Introduction to Vulvar Cancer
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Vulvar Cancer sentence examples within sentinel lymph node
PURPOSE/OBJECTIVE(S)
Inguinofemoral lymphadenectomy (IFL) is a morbid procedure, and studies support the use of sentinel lymph node biopsy (SLNB) as an initial staging procedure for women with early stage operable vulvar cancer.
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Sentinel lymph node (SN) biopsy is essential for evaluating survival and minimal treatment-related morbidity associated with cervical, endometrial, and vulvar cancer in Japan.
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Vulvar Cancer sentence examples within squamous cell carcinoma
Vulvar cancer accounts for 2% to 5% of all gynecological cancers worldwide, among which squamous cell carcinoma is the most common followed by melanoma.
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Superficially, invasive vulvar squamous cell carcinoma (SISCCA) (FIGO stage IA) is a rare subset of vulvar cancer defined as a single lesion measuring ≤2 cm with a depth of invasion of ≤1.
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Vulvar Cancer sentence examples within cancer cervical cancer
Common gynecological malignancies include endometrial cancer, cervical cancer, ovarian cancer, and vulvar cancer.
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Main objective was to perform a systematic review of relative publications concerning sexual dysfunction parameters in gynaecological cancer patients, namely endometrial cancer, ovarian cancer, cervical cancer and vulvar cancer.
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Vulvar Cancer sentence examples within Background Vulvar Cancer
Background Vulvar cancer is a rare disease and despite broad adoption of sentinel lymph node mapping to assess groin metastases, inguino-femoral lymph node dissection still plays a role in the management of this disease.
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Background Vulvar cancer is becoming more common in young women owing to the increased prevalence of co-infection with human papillomavirus and HIV.
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Vulvar Cancer sentence examples within Recurrent Vulvar Cancer
OBJECTIVE
Summarizing of treatment options for locally recurrent vulvar cancer in patients after previous complex oncological treatment and presenting a case report from our department.
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IRT as part of primary treatment for primary and/or recurrent vulvar cancer is associated with promising clinical outcomes.
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Vulvar Cancer sentence examples within Stage Vulvar Cancer
The FDG pattern resembled as a cIV stage vulvar cancer, whereas biopsy indicated metastases from breast cancer.
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Introduction/Background To evaluate the effectiveness and limitations of Technetium-99m for lymphoscintigraphic mapping and sentinel lymph nodes (SLNs) localization in early stage vulvar cancer patients.
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Vulvar Cancer sentence examples within Advanced Vulvar Cancer
OBJECTIVE
To evaluate feasibility of chemoradiation as alternative for extensive surgery in patients with locally advanced vulvar cancer and to report on locoregional control, toxicity and survival.
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The article discusses the choice of different surgical procedures in patients with locally advanced vulvar cancer, depending on the volume of resected tissues and the possibility of reconstructive plastic surgery.
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Vulvar Cancer sentence examples within Squamou Vulvar Cancer
Vulvar Cancer sentence examples within Positive Vulvar Cancer
Moderate antitumor activity of pembrolizumab (ORR, 6%) was noted in a small population of patients (pts) with PD-L1-positive vulvar cancer in the phase 1b KEYNOTE-028 study.
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PURPOSE/OBJECTIVE(S)
Prior studies have demonstrated a survival benefit with the addition of adjuvant radiation therapy in patients with node-positive vulvar cancer after surgery.
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Vulvar Cancer sentence examples within vulvar cancer patient
This retrospective study aimed to assess the diagnostic performance of preoperative [18F]FDG-PET/CT in predicting the groin and pelvic lymph node (LN) status in a large single-centre series of vulvar cancer patients.
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[1] published in this issue of the EJNMMI is the largest series of vulvar cancer patients preoperatively staged with [F]FDG-PET/CT.
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Vulvar Cancer sentence examples within vulvar cancer treated
6% of PS patients were stage I (p Download : Download high-res image (93KB) Download : Download full-size image Conclusions: Women with vulvar cancer treated with PRT at a large, managed care organization over a 10-year period were higher stage and had worse 1- and 3-year overall survival than women treated with PS, although survival was not significantly different when adjusting for stage.
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Here, we analyze patterns of recurrence in patients with vulvar cancer treated with radiotherapy according to original planning target volumes and radiation dose delivered.
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Vulvar Cancer sentence examples within vulvar cancer represent
Vulvar Cancer sentence examples within vulvar cancer case
Vulvar Cancer sentence examples within vulvar cancer account
Materials and methods Rectal swabs from 58 women with cervical, vaginal, or vulvar cancer from two institutions were prospectively analyzed before CRT (baseline), during CRT (weeks 1, 3, and 5), and at first follow-up (week 12) using 16Sv4 rRNA gene sequencing of the V4 hypervariable region of the bacterial 16S rRNA marker gene.
