Introduction to Trials Unit

Sentence Examples

Discover more insights into Trials Unit

Keywords frequently search together with Trials Unit

Narrow sentence examples with built-in keyword filters

Trials Unit sentence examples within Clinical Trials Unit

Clinical Trials Unit

Tran: Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self), Research grant / Funding (institution), Travel / Accommodation / Expenses: Amgen; Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self), Travel / Accommodation / Expenses: Astellas; Honoraria (self), Advisory / Consultancy, Research grant / Funding (self), Travel / Accommodation / Expenses: Bayer; Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self): BMS; Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self), Research grant / Funding (institution), Non-remunerated activity/ies: Janssen-Cilag; Honoraria (self), Advisory / Consultancy, Research grant / Funding (institution): MSD; Honoraria (self), Advisory / Consultancy, Research grant / Funding (institution): Novartis; Honoraria (self), Advisory / Consultancy, Travel / Accommodation / Expenses: Sanofi; Honoraria (self), Advisory / Consultancy: Tolmar; Honoraria (self), Advisory / Consultancy, Research grant / Funding (self): Ipsen; Research grant / Funding (self), Research grant / Funding (institution): AstraZeneca; Research grant / Funding (self): Pfizer; Research grant / Funding (self), Research grant / Funding (institution): Servier; Research grant / Funding (institution): Aslan; Research grant / Funding (institution): GSK; Research grant / Funding (institution): Taiho; Research grant / Funding (institution): Akeso; Research grant / Funding (institution): MedImmune; Research grant / Funding (institution): Aptevo; Leadership role, Chair - GU Tumour Group: Cancer Trials Australia; Leadership role, Chair - Germ Cell Tumour Subcommittee, Member - Scientific Advisory Committee: ANZUP; Leadership role, Member - Scientific Advisory Committee: Biogrid; Leadership role, Member - Scientific Advisory Committee: Parkville Cancer Clinical Trials Unit; Leadership role, Co-Chair - Molecular Tumour Board: Victorian Comprehensive Cancer Centre.

Prognostic immunoprofiling of muscle invasive bladder cancer (MIBC) patients in a multicentre setting

Clinical Trials Unit

Funding Cancer Research UK, MRC Clinical Trials Unit at UCL, Canadian Cancer Trials Group.

Timing of radiotherapy (RT) after radical prostatectomy (RP): First results from the RADICALS RT randomised controlled trial (RCT) [NCT00541047]

More Clinical Trials Unit sentences More Sentences

Trials Unit sentence examples within Phase Trials Unit

Phase Trials Unit

Early Phase Trials Unit.

Opções Contemporâneas de Rastreio da Cardiotoxicidade Relacionada a Tratamentos Oncológicos

Phase Trials Unit

We analyzed the overall outcomes and survival of 91 patients enrolled onto one of 14 Phase I and I/II trials for hematological malignancies at a dedicated early phase trials unit within a tertiary hematology unit.

Clinical outcomes and survival of patients with myeloma and lymphoma enrolled into phase I clinical trials

More Phase Trials Unit sentences More Sentences

Trials Unit sentence examples within Cancer Trials Unit

Cancer Trials Unit

Hillmen Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom; CR-UK Liverpool Cancer Trials Unit, University of Liverpool, Liverpool, United Kingdom; Liverpool Clinical Laboratories, Haemato-Oncology Diagnostic Service, Liverpool, United Kingdom; Liverpool Clinical Laboratories, Department of Blood Sciences, Liverpool, United Kingdom; Department of Haematology, Kent & Canterbury Hospital, Canterbury, United Kingdom; Russells Hall Hospital, Haematology Unit, Dudley, United Kingdom; Department of Oncology, University of Oxford, Oxford, United Kingdom; Department of Haematology, Sandwell Hospital, Birmingham, United Kingdom; Department of Haematology, Maidstone Hospital, Maidstone, United Kingdom; Department of Haematology, University Hospital Southampton, Southampton, United Kingdom; Department of Haematology & Blood Transfusion, Southend Hospital, Southend, United Kingdom; Department of Haematology, Heartlands Hospital, Birmingham, United Kingdom; Department of Haematology, Medway Maritime Hospital, Gillingham, United Kingdom; Department of Clinical Haematology, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom; Department of Clinical Haematology, Royal United Hospital, Bath, United Kingdom; Department of Haematology, Colchester General Hospital, Colchester, United Kingdom; Oncology Unit, Torbay Hospital, Torquay, United Kingdom; Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom.

BRIEF CO‐ADMINISTRATION OF IDELALISIB MAY IMPROVE THE LONG‐TERM EFFICACY OF FRONTLINE CHEMOIMMUNOTHERAPY IN CHRONIC LYMPHOCYTIC LEUKAEMIA: 3‐YEAR FOLLOW‐UP FROM THE RIALTO TRIAL

Cancer Trials Unit

Legal entity responsible for the study Comprehensive Cancer Trials Unit, Department of Clinical Oncology, The Chinese University of Hong Kong.

Development and validation of a risk model integrating plasma Epstein-Barr virus DNA (EBV DNA) level and TNM stage for stratification of nasopharyngeal cancer (NPC) to adjuvant therapy

More Cancer Trials Unit sentences More Sentences

Learn more from Trials Unit

More Trials Unit sentence examples
10.1093/annonc/mdz239.067

Tran: Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self), Research grant / Funding (institution), Travel / Accommodation / Expenses: Amgen; Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self), Travel / Accommodation / Expenses: Astellas; Honoraria (self), Advisory / Consultancy, Research grant / Funding (self), Travel / Accommodation / Expenses: Bayer; Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self): BMS; Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self), Research grant / Funding (institution), Non-remunerated activity/ies: Janssen-Cilag; Honoraria (self), Advisory / Consultancy, Research grant / Funding (institution): MSD; Honoraria (self), Advisory / Consultancy, Research grant / Funding (institution): Novartis; Honoraria (self), Advisory / Consultancy, Travel / Accommodation / Expenses: Sanofi; Honoraria (self), Advisory / Consultancy: Tolmar; Honoraria (self), Advisory / Consultancy, Research grant / Funding (self): Ipsen; Research grant / Funding (self), Research grant / Funding (institution): AstraZeneca; Research grant / Funding (self): Pfizer; Research grant / Funding (self), Research grant / Funding (institution): Servier; Research grant / Funding (institution): Aslan; Research grant / Funding (institution): GSK; Research grant / Funding (institution): Taiho; Research grant / Funding (institution): Akeso; Research grant / Funding (institution): MedImmune; Research grant / Funding (institution): Aptevo; Leadership role, Chair - GU Tumour Group: Cancer Trials Australia; Leadership role, Chair - Germ Cell Tumour Subcommittee, Member - Scientific Advisory Committee: ANZUP; Leadership role, Member - Scientific Advisory Committee: Biogrid; Leadership role, Member - Scientific Advisory Committee: Parkville Cancer Clinical Trials Unit; Leadership role, Co-Chair - Molecular Tumour Board: Victorian Comprehensive Cancer Centre.

Prognostic immunoprofiling of muscle invasive bladder cancer (MIBC) patients in a multicentre setting

More Trials Unit sentence examples
10.1093/annonc/mdz394.042

Funding Cancer Research UK, MRC Clinical Trials Unit at UCL, Canadian Cancer Trials Group.

Timing of radiotherapy (RT) after radical prostatectomy (RP): First results from the RADICALS RT randomised controlled trial (RCT) [NCT00541047]

More Trials Unit sentence examples
10.32635/2176-9745.rbc.2019v65n3.388

Early Phase Trials Unit.

Opções Contemporâneas de Rastreio da Cardiotoxicidade Relacionada a Tratamentos Oncológicos

More Trials Unit sentence examples
10.1016/S2213-2600(19)30367-4

Patients were randomly assigned (1:1) to biomarker-guided recommendation on antibiotics (intervention group) or routine use of antibiotics (control group) using a web-based randomisation service hosted by Newcastle Clinical Trials Unit.

Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation

More Trials Unit sentence examples
10.1002/14651858.CD012918.pub2

gov, the Clinical Trials Unit of the International Union Against Tuberculosis and Lung Disease, the UK Medical Research Council Clinical Trials Unit, and the Clinical Trials Registry India for ongoing trials.

