences More Sentences

Whole Brain Radiotherapy sentence examples within small cell lung

small cell lung

INTRODUCTION The historical standard of care for brain metastases (BMs) from small cell lung cancer (SCLC) has been whole-brain radiotherapy (WBRT).

Care Patterns for Stereotactic Radiosurgery in Small Cell Lung Cancer Brain Metastases.

small cell lung

Diagnosis-specific survival scores including a new score developed in 157 patients with brain metastases from small-cell lung cancer (SCLC) receiving whole-brain radiotherapy (WBRT) with 30 Gy in 10 fractions (WBRT-30-SCLC) were compared.

Comparison of Diagnosis-Specific Survival Scores for Patients with Small-Cell Lung Cancer Irradiated for Brain Metastases

More small cell lung sentences More Sentences

Learn more from Whole Brain Radiotherapy

Whole Brain Radiotherapy sentence examples within 3 g m2

3 g m2

Methods This was a single-center, retrospective cohort study of consecutive newly diagnosed immunocompetent PCNSL patients treated with HD-MTX (5 cycles of 3 g/m2 every 2 weeks) followed by consolidation whole-brain radiotherapy (WBRT) and cytarabine (2 cycles of 3 g/m2/d for 2 days every 3 weeks) from January 2013 to December 2020.

OUTCOME OF PATIENTS WITH NEWLY DIAGNOSED PRIMARY CNS LYMPHOMA AFTER HIGH‐DOSE METHOTREXATE FOLLOWED BY CONSOLIDATION WHOLE‐BRAIN RADIOTHERAPY AND CYTARABINE

3 g m2

This was a single-center, retrospective cohort study of consecutive newly diagnosed immunocompetent PCNSL patients treated with HD-MTX (5 cycles of 3 g/m2 every 2 weeks) followed by consolidation whole-brain radiotherapy (WBRT) and cytarabine (2 cycles of 3 g/m2/d for 2 days every 3 weeks) from January 2013 to December 2020.

Outcome of patients with newly diagnosed primary CNS lymphoma after high-dose methotrexate followed by consolidation whole-brain radiotherapy and cytarabine: an 8-year cohort study

More 3 g m2 sentences More Sentences

More Whole Brain Radiotherapy sentence examples
10.21873/invivo.12412

Patients and Methods: This was a retrospective single-institution analysis of 249 patients, managed with whole-brain radiotherapy for brain metastases.

Validation of a Graded Prognostic Model in Patients With Brain Metastases Treated With Whole-brain Radiotherapy Instead of Radiosurgery

More Whole Brain Radiotherapy sentence examples
10.1016/j.ctro.2021.01.003

• A history of whole-brain radiotherapy did not increase the risk.

The individual risk of symptomatic radionecrosis after brain metastasis radiosurgery is predicted by a continuous function of the V12Gy☆

More Whole Brain Radiotherapy sentence examples
10.21037/AOL-20-37

Studies that assessed cognitive functions systematically months to years after HD-MTXbased chemotherapy and consolidation whole-brain radiotherapy (WBRT) reported cognitive impairment and white matter abnormalities in most patients.

Narrative review of primary central nervous system lymphoma: treatment-related neurotoxicity

More Whole Brain Radiotherapy sentence examples
10.1159/000518528

After 3 relapses and intensive treatment with multiple chemotherapy regimens and whole-brain radiotherapy, she received off-label treatment with the Bruton tyrosine kinase inhibitor ibrutinib, responded well, achieved a complete remission, and is progression-free for now >3 years.

Sustained Complete Remission in Multi-Relapsed Primary CNS Lymphoma Treated with Ibrutinib Monotherapy: A Case Report

More Whole Brain Radiotherapy sentence examples
10.1007/s00117-021-00894-4

Protection of the hippocampus during whole-brain radiotherapy reduces therapy toxicity.

[Surgical treatment and radiation therapy of brain metastases].

More Whole Brain Radiotherapy sentence examples
10.21037/apm-21-557

Then, the patient received 10 cycles of chemotherapy with high-dose methotrexate (HD-MTX) and whole-brain radiotherapy.

Primary central nervous system ALK-negative anaplastic large cell lymphoma: a case report and literature review.

More Whole Brain Radiotherapy sentence examples
10.1007/s12185-021-03107-9

After 3 cycles of MPV (methotrexate, procarbazine, vincristine) followed by whole-brain radiotherapy, her cognitive impairment improved.

Early central nervous system relapse of monomorphic epitheliotropic intestinal T-cell lymphoma after cord blood transplantation

More Whole Brain Radiotherapy sentence examples
10.1111/bjh.17799

Potential options include high-dose therapy with haematopoietic stem cell consolidation, non-myeloablative chemotherapy and whole-brain radiotherapy.

Advances in treatment of elderly primary central nervous system lymphoma.

More Whole Brain Radiotherapy sentence examples
10.1016/j.radonc.2021.06.026

Where possible, a comparison with whole-brain radiotherapy (WBRT) was performed.

Stereotactic radiosurgery for brain metastases from small cell lung cancer without prior whole-brain radiotherapy: a meta-analysis.

More Whole Brain Radiotherapy sentence examples
10.21037/AOL-20-30

Potential consolidation treatment options include high-dose therapy with stem cell consolidation, non-myeloablative chemotherapy, or whole-brain radiotherapy (WBRT) but the increased risk of delayed neurotoxicity associated with the latter means this is utilized less frequently.

Treatment of elderly patients with primary CNS lymphoma

More Whole Brain Radiotherapy sentence examples
10.1515/med-2021-0260

The present study aimed to assess the value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in predicting the treatment outcomes of whole-brain radiotherapy (WBRT) and gefitinib in brain metastases from non-small cell lung cancer (NSCLC) from the perspectives of response rate and short- and long-term efficacy.

Predictive effect of DCE-MRI and DWI in brain metastases from NSCLC

More Whole Brain Radiotherapy sentence examples
10.1097/MD.0000000000027543

Patient concerns: We present a case of a 55-year-old male patient suffering from brain metastases, who had previously received whole-brain radiotherapy (WBRT) and first CyberKnife Stereotactic Radiotherapy (CKSRT) for metastases, presented with a recurrence of metastasis and new lesions in the brain.

