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A 27-year-old man developed multiple itchy reddish, elevated lesions following one after the second dose of COVID-19 vaccine (whole virion inactivated coronavirus vaccine).
We report the development and evaluation of safety and immunogenicity of a whole virion inactivated (WVI) SARS-CoV-2 vaccine (BBV152), adjuvanted with aluminium hydroxide gel (Algel), or TLR7/8 agonist chemisorbed Algel.
These cohorts received either ChAdOx nCOV-19 (Recombinant) or the whole virion inactivated Vero cell vaccines.
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With the advent of SARSCoV2 vaccines viz, mRNA, recombinant adenovirus vector and whole virion inactivated vero cell, which are inactivated vaccines having emergency use authorisation granted by the US Food and Drug Administration on 11 December 2020, led to a ray of hope in the COVID19 pandemic.
Subsequently, a whole virion inactivated candidate vaccine, QazCovid-in, was developed based on this virus.
Covaxin/BBV152 is a whole virion inactivated SARS-CoV-2 vaccine.
Background: We report the clinical efficacy against COVID 19 infection of BBV152, a whole virion inactivated SARS CoV 2 vaccine formulated with a Toll like receptor 7/8 agonist molecule adsorbed to alum (Algel IMDG).
Subsequently, a whole virion inactivated candidate vaccine, QazCovid-in, was developed based on this virus.
PVI was investigated after recombinant ChAdOx nCOV-19 (Recombinant) or the whole virion inactivated Vero cell vaccines were administered.