Shortened treatment regimens versus the standard regimen for drug‐sensitive pulmonary tuberculosis

More Trials Unit sentence examples
10.3310/eme06080

Very low-dose dexamethasone to facilitate extubation of preterm babies at risk of bronchopulmonary dysplasia: the MINIDEX feasibility RCT Helen Yates,1* Virginia Chiocchia,2 Louise Linsell,2 Nicolas Orsi,3 Edmund Juszczak,2 Kathryn Johnson,4 Philip Chetcuti,4 Claire Illingworth,5 Pollyanna Hardy,6 Vaneesha Monk,7 Simon Newell8† and Mark Turner9 1Department of Neonatal Medicine, Women and Children’s Hospital, Hull Royal Infirmary, Hull, UK 2NPEU Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK 3Women’s Health Research Group, Leeds Institute of Cancer and Pathology, St James’s University Hospital, Leeds, UK 4Leeds Neonatal Service, Leeds General Infirmary, Leeds, UK 5Patient and public involvement representative 6Birmingham Clinical Trials Unit, Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK 7Department of Paediatrics, University of Oxford, John Radcliffe Hospital, Oxford, UK 8Leeds Teaching Hospitals NHS Trust, Leeds, UK 9Neonatal Unit, Liverpool Women’s Hospital, Liverpool, UK *Corresponding author Helen.

Very low-dose dexamethasone to facilitate extubation of preterm babies at risk of bronchopulmonary dysplasia: the MINIDEX feasibility RCT

More Trials Unit sentence examples
10.1007/s11524-019-00391-z

We assessed an integrated, multi-pronged strategy for improving youth’s timely linkage to care carried out in eight adolescent medicine clinical trials units (AMTUs) in the USA.

Improving Timely Linkage to Care among Newly Diagnosed HIV-Infected Youth: Results of SMILE

More Trials Unit sentence examples
10.1136/ejhpharm-2019-eahpconf.398

Material and methods The software was installed in the pharmacy-based Clinical Trials Unit in July 2018.

4CPS-249 Implementation of an integrated software for clinical trials management and automated preparation of investigational drugs in a hospital pharmacy

More Trials Unit sentence examples
10.1111/add.14552

SETTING Clinical Trials Units in St Olav's Hospital, Trondheim and Rikshospitalet, Oslo, Norway.

Pharmacokinetics of a novel, approved, 1.4‐mg intranasal naloxone formulation for reversal of opioid overdose—a randomized controlled trial

More Trials Unit sentence examples
10.1177/1740774519881619

In brief, we conducted a survey of 38 United Kingdom–registered Clinical Trials Units, reviewed a cohort of 264 published trials, observed 8 third oversight committee meetings and interviewed 52 trialists.

A third trial oversight committee: Functions, benefits and issues

More Trials Unit sentence examples
10.3310/hta23430

The trial was supported by the Cancer Research UK Prevention Trials Unit (grant A16893).

E-cigarettes compared with nicotine replacement therapy within the UK Stop Smoking Services: the TEC RCT.

More Trials Unit sentence examples
10.20411/PAI.V4I1.305

He led a highly successful AIDS Clinical Trials Unit at the University of North Carolina and was a respected leader in this national consortium who gained international recognition and respect for his work.

Charlie van der Horst (1952-2019)

More Trials Unit sentence examples
10.1701/3182.31609

Adopt Clinical Trials Units officially and contractually recognized would be essential to bring back our nation on the top of the world health systems ranking, but yet the Italian research-dedicated infrastructures continue to be a ghost reality, deeply characterized by a continuous professional turnover and by the lack of long-term prospects.

Ricerca clinica: abbastanza giocatori per vincere la partita?

More Trials Unit sentence examples
10.1080/14659891.2019.1572801

Abbreviations: SUDs: substance use disorders; STIs: sexually transmitted infections; CODs: co-occurring disorders; UEC-INPRFM: clinical trials unit in addiction and mental health-national institute of psychiatry ramón de la fuente muñiz.

Rapid testing and counseling for HIV/STIs in Mexican community-based residential care facilities for substance use disorders: A prospective study protocol

More Trials Unit sentence examples
10.1097/01.JU.0000555458.91980.fe

TRoMbone aimed to recruit 50 men over a 12-month period and was co-ordinated by the Surgical Intervention Trials Unit at the University of Oxford.

PD15-09 TROMBONE: TESTING RADICAL PROSTATECTOMY IN MEN WITH OLIGOMETASTATIC PROSTATE CANCER THAT HAS SPREAD TO THE BONE- A RANDOMIZED CONTROLLED FEASIBILITY TRIAL

More Trials Unit sentence examples
10.1038/s41571-019-0236-y

12Cancer Research UK Clinical Trials Unit, Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham, UK.

Reply to ‘Assembling the brain trust: the multidisciplinary imperative in neuro-oncology’

More Trials Unit sentence examples
10.3310/hta23570

Central trials unit computerised randomisation in four consecutive cohorts within each of the seven centres.

Group cognitive-behavioural programme to reduce the impact of rheumatoid arthritis fatigue: the RAFT RCT with economic and qualitative evaluations.

More Trials Unit sentence examples
10.1093/annonc/mdz248.007

Legal entity responsible for the study Medical Research Council-Clinical Trials Unit and University of Manchester.

Benefit of prostate radiotherapy for patients with lymph node only or < 4 bone metastasis and no visceral metastases: Exploratory analyses of metastatic site and number in the STAMPEDE “M1|RT comparison”

More Trials Unit sentence examples
10.20944/preprints201910.0318.v1

Early Phase Clinical Trials Unit, Department of Oncology, University of Oxford, United Kingdom.

Megavoltage Radiosensitization of Gold Nanoparticles on Glioblastoma Cancer Cell Line Using a Clinical Platform

More Trials Unit sentence examples
10.1136/BMJGH-2019-EDC.1

Outstanding Research Team Prize The prize was awarded to the team of the CHAPAS (Children with HIV in Africa – Pharmacokinetics and acceptability of simple antiretroviral regimens) studies, led by Professor Diana Gibb (MRC Clinical Trials Unit, United Kingdom).

THE NINTH FORUM OF THE EUROPEAN & DEVELOPING COUNTRIES CLINICAL TRIALS PARTNERSHIP

More Trials Unit sentence examples
10.1016/j.clon.2019.10.004

Four main themes around trial set-up were identified from semi-structured interviews: the importance of communication and building relationships, the previous experience of the chief investigator and clinical trials units, a lack of resources and having the time and personnel required to produce trial documentation and to process trial approval requests.

Radiotherapy Trial Set-up in the UK: Identifying Inefficiencies and Potential Solutions.

More Trials Unit sentence examples
10.5580/b14

She is an attending physician in the Cutaneous Lymphoma Clinic, Extracorporeal Photopheresis Program, and the Clinical Trials Unit where she participates in multicenter clinical trials for refractory CTCL.

Management of Co-existing Mycosis Fungoides and Lymphomatoid Papulosis

More Trials Unit sentence examples
10.1186/s13063-019-3322-7

FOCUS4 (colorectal cancer) and STAMPEDE (prostate cancer), run from the Medical Research Council Clinical Trials Unit (CTU) at UCL, are two leading UK examples of clinical trials implementing adaptive platform protocol designs.

Changing platforms without stopping the train: experiences of data management and data management systems when adapting platform protocols by adding and closing comparisons

More Trials Unit sentence examples
10.1186/s13063-019-3377-5

The trials unit at University College London has been at the forefront of this work, with ground-breaking trials such as STAMPEDE and FOCUS4.

Mind the gap? The platform trial as a working environment

More Trials Unit sentence examples
10.1111/1471-0528.15496

JOHN ALLOTEY, WOMEN’S HEALTH RESEARCH UNIT, BARTS AND THE LONDON SCHOOL OF MEDICINE AND DENTISTRY, QUEEN MARY UNIVERSITY OF LONDON, LONDON, UK, AND NADINE MARLIN, PRAGMATIC CLINICAL TRIALS UNIT, BARTS AND THE LONDON SCHOOL OF MEDICINE AND DENTISTRY, QUEEN MARY UNIVERSITY LONDON, LONDON, UK.