Re-irradiation of multiple brain metastases using CyberKnife stereotactic radiotherapy

More Whole Brain Radiotherapy sentence examples
10.1002/hon.35_2881

Methods This was a single-center, retrospective cohort study of consecutive newly diagnosed immunocompetent PCNSL patients treated with HD-MTX (5 cycles of 3 g/m2 every 2 weeks) followed by consolidation whole-brain radiotherapy (WBRT) and cytarabine (2 cycles of 3 g/m2/d for 2 days every 3 weeks) from January 2013 to December 2020.

OUTCOME OF PATIENTS WITH NEWLY DIAGNOSED PRIMARY CNS LYMPHOMA AFTER HIGH‐DOSE METHOTREXATE FOLLOWED BY CONSOLIDATION WHOLE‐BRAIN RADIOTHERAPY AND CYTARABINE

More Whole Brain Radiotherapy sentence examples
10.1038/s41598-021-87357-x

Propensity score matching (PSM) was used to evaluate survival according to RT modality, which included whole-brain radiotherapy (WBRT) and/or stereotactic radiosurgery (SRS).

Radiotherapy for brain metastasis and long-term survival

More Whole Brain Radiotherapy sentence examples
10.1007/s00277-021-04548-2

We performed a retrospective, multi-centre analysis of 14 patients with pCNS-PTLD after solid organ transplantation (SOT) treated in the prospective German PTLD registry with reduction of immunosuppression (RI), whole-brain radiotherapy (WBRT), and concurrent systemic rituximab between 2001 and 2018.

Reduction of immunosuppression combined with whole-brain radiotherapy and concurrent systemic rituximab is an effective yet toxic treatment of primary central nervous system post-transplant lymphoproliferative disorder (pCNS-PTLD): 14 cases from the prospective German PTLD registry

More Whole Brain Radiotherapy sentence examples
10.1016/j.esmoop.2021.100161

LT comprised stereotactic (SRT; n = 40; 34%) or whole-brain radiotherapy (WBRT; n = 77; 66%), while neurosurgical resection was carried out in 19 cases.

Effect of timing, technique and molecular features on brain control with local therapies in oncogene-driven lung cancer

More Whole Brain Radiotherapy sentence examples
10.1007/s11864-021-00911-7

Moreover, these drugs may delay the use of local therapies, such as stereotactic radiosurgery (SRS) or whole-brain radiotherapy (WBRT).

Systemic Therapy for Lung Cancer Brain Metastases

More Whole Brain Radiotherapy sentence examples
10.1186/s12974-021-02290-0

Pharmacological depletion of microglia during whole-brain radiotherapy prevents synaptic loss and long-term recognition memory deficits.

Functional role of brain-engrafted macrophages against brain injuries

More Whole Brain Radiotherapy sentence examples
10.1159/000518848

This review explores the impact of whole-brain radiotherapy (WBRT) or stereotactic radiosurgery (SRS) on cognition.

The Impact of Stereotactic or Whole Brain Radiotherapy on Neurocognitive Functioning in Adult Patients with Brain Metastases: A Systematic Review and Meta-Analysis.

More Whole Brain Radiotherapy sentence examples
10.7759/cureus.16537

Progression after front-line chemotherapy is common, and whole-brain radiotherapy (WBRT) is a standard salvage treatment as there is a concern that localized treatment fields would not prevent out-of-field recurrences.

Stereotactic Radiotherapy for Recurrent Post-Transplant Primary Central Nervous System Lymphoma

More Whole Brain Radiotherapy sentence examples
10.1016/j.canrad.2020.06.037

6%), whole-brain radiotherapy (2 patients, 2.

[Concurrent radiation therapy and dual HER2 blockade in breast cancer: Assessment of toxicity].

More Whole Brain Radiotherapy sentence examples
10.3390/cancers13153682

Traditionally, due to the limited efficacy of cytotoxic chemotherapy, treatment strategies are focused on local treatments alone, such as whole-brain radiotherapy (WBRT), stereotactic radiosurgery (SRS), and resection.

Integration of Systemic Therapy and Stereotactic Radiosurgery for Brain Metastases

More Whole Brain Radiotherapy sentence examples
10.21873/anticanres.15221

Postoperative therapy consisted of whole-brain radiotherapy in 4 cases and molecular targeted therapy in 4, with 6 patients not receiving any postoperative treatment.

Effectiveness of Palliative Cerebrospinal Fluid Shunting for Patients With Leptomeningeal Carcinomatosis-related Hydrocephalus

More Whole Brain Radiotherapy sentence examples
10.1159/000513975

, after whole-brain radiotherapy.

Recursive Partitioning Analysis of Systemic Therapy after Radiotherapy in Patients with Brain Metastases

More Whole Brain Radiotherapy sentence examples
10.1177/1533033820986824

Purpose: The aim of this study is to comparatively examine the possibility of reducing the exposure dose to organs at risk, such as the hippocampus and lens, and improving the dose distribution of the planned target volume with and without the use of a head-tilting base plate in hippocampal-sparing whole-brain radiotherapy using tomotherapy.

Use of a Head-Tilting Baseplate During Tomotherapy to Shorten the Irradiation Time and Protect the Hippocampus and Lens in Hippocampal Sparing-Whole Brain Radiotherapy

More Whole Brain Radiotherapy sentence examples
10.1038/s41598-021-98530-7

To optimize the collimator angles in dual-arc volumetric modulated arc therapy (VMAT) plans for whole-brain radiotherapy with hippocampus and inner ear sparing (HIS-WBRT).

Optimization of collimator angles in dual-arc volumetric modulated arc therapy planning for whole-brain radiotherapy with hippocampus and inner ear sparing

More Whole Brain Radiotherapy sentence examples
10.4103/ijc.IJC_36_19

On the other hand, with respect to radiotherapy dose, among older patient group, greater hypofractionation and whole-brain radiotherapy was applied (P = 0.

