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Therapeutic Development sentence examples within cardiovascular space establishing



A call to action for new global approaches to cardiovascular disease drug solutions.



A Call to Action for New Global Approaches to Cardiovascular Disease Drug Solutions.


Therapeutic Development sentence examples within despite previous work



Designing stable DNAzymes



Focal assembly


Therapeutic Development sentence examples within Future Therapeutic Development



Topographic transcriptomics of the nucleus accumbens shell: Identification and validation of fatty acid binding protein 5 as target for cocaine addiction



Ins and Outs: Recent Advancements in Membrane Protein-Mediated Prokaryotic Ferrous Iron Transport.




Therapeutic Development sentence examples within Novel Therapeutic Development



Signaling Pathways in Cancer: Therapeutic Targets, Combinatorial Treatments, and New Developments



BMP4 to increase connexin43 expression and interaction with β-catenin in glioblastoma stem cells.


Therapeutic Development sentence examples within New Therapeutic Development



Skeletal and Bone Mineral Density Features, Genetic Profile in Congenital Disorders of Glycosylation: Review



Exosomal miR‐21‐5p derived from cisplatin‐resistant SKOV3 ovarian cancer cells promotes glycolysis and inhibits chemosensitivity of its progenitor SKOV3 cells by targeting PDHA1


Therapeutic Development sentence examples within Potential Therapeutic Development



Perturbation of BRMS1 interactome reveals pathways that impact cell migration



The Curious Case of Earthworms and COVID-19


Therapeutic Development sentence examples within Cancer Therapeutic Development



lncRNA MIR210HG promotes the progression of endometrial cancer by sponging miR-337-3p/137 via the HMGA2-TGF-β/Wnt pathway



Radionuclide Therapy in Prostate Cancer: from standalone to combination PSMA theranostics.


Therapeutic Development sentence examples within Guide Therapeutic Development



Tracking the fates of iron-labeled tumor cells in vivo using Magnetic Particle Imaging



Canine Oncopanel: a capture-based, NGS platform for evaluating the mutational landscape and detecting putative driver mutations in canine cancers.


Therapeutic Development sentence examples within Promising Therapeutic Development



Abstract 2977: Organoid-T-cell co-cultures for preclinical testing of adoptive cell and cancer immunotherapy



Inhibition of host Ogr1 enhances effector CD8+ T-cell function by modulating acidic microenvironment.


Therapeutic Development sentence examples within Facilitate Therapeutic Development



Controlled spatial organization of bacterial clusters reveals cell filamentation is vital for Xylella fastidiosa biofilm formation



Excessive Laughter-like Vocalizations, Microcephaly, and Translational Outcomes in the Ube3a Deletion Rat Model of Angelman Syndrome


Therapeutic Development sentence examples within Inform Therapeutic Development



RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer



Non-destructive vacuum-assisted measurement of lung elastic modulus.


Therapeutic Development sentence examples within Targeted Therapeutic Development



Patient Segmentation in ALS Studies



Repurposing epigenetic inhibitors to target the Clostridioides difficile-specific DNA adenine methyltransferase and sporulation regulator CamA.


Therapeutic Development sentence examples within Effective Therapeutic Development



Machine learning and network-based models to identify genetic risk factors to the progression and survival of colorectal cancer



Genetics of Type 2 Diabetes: Opportunities for Precision Medicine: JACC Focus Seminar.


Therapeutic Development sentence examples within Support Therapeutic Development



Frataxin deficiency promotes endothelial senescence in pulmonary hypertension.



Retinol dehydrogenase 12 (RDH12): Role in vision, retinal disease and future perspectives.


Therapeutic Development sentence examples within Accelerate Therapeutic Development



A multimodal iPSC platform for cystic fibrosis drug testing



Defining Improvement in Nonalcoholic Steatohepatitis for Treatment Trial Endpoints: Recommendations From the Liver Forum


Therapeutic Development sentence examples within Expedient Therapeutic Development



Targeted Redesign of Suramin Analogs for Novel Antimicrobial Lead Development



Targeted redesign of suramin analogs for novel antimicrobial lead development


Therapeutic Development sentence examples within Translational Therapeutic Development



Zinc finger of the cerebellum 5 promotes colorectal cancer cell proliferation and cell cycle progression through enhanced CDK1/CDC25c signaling



Molecular Subtyping and Precision Medicine for Pancreatic Cancer


Therapeutic Development sentence examples within Preclinical Therapeutic Development



Anoctamin 5 Knockout Mouse Model Recapitulates LGMD2L Muscle Pathology and Offers Insight Into in vivo Functional Deficits.