Well‐conducted randomisation will improve balance and reliability of treatment estimates

More Trials Unit sentence examples
10.3310/EME06040

Eicosapentaenoic acid and/or aspirin for preventing colorectal adenomas during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme: the seAFOod RCT Mark A Hull,1* Kirsty Sprange,2 Trish Hepburn,2 Wei Tan,2 Aisha Shafayat,2 Colin J Rees,3 Gayle Clifford,4 Richard F Logan,5 Paul M Loadman,6 Elizabeth A Williams,7 Diane Whitham2 and Alan A Montgomery2 on behalf of the seAFOod Collaborative Group 1Leeds Institute of Medical Research, University of Leeds, St James’s University Hospital, Leeds, UK 2Nottingham Clinical Trials Unit, Queen’s Medical Centre, School of Medicine, University of Nottingham, Nottingham, UK 3Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK 4South Tyneside District Hospital, South Tyneside NHS Foundation Trust, South Shields, UK 5Nottingham Digestive Diseases Centre, Queen’s Medical Centre, University of Nottingham, Nottingham, UK 6School of Pharmacy and Medical Sciences, Institute of Cancer Therapeutics, University of Bradford, Bradford, UK 7Department of Oncology & Metabolism, Human Nutrition Unit, The Medical School, University of Sheffield, Sheffield, UK *Corresponding author M.

Eicosapentaenoic acid and/or aspirin for preventing colorectal adenomas during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme: the seAFOod RCT

More Trials Unit sentence examples
10.1136/BMJ.L2403

Dormandy, who became a consultant vascular surgeon at St George’s Hospital in 1973, would later set up a clinical trials unit there for new treatments and comparisons of drug therapy.

John Adam Dormandy: championed new approaches to tackling peripheral arterial disease

More Trials Unit sentence examples
10.23889/IJPDS.V4I1.1104

SE1 0BW 7Clinical Trials Unit, Medical School, Warwick University Faculty of Health, Social Care and Education, Kingston University and St George’s, University of London, London SW17 0RE 827 Devonshire Way, Croydon, CR0 8BU.

Using deterministic record linkage to link ambulance and emergency department data: is it possible without patient identifiers?

More Trials Unit sentence examples
10.1002/jbmr.3899

Andrew D Duckworth, Margaret M McQueen, Christopher E Tuck, Jonathan H Tobias, Jeremy Mark Wilkinson, Leela C Biant, Elizabeth Claire Pulford, Stephen Aldridge, Claire Edwards, Chris P Roberts, Manoj Ramachandran, Andrew Richard McAndrew, Kenneth C K Cheng, Phillip Johnston, Nasir H Shah, Philip Mathew, John Harvie, Birgit C Hanusch, Ronnie Harkess, Aryelly Rodriguez, Gordon D Murray, and Stuart H Ralston Edinburgh Clinical Trials Unit, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK Edinburgh Orthopaedic Trauma, Royal Infirmary of Edinburgh, Edinburgh, UK Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK Trauma and Orthopaedic Surgery, University of Manchester, Manchester, UK Oxford University Hospitals NHS Foundation Trust, Headington, UK The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK Norfolk and Norwich University Hospital Foundation Trust, Norwich, UK Ipswich Hospital NHS Trust, Ipswich, UK Royal London Hospital, Barts Health NHS Trust, London, UK Royal Berkshire Hospital Foundation Trust, Reading, UK NHS Ayrshire and Arran, Ayr, UK Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Warrington and Halton Hospitals NHS Foundation Trust, Warrington, UK Queen’s Hospital, Romford, UK Raigmore Hospital, Inverness, UK South Tees, Hospitals NHS Foundation Trust, Middlesbrough, UK Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

Response to: Effects of Alendronic Acid on Fracture Healing

More Trials Unit sentence examples
10.1177/1740774519834257

Methods The study was carried out at a single phase I clinical trials unit.

Comprehension and recall from the informed consent process by phase I healthy volunteers before dose administration

More Trials Unit sentence examples
10.2337/DB19-39-LB

Methods: Masked 2 arm, parallel assignment, equivalence RCT (largest to date in screening) with independent trials unit monitoring in people with diabetes aged ≥12 years attending screening in a single English program.

39-LB: Individualised Screening for Diabetic Retinopathy: The ISDR Study—A Randomised Controlled Trial of Safety, Efficacy, and Cost-Effectiveness

More Trials Unit sentence examples
10.1002/HON.32_2630

Hillmen Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom; CR-UK Liverpool Cancer Trials Unit, University of Liverpool, Liverpool, United Kingdom; Liverpool Clinical Laboratories, Haemato-Oncology Diagnostic Service, Liverpool, United Kingdom; Liverpool Clinical Laboratories, Department of Blood Sciences, Liverpool, United Kingdom; Department of Haematology, Kent & Canterbury Hospital, Canterbury, United Kingdom; Russells Hall Hospital, Haematology Unit, Dudley, United Kingdom; Department of Oncology, University of Oxford, Oxford, United Kingdom; Department of Haematology, Sandwell Hospital, Birmingham, United Kingdom; Department of Haematology, Maidstone Hospital, Maidstone, United Kingdom; Department of Haematology, University Hospital Southampton, Southampton, United Kingdom; Department of Haematology & Blood Transfusion, Southend Hospital, Southend, United Kingdom; Department of Haematology, Heartlands Hospital, Birmingham, United Kingdom; Department of Haematology, Medway Maritime Hospital, Gillingham, United Kingdom; Department of Clinical Haematology, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom; Department of Clinical Haematology, Royal United Hospital, Bath, United Kingdom; Department of Haematology, Colchester General Hospital, Colchester, United Kingdom; Oncology Unit, Torbay Hospital, Torquay, United Kingdom; Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom.

BRIEF CO‐ADMINISTRATION OF IDELALISIB MAY IMPROVE THE LONG‐TERM EFFICACY OF FRONTLINE CHEMOIMMUNOTHERAPY IN CHRONIC LYMPHOCYTIC LEUKAEMIA: 3‐YEAR FOLLOW‐UP FROM THE RIALTO TRIAL

More Trials Unit sentence examples
10.1513/AnnalsATS.201809-620CME

Feller-Kopman Division of Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City, Utah; Division of Thoracic Surgery, Northwestern Memorial Hospital, Chicago, Illinois; Doctor Evidence LLC, Santa Monica, California; Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California; Howard Hughes Medical Institute, University of California San Francisco, San Francisco, California; Children’s Hospital Los Angeles, Los Angeles, California; Department of Medicine and Lung Institute of Western Australia, University of Western Australia, Perth, Western Australia, Australia; Academic Respiratory Unit, University of Bristol, Bristol, United Kingdom; Oxford Respiratory Trials Unity, University of Oxford, Oxford, United Kingdom; Department of Pulmonary, Critical Care, and Sleep Medicine, NYU Langone Medicine Center, New York, New York; Department of Pulmonary and Critical Care Medicine, Duke University School ofMedicine, Durham,North Carolina; Division of Pulmonary andCritical CareMedicine, University of Southern California, Los Angeles, California; and Pulmonary and Critical Care Division, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Summary for Clinicians: Clinical Practice Guideline for Management of Malignant Pleural Effusions

More Trials Unit sentence examples
10.1111/bjh.15457

We analyzed the overall outcomes and survival of 91 patients enrolled onto one of 14 Phase I and I/II trials for hematological malignancies at a dedicated early phase trials unit within a tertiary hematology unit.

Clinical outcomes and survival of patients with myeloma and lymphoma enrolled into phase I clinical trials

More Trials Unit sentence examples
10.1007/s10974-019-09534-w

---------------------------------------------------------------------------------------------------------------Implications of Demographic Changes on Familial Care Resources -With illustrative application to Hebei province of China Zhenglian Wang, Xianling Zhang and Yi Zeng ---------------------------------------------------------------------------------------------------------------Applications of multi-state models in hematology: bridging the gap Liesbeth de Wreede (LUMC Department of Medical Statistics and Bioinformatics and DKMS, Clinical Trials Unit) In methodological papers on multi-state models in biostatistical journals, their use is often motivated by applications in the field of hematopoietic stem cell (or bone marrow) transplantation (SCT).