Factors affecting survival in glioblastoma patients below and above 65 years of age: A retrospective observational study

More Whole Brain Radiotherapy sentence examples
10.1007/s40278-021-91299-9

The metastatic lesions in the body regressed, but the brain metastasis progressed and was treated with whole-brain radiotherapy and concomitant temozolomide.

Immune checkpoint inhibitors

More Whole Brain Radiotherapy sentence examples
10.12998/wjcc.v9.i24.7205

He had previously received paclitaxel/carboplatin, gemcitabin/ vinorelbine chemotherapy, stereotactic radiosurgery for brain metastasis, and whole-brain radiotherapy as treatment for NSCLC.

Therapy-related myeloid leukemia during erlotinib treatment in a non-small cell lung cancer patient: A case report

More Whole Brain Radiotherapy sentence examples
10.1007/s00761-021-00913-y

Protection of the hippocampus during whole-brain radiotherapy reduces therapy toxicity.

Chirurgische Behandlung und Strahlentherapie von Hirnmetastasen

More Whole Brain Radiotherapy sentence examples
10.3389/fonc.2021.665652

The therapeutic regimen then consisted of whole-brain radiotherapy, anti-angiogenesis therapy, and immunotherapy.

Dural and Multiple Brain Metastases From Basaloid Nasopharyngeal Carcinoma: Case Report and Literature Review

More Whole Brain Radiotherapy sentence examples
10.21037/apm-21-321

Intrathecal chemotherapy (ITC), whole-brain radiotherapy (WBRT) with a simultaneous integrated boost (SIB) followed by Osimertinib was initiated.

Successful treatment using targeted therapy, radiotherapy, and intrathecal chemotherapy in a patient with leptomeningeal metastasis with an epidermal growth factor receptor exon 20 insertion mutation: a case report.

More Whole Brain Radiotherapy sentence examples
10.1186/s12981-021-00403-6

HAART was initiated with whole-brain radiotherapy (WBRT), and the patient declined systemic chemotherapy.

Long-term remission of AIDS-related primary central nervous system lymphoma in a patient under antiretroviral therapy: a case report and review of the literature

More Whole Brain Radiotherapy sentence examples
10.1007/s10637-021-01105-6

The craniocerebral lesions attained partial remission after whole-brain radiotherapy and targeted combined immunotherapy, and other distant metastases completely disappeared after targeted combined immunotherapy (anlotinib and camrelizumab), indicating significant treatment efficacy.

Combined immunotherapy and targeted treatment for primary alveolar soft part sarcoma of the lung: case report and literature review

More Whole Brain Radiotherapy sentence examples
10.1016/j.cllc.2021.07.003

INTRODUCTION The historical standard of care for brain metastases (BMs) from small cell lung cancer (SCLC) has been whole-brain radiotherapy (WBRT).

Care Patterns for Stereotactic Radiosurgery in Small Cell Lung Cancer Brain Metastases.

More Whole Brain Radiotherapy sentence examples
10.1093/noajnl/vdab070.039

Treatments including systemic therapy, whole-brain radiotherapy (WBRT), stereotactic radiosurgery (SRS), and intrathecal chemotherapy with Methotrexate (IT MTX) were recorded.

OMRT-15. Multidisciplinary management of non-small cell lung cancer patients with leptomeningeal metastasis in the TKI era

More Whole Brain Radiotherapy sentence examples
10.1177/15330338211034269

Whole-brain radiotherapy (WBRT) is the mainstay of therapy in treating cancer patients with brain metastases, but unfortunately, it might also lead to decline in neurocognitive function.

The Effect of Hippocampal Avoidance Whole Brain Radiotherapy on the Preservation of Long-Term Neurocognitive Function in Non-Small Cell Lung Cancer Patients With Brain Metastasis

More Whole Brain Radiotherapy sentence examples
10.20892/j.issn.2095-3941.2021.0026

OBJECTIVE This study aimed to evaluate the safety, efficacy, and feasibility of the rituximab, fotemustine, pemetrexed, and dexamethasone (R-FPD) regimen followed by whole-brain radiotherapy (WBRT) for patients with primary central nervous system lymphoma (PCNSL).

Fotemustine-based therapy in combination with rituximab as a first-line induction chemotherapy followed by WBRT for newly diagnosed primary central nervous system lymphoma: a prospective phase II trial.

More Whole Brain Radiotherapy sentence examples
10.1177/15330338211045497

Objectives: Hippocampus-sparing whole-brain radiotherapy (HS-WBRT) using tomotherapy is known to provide a better dose distribution than volumetric-modulated arc therapy but requires an extended irradiation time.

Influence of Modulation Factor on Treatment Plan Quality and Irradiation Time in Hippocampus-Sparing Whole-Brain Radiotherapy Using Tomotherapy

More Whole Brain Radiotherapy sentence examples
10.1177/1120672121990570

He had undergone whole-brain radiotherapy with a total dose of 30 Gy over 10 fractions and concurrent chemotherapy with cisplatin and pemetrexed.

Necrosis of the optic nerve and chiasm with safe radiation doses: Report of two rare cases.

More Whole Brain Radiotherapy sentence examples
10.1155/2021/5543939

He received whole-brain radiotherapy followed by the administration of pembrolizumab.

Leptomeningeal Carcinomatosis in Urothelial Carcinoma of the Urinary Bladder: A Report of a Patient with a Fulminant Course Who Died of Cancer after Definitive Therapies

More Whole Brain Radiotherapy sentence examples
10.21037/TRO-19-103

She underwent whole-brain radiotherapy followed by immunotherapy.

Treating leptomeningeal metastases from primary hepatic neuroendocrine carcinoma with combined radiotherapy and immunotherapy: a case report

More Whole Brain Radiotherapy sentence examples
10.1080/00207454.2021.1916490

Whole-brain radiotherapy (WBRT) is one of the standard treatment strategies for NSCLC.

Stereotactic Radiosurgery with Whole Brain Radiotherapy Combined with Bevacizumab in the Treatment of Brain Metastases from NSCLC.

More Whole Brain Radiotherapy sentence examples
10.1155/2021/6661698

52% received whole-brain radiotherapy.