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Simple Summary A multicenter prospective observational study was conducted on patients with vulvar cancer (VC) refractory or not amenable to standard therapies undergoing palliative electrochemotherapy (ECT) as per clinical practice.
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• Our findings pose a challenge to the two-pathway model in vulvar cancer development.
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This review article summarizes the clinical applications of established and emerging PET tracers in the evaluation of the 5 most common gynecologic malignancies: endometrial, ovarian, cervical, vaginal, and vulvar cancers.
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Patients affected by vulvar cancer or either with tumor size >5 cm, positive lymph nodes, LVI have worse oncologic outcomes.
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Although it is yet an experimental approach in ovarian cancer, it has been incorporated into guidelines for endometrial, cervical and vulvar cancers.
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AIMS
Radio(chemo)therapy plays an important role in the treatment of vulvar cancer, either as postoperative treatment or as definitive treatment in patients who present with inoperable disease.
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The base-case lifetime cost per patient for different stages of vulvar cancer/penile cancer/anal cancer/oral cancer/oropharyngeal cancer/laryngeal cancer falls within $17,120–$58,236.
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ASAH1 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
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CONCLUSIONS
SLNB accurately detects lymph node metastases in high-grade EC, with a false negative rate comparable to that observed in low-grade EC, melanoma, vulvar cancer, and breast cancer.
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COL14A1 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
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Human papilloma virus (HPV) is the primary causative agent of cervical, vaginal, and vulvar cancers.
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NRN1 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
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This retrospective study aimed to assess the diagnostic performance of preoperative [18F]FDG-PET/CT in predicting the groin and pelvic lymph node (LN) status in a large single-centre series of vulvar cancer patients.
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SVEP1 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
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SCUBE2 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
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NPDC1 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
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Future research will focus on establishing sensitivity and specificity of this tool and further assessing its utility in clinical settings for all gynaecological cancers (including rare cancers like vulvar cancer).
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There are a limited number of reports of vulvar cancer cases younger than 30 years.
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In centers with access to high‐end ultrasound machines and expert sonologists, ultrasound is used to detect metastases in regional lymph nodes from melanoma, breast cancer and vulvar cancer.
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Vulvar cancer is rare and accounts for only 5% of all gynecologic cancers.
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Human papillomavirus (HPV) infection drives tumorigenesis in the majority of cervical, oropharyngeal, anal, and vulvar cancers.
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PID1 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
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AOC3 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
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Vulvar cancer was the most common primary diagnosis (32%); 30% had cervical cancer; 23%, uterine cancer; 15%, vaginal cancer.
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SUMMARY The aim of this retrospective study was to show the effect of clinical, pathologic, cytologic and therapeutic prognostic factors on treatment outcome and survival of patients suffering from vulvar cancer and to determine prognostic significance of each of the individual factors, their mutual significance and impact on survival.
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5593 Background: Although well established in cervical cancer, it is unclear whether time from initiation to completion of radiation therapy for vulvar cancer affects survival outcomes.
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e15502 Background: HPV status of anal and vulvar cancers cannot be predicted by visual inspection as well as for oropharyngeal cancers.
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Vulvar cancer incidence numbers have been rising steadily over the past decades.
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Evidence Acquisition A literature search was conducted, focusing on the plastic surgery and gynecologic oncology literature, using the following search terms: “vulvar reconstruction,” “perineal reconstruction,” “vulvectomy,” and “vulvar cancer.
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DCLK1 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
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SLIT2 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
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Vulvar cancer is a disease with a well-defined natural history; but with the advancement of therapeutic possibilities in recent years, it has been possible to improve the prognosis, reducing the chance of locoregional recurrence.
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In total, 31 patients had cervical cancer, 76 patients had endometrial cancer, 52 patients had ovarian or tubal cancer, 5 patients had a borderline tumor of the ovary, and 17 patients had vulvar cancer.
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ECT in association with bleomycin is an effective and safe treatment option in the vulvar cancer palliative setting.
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Primary surgical management is successful as the sole therapeutic modality in the majority of women with early-stage cervical, vaginal and vulvar cancer, but the presence of certain risk factors in the surgico-pathological specimen indicates a poorer prognosis.
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Methods: We included women ≥ 66 years with stage III-IV, ovarian, uterine, cervix or vulvar cancer diagnosed in 2011 and 2013 in the linked Surveillance Epidemiology, End Results (SEER)- Medicare database.
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