In Memoriam for M. Flint Beal


Therapeutic Development sentence examples within Toward Therapeutic Development



Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase



Plasma microRNA signature as biomarker for disease progression in frontotemporal dementia and amyotrophic lateral sclerosis


Therapeutic Development sentence examples within Viral Therapeutic Development



Mechanistic insights into the Japanese Encephalitis Virus RNA dependent RNA polymerase protein inhibition by bioflavonoids from Azadirachta indica



Microbial community structure and composition is associated with host species and sex in Sigmodon cotton rats


Therapeutic Development sentence examples within Hampered Therapeutic Development



CD147 receptor is essential for TFF3-mediated signaling regulating colorectal cancer progression



Linking clotting and autoimmunity


Therapeutic Development sentence examples within Advance Therapeutic Development



Non-neuronal cells in amyotrophic lateral sclerosis — from pathogenesis to biomarkers



CTG-Repeat Detection in Primary Human Myoblasts of Myotonic Dystrophy Type 1


Therapeutic Development sentence examples within Antiviral Therapeutic Development



Issue Highlights



Antivirals targeting paramyxovirus membrane fusion.


Therapeutic Development sentence examples within Better Therapeutic Development



High levels of truncated RHAMM cooperate with dysfunctional p53 to accelerate the progression of pancreatic cancer



High levels of truncated RHAMM cooperate with dysfunctional p53 to accelerate the progression of pancreatic cancer.


Therapeutic Development sentence examples within Guiding Therapeutic Development



SARS‐CoV‐2 Spike Proteins: A Key Target for COVID‐19 Therapeutics Development



Diversity of Reactive Astrogliosis in CNS Pathology: Heterogeneity or Plasticity?


Therapeutic Development sentence examples within Precision Therapeutic Development



Cancer LncRNA Census 2 (CLC2): an enhanced resource reveals clinical features of cancer lncRNAs



Heterogeneity Analysis of Esophageal Squamous Cell Carcinoma in Cell Lines, Tumor Tissues and Patient-Derived Xenografts


Therapeutic Development sentence examples within Increasing Therapeutic Development



Multiscale Virtual Screening Optimization for Shotgun Drug Repurposing Using the CANDO Platform



Multiscale Virtual Screening Optimization for Shotgun Drug Repurposing Using the CANDO Platform


Therapeutic Development sentence examples within Personalized Therapeutic Development



Amyotrophic Lateral Sclerosis Survival Associates With Neutrophils in a Sex-specific Manner



Metabolomic Biomarkers Are Associated With Area of the Pons in Fragile X Premutation Carriers at Risk for Developing FXTAS


Therapeutic Development sentence examples within therapeutic development strategy



Molecular Aspects and Structure Activity Relationship of Oxytocin Agonists and Antagonist’s Role in Health



Modulación Alostérica Positiva selectiva para el receptor muscarínico M1: descubrimiento y desarrollo del compuesto VU0486846 y su importancia para el desarrollo de tratamientos para el Alzheimer y la Esquizofrenia


Therapeutic Development sentence examples within therapeutic development toward



Therapeutic Development in Charcot Marie Tooth Type 1 Disease



Therapeutic Potential of Extracellular Vesicles for Sepsis Treatment


Therapeutic Development sentence examples within therapeutic development targeting



Leukocyte immunoglobulin-like receptor subfamily B: therapeutic targets in cancer



Structure, receptor recognition and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein


Therapeutic Development sentence examples within therapeutic development aiming



Exifone Is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration.