Real-World Study of Cisplatin, Etoposide, and Bleomycin Chemotherapy Regimen in Gestational Trophoblastic Neoplasia

More Whole Brain Radiotherapy sentence examples
10.1016/j.ijrobp.2021.07.467

PURPOSE/OBJECTIVE(S) Local response prediction for brain metastases (BMs) from lung cancer after Whole-Brain Radiotherapy (WBRT) is challenging, as existing criteria are based solely on unidimensional measurements.

MRI-Based Radiomics Signature for the Prediction of Response of Lung Cancer Brain Metastases After Whole-Brain Radio-Therapy.

More Whole Brain Radiotherapy sentence examples
10.1007/s10147-021-01982-0

This was a single-center, retrospective cohort study of consecutive newly diagnosed immunocompetent PCNSL patients treated with HD-MTX (5 cycles of 3 g/m2 every 2 weeks) followed by consolidation whole-brain radiotherapy (WBRT) and cytarabine (2 cycles of 3 g/m2/d for 2 days every 3 weeks) from January 2013 to December 2020.

Outcome of patients with newly diagnosed primary CNS lymphoma after high-dose methotrexate followed by consolidation whole-brain radiotherapy and cytarabine: an 8-year cohort study

More Whole Brain Radiotherapy sentence examples
10.1111/1759-7714.14183

OBJECTIVE The aim of the present work was to investigate the response and safety of whole-brain radiotherapy (WBRT) plus temozolomide (TMZ) for patients with brain metastases of non-small-cell lung cancer (NSCLC).

Response and safety of whole-brain radiotherapy plus temozolomide for patients with brain metastases of non-small-cell lung cancer: A meta-analysis.

More Whole Brain Radiotherapy sentence examples
10.1002/mp.14760

CONCLUSION Our results demonstrated the efficiency of multi-task edge-aware learning in hippocampus segmentation for hippocampal sparing whole-brain radiotherapy.

Automatic Segmentation of Hippocampus in Hippocampal Sparing Whole Brain Radiotherapy: A Multi-Task Edge-Aware Learning.

More Whole Brain Radiotherapy sentence examples
10.21203/RS.3.RS-484218/V1

3%) were treated with whole-brain radiotherapy after FSRT owing to multiple intracranial recurrences, while surgery was performed for three patients (3.

Clinical Outcomes and Prognostic Factors of Fractionated Stereotactic Radiation Therapy for Large Brain Metastases as a Potential Alternative to Surgery

More Whole Brain Radiotherapy sentence examples
10.1007/s40278-021-00709-8

Due to the inability to tolerate rituximab and methotrexate chemotherapy, he underwent whole-brain radiotherapy on post-transplant day 280 for 47 days.

Methotrexate/rituximab/zanubrutinib

More Whole Brain Radiotherapy sentence examples
10.1007/s10549-020-06043-0

Initial whole-brain radiotherapy (WBRT) reduced new BM rates (22.

New brain metastases after whole-brain radiotherapy of initial brain metastases in breast cancer patients: the significance of molecular subtypes (KROG 16-12)

More Whole Brain Radiotherapy sentence examples
10.1007/s00330-020-07584-0

This study aimed to access the performance of apparent diffusion coefficient (ADC) as a predictor for treatment response to whole-brain radiotherapy (WBRT) in patients with brain metastases (BMs) from non-small-cell lung cancer (NSCLC).

Mean apparent diffusion coefficient in a single slice may predict tumor response to whole-brain radiation therapy in non-small-cell lung cancer patients with brain metastases

More Whole Brain Radiotherapy sentence examples
10.1007/s12094-021-02588-8

Nine patients were treated with upfront pembrolizumab alone, 8 patients with whole-brain radiotherapy (WBRT) followed by pembrolizumab and 13 patients with stereotactic radiosurgery (SRS) followed by pembrolizumab.

Upfront pembrolizumab as an effective treatment start in patients with PD-L1 ≥ 50% non-oncogene addicted non-small cell lung cancer and asymptomatic brain metastases: an exploratory analysis

More Whole Brain Radiotherapy sentence examples
10.2169/internalmedicine.7805-21

Objective Few reports have described the real-world outcomes of rituximab, methotrexate (MTX), procarbazine, and vincristine (R-MPV) plus response-adapted whole-brain radiotherapy (WBRT) for elderly patients with primary central nervous system lymphoma (PCNSL).

A Retrospective Analysis of R-MPV Plus Response-adapted Whole-brain Radiotherapy for Elderly Patients with Primary Central Nervous System Lymphoma.

More Whole Brain Radiotherapy sentence examples
10.7759/cureus.15212

The patient was therefore treated with an emergent course of whole-brain radiotherapy, resulting in immediate improvement and subsequent resolution of cranial neuropathies.

Emergent Radiotherapy for Leukemia-Induced Cranial Neuropathies Refractory to Intrathecal Therapy

More Whole Brain Radiotherapy sentence examples
10.1007/s00066-020-01739-0

Four weeks before the start of palliative whole-brain radiotherapy and bone irradiation of T12, she was administered a combination of docetaxel and ramucirumab.

Severe skin toxicity during whole-brain radiotherapy, targeted therapy, and additional drug intake including St. John’s wort skin oil

More Whole Brain Radiotherapy sentence examples
10.21203/RS.3.RS-144615/V1

Two randomized controlled trials (RCTs) were pooled to further evaluate the role of consolidation whole-brain radiotherapy (WBRT) in PCNSL.

Is It Time to Remove Radiotherapy in the Management of Primary Central Nervous System Lymphoma? Population-based Study, Pool-Analysis and Retrospective Study of Recurrence Pattern.

More Whole Brain Radiotherapy sentence examples
10.7150/jca.51411

There was a difference in OS of patients received the whole-brain radiotherapy (WBRT), stereotactic radiosurgery (SRS), or WBRT+SRS (20.

A real-world study in advanced non-small cell lung cancer with de novo brain metastasis

More Whole Brain Radiotherapy sentence examples
10.1016/j.radonc.2021.02.009

RESULTS After a median follow-up duration of 83 months (range, 20-214 months), 19 patients experienced relapse, including 15, 4, and 0 patients in the focal radiotherapy (FR) (n=35), whole-brain radiotherapy (WBRT) plus boost (n=109), and craniospinal irradiation (CSI) plus boost (n=17) groups, respectively.