Talks

More Trials Unit sentence examples
10.1016/S0140-6736(19)31948-8

METHODS We did a 52-week, open-label, parallel-group, multicentre, superiority, randomised controlled trial at 15 primary care or hospital-based clinical trials units and primary care practices in New Zealand.

Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL): a 52-week, open-label, multicentre, superiority, randomised controlled trial

More Trials Unit sentence examples
10.1186/s13063-019-3343-2

We reviewed these statistics at regular trials unit team meetings.

Early warnings and repayment plans: novel trial management methods for monitoring and managing data return rates in a multi-centre phase III randomised controlled trial with paper Case Report Forms

More Trials Unit sentence examples
10.1136/BMJEBM-2019-POD.18

Systematic review and meta–analysis of randomised trials (RCTs) of surveillance of increasing intensity for recurrence of colorectal cancer was conducted in collaboration with Erasmus University Rotterdam, Cambridge MRC Biostatistics Unit, the Surgical and Interventional Trials Unit (UCL) A ‘Big data’ analysis was conducted to re–examine published NHS data The PulMiCC trial (Pulmonary Metastasectomy in Colorectal Cancer) is an RCT recruiting participants referred for consideration of lung metastasectomy into a registered cohort.

4 False hope, capitalising on fear, and cultural obstacles to heeding randomised trial evidence concerning secondary surveillance and metastasectomy in colorectal cancer

More Trials Unit sentence examples
10.3310/hta23640

This research was supported by the Medical Research Council (transferred to NIHR Evaluation, Trials and Studies Coordinating Centre - Efficacy and Mechanism Evaluation; grant reference G0601705), the Swedish Cancer Society and Cancer Research UK Core Clinical Trials Unit Funding (funding reference C6716/A9894).

3-month versus 6-month adjuvant chemotherapy for patients with high-risk stage II and III colorectal cancer: 3-year follow-up of the SCOT non-inferiority RCT.

More Trials Unit sentence examples
10.1093/jpepsy/jsy076

Methods Behaviorally infected youth living with HIV ages 13-24 (N = 822) from 14 sites within the Adolescent Medicine Trials Unit (AMTU) were included in the study.

A Multi-Site Study of Social Cognitive Factors Related to Adherence Among Youth Living With HIV in the New Era of Antiretroviral Medication

More Trials Unit sentence examples
10.3310/phr07040

Visually Impaired OLder people’s Exercise programme for falls prevenTion (VIOLET): a feasibility study Nicola Adams,1* Dawn Skelton,2 Cathy Bailey,1 Denise Howel,3 Dorothy Coe,1 Rosy Lampitt,4 Jennifer Wilkinson,4 Tony Fouweather,3 Lex de Jong,2 Sheena Gawler,1 Vincent Deary,1 Joanne Gray,1 Heather Waterman5 and Steve Parry6 1Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK 2Institute of Applied Health Research, School of Health and Life Sciences, Centre for Living, Glasgow Caledonian University, Glasgow, UK 3Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK 4Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK 5Healthcare Sciences, Cardiff University, Cardiff, UK 6Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK *Corresponding author nicola.

Visually Impaired OLder people’s Exercise programme for falls prevenTion (VIOLET): a feasibility study

More Trials Unit sentence examples
10.1002/hon.40_2629

The trial is coordinated by the CRUK Southampton Clinical Trials Unit.

TELLOMAK: T‐CELL LYMPHOMA ANTI‐KIR3DL2 THERAPY: AN OPEN LABEL, MULTI‐COHORT, MULTI‐CENTER, INTERNATIONAL PHASE II STUDY EVALUATING THE EFFICACY AND SAFETY OF IPH4102 ALONE OR IN COMBINATION WITH CHEMOTHERAPY IN PATIENTS WITH ADVANCED T‐CELL LYMPHOMA

More Trials Unit sentence examples
10.1111/1471-0528.15498

NADINE MARLIN, PRAGMATIC CLINICAL TRIALS UNIT, BARTS AND THE LONDON SCHOOL OF MEDICINE AND DENTISTRY, QUEEN MARY UNIVERSITY LONDON, LONDON, UK, AND JOHN ALLOTEY, WOMEN’S HEALTH RESEARCH UNIT, BARTS AND THE LONDON SCHOOL OF MEDICINE AND DENTISTRY, QUEEN MARY UNIVERSITY OF LONDON, LONDON, UK.

Baseline 101 – who is who?

More Trials Unit sentence examples
10.3310/phr07160

This study was designed and delivered in collaboration with the Bristol Randomised Trials Collaboration (BRTC), a UK CRC-registered clinical trials unit in receipt of NIHR clinical trials unit support funding.

A peer-led physical activity intervention in schools for adolescent girls: a feasibility RCT

More Trials Unit sentence examples
10.1002/14651858.CD012918

gov, the Clinical Trials Unit of the International Union Against Tuberculosis and Lung Disease, the UK Medical Research Council Clinical Trials Unit, and the Clinical Trials Registry India for ongoing trials.

Shortened treatment regimens versus the standard regimen for drug‐sensitive pulmonary tuberculosis

More Trials Unit sentence examples
10.1016/S2468-1253(19)30289-4

FUNDING Cancer Research UK, The National Institute for Health Research Health Technology Assessment Programme, The MRC Clinical Trials Unit at UCL.

Aspirin as an adjuvant treatment for cancer: feasibility results from the Add-Aspirin randomised trial.

More Trials Unit sentence examples
10.1080/00031305.2019.1680048

Cattolica del Sacro Cuore Italy * Andrew Copas, MRC Clinical Trials Unit at UCL United Kingdom of Great Britain and Northern Ireland Kishore Kuma Das, Gauhati Univ.

Editorial Collaborators

More Trials Unit sentence examples
10.1093/annonc/mdz428.001

Legal entity responsible for the study Comprehensive Cancer Trials Unit, Department of Clinical Oncology, The Chinese University of Hong Kong.

Development and validation of a risk model integrating plasma Epstein-Barr virus DNA (EBV DNA) level and TNM stage for stratification of nasopharyngeal cancer (NPC) to adjuvant therapy

More Trials Unit sentence examples
10.14283/jpad.2019.15

The Dominantly Inherited Alzheimer Network (DIAN) Trials Unit (TU) secondary prevention trial, incorporating two treatment arms with the monoclonal antibodies solanezumab and gantenerumab that target amyloid-beta, in individuals from families with autosomal dominant AD (7) completed enrollment and randomization in 2015; analyses to determine whether cognitive benefit was achieved should begin before 2021.

Is Now the Time for Combination Therapies for Alzheimer Disease?

More Trials Unit sentence examples
10.1177/1740774519862528

As a consequence of the positive results, AstraZeneca was engaged with the Medical Research Council trials unit to discuss regulatory submission using ICON6 as the single pivotal trial.

Impact of retrospective data verification to prepare the ICON6 trial for use in a marketing authorization application

More Trials Unit sentence examples
10.1701/3182.31609

Adopt Clinical Trials Units officially and contractually recognized would be essential to bring back our nation on the top of the world health systems ranking, but yet the Italian research-dedicated infrastructures continue to be a ghost reality, deeply characterized by a continuous professional turnover and by the lack of long-term prospects.

[Clinical research: enough players to get out there?]

More Trials Unit sentence examples
10.15131/SHEF.DATA.7578242.V1

This study is being conducted by the Clinical Trials Unit at the University of Sheffield.

The PITSTOP Study: PIlonidal sinus Treatment: STudying the OPtions - Protocol

More Trials Unit sentence examples
10.1186/s13063-019-3619-6

This study compared current risk assessment and monitoring approaches in UK Clinical Trials Units (CTUs) with the published guidance and makes recommendations for risk-based monitoring in pragmatic trials.

An evaluation of risk-based monitoring in pragmatic trials in UK Clinical Trials Units

More Trials Unit sentence examples
10.1186/s13063-019-3451-z

This article highlights some of the key barriers to achieving this and makes suggestions on how they can be addressed within clinical trials units registered with the UK Clinical Research Collaboration.

Trial management: we need a cadre of high-class triallists to deliver the answers that patients need

More Trials Unit sentence examples
10.1017/s0266462319003180

The aim of this UK Clinical Trials Unit (CTU) survey was to identify which digital recruitment and retention tools are being used to support RCTs, their benefits and success characteristics.

