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These two peptides are shown to have diverse functions, including the regulation of inflammation and bone formation, among others.
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These two peptides were identified in fermented and enzymatic hydrolyzed cow and non-cow (that is, goat, sheep, buffalo, yak, camel, mare, and donkey) milk, as well as sourdough prepared from wheat, rye, and malt.
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We identified two peptides of “VLPVPQK” and “AVPYPQR” as substrates for both of the TGases.
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We identified two peptides and 15 small molecules (putatively targeting the disulfide bridge) as candidate CD98hc inhibitors by phage display and in silico screenings, respectively, and validated in vitro the binding between peptides and transmembrane fraction of CD98hc by cytofluorimetric assay.
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To study functional roles and action mechanisms of peptides containing cholesterol-recognizing amino-acid consensus (CRAC) motifs, we designed and synthesized peptide RTKLWEMLVELGNMDKAVKLWRKLKR (peptide P4), which includes two peptides corresponding to CRAC-containing α-helices 3 and 6 of influenza virus protein M1 (LEVLMEWLKTR, aa 39–49, and NNMDKAVKLYRKLK, aa 91–105, respectively).
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This study aimed to evaluate the abilities of two peptides derived from egg albumin transferrin, IRW and IQW, to treat enteritis in a mouse model of Citrobacter rodentium-induced colitis by evaluating serum metabolomics and gut microbes.
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The two peptides derived from fibrils are β-amyloid and α- synuclein, which form plaques in the brain.
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Two Peptides sentence examples within two peptides individually
These effects were particularly pronounced for the so-called synergistic mixture of 1:1 (mol/mol) L18W-PGLa/MG2a and cannot be accounted for by a linear combination of the membrane perturbations of two peptides individually.
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These effects were particularly pronounced for the so called synergistic mixture of 1:1 (mol/mol) L18W-PGLa/MG2a and cannot be accounted for by a linear combination of the membrane perturbations of two peptides individually.
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Additionally, thirty-two peptides containing 59 Hyp residues and a few G-X-Y triplets with positional alterations of Hyp in COLIIA1 are also identified.
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Additionally, thirty-two peptides containing 59 Hyp residues and a few G-X-Y triplets with positional alterations of Hyp in COLIIA1 are also identified.
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Two Peptides sentence examples within two peptides showed
In addition, the two peptides showed similar anti-inflammatory activity against in lipopolysaccharide-stimulated RAW 264.
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These two peptides showed opposite effects, and subsequently a comparative proteomic analysis characterized 64 differentially expressed membrane proteins from the JZTX‐I‐ and HNTX‐III‐treated groups.
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In addition, the two peptides could effectively control green mold on citrus in vivo study.
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This analysis revealed two peptides (SIR16-D1 and SIR16-H1) from the local isolates with good accuracy for the detection of acute leptospirosis (area under the ROC curve: 0.
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Investigating the structural origin of these synergistic antimicrobial effects with NMR spectroscopy of the complex formed between these two peptides and their mutated analogs, we demonstrate the formation of an unusual peptide complex, characterized by the formation of a bulky hydrophobic hub, stabilized by aromatic zippers.
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Two peptides, KELPPSDADW and SSDEEVREEKELDLSSNE of the pepsin hydrolysates, three peptides, TVGGAPAGRIVME, VGGIDEVIAK and GNPIPREPGQVPAY of the Alcalase hydrolysates, and two peptides SGGSYADELVSTAK and MDATALHYENQK of the proteinase K hydrolysates were identified as the main components.
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The optimal length, as well as the corresponding most likely HLA-restriction, of each of these two peptides was assessed.
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The hydrogels formed by different mixtures of the two peptides are made up mainly of antiparallel β‐sheet nanofibers entangling in an intricate network.
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Two peptides TVGMTAKF and QLLLQQ exhibited the highest ACE inhibitory activity (IC50 values of 30.
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For this reason, two peptides P1 (NH2-C-G-G-W-R-S-Q-N-Q-G-NH2) and P2 (NH2-C-G-G-R-R-Y-Q-P-D-S-NH2) binding with the CB dye were synthesized by the solid-phase peptide synthesis (SPPS) technique.
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Furthermore, tripartite applications have been produced from both systems allowing the fusion of two peptides by a separate, catalytically active protein unit, SpyLigase or SnoopLigase.
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To this end, we grafted two peptides, harboring important epitopes of the hepatitis B virus (HBV) S antigen and human papilloma virus (HPV) L2 protein, onto OmpF of E.
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This study aimed to evaluate the abilities of two peptides derived from egg albumin transferrin, IRW and IQW, to treat enteritis in a mouse model of Citrobacter rodentium-induced colitis by evaluating serum metabolomics and gut microbes.
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These two peptides are shown to have diverse functions, including the regulation of inflammation and bone formation, among others.
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Two peptides were selected based on performance characteristics: ANQAFLPASTFK, a core peptide common to all 12 OXA-48 family β-lactamase members, and YSVVPVYQEFAR, a highly specific peptide common to 11 of 12 OXA-48 family proteins providing the basis for an LC-MS/MS multiple reaction monitoring assay.
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These effects were particularly pronounced for the so-called synergistic mixture of 1:1 (mol/mol) L18W-PGLa/MG2a and cannot be accounted for by a linear combination of the membrane perturbations of two peptides individually.
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Based on pharmacophore model, two peptides were generated by specific amino acids substitutions of the parental NCR peptides; these new peptides resumed the common chemical features of CR peptides and bound the CLL BCR clonotypes recognized by CR peptides and parental NCR peptides.