Relapse pattern and quality of life in patients with localized basal ganglia germinoma receiving focal radiotherapy, whole-brain radiotherapy, or craniospinal irradiation.

More Whole Brain Radiotherapy sentence examples
10.1097/CAD.0000000000001199

Currently, it is mainly treated by whole-brain radiotherapy.

Pyrotinib treatment enhances the radiosensitivity in HER2-positive brain metastatic breast cancer patients.

More Whole Brain Radiotherapy sentence examples
10.5812/IJCM.111966

Patients with brain metastasis experienced cognition failure after whole-brain radiotherapy.

An Updated Review on Memantine Efficacy in Reducing Cognitive Dysfunction of Whole-brain Irradiation for Adult Patients with Brain metastasis

More Whole Brain Radiotherapy sentence examples
10.1097/CMR.0000000000000725

The patient was asymptomatic: she restarted targeted therapy and underwent evaluation for whole-brain radiotherapy.

A case of sudden brain metastases progression after temporary targeted therapy discontinuation: when to regret a drug holiday.

More Whole Brain Radiotherapy sentence examples
10.21037/JTD-2019-RBMLC-05

The possible treatment options for BM from lung cancer are whole-brain radiotherapy, stereotactic radiosurgery, surgery, chemotherapy, targeted therapies and best supportive care.

Management of brain metastases in elderly patients with lung cancer.

More Whole Brain Radiotherapy sentence examples
10.1016/j.ijrobp.2021.07.1556

For each patient, treatment plans (stereotactic radiosurgery [SRS] or whole-brain radiotherapy [WBRT]) were determined for both MRIs, with the gross target volume (GTV) indicating the contrast-enhancing aspects of the tumor.

Impact of the Novel Contrast Agent Gadopiclenol on Decision Making in Patients With Brain Metastases.

More Whole Brain Radiotherapy sentence examples
10.3389/fonc.2021.709188

In accordance with National Comprehensive Cancer Network guidance, the patient underwent whole-brain radiotherapy.

Case Report: Treatment of Alectinib in NSCLC With Brain Metastasis Patient Refractory to Radiotherapy After Resistance to Crizotinib

More Whole Brain Radiotherapy sentence examples
10.1017/S1460396921000030

To identify prognostic factors and investigate patient survival after whole-brain radiotherapy (WBRT) for initial brain metastases arising from non-small cell lung cancer (NSCLC).

Prognostic factors and survival after whole-brain radiotherapy for initial brain metastases arising from non-small cell lung cancer

More Whole Brain Radiotherapy sentence examples
10.3390/cancers13184711

In radio-oncological aspects, there also was a paradigm shift from whole-brain radiotherapy to localized radiotherapy including stereotactic radiosurgery.

Whole-Brain Radiotherapy vs. Localized Radiotherapy after Resection of Brain Metastases in the Era of Targeted Therapy: A Retrospective Study

More Whole Brain Radiotherapy sentence examples
10.1200/JCO.2021.39.15_SUPPL.9122

Kaplan-Meier (KM) modeling was used to evaluate for differences in overall survival (OS) between 3 cohorts of patients: those undergoing 1) stereotactic radiosurgery (SRS), 2) whole-brain radiotherapy (WBRT), and 3) those not undergoing brain radiotherapy (NR) as part of the first course of treatment.

Patterns of survival in NSCLC with de novo brain metastasis: SRS, WBRT, and no radiotherapy cohorts.

More Whole Brain Radiotherapy sentence examples
10.1080/0284186X.2021.1924399

Overall, studies report no difference in overall survival (OS) comparing SRT to whole-brain radiotherapy (WBRT).

Overall survival after initial radiotherapy for brain metastases; a population based study of 2140 patients with non-small cell lung cancer

More Whole Brain Radiotherapy sentence examples
10.1200/JCO.2021.39.15_SUPPL.E21096

e21096 MRI-based Radiomics signature for the Prediction of Response of Lung Cancer Brain Metastases After Whole-Brain Radiotherapy Background: Local response prediction for brain metastases (BMs) from lung cancer after Whole-Brain Radiotherapy (WBRT) is challenging, as existing criteria are based solely on unidimensional measurements.

MRI-based radiomics signature for the prediction of response of lung cancer brain metastases after whole-brain radiotherapy.

More Whole Brain Radiotherapy sentence examples
10.2147/CMAR.S304838

Related studies have preliminarily shown that anlotinib combined with whole-brain radiotherapy (WBRT) can significantly prolong the survival of patients with brain metastases of NSCLC.

Efficacy and Safety of Anlotinib in Patients with Advanced Non-Small Cell Lung Cancer: A Real-World Study

More Whole Brain Radiotherapy sentence examples
10.1186/s40364-021-00282-z

Commonly used regimens for PCNSL include high-dose methotrexate-based chemotherapy with rituximab for induction therapy and intensive chemotherapy followed by autologous hematopoietic stem cell transplantation or whole-brain radiotherapy for consolidation therapy.

Current and emerging therapies for primary central nervous system lymphoma

More Whole Brain Radiotherapy sentence examples
10.3389/fonc.2021.654727

For patients who received whole-brain radiotherapy (WBRT) and for those who did not (13 vs.

Clinicopathological Features and Prognoses in Patients With Brain Metastases From Small-Cell Esophageal Carcinoma: A Retrospective Analysis of 18 Patients

More Whole Brain Radiotherapy sentence examples
10.3390/cancers13020324

Inferior OS was observed in patients with ≥3 BMs and those who received whole-brain radiotherapy alone.

The Infratentorial Localization of Brain Metastases May Correlate with Specific Clinical Characteristics and Portend Worse Outcomes Based on Voxel-Wise Mapping

More Whole Brain Radiotherapy sentence examples
10.1200/JCO.21.00639

PURPOSE Radiation dose received by the neural stem cells of the hippocampus during whole-brain radiotherapy has been associated with neurocognitive decline.