VP54 Digital Tools For More Efficient Conduct Of RCTs: Trials Unit Survey

Learn more from Trials Unit

Keywords related to Trials

Trials Unit
Encyclopedia

What is/are Trials Unit?

Trials Unit - Tran: Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self), Research grant / Funding (institution), Travel / Accommodation / Expenses: Amgen; Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self), Travel / Accommodation / Expenses: Astellas; Honoraria (self), Advisory / Consultancy, Research grant / Funding (self), Travel / Accommodation / Expenses: Bayer; Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self): BMS; Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self), Research grant / Funding (institution), Non-remunerated activity/ies: Janssen-Cilag; Honoraria (self), Advisory / Consultancy, Research grant / Funding (institution): MSD; Honoraria (self), Advisory / Consultancy, Research grant / Funding (institution): Novartis; Honoraria (self), Advisory / Consultancy, Travel / Accommodation / Expenses: Sanofi; Honoraria (self), Advisory / Consultancy: Tolmar; Honoraria (self), Advisory / Consultancy, Research grant / Funding (self): Ipsen; Research grant / Funding (self), Research grant / Funding (institution): AstraZeneca; Research grant / Funding (self): Pfizer; Research grant / Funding (self), Research grant / Funding (institution): Servier; Research grant / Funding (institution): Aslan; Research grant / Funding (institution): GSK; Research grant / Funding (institution): Taiho; Research grant / Funding (institution): Akeso; Research grant / Funding (institution): MedImmune; Research grant / Funding (institution): Aptevo; Leadership role, Chair - GU Tumour Group: Cancer Trials Australia; Leadership role, Chair - Germ Cell Tumour Subcommittee, Member - Scientific Advisory Committee: ANZUP; Leadership role, Member - Scientific Advisory Committee: Biogrid; Leadership role, Member - Scientific Advisory Committee: Parkville Cancer Clinical Trials Unit; Leadership role, Co-Chair - Molecular Tumour Board: Victorian Comprehensive Cancer Centre. [1] Funding Cancer Research UK, MRC Clinical Trials Unit at UCL, Canadian Cancer Trials Group. [2] Early Phase Trials Unit. [3] Patients were randomly assigned (1:1) to biomarker-guided recommendation on antibiotics (intervention group) or routine use of antibiotics (control group) using a web-based randomisation service hosted by Newcastle Clinical Trials Unit. [4] gov, the Clinical Trials Unit of the International Union Against Tuberculosis and Lung Disease, the UK Medical Research Council Clinical Trials Unit, and the Clinical Trials Registry India for ongoing trials. [5] Very low-dose dexamethasone to facilitate extubation of preterm babies at risk of bronchopulmonary dysplasia: the MINIDEX feasibility RCT Helen Yates,1* Virginia Chiocchia,2 Louise Linsell,2 Nicolas Orsi,3 Edmund Juszczak,2 Kathryn Johnson,4 Philip Chetcuti,4 Claire Illingworth,5 Pollyanna Hardy,6 Vaneesha Monk,7 Simon Newell8† and Mark Turner9 1Department of Neonatal Medicine, Women and Children’s Hospital, Hull Royal Infirmary, Hull, UK 2NPEU Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK 3Women’s Health Research Group, Leeds Institute of Cancer and Pathology, St James’s University Hospital, Leeds, UK 4Leeds Neonatal Service, Leeds General Infirmary, Leeds, UK 5Patient and public involvement representative 6Birmingham Clinical Trials Unit, Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK 7Department of Paediatrics, University of Oxford, John Radcliffe Hospital, Oxford, UK 8Leeds Teaching Hospitals NHS Trust, Leeds, UK 9Neonatal Unit, Liverpool Women’s Hospital, Liverpool, UK *Corresponding author Helen. [6] We assessed an integrated, multi-pronged strategy for improving youth’s timely linkage to care carried out in eight adolescent medicine clinical trials units (AMTUs) in the USA. [7] Material and methods The software was installed in the pharmacy-based Clinical Trials Unit in July 2018. [8] SETTING Clinical Trials Units in St Olav's Hospital, Trondheim and Rikshospitalet, Oslo, Norway. [9] In brief, we conducted a survey of 38 United Kingdom–registered Clinical Trials Units, reviewed a cohort of 264 published trials, observed 8 third oversight committee meetings and interviewed 52 trialists. [10] The trial was supported by the Cancer Research UK Prevention Trials Unit (grant A16893). [11] He led a highly successful AIDS Clinical Trials Unit at the University of North Carolina and was a respected leader in this national consortium who gained international recognition and respect for his work. [12] Adopt Clinical Trials Units officially and contractually recognized would be essential to bring back our nation on the top of the world health systems ranking, but yet the Italian research-dedicated infrastructures continue to be a ghost reality, deeply characterized by a continuous professional turnover and by the lack of long-term prospects. [13] Abbreviations: SUDs: substance use disorders; STIs: sexually transmitted infections; CODs: co-occurring disorders; UEC-INPRFM: clinical trials unit in addiction and mental health-national institute of psychiatry ramón de la fuente muñiz. [14] TRoMbone aimed to recruit 50 men over a 12-month period and was co-ordinated by the Surgical Intervention Trials Unit at the University of Oxford. [15] 12Cancer Research UK Clinical Trials Unit, Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham, UK. [16] Central trials unit computerised randomisation in four consecutive cohorts within each of the seven centres. [17] Legal entity responsible for the study Medical Research Council-Clinical Trials Unit and University of Manchester. [18] Early Phase Clinical Trials Unit, Department of Oncology, University of Oxford, United Kingdom. [19] Outstanding Research Team Prize The prize was awarded to the team of the CHAPAS (Children with HIV in Africa – Pharmacokinetics and acceptability of simple antiretroviral regimens) studies, led by Professor Diana Gibb (MRC Clinical Trials Unit, United Kingdom). [20] Four main themes around trial set-up were identified from semi-structured interviews: the importance of communication and building relationships, the previous experience of the chief investigator and clinical trials units, a lack of resources and having the time and personnel required to produce trial documentation and to process trial approval requests. [21] She is an attending physician in the Cutaneous Lymphoma Clinic, Extracorporeal Photopheresis Program, and the Clinical Trials Unit where she participates in multicenter clinical trials for refractory CTCL. [22] FOCUS4 (colorectal cancer) and STAMPEDE (prostate cancer), run from the Medical Research Council Clinical Trials Unit (CTU) at UCL, are two leading UK examples of clinical trials implementing adaptive platform protocol designs. [23] The trials unit at University College London has been at the forefront of this work, with ground-breaking trials such as STAMPEDE and FOCUS4. [24] JOHN ALLOTEY, WOMEN’S HEALTH RESEARCH UNIT, BARTS AND THE LONDON SCHOOL OF MEDICINE AND DENTISTRY, QUEEN MARY UNIVERSITY OF LONDON, LONDON, UK, AND NADINE MARLIN, PRAGMATIC CLINICAL TRIALS UNIT, BARTS AND THE LONDON SCHOOL OF MEDICINE AND DENTISTRY, QUEEN MARY UNIVERSITY LONDON, LONDON, UK. [25] Eicosapentaenoic acid and/or aspirin for preventing colorectal adenomas during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme: the seAFOod RCT Mark A Hull,1* Kirsty Sprange,2 Trish Hepburn,2 Wei Tan,2 Aisha Shafayat,2 Colin J Rees,3 Gayle Clifford,4 Richard F Logan,5 Paul M Loadman,6 Elizabeth A Williams,7 Diane Whitham2 and Alan A Montgomery2 on behalf of the seAFOod Collaborative Group 1Leeds Institute of Medical Research, University of Leeds, St James’s University Hospital, Leeds, UK 2Nottingham Clinical Trials Unit, Queen’s Medical Centre, School of Medicine, University of Nottingham, Nottingham, UK 3Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK 4South Tyneside District Hospital, South Tyneside NHS Foundation Trust, South Shields, UK 5Nottingham Digestive Diseases Centre, Queen’s Medical Centre, University of Nottingham, Nottingham, UK 6School of Pharmacy and Medical Sciences, Institute of Cancer Therapeutics, University of Bradford, Bradford, UK 7Department of Oncology & Metabolism, Human Nutrition Unit, The Medical School, University of Sheffield, Sheffield, UK *Corresponding author M. [26] Dormandy, who became a consultant vascular surgeon at St George’s Hospital in 1973, would later set up a clinical trials unit there for new treatments and comparisons of drug therapy. [27] SE1 0BW 7Clinical Trials Unit, Medical School, Warwick University Faculty of Health, Social Care and Education, Kingston University and St George’s, University of London, London SW17 0RE 827 Devonshire Way, Croydon, CR0 8BU. [28] Andrew D Duckworth, Margaret M McQueen, Christopher E Tuck, Jonathan H Tobias, Jeremy Mark Wilkinson, Leela C Biant, Elizabeth Claire Pulford, Stephen Aldridge, Claire Edwards, Chris