Evolutionary plasticity of SH3 domain binding by Nef proteins of the HIV-1/SIVcpz lentiviral lineage


Therapeutic Development sentence examples within therapeutic development thematic



Long-term mortality benefit of CRT-D vs. CRT-P upgrade procedures from conventional devices without prior ventricular arrhythmias



Long-term mortality benefit of adding an ICD to CRT in non-ischemic patients


Therapeutic Development sentence examples within therapeutic development take



Proteomic portraits reveal evolutionarily conserved and divergent responses to spinal cord injury



Proteomic Portraits Reveal Evolutionarily Conserved and Divergent Responses to Spinal Cord Injury


Therapeutic Development sentence examples within therapeutic development effort



Viral Proteases as Targets for Coronavirus Disease 2019 Drug Development



The Dark Kinase Knowledgebase: an online compendium of knowledge and experimental results of understudied kinases


Therapeutic Development sentence examples within therapeutic development efficiency



Multiscale Virtual Screening Optimization for Shotgun Drug Repurposing Using the CANDO Platform



Multiscale Virtual Screening Optimization for Shotgun Drug Repurposing Using the CANDO Platform



The effects of cardiac stretch on atrial fibroblasts: Analysis of the evidence and potential role in atrial fibrillation.


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10.1016/j.copbio.2021.08.001

Enabling development, manufacturing, and regulatory approval of biotherapeutics through advances in mass spectrometry.



Persistent neuromuscular junction transmission defects in adults with spinal muscular atrophy treated with nusinersen



The Impact of Lung Proteases on Snake-Derived Antimicrobial Peptides


More Therapeutic Development sentence examples
10.1016/j.heliyon.2021.e07962

Telaprevir is a potential drug for repurposing against SARS-CoV-2: computational and in vitro studies



Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease



A Neuroprotective Locus Modulates Ischemic Stroke Infarction Independent of Collateral Vessel Anatomy



Genetics, pathogenesis and therapeutic developments for Usher syndrome type 2.


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10.1007/978-1-0716-0818-0_10

Bioluminescence Methodology for Ion Channel Studies.


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10.1158/1538-7445.AM2021-1326

Abstract 1326: Second generation androgen receptor signaling inhibitor resistant neuroendocrine like prostate cancer: A mechanistic study



Structural remodeling of SARS-CoV-2 spike protein glycans reveals the regulatory roles in receptor binding affinity



Integrated Genomics Identifies miR-181/TFAM Pathway as a Critical Driver of Drug Resistance in Melanoma



Exposing cryptic epitopes on the Venezuelan equine encephalitis virus E1 glycoprotein prior to treatment with alphavirus cross-reactive monoclonal antibody allows blockage of replication early in infection.



Tissue non-specific alkaline phosphatase (TNAP): A player in post-MI cardiac fibrosis



An Intercompany Perspective on Compatibility and In-Use Stability Studies to Enable Administration of Biopharmaceutical Drug Products.



Cell type-specific potential pathogenic genes and functional pathways in Alzheimer’s Disease



CFTR modulators: transformative therapies for cystic fibrosis.


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10.1016/j.leukres.2021.106629

Ruxolitinib discontinuation in polycythemia vera: Patient characteristics, outcomes, and salvage strategies from a large multi-institutional database.



Cancer and COVID-19: At Perilous Crossroads



Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein Based Novel Epitopes Induce Potent Immune Responses in vivo and Inhibit Viral Replication in vitro



Targeting the non‐ATP‐binding pocket of the MAP kinase p38γ mediates a novel mechanism of cytotoxicity in cutaneous T‐cell lymphoma (CTCL)



The penalty of stress - epichaperomes negatively reshaping the brain in neurodegenerative disorders.


More Therapeutic Development sentence examples
10.1016/j.bsheal.2021.07.003

SARS-CoV-2 spike protein and RNA dependent RNA polymerase as targets for drug and vaccine development: A review



Management of Malignants Gliomas: About 20 Cases Treated in the Medical Oncology Department of Fattouma Bourguiba University Hospital-Monastir



72399 Epigenetic Modification of Macrophages Contribute to Protective Memory in Against Staphylococcus aureus



A 3-month-delayed treatment with anatabine improves chronic outcomes in two different models of repetitive mild traumatic brain injury in hTau mice



Overview on the Different Patterns of Tumor Vascularization



48352 Mechanisms Underlying Lipidomic Changes in Major Depressive Disorder



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