Randomized Phase III Trial of Prophylactic Cranial Irradiation With or Without Hippocampal Avoidance for Small-Cell Lung Cancer (PREMER): A GICOR-GOECP-SEOR Study.

More Whole Brain Radiotherapy sentence examples
10.1097/MD.0000000000026911

As the patient could not tolerate further chemotherapy, he continued taking icotinib orally and received whole-brain radiotherapy 10 times to a total dose of 30 Gy after brain metastases.

Small-cell lung cancer transformation from EGFR-mutant adenocarcinoma after EGFR-TKIs resistance

More Whole Brain Radiotherapy sentence examples
10.1111/ajco.13624

PURPOSE To evaluate and investigate the feasibility of flattening filter-free (FFF) beam for the whole-brain radiotherapy (WBRT) with hippocampus sparing.

Comparison between flattening filter-free (FFF) and flattened photon beam VMAT plans for the whole brain radiotherapy (WBRT) with hippocampus sparing.

More Whole Brain Radiotherapy sentence examples
10.21037/jtd.2019.10.51

Owing to the different clinical and pathological characteristics of SCLC, patients with this histology were not included in the prospective studies on the value of whole-brain radiotherapy (WBRT) and local surgical or ablative radiation treatment like stereotactic radiosurgery (SRS).

Radiotherapy for brain metastases from small-cell lung cancer in distinct clinical indications and scenarios.

More Whole Brain Radiotherapy sentence examples
10.1007/s40278-021-93669-y

Thereafter, she underwent whole-brain radiotherapy (WBRT), which improved her daily activities.

Methotrexate/procarbazine/vincristine

More Whole Brain Radiotherapy sentence examples
10.1016/j.ijrobp.2021.05.125

Cranial radiotherapy (whole-brain radiotherapy [WBRT] or/and stereotactic radiosurgery [SRS]) performed before disease progression (PD) to osimertinib was categorized as upfront cranial radiotherapy (ucRT group), excluding those performed during prior EGFR-TKI treatment.

Clinical value of upfront cranial radiotherapy in osimertinib-treated EGFR-mutant non-small-cell lung cancer with brain metastases.

More Whole Brain Radiotherapy sentence examples
10.1097/CAD.0000000000000699

Intrathecal chemotherapy and whole-brain radiotherapy (WBRT), associated with a systemic treatment, are the most commonly used approach.

Four lines of anaplastic lymphoma kinase inhibitors and brain radiotherapy in a long-surviving non-small-cell lung cancer anaplastic lymphoma kinase-positive patient with leptomeningeal carcinomatosis

More Whole Brain Radiotherapy sentence examples
10.1007/978-3-030-00362-3_9

Whole-brain radiotherapy is no more routinely used at most centers due to increased risk of delayed CNS toxicity and the lack of overall survival prolongation after combined treatment.

Primary CNS Lymphoma

More Whole Brain Radiotherapy sentence examples
10.1093/jjco/hyz079

Ten patients received whole-brain radiotherapy (4 prophylactic, 6 therapeutic), and remaining one elderly patient underwent stereotactic radiosurgery.

Curative thoraco-systemic therapy plus local treatment to the brain for extensive disease-small-cell lung cancer with metastasis only to the brain.

More Whole Brain Radiotherapy sentence examples
10.21873/invivo.11459

Aim: This study aimed to identify prognostic factors for response to whole-brain radiotherapy (WBRT) in patients with brain metastases (BMs) from non-small cell lung cancer (NSCLC).

Neutrophil–to–Lymphocyte Ratio Predicts Survival After Whole-brain Radiotherapy in Non-small Cell Lung Cancer

More Whole Brain Radiotherapy sentence examples
10.1093/NOP/NPY038

Background This study evaluated the association between health-related quality of life (HRQOL) and cognition in patients receiving memantine for prevention of cognitive dysfunction during whole-brain radiotherapy (WBRT).

The association of health-related quality of life and cognitive function in patients receiving memantine for the prevention of cognitive dysfunction during whole-brain radiotherapy.

More Whole Brain Radiotherapy sentence examples
10.20517/2394-4722.2018.114

Whole-brain radiotherapy (WBRT) is the standard treatment of BM from SCLC.

Radiotherapy of brain metastases from small-cell lung cancer: standards and controversies

More Whole Brain Radiotherapy sentence examples
10.12890/2019_001337

We report the case of a 36-year-old Caucasian female with a history of craniopharyngioma treated with whole-brain radiotherapy 20 years previously.

Moyamoya Syndrome after Radiation Therapy: a Clinical Report

More Whole Brain Radiotherapy sentence examples
10.3892/MCO.2019.1820

Treatment, including whole-brain radiotherapy, was planned for MC; however, the patient's condition rapidly worsened and he succumbed to the disease 14 days after the diagnosis of MC.

Meningeal carcinomatosis from bladder cancer: A case report and review of the literature.

More Whole Brain Radiotherapy sentence examples
10.21873/anticanres.13247

Background/Aim: The interval between diagnostic imaging and whole-brain radiotherapy (WBRT) had no significant impact on survival in our previous study of WBRT for brain metastases.

Potential Impact of the Interval Between Imaging and Whole-brain Radiotherapy in Patients With Relatively Favorable Survival Prognoses

More Whole Brain Radiotherapy sentence examples
10.1159/000504933

He underwent whole-brain radiotherapy (WBRT) concurrently with 2 cycles of BEP, leading to successful reduction of brain metastases.

Multimodal Treatment of Extragonadal Choriocarcinoma with Multiple Brain and Lung Metastases: A Case Report

More Whole Brain Radiotherapy sentence examples
10.4103/ojo.OJO_68_2016

Radiation maculopathy, a subset of significant radiation retinopathy, is one of the most common causes of visual loss following localized, regional, or whole-brain radiotherapy.

Effect of intravitreal dexamethasone implant on the contralateral eye in recalcitrant radiation maculopathy

More Whole Brain Radiotherapy sentence examples
10.24875/J.GAMO.M18000145

Results: The most frequent finding was breast cancer Her2/Neu biotype, 83% of the patients with supratentorial location, 33% of patients had received previously whole-brain radiotherapy, and 60% had > 5 cc tumoral volume.