P Roberts, Manoj Ramachandran, Andrew Richard McAndrew, Kenneth C K Cheng, Phillip Johnston, Nasir H Shah, Philip Mathew, John Harvie, Birgit C Hanusch, Ronnie Harkess, Aryelly Rodriguez, Gordon D Murray, and Stuart H Ralston Edinburgh Clinical Trials Unit, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK Edinburgh Orthopaedic Trauma, Royal Infirmary of Edinburgh, Edinburgh, UK Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK Trauma and Orthopaedic Surgery, University of Manchester, Manchester, UK Oxford University Hospitals NHS Foundation Trust, Headington, UK The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK Norfolk and Norwich University Hospital Foundation Trust, Norwich, UK Ipswich Hospital NHS Trust, Ipswich, UK Royal London Hospital, Barts Health NHS Trust, London, UK Royal Berkshire Hospital Foundation Trust, Reading, UK NHS Ayrshire and Arran, Ayr, UK Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Warrington and Halton Hospitals NHS Foundation Trust, Warrington, UK Queen’s Hospital, Romford, UK Raigmore Hospital, Inverness, UK South Tees, Hospitals NHS Foundation Trust, Middlesbrough, UK Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK. [29] Methods The study was carried out at a single phase I clinical trials unit. [30] Methods: Masked 2 arm, parallel assignment, equivalence RCT (largest to date in screening) with independent trials unit monitoring in people with diabetes aged ≥12 years attending screening in a single English program. [31] Hillmen Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom; CR-UK Liverpool Cancer Trials Unit, University of Liverpool, Liverpool, United Kingdom; Liverpool Clinical Laboratories, Haemato-Oncology Diagnostic Service, Liverpool, United Kingdom; Liverpool Clinical Laboratories, Department of Blood Sciences, Liverpool, United Kingdom; Department of Haematology, Kent & Canterbury Hospital, Canterbury, United Kingdom; Russells Hall Hospital, Haematology Unit, Dudley, United Kingdom; Department of Oncology, University of Oxford, Oxford, United Kingdom; Department of Haematology, Sandwell Hospital, Birmingham, United Kingdom; Department of Haematology, Maidstone Hospital, Maidstone, United Kingdom; Department of Haematology, University Hospital Southampton, Southampton, United Kingdom; Department of Haematology & Blood Transfusion, Southend Hospital, Southend, United Kingdom; Department of Haematology, Heartlands Hospital, Birmingham, United Kingdom; Department of Haematology, Medway Maritime Hospital, Gillingham, United Kingdom; Department of Clinical Haematology, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom; Department of Clinical Haematology, Royal United Hospital, Bath, United Kingdom; Department of Haematology, Colchester General Hospital, Colchester, United Kingdom; Oncology Unit, Torbay Hospital, Torquay, United Kingdom; Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom. [32] Feller-Kopman Division of Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City, Utah; Division of Thoracic Surgery, Northwestern Memorial Hospital, Chicago, Illinois; Doctor Evidence LLC, Santa Monica, California; Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California; Howard Hughes Medical Institute, University of California San Francisco, San Francisco, California; Children’s Hospital Los Angeles, Los Angeles, California; Department of Medicine and Lung Institute of Western Australia, University of Western Australia, Perth, Western Australia, Australia; Academic Respiratory Unit, University of Bristol, Bristol, United Kingdom; Oxford Respiratory Trials Unity, University of Oxford, Oxford, United Kingdom; Department of Pulmonary, Critical Care, and Sleep Medicine, NYU Langone Medicine Center, New York, New York; Department of Pulmonary and Critical Care Medicine, Duke University School ofMedicine, Durham,North Carolina; Division of Pulmonary andCritical CareMedicine, University of Southern California, Los Angeles, California; and Pulmonary and Critical Care Division, The Johns Hopkins University School of Medicine, Baltimore, Maryland. [33] We analyzed the overall outcomes and survival of 91 patients enrolled onto one of 14 Phase I and I/II trials for hematological malignancies at a dedicated early phase trials unit within a tertiary hematology unit. [34] ---------------------------------------------------------------------------------------------------------------Implications of Demographic Changes on Familial Care Resources -With illustrative application to Hebei province of China Zhenglian Wang, Xianling Zhang and Yi Zeng ---------------------------------------------------------------------------------------------------------------Applications of multi-state models in hematology: bridging the gap Liesbeth de Wreede (LUMC Department of Medical Statistics and Bioinformatics and DKMS, Clinical Trials Unit) In methodological papers on multi-state models in biostatistical journals, their use is often motivated by applications in the field of hematopoietic stem cell (or bone marrow) transplantation (SCT). [35] METHODS We did a 52-week, open-label, parallel-group, multicentre, superiority, randomised controlled trial at 15 primary care or hospital-based clinical trials units and primary care practices in New Zealand. [36] We reviewed these statistics at regular trials unit team meetings. [37] Systematic review and meta–analysis of randomised trials (RCTs) of surveillance of increasing intensity for recurrence of colorectal cancer was conducted in collaboration with Erasmus University Rotterdam, Cambridge MRC Biostatistics Unit, the Surgical and Interventional Trials Unit (UCL) A ‘Big data’ analysis was conducted to re–examine published NHS data The PulMiCC trial (Pulmonary Metastasectomy in Colorectal Cancer) is an RCT recruiting participants referred for consideration of lung metastasectomy into a registered cohort. [38] This research was supported by the Medical Research Council (transferred to NIHR Evaluation, Trials and Studies Coordinating Centre - Efficacy and Mechanism Evaluation; grant reference G0601705), the Swedish Cancer Society and Cancer Research UK Core Clinical Trials Unit Funding (funding reference C6716/A9894). [39] Methods Behaviorally infected youth living with HIV ages 13-24 (N = 822) from 14 sites within the Adolescent Medicine Trials Unit (AMTU) were included in the study. [40] Visually Impaired OLder people’s Exercise programme for falls prevenTion (VIOLET): a feasibility study Nicola Adams,1* Dawn Skelton,2 Cathy Bailey,1 Denise Howel,3 Dorothy Coe,1 Rosy Lampitt,4 Jennifer Wilkinson,4 Tony Fouweather,3 Lex de Jong,2 Sheena Gawler,1 Vincent Deary,1 Joanne Gray,1 Heather Waterman5 and Steve Parry6 1Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK 2Institute of Applied Health Research, School of Health and Life Sciences, Centre for Living, Glasgow Caledonian University, Glasgow, UK 3Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK 4Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK 5Healthcare Sciences, Cardiff University, Cardiff, UK 6Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK *Corresponding author nicola. [41] The trial is coordinated by the CRUK Southampton Clinical Trials Unit. [42] NADINE MARLIN, PRAGMATIC CLINICAL TRIALS UNIT, BARTS AND THE LONDON SCHOOL OF MEDICINE AND DENTISTRY, QUEEN MARY UNIVERSITY LONDON, LONDON, UK, AND JOHN ALLOTEY, WOMEN’S HEALTH RESEARCH UNIT, BARTS AND THE LONDON SCHOOL OF MEDICINE AND DENTISTRY, QUEEN MARY UNIVERSITY OF LONDON, LONDON, UK. [43] This study was designed and delivered in collaboration with the Bristol Randomised Trials Collaboration (BRTC), a UK CRC-registered clinical trials unit in receipt of NIHR clinical trials unit support funding. [44] gov, the Clinical Trials Unit of the International Union Against Tuberculosis and Lung Disease, the UK Medical Research Council Clinical Trials Unit, and the Clinical Trials Registry India for ongoing trials. [45] FUNDING Cancer Research UK, The National Institute for Health Research Health Technology Assessment Programme, The MRC Clinical Trials Unit at UCL. [46] Cattolica del Sacro Cuore Italy * Andrew Copas, MRC Clinical Trials Unit at UCL United Kingdom of Great Britain and Northern Ireland Kishore Kuma Das, Gauhati Univ. [47] Legal entity responsible for the study Comprehensive Cancer Trials Unit, Department of Clinical Oncology, The Chinese University of Hong Kong. [48] The Dominantly Inherited Alzheimer Network (DIAN) Trials Unit (TU) secondary prevention trial, incorporating two treatment arms with the monoclonal antibodies solanezumab and gantenerumab that target amyloid-beta, in individuals from families with autosomal dominant AD (7) completed enrollment and randomization in 2015; analyses to determine whether cognitive benefit was achieved should begin before 2021. [49] As a consequence of the positive results, AstraZeneca was engaged with the Medical Research Council trials unit to discuss regulatory submission using ICON6 as the single pivotal trial. [50]