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Plantaricin JK (PlnJK) is a Class IIb LAB bacteriocin that includes two peptides; i.
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Two peptides RALP and WYT were reported to possess antihypertensive activity targeting both renin and ACE, and we have used molecular docking and molecular dynamics simulation, in order to understand the underlying mechanism.
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Finally, two peptides (Leu-Val-Gly-Arg-Pro-Arg-His-Gly-Gln and Val-Phe-Pro-Ser) were identified in the E2-treated hydrolysate using UPLC-QTOF-MS/MS.
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Regardless of the moieties fused to K3 and E3, these two peptides self-assembled into dimers of dimers to form bivalent heterotetrameric complexes that proved to be extremely stable inside living cells.
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Two peptides were included, one acetylated at a lysine (anti-AcLys) and the other at an ornithine (anti-AcOrn) and considered either individually or combined.
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They were able to reduce phospholipase activity and peptides DFCHNV and ATHEE reached the highest reduction levels, being these two peptides the best that also interacted in the in silico experiments.
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Two peptides were identified as DHG-specific peptides.
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Fusion of these two peptides to MAP30 peptide substantially reduced the IC50 of ZIKV protease inhibition to 1.
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Ionic blockades through engineered nanopores distinguish a variety of peptides, including two peptides differing only by the substitution of alanine with glutamate.
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Two peptides (16433 and 4934) in the nsp3 region encoding the papain 1 and 2 proteases were identified for final testing.
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Two peptides inhibitors of PINK1 mitigated the mitochondrial defects introduced by CHCHD10S59L expression.
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Molecular dynamics simulation and binding energetics decomposition reveal that the two peptides possess large flexibility and intrinsic disorder in unbound free state, and thus would incur a considerable entropy penalty upon binding to Keap1.
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Finally, from the potential of mean force (PMFs) calculations, we observe that the free energy between two peptides is more negative in the absence of COS and with increasing concentration of COS, it becomes unfavorable significantly indicating that the peptide dimer formation is most stable in pure water, which becomes less favorable in the presence of COS.
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Here we report the modification of two peptides that comprise a coiled-coil heterodimer pair with unique DNA handles in order to link DNA origami nanostructures bear-ing complementary strands into micrometer-long one-dimensional arrays.
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Fifty‐two peptides encoded by CLE genes were identified in the genome of Populus trichocarpa.
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To study functional roles and action mechanisms of peptides containing cholesterol-recognizing amino-acid consensus (CRAC) motifs, we designed and synthesized peptide RTKLWEMLVELGNMDKAVKLWRKLKR (peptide P4), which includes two peptides corresponding to CRAC-containing α-helices 3 and 6 of influenza virus protein M1 (LEVLMEWLKTR, aa 39–49, and NNMDKAVKLYRKLK, aa 91–105, respectively).
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Here, we provide a proof of concept demonstration by designing and synthesizing two peptides, AR5 and AR6, that combine a peptide fragment derived from two viral ligands of CXCR4, vMIP-II and HIV-1 envelope glycoprotein gp120.
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Moreover, its combination with either of these two peptides also presents excellent effect on cell migration.
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The two peptides derived from fibrils are β-amyloid and α- synuclein, which form plaques in the brain.
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These two peptides were identified in fermented and enzymatic hydrolyzed cow and non-cow (that is, goat, sheep, buffalo, yak, camel, mare, and donkey) milk, as well as sourdough prepared from wheat, rye, and malt.
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Soy1 (IAVPTGVA) and Lup1 (LTFPGSAED), two peptides from soybean and lupin protein hydrolysis, have been singled out as dipeptidyl peptidase IV (DPP-IV) activity inhibitors in different model systems.
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Two peptides exhibited different ACE-inhibitory activities; however, the molecular mechanism involved is poorly understood.
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Other two peptides, LGIGTVLDQAETAG and VLVLNPSVAATLGF, taken from NS3 protein were selected as CD4+ T cell inducer.
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These two peptides may be potential biomarkers for schizophrenia in the Chinese population.
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We found that two peptides could elicit ROS production in Arabidopsis and Nicotiana benthamiana.
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We mapped two peptides in the DBL5ε domain of VAR2CSA that are recognized by SD1 antibodies.
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Our results show that both AD#1 peptide and Con#1 peptide could distinguish AD/MCI patients from controls and combination of these two peptides could greatly improve the diagnostic performance (AUC is above 0.
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Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are two peptides that function to promote insulin secretion.
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Methods and materials In this study, we constructed nanoparticles (NPs) using polydopamine to carry two peptides that simultaneously bind integrin αIIbβ3 and P-selectin on activated platelets to enhance the targeting of NPs to thrombus.
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To analyze expression of the NDV W protein, two peptides encompassing predicted antigenic sites of the unique C-terminal W protein amino acid sequence of NDV Clone 30 were used for the generation of W-specific rabbit antisera.
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In particular, 5 peptides of γ-gliadin, known to trigger the adaptive immune reaction, and two peptides of α-gliadin, known to be toxic to celiac patients, were particularly abundant in some old varieties.
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Indeed, these two peptides present two cooperative modes of action that should prevent the conformational change at the origin of the spring-loaded mechanism at pH = 5, (1) mechanical because they are docked on HA2 and (2) electronic because they modify the protonation states of key residues in the loop.
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Incretin contains two peptides named glucagon-like peptide-1and glucose-dependent insulinotropic polypeptide.
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