Radioinduced effects in patients with brain metastases treated with CyberKnife® platform radiosurgery

Learn more from Whole Brain Radiotherapy

Keywords related to Whole

Keywords related to Radiotherapy

Whole Brain Radiotherapy
Encyclopedia

What is/are Whole Brain Radiotherapy?

Whole Brain Radiotherapy - Patients and Methods: This was a retrospective single-institution analysis of 249 patients, managed with whole-brain radiotherapy for brain metastases. [1] • A history of whole-brain radiotherapy did not increase the risk. [2] Studies that assessed cognitive functions systematically months to years after HD-MTXbased chemotherapy and consolidation whole-brain radiotherapy (WBRT) reported cognitive impairment and white matter abnormalities in most patients. [3] After 3 relapses and intensive treatment with multiple chemotherapy regimens and whole-brain radiotherapy, she received off-label treatment with the Bruton tyrosine kinase inhibitor ibrutinib, responded well, achieved a complete remission, and is progression-free for now >3 years. [4] Protection of the hippocampus during whole-brain radiotherapy reduces therapy toxicity. [5] Then, the patient received 10 cycles of chemotherapy with high-dose methotrexate (HD-MTX) and whole-brain radiotherapy. [6] After 3 cycles of MPV (methotrexate, procarbazine, vincristine) followed by whole-brain radiotherapy, her cognitive impairment improved. [7] Potential options include high-dose therapy with haematopoietic stem cell consolidation, non-myeloablative chemotherapy and whole-brain radiotherapy. [8] Where possible, a comparison with whole-brain radiotherapy (WBRT) was performed. [9] Potential consolidation treatment options include high-dose therapy with stem cell consolidation, non-myeloablative chemotherapy, or whole-brain radiotherapy (WBRT) but the increased risk of delayed neurotoxicity associated with the latter means this is utilized less frequently. [10] The present study aimed to assess the value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in predicting the treatment outcomes of whole-brain radiotherapy (WBRT) and gefitinib in brain metastases from non-small cell lung cancer (NSCLC) from the perspectives of response rate and short- and long-term efficacy. [11] Patient concerns: We present a case of a 55-year-old male patient suffering from brain metastases, who had previously received whole-brain radiotherapy (WBRT) and first CyberKnife Stereotactic Radiotherapy (CKSRT) for metastases, presented with a recurrence of metastasis and new lesions in the brain. [12] Methods This was a single-center, retrospective cohort study of consecutive newly diagnosed immunocompetent PCNSL patients treated with HD-MTX (5 cycles of 3 g/m2 every 2 weeks) followed by consolidation whole-brain radiotherapy (WBRT) and cytarabine (2 cycles of 3 g/m2/d for 2 days every 3 weeks) from January 2013 to December 2020. [13] Propensity score matching (PSM) was used to evaluate survival according to RT modality, which included whole-brain radiotherapy (WBRT) and/or stereotactic radiosurgery (SRS). [14] We performed a retrospective, multi-centre analysis of 14 patients with pCNS-PTLD after solid organ transplantation (SOT) treated in the prospective German PTLD registry with reduction of immunosuppression (RI), whole-brain radiotherapy (WBRT), and concurrent systemic rituximab between 2001 and 2018. [15] LT comprised stereotactic (SRT; n = 40; 34%) or whole-brain radiotherapy (WBRT; n = 77; 66%), while neurosurgical resection was carried out in 19 cases. [16] Moreover, these drugs may delay the use of local therapies, such as stereotactic radiosurgery (SRS) or whole-brain radiotherapy (WBRT). [17] Pharmacological depletion of microglia during whole-brain radiotherapy prevents synaptic loss and long-term recognition memory deficits. [18] This review explores the impact of whole-brain radiotherapy (WBRT) or stereotactic radiosurgery (SRS) on cognition. [19] Progression after front-line chemotherapy is common, and whole-brain radiotherapy (WBRT) is a standard salvage treatment as there is a concern that localized treatment fields would not prevent out-of-field recurrences. [20] 6%), whole-brain radiotherapy (2 patients, 2. [21] Traditionally, due to the limited efficacy of cytotoxic chemotherapy, treatment strategies are focused on local treatments alone, such as whole-brain radiotherapy (WBRT), stereotactic radiosurgery (SRS), and resection. [22] Postoperative therapy consisted of whole-brain radiotherapy in 4 cases and molecular targeted therapy in 4, with 6 patients not receiving any postoperative treatment. [23] , after whole-brain radiotherapy. [24] Purpose: The aim of this study is to comparatively examine the possibility of reducing the exposure dose to organs at risk, such as the hippocampus and lens, and improving the dose distribution of the planned target volume with and without the use of a head-tilting base plate in hippocampal-sparing whole-brain radiotherapy using tomotherapy. [25] To optimize the collimator angles in dual-arc volumetric modulated arc therapy (VMAT) plans for whole-brain radiotherapy with hippocampus and inner ear sparing (HIS-WBRT). [26] On the other hand, with respect to radiotherapy dose, among older patient group, greater hypofractionation and whole-brain radiotherapy was applied (P = 0. [27] The metastatic lesions in the body regressed, but the brain metastasis progressed and was treated with whole-brain radiotherapy and concomitant temozolomide. [28] He had previously received paclitaxel/carboplatin, gemcitabin/ vinorelbine chemotherapy, stereotactic radiosurgery for brain metastasis, and whole-brain radiotherapy as treatment for NSCLC. [29] Protection of the hippocampus during whole-brain radiotherapy reduces therapy toxicity. [30] The therapeutic regimen then consisted of whole-brain radiotherapy, anti-angiogenesis therapy, and immunotherapy. [31] Intrathecal chemotherapy (ITC), whole-brain radiotherapy (WBRT) with a simultaneous integrated boost (SIB) followed by Osimertinib was initiated. [32] HAART was initiated with whole-brain radiotherapy (WBRT), and the patient declined systemic chemotherapy. [33] The craniocerebral lesions attained partial remission after whole-brain radiotherapy and targeted combined immunotherapy, and other distant metastases completely disappeared after targeted combined immunotherapy (anlotinib and camrelizumab), indicating significant treatment efficacy. [34] INTRODUCTION The historical standard of care for brain metastases (BMs) from small cell lung cancer (SCLC) has been whole-brain radiotherapy (WBRT). [35] Treatments including systemic therapy, whole-brain radiotherapy (WBRT), stereotactic radiosurgery (SRS), and intrathecal chemotherapy with Methotrexate (IT MTX) were recorded. [36] Whole-brain radiotherapy (WBRT) is the mainstay of therapy in treating cancer patients with brain metastases, but unfortunately, it might also lead to decline in neurocognitive function. [37] OBJECTIVE This study aimed to evaluate the safety, efficacy, and feasibility of the rituximab, fotemustine, pemetrexed, and dexamethasone (R-FPD) regimen followed by whole-brain radiotherapy (WBRT) for patients with primary central nervous system lymphoma (PCNSL). [38] Objectives: Hippocampus-sparing whole-brain radiotherapy (HS-WBRT) using tomotherapy is known to provide a better dose distribution than volumetric-modulated arc therapy but requires an extended irradiation time. [39] He had undergone whole-brain radiotherapy with a total dose of 30 Gy over 10 fractions and concurrent chemotherapy with cisplatin and pemetrexed. [40] He received whole-brain radiotherapy followed by the administration of pembrolizumab. [41] She underwent whole-brain radiotherapy followed by immunotherapy. [42] Whole-brain radiotherapy (WBRT) is one of the standard treatment strategies for NSCLC. [43] 52% received whole-brain radiotherapy. [44] PURPOSE/OBJECTIVE(S) Local response prediction for brain metastases (BMs) from lung cancer after Whole-Brain Radiotherapy (WBRT) is challenging, as existing criteria are based solely on unidimensional measurements. [45] This was a single-center, retrospective cohort study of consecutive newly diagnosed immunocompetent PCNSL patients treated with HD-MTX (5 cycles of 3 g/m2 every 2 weeks) followed by consolidation whole-brain radiotherapy (WBRT) and cytarabine (2 cycles of 3 g/m2/d for 2 days every 3 weeks) from January 2013 to December 2020. [46] OBJECTIVE The aim of the present work was to investigate the response and safety of whole-brain radiotherapy (WBRT) plus temozolomide (TMZ) for patients with brain metastases of non-small-cell lung cancer (NSCLC). [47] CONCLUSION Our results demonstrated the efficiency of multi-task edge-aware learning in hippocampus segmentation for hippocampal sparing whole-brain radiotherapy. [48] 3%) were treated with whole-brain radiotherapy after FSRT owing to multiple intracranial recurrences, while surgery was performed for three patients (3. [49] Due to the inability to tolerate rituximab and methotrexate chemotherapy, he underwent whole-brain radiotherapy on post-transplant day 280 for 47 days. [50]