Clinical Trials Unit

Tran: Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self), Research grant / Funding (institution), Travel / Accommodation / Expenses: Amgen; Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self), Travel / Accommodation / Expenses: Astellas; Honoraria (self), Advisory / Consultancy, Research grant / Funding (self), Travel / Accommodation / Expenses: Bayer; Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self): BMS; Honoraria (self), Advisory / Consultancy, Speaker Bureau / Expert testimony, Research grant / Funding (self), Research grant / Funding (institution), Non-remunerated activity/ies: Janssen-Cilag; Honoraria (self), Advisory / Consultancy, Research grant / Funding (institution): MSD; Honoraria (self), Advisory / Consultancy, Research grant / Funding (institution): Novartis; Honoraria (self), Advisory / Consultancy, Travel / Accommodation / Expenses: Sanofi; Honoraria (self), Advisory / Consultancy: Tolmar; Honoraria (self), Advisory / Consultancy, Research grant / Funding (self): Ipsen; Research grant / Funding (self), Research grant / Funding (institution): AstraZeneca; Research grant / Funding (self): Pfizer; Research grant / Funding (self), Research grant / Funding (institution): Servier; Research grant / Funding (institution): Aslan; Research grant / Funding (institution): GSK; Research grant / Funding (institution): Taiho; Research grant / Funding (institution): Akeso; Research grant / Funding (institution): MedImmune; Research grant / Funding (institution): Aptevo; Leadership role, Chair - GU Tumour Group: Cancer Trials Australia; Leadership role, Chair - Germ Cell Tumour Subcommittee, Member - Scientific Advisory Committee: ANZUP; Leadership role, Member - Scientific Advisory Committee: Biogrid; Leadership role, Member - Scientific Advisory Committee: Parkville Cancer Clinical Trials Unit; Leadership role, Co-Chair - Molecular Tumour Board: Victorian Comprehensive Cancer Centre. [1] Funding Cancer Research UK, MRC Clinical Trials Unit at UCL, Canadian Cancer Trials Group. [2] Patients were randomly assigned (1:1) to biomarker-guided recommendation on antibiotics (intervention group) or routine use of antibiotics (control group) using a web-based randomisation service hosted by Newcastle Clinical Trials Unit. [3] gov, the Clinical Trials Unit of the International Union Against Tuberculosis and Lung Disease, the UK Medical Research Council Clinical Trials Unit, and the Clinical Trials Registry India for ongoing trials. [4] Very low-dose dexamethasone to facilitate extubation of preterm babies at risk of bronchopulmonary dysplasia: the MINIDEX feasibility RCT Helen Yates,1* Virginia Chiocchia,2 Louise Linsell,2 Nicolas Orsi,3 Edmund Juszczak,2 Kathryn Johnson,4 Philip Chetcuti,4 Claire Illingworth,5 Pollyanna Hardy,6 Vaneesha Monk,7 Simon Newell8† and Mark Turner9 1Department of Neonatal Medicine, Women and Children’s Hospital, Hull Royal Infirmary, Hull, UK 2NPEU Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK 3Women’s Health Research Group, Leeds Institute of Cancer and Pathology, St James’s University Hospital, Leeds, UK 4Leeds Neonatal Service, Leeds General Infirmary, Leeds, UK 5Patient and public involvement representative 6Birmingham Clinical Trials Unit, Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK 7Department of Paediatrics, University of Oxford, John Radcliffe Hospital, Oxford, UK 8Leeds Teaching Hospitals NHS Trust, Leeds, UK 9Neonatal Unit, Liverpool Women’s Hospital, Liverpool, UK *Corresponding author Helen. [5] We assessed an integrated, multi-pronged strategy for improving youth’s timely linkage to care carried out in eight adolescent medicine clinical trials units (AMTUs) in the USA. [6] Material and methods The software was installed in the pharmacy-based Clinical Trials Unit in July 2018. [7] SETTING Clinical Trials Units in St Olav's Hospital, Trondheim and Rikshospitalet, Oslo, Norway. [8] In brief, we conducted a survey of 38 United Kingdom–registered Clinical Trials Units, reviewed a cohort of 264 published trials, observed 8 third oversight committee meetings and interviewed 52 trialists. [9] He led a highly successful AIDS Clinical Trials Unit at the University of North Carolina and was a respected leader in this national consortium who gained international recognition and respect for his work. [10] Adopt Clinical Trials Units officially and contractually recognized would be essential to bring back our nation on the top of the world health systems ranking, but yet the Italian research-dedicated infrastructures continue to be a ghost reality, deeply characterized by a continuous professional turnover and by the lack of long-term prospects. [11] Abbreviations: SUDs: substance use disorders; STIs: sexually transmitted infections; CODs: co-occurring disorders; UEC-INPRFM: clinical trials unit in addiction and mental health-national institute of psychiatry ramón de la fuente muñiz. [12] 12Cancer Research UK Clinical Trials Unit, Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham, UK. [13] Legal entity responsible for the study Medical Research Council-Clinical Trials Unit and University of Manchester. [14] Early Phase Clinical Trials Unit, Department of Oncology, University of Oxford, United Kingdom. [15] Outstanding Research Team Prize The prize was awarded to the team of the CHAPAS (Children with HIV in Africa – Pharmacokinetics and acceptability of simple antiretroviral regimens) studies, led by Professor Diana Gibb (MRC Clinical Trials Unit, United Kingdom). [16] Four main themes around trial set-up were identified from semi-structured interviews: the importance of communication and building relationships, the previous experience of the chief investigator and clinical trials units, a lack of resources and having the time and personnel required to produce trial documentation and to process trial approval requests. [17] She is an attending physician in the Cutaneous Lymphoma Clinic, Extracorporeal Photopheresis Program, and the Clinical Trials Unit where she participates in multicenter clinical trials for refractory CTCL. [18] FOCUS4 (colorectal cancer) and STAMPEDE (prostate cancer), run from the Medical Research Council Clinical Trials Unit (CTU) at UCL, are two leading UK examples of clinical trials implementing adaptive platform protocol designs. [19] JOHN ALLOTEY, WOMEN’S HEALTH RESEARCH UNIT, BARTS AND THE LONDON SCHOOL OF MEDICINE AND DENTISTRY, QUEEN MARY UNIVERSITY OF LONDON, LONDON, UK, AND NADINE MARLIN, PRAGMATIC CLINICAL TRIALS UNIT, BARTS AND THE LONDON SCHOOL OF MEDICINE AND DENTISTRY, QUEEN MARY UNIVERSITY LONDON, LONDON, UK. [20] Eicosapentaenoic acid and/or aspirin for preventing colorectal adenomas during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme: the seAFOod RCT Mark A Hull,1* Kirsty Sprange,2 Trish Hepburn,2 Wei Tan,2 Aisha Shafayat,2 Colin J Rees,3 Gayle Clifford,4 Richard F Logan,5 Paul M Loadman,6 Elizabeth A Williams,7 Diane Whitham2 and Alan A Montgomery2 on behalf of the seAFOod Collaborative Group 1Leeds Institute of Medical Research, University of Leeds, St James’s University Hospital, Leeds, UK 2Nottingham Clinical Trials Unit, Queen’s Medical Centre, School of Medicine, University of Nottingham, Nottingham, UK 3Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK 4South Tyneside District Hospital, South Tyneside NHS Foundation Trust, South Shields, UK 5Nottingham Digestive Diseases Centre, Queen’s Medical Centre, University of Nottingham, Nottingham, UK 6School of Pharmacy and Medical Sciences, Institute of Cancer Therapeutics, University of Bradford, Bradford, UK 7Department of Oncology & Metabolism, Human Nutrition Unit, The Medical School, University of Sheffield, Sheffield, UK *Corresponding author M. [21] Dormandy, who became a consultant vascular surgeon at St George’s Hospital in 1973, would later set up a clinical trials unit there for new treatments and comparisons of drug therapy. [22] Andrew D Duckworth, Margaret M McQueen, Christopher E Tuck, Jonathan H Tobias, Jeremy Mark Wilkinson, Leela C Biant, Elizabeth Claire Pulford, Stephen Aldridge, Claire Edwards, Chris P Roberts, Manoj Ramachandran, Andrew Richard McAndrew, Kenneth C K Cheng, Phillip Johnston, Nasir H Shah, Philip Mathew, John Harvie, Birgit C Hanusch, Ronnie Harkess, Aryelly Rodriguez, Gordon D Murray, and Stuart H Ralston Edinburgh Clinical Trials Unit, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK Edinburgh Orthopaedic Trauma, Royal Infirmary of Edinburgh, Edinburgh, UK Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK Trauma and Orthopaedic Surgery, University of Manchester, Manchester, UK Oxford University Hospitals NHS Foundation Trust, Headington, UK The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK Norfolk and Norwich University Hospital Foundation Trust, Norwich, UK Ipswich Hospital NHS Trust, Ipswich, UK Royal London Hospital, Barts Health NHS Trust, London, UK Royal Berkshire Hospital Foundation Trust, Reading, UK NHS Ayrshire and Arran, Ayr, UK Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Warrington and Halton Hospitals NHS Foundation Trust, Warrington, UK Queen’s Hospital, Romford, UK Raigmore Hospital, Inverness, UK South Tees, Hospitals NHS Foundation Trust, Middlesbrough, UK Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK. [23] Methods The study was carried out at a single phase I clinical trials unit. [24] ---------------------------------------------------------------------------------------------------------------Implications of Demographic Changes on Familial Care Resources -With illustrative application to Hebei province of China Zhenglian Wang, Xianling Zhang and Yi Zeng ---------------------------------------------------------------------------------------------------------------Applications of multi-state models in hematology: bridging the gap Liesbeth de Wreede (LUMC Department of Medical Statistics and Bioinformatics and DKMS, Clinical Trials Unit) In methodological papers on multi-state models in biostatistical journals, their use is often motivated by applications in the field of hematopoietic stem cell (or bone marrow) transplantation (SCT). [25] METHODS We did a 52-week, open-label, parallel-group, multicentre, superiority, randomised controlled trial at 15 primary care or hospital-based clinical trials units and primary care practices in New Zealand. [26] This research was supported by the Medical Research Council (transferred to NIHR Evaluation, Trials and Studies Coordinating Centre - Efficacy and Mechanism Evaluation; grant reference G0601705), the Swedish Cancer Society and Cancer Research UK Core Clinical Trials Unit Funding (funding reference C6716/A9894). [27] Visually Impaired OLder people’s Exercise programme for falls prevenTion (VIOLET): a feasibility study Nicola Adams,1* Dawn Skelton,2 Cathy Bailey,1 Denise Howel,3 Dorothy Coe,1 Rosy Lampitt,4 Jennifer Wilkinson,4 Tony Fouweather,3 Lex de Jong,2 Sheena Gawler,1 Vincent Deary,1 Joanne Gray,1 Heather Waterman5 and Steve Parry6 1Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK 2Institute of Applied Health Research, School of Health and Life Sciences, Centre for Living, Glasgow Caledonian University, Glasgow, UK 3Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK 4Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK 5Healthcare Sciences, Cardiff University, Cardiff, UK 6Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK *Corresponding author nicola. [28] The trial is coordinated by the CRUK Southampton Clinical Trials Unit. [29] NADINE MARLIN, PRAGMATIC CLINICAL TRIALS UNIT, BARTS AND THE LONDON SCHOOL OF MEDICINE AND DENTISTRY, QUEEN MARY UNIVERSITY LONDON, LONDON, UK, AND JOHN ALLOTEY, WOMEN’S HEALTH RESEARCH UNIT, BARTS AND THE LONDON SCHOOL OF MEDICINE AND DENTISTRY, QUEEN MARY UNIVERSITY OF LONDON, LONDON, UK. [30] This study was designed and delivered in collaboration with the Bristol Randomised Trials Collaboration (BRTC), a UK CRC-registered clinical trials unit in receipt of NIHR clinical trials unit support funding. [31] gov, the Clinical Trials Unit of the International Union Against Tuberculosis and Lung Disease, the UK Medical Research Council Clinical Trials Unit, and the Clinical Trials Registry India for ongoing trials. [32] FUNDING Cancer Research UK, The National Institute for Health Research Health Technology Assessment Programme, The MRC Clinical Trials Unit at UCL. [33] Cattolica del Sacro Cuore Italy * Andrew Copas, MRC Clinical Trials Unit at UCL United Kingdom of Great Britain and Northern Ireland Kishore Kuma Das, Gauhati Univ. [34] Adopt Clinical Trials Units officially and contractually recognized would be essential to bring back our nation on the top of the world health systems ranking, but yet the Italian research-dedicated infrastructures continue to be a ghost reality, deeply characterized by a continuous professional turnover and by the lack of long-term prospects. [35] This study is being conducted by the Clinical Trials Unit at the University of Sheffield. [36] This study compared current risk assessment and monitoring approaches in UK Clinical Trials Units (CTUs) with the published guidance and makes recommendations for risk-based monitoring in pragmatic trials. [37] This article highlights some of the key barriers to achieving this and makes suggestions on how they can be addressed within clinical trials units registered with the UK Clinical Research Collaboration. [38] The aim of this UK Clinical Trials Unit (CTU) survey was to identify which digital recruitment and retention tools are being used to support RCTs, their benefits and success characteristics. [39]

Phase Trials Unit

Early Phase Trials Unit. [1] We analyzed the overall outcomes and survival of 91 patients enrolled onto one of 14 Phase I and I/II trials for hematological malignancies at a dedicated early phase trials unit within a tertiary hematology unit. [2]

Cancer Trials Unit

Hillmen Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom; CR-UK Liverpool Cancer Trials Unit, University of Liverpool, Liverpool, United Kingdom; Liverpool Clinical Laboratories, Haemato-Oncology Diagnostic Service, Liverpool, United Kingdom; Liverpool Clinical Laboratories, Department of Blood Sciences, Liverpool, United Kingdom; Department of Haematology, Kent & Canterbury Hospital, Canterbury, United Kingdom; Russells Hall Hospital, Haematology Unit, Dudley, United Kingdom; Department of Oncology, University of Oxford, Oxford, United Kingdom; Department of Haematology, Sandwell Hospital, Birmingham, United Kingdom; Department of Haematology, Maidstone Hospital, Maidstone, United Kingdom; Department of Haematology, University Hospital Southampton, Southampton, United Kingdom; Department of Haematology & Blood Transfusion, Southend Hospital, Southend, United Kingdom; Department of Haematology, Heartlands Hospital, Birmingham, United Kingdom; Department of Haematology, Medway Maritime Hospital, Gillingham, United Kingdom; Department of Clinical Haematology, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom; Department of Clinical Haematology, Royal United Hospital, Bath, United Kingdom; Department of Haematology, Colchester General Hospital, Colchester, United Kingdom; Oncology Unit, Torbay Hospital, Torquay, United Kingdom; Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom. [1] Legal entity responsible for the study Comprehensive Cancer Trials Unit, Department of Clinical Oncology, The Chinese University of Hong Kong. [2]