non small cell

The present study aimed to assess the value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in predicting the treatment outcomes of whole-brain radiotherapy (WBRT) and gefitinib in brain metastases from non-small cell lung cancer (NSCLC) from the perspectives of response rate and short- and long-term efficacy. [1] OBJECTIVE The aim of the present work was to investigate the response and safety of whole-brain radiotherapy (WBRT) plus temozolomide (TMZ) for patients with brain metastases of non-small-cell lung cancer (NSCLC). [2] This study aimed to access the performance of apparent diffusion coefficient (ADC) as a predictor for treatment response to whole-brain radiotherapy (WBRT) in patients with brain metastases (BMs) from non-small-cell lung cancer (NSCLC). [3] To identify prognostic factors and investigate patient survival after whole-brain radiotherapy (WBRT) for initial brain metastases arising from non-small cell lung cancer (NSCLC). [4] Aim: This study aimed to identify prognostic factors for response to whole-brain radiotherapy (WBRT) in patients with brain metastases (BMs) from non-small cell lung cancer (NSCLC). [5] Purpose: To compare the differences in survival and intracranial local control between patients treated with whole-brain radiotherapy (WBRT) and WBRT plus a radiotherapy boost (RTB) in non-small-cell lung cancer (NSCLC) patients with brain metastases (BMs). [6]

include high dose

Potential options include high-dose therapy with haematopoietic stem cell consolidation, non-myeloablative chemotherapy and whole-brain radiotherapy. [1] Potential consolidation treatment options include high-dose therapy with stem cell consolidation, non-myeloablative chemotherapy, or whole-brain radiotherapy (WBRT) but the increased risk of delayed neurotoxicity associated with the latter means this is utilized less frequently. [2] Commonly used regimens for PCNSL include high-dose methotrexate-based chemotherapy with rituximab for induction therapy and intensive chemotherapy followed by autologous hematopoietic stem cell transplantation or whole-brain radiotherapy for consolidation therapy. [3]

small cell lung

INTRODUCTION The historical standard of care for brain metastases (BMs) from small cell lung cancer (SCLC) has been whole-brain radiotherapy (WBRT). [1] Diagnosis-specific survival scores including a new score developed in 157 patients with brain metastases from small-cell lung cancer (SCLC) receiving whole-brain radiotherapy (WBRT) with 30 Gy in 10 fractions (WBRT-30-SCLC) were compared. [2]

3 g m2

Methods This was a single-center, retrospective cohort study of consecutive newly diagnosed immunocompetent PCNSL patients treated with HD-MTX (5 cycles of 3 g/m2 every 2 weeks) followed by consolidation whole-brain radiotherapy (WBRT) and cytarabine (2 cycles of 3 g/m2/d for 2 days every 3 weeks) from January 2013 to December 2020. [1] This was a single-center, retrospective cohort study of consecutive newly diagnosed immunocompetent PCNSL patients treated with HD-MTX (5 cycles of 3 g/m2 every 2 weeks) followed by consolidation whole-brain radiotherapy (WBRT) and cytarabine (2 cycles of 3 g/m2/d for 2 days every 3 weeks) from January 2013 to December 